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Simone Ciofi‐Baffoni

university of florence

47H-index
142Paper Count
6.4KCitation Count
Published Papers 58
Publication Date
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Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self-Sufficient Viral Restriction Factors
errAngewandte Chemie-International Edition
IF16.9
err2026-07-27
err0
errOAAI
errMengdi Wu; Nghi Thao Hoang; Deborah Grifagni; Meritxell Wu-Lu; Yujie Sheng; Theo Situmorang; Pei-Hsin Tai; Zheng Chen; Astrid Maluta; Mohammed Hakil; Bianca Susini; Hannah Florance; Peter-Leon Hagedoorn; John Mark Sutton; Maria-Andrea Mroginski; Simone Ciofi-Baffoni; Kourosh H. Ebrahimi
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A novel mutation in FDX2 provides insights into the pathogenesis of MEOAL mitochondrial neuromuscular disease
errCell Death & Disease
IF9.6
err2025-12-10
err0
errOAAI
errDavide Doni; Deborah Grifagni; Federica Cavion; Bianca Buchignani; Roberta Battini; Elisa Baschiera; Maria Andrea Desbats; Rosa Pasquariello; Giuseppina Covello; Eva De Pascale; Alice Boarolo; Ilaria Cestonaro; Denis Badocco; Paolo Pastore; Geppo Sartori; Oliver Stehling; Roland Lill; Filippo M. Santorelli; Leonardo Salviati; Simone Ciofi-Baffoni; Paola Costantini
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Evaluation of in vitro Antiviral Activity against different SARS-CoV-2 variants of a protease PROTAC degrader
errPharmacological Research
IF10.5
err2025-12-09
err0
errOAAI
errMirko G. Liturri; A. Bergna; A. Lai; C. Della Ventura; A. Gabrieli; I. Seravalli; S. Ciofi-Baffoni; E. Lenci; A. Trabocchi; S. Rusconi
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errSave
Optimized 13C Relaxation-Filtered Nuclear Magnetic Resonance: Harnessing Optimal Control Pulses and Ultra-High Magnetic Fields for Metalloprotein Structural Elucidation
errINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
err2025-04-19
err0
errOAAI
errQuerci, Leonardo; Burgassi, Liza; Ciofi-Baffoni, Simone; Schiavina, Marco; Piccioli, Mario
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errSave
Shedding Light on the Electron Delocalization Pathway at the [Fe2S2]2+ Cluster of FDX2
errINORGANIC CHEMISTRY
IF4.7
err2025-03-01
err0
PREAI
errQuerci, Leonardo; Fiorucci, Letizia; Grifagni, Deborah; Costantini, Paola; Ravera, Enrico; Ciofi-Baffoni, Simone; Piccioli, Mario
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A novel, orally available ferroptosis inducer targeting Fe-S assembly with significant in vivo anti-tumor efficacy
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errGreen, Yangsook Song; dos Santos, Maria Ferreira; Ciofi-Baffoni, Simone; Liu, Xiaohui; Koh, Mei Yee
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errSave
Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-01-10
err10
PREAI
errGrifagni, Deborah; Lenci, Elena; De Santis, Alessia; Orsetti, Andrea; Barracchia, Carlo Giorgio; Tedesco, Filomena; Puglielli, Raffaele Bellini; Lucarelli, Francesca; Lauriola, Angela; Assfalg, Michael; Cantini, Francesca; Calderone, Vito; Guardavaccaro, Daniele; Trabocchi, Andrea; D'Onofrio, Mariapina; Ciofi-Baffoni, Simone
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Molecular Structure of Cu(II)-Bound Amyloid-β Monomer Implicated in Inhibition of Peptide Self-Assembly in Alzheimer's Disease
errJACS AU
IF8.7
err2022-11-11
err27
errOAAI
errAbelein, Axel; Ciofi-Baffoni, Simone; Morman, Cecilia; Kumar, Rakesh; Giachetti, Andrea; Piccioli, Mario; Biverstal, Henrik
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errSave
Radical-SAM dependent nucleotide dehydratase (SAND), rectification of the names of an ancient iron-sulfur enzyme using NC-IUBMB recommendations
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2022-10-21
err3
errOAAI
errJi, Yuxuan; Wei, Li; Da, Anqi; Stark, Holger; Hagedoorn, Peter-Leon; Ciofi-Baffoni, Simone; Cowley, Sally A.; Louro, Ricardo O.; Todorovic, Smilja; Mroginski, Maria Andrea; Nicolet, Yvain; Roessler, Maxie M.; Le Brun, Nick E.; Piccioli, Mario; James, William S.; Hagen, Wilfred R.; Ebrahimi, Kourosh H.
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errSave
The Intriguing Role of Iron-Sulfur Clusters in the CIAPIN1 Protein Family
errINORGANICS
IF3
err2022-04-13
err2
errOAAI
errCiofi-Baffoni, Simone; Andreini, Claudia
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errSave
Protein-Interaction Affinity Gradient Drives [4Fe-4S] ClusterInsertion in Human Lipoyl Synthase
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-03-28
err8
errOAAI
errSaudino, Giovanni; Ciofi-Baffoni, Simone; Banci, Lucia
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errSave
Interconversion between [2Fe-2S] and [4Fe-4S] cluster glutathione complexes
errCHEMICAL COMMUNICATIONS
IF4.2
err2022-01-01
err10
errOAAI
errInvernici, Michele; Selvolini, Giulia; Silva, Jose Malanho; Marrazza, Giovanna; Ciofi-Baffoni, Simone; Piccioli, Mario
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errSave
In Cellulo Mossbauer and EPR Studies Bring New Evidence to the Long-Standing Debate on Iron-Sulfur Cluster Binding in Human Anamorsin
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2021-05-24
err10
errOAAI
errMatteucci, Sara; Camponeschi, Francesca; Clemancey, Martin; Ciofi-Baffoni, Simone; Blondin, Genevieve; Banci, Lucia
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errSave
GLRX3 Acts as a [2Fe-2S] Cluster Chaperone in the Cytosolic Iron- Sulfur Assembly Machinery Transferring [2Fe-2S] Clusters to NUBP1
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-05-20
err22
errOAAI
errCamponeschi, Francesca; Prusty, Nihar Ranjan; Heider, Sabine Annemarie Elisabeth; Ciofi-Baffoni, Simone; Banci, Lucia
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errSave
Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery
errSCIENTIFIC REPORTS
IF3.9
err2019-12-12
err22
errOAAI
errNasta, Veronica; Vela, Stefano; Gourdoupis, Spyridon; Ciofi-Baffoni, Simone; Svergun, Dmitri, I; Banci, Lucia
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errSave
A pathway for assembling [4Fe-4S]2+ clusters in mitochondrial iron-sulfur protein biogenesis
errFEBS JOURNAL
IF4.2
err2019-12-03
err33
errOAAI
errNasta, Veronica; Suraci, Dafne; Gourdoupis, Spyridon; Ciofi-Baffoni, Simone; Banci, Lucia
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IBA57 Recruits ISCA2 to Form a [2Fe-2S] Cluster-Mediated Complex
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-10-01
err44
errOAAI
errGourdoupis, Spyridon; Nasta, Veronica; Calderone, Vito; Ciofi-Baffoni, Simone; Banci, Lucia
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errSave
Anamorsin/Ndor1 Complex Reduces [2Fe-2S]-MitoNEET via a Transient Protein-Protein Interaction
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2017-07-06
err34
errOAAI
errCamponeschi, Francesca; Ciofi-Baffoni, Simone; Banci, Lucia
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errSave
[4Fe-4S] Cluster Assembly in Mitochondria and Its Impairment by Copper
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2017-01-03
err124
PREAI
errBrancaccio, Diego; Gallo, Angelo; Piccioli, Mario; Novellino, Ettore; Ciofi-Baffoni, Simone; Banci, Lucia
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errSave
Mitochondrial Bol1 and Bol3 function as assembly factors for specific iron-sulfur proteins
errELIFE
IF0
err2016-08-17
err100
errOAAI
errUzarska, Marta A.; Nasta, Veronica; Weiler, Benjamin D.; Spantgar, Farah; Ciofi-Baffoni, Simone; Saviello, Maria Rosaria; Gonnelli, Leonardo; Muehlenhoff, Ulrich; Banci, Lucia; Lill, Roland
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Research Directions

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Co-authors
Cooperation Journals
I
Ivano Bertini
H-index: 115 · Papers: 1.4K
R
Roland Lill
H-index: 105 · Papers: 306
D
Dmitri I. Svergun
H-index: 99 · Papers: 828
C
Claudio Luchinat
H-index: 89 · Papers: 1.0K
D
Dennis R. Winge
H-index: 87 · Papers: 271
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