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An integrated analysis of three medulloblastoma clinical trials refines risk-stratification approaches for reducing toxicity and improving survival Smith, Kyle S.; Dhanda, Sandeep K.; Billups, Catherine A.; Sioson, Edgar; Lu, Congyu; Peraza, Airen Zaldivar; Gangwani, Karishma; Li, Yimei; Li, Qian; Lin, Tong; Michalski, Jeff M.; Packer, Roger J.; Olson, James M.; Leary, Sarah E. S.; Fouladi, Maryam; Gajjar, Amar; Zhou, Xin; Onar-Thomas, Arzu; Northcott, Paul A.; Robinson, Giles W. Share Save
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Effect of bevacizumab on non-target intracranial meningiomas and non-vestibular schwannomas in NF2-related schwannomatosis: NF104 Nakhate, Vihang; Ly, Ina; Muzikansky, Alona; Rapalino, Otto; Allen, Jeffrey C.; Blakeley, Jaishri O.; Campian, Jian L.; Clapp, D. Wade; Dhall, Girish; Jain, Rakesh K.; Karajannis, Matthias A.; Packer, Roger J.; Tonsgard, James; Ullrich, Nicole J.; Korf, Bruce R.; Fisher, Michael J.; Plotkin, Scott R.; Neurofibromatosis Clinical Trials Consortium Share Save
Molecular Testing for the World Health Organization Classification of Central Nervous System Tumors: A Review Horbinski, Craig; Solomon, David A.; Lukas, Rimas V.; Packer, Roger J.; Brastianos, Priscilla; Wen, Patrick Y.; Snuderl, Matija; Berger, Mitchel S.; Chang, Susan; Fouladi, Maryam; Phillips, Joanna J.; Nabors, Burt; Brat, Daniel J.; Huse, Jason T.; Aldape, Kenneth; Sarkaria, Jann N.; Holdhoff, Matthias; Burns, Terry C.; Peters, Katherine B.; Mellinghoff, Ingo K.; Arons, David; Galanis, Evanthia Share Save
SONODYNAMIC THERAPY (SDT) USING INTRAVENOUS 5-AMINOLEVULINIC ACID WITH NON-ABLATIVE FOCUSED ULTRASOUND FOR THE TREATMENT OF DIFFUSE INTRINSIC PONTINE GLIOMAS IN PEDIATRICS: INITIAL SAFETY AND OUTCOMES THE MULTICENTER SDT-201 TRIAL Kilburn, Lindsay; Keating, Robert; Patel, Nirali; Fonseca, Adriana; Donoho, Dan; Oluigbo, Chima; Myseros, John; Narsinh, Kazim; Mueller, Sabine; Ho, Winson; Khatib, Ziad; Niazi, Toba; Clanton, Ryan; Henry, Lenora; Potter, Wyatt; Marcus, Stuart; Benaim, Ely; Packer, Roger; Syed, Hasan Share Save
Central nervous system tumors in adolescents and young adults: A Society for Neuro-Oncology consensus review on diagnosis, management, and future directions Lim-Fat, Mary Jane; Bennett, Julie; Ostrom, Quinn; Touat, Mehdi; Franceschi, Enrico; Schulte, Jessica; Bindra, Ranjit S.; Fangusaro, Jason; Dhall, Girish; Nicholson, James; Jackson, Sadhana; Davidson, Tom Belle; Calaminus, Gabriele; Robinson, Giles; Whittle, James R.; Hau, Peter; Ramaswamy, Vijay; Pajtler, Kristian W.; Ruda, Roberta; Foreman, Nicholas K.; Hervey-Jumper, Shawn L.; Das, Sunit; Dirks, Peter; Bi, Wenya Linda; Huang, Annie; Merchant, Thomas E.; Fouladi, Maryam; Aldape, Kenneth; van den Bent, Martin J.; Packer, Roger J.; Miller, Julie J.; Reardon, David A.; Chang, Susan M.; Haas-Kogan, Daphne; Tabori, Uri; Hawkins, Cynthia; Monje, Michelle; Wen, Patrick Y.; Bouffet, Eric; Yeo, Kee Kiat Share Save
MR-guided focused ultrasound in pediatric neurosurgery: current insights, technical challenges, and lessons learned from 45 treatments at Children's National Hospital Keating, Gregory F.; Chesney, Kelsi M.; Patel, Nirali; Kilburn, Lindsay; Fonseca, Adriana; Packer, Roger J.; Challa, Chaitanya; O'Brien, Patrick F.; Donoho, Daniel A.; Myseros, John S.; Oluigbo, Chima; Keating, Robert F.; Syed, Hasan R. Share Save
Tumor volume features predict survival outcomes for patients diagnosed with diffuse intrinsic pontine glioma Spencer, D'Andre; Bonner, Erin R.; Tor-Diez, Carlos; Liu, Xinyang; Bougher, Kristen; Prasad, Rachna; Gordish-Dressman, Heather; Eze, Augustine; Packer, Roger J.; Nazarian, Javad; Linguraru, Marius George; Bornhorst, Miriam Share Save
Early prognostication of overall survival for pediatric diffuse midline gliomas using MRI radiomics and machine learning: A two-center study Liu, Xinyang; Jiang, Zhifan; Roth, Holger R.; Anwar, Syed Muhammad; Bonner, Erin R.; Mahtabfar, Aria; Packer, Roger J.; Kazerooni, Anahita Fathi; Bornhorst, Miriam; Linguraru, Marius George Share Save
INTERIM CLINICAL, PHARMACOKINETIC, AND TECHNICAL REPORT OF A PHASE 2 STUDY OF SONODYNAMIC THERAPY (SDT) USING SONALA-001 TOGETHER WITH MR-GUIDED LOW-INTENSITY FOCUSED ULTRASOUND (MRGFUS) IN CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) Syed, Hasan R.; Packer, Roger J.; Fonseca, Adriana; Keating, Robert F.; Mueller, Sabine; Narsinh, Kazim; Ho, Winson; Niazi, Toba; Fenn, Peter; Clanton, Ryan; Henry, Lenora; Potter, Wyatt; Andresen, Corina; Marcus, Stuart; Benaim, Ely; Kilburn, Lindsay Share Save
PNOC008: A PILOT TRIAL TESTING THE CLINICAL BENEFIT OF USING MOLECULAR PROFILING TO DETERMINE AN INDIVIDUALIZED TREATMENT PLAN IN CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED HIGH-GRADE GLIOMA (EXCLUDING DIFFUSE INTRINSIC PONTINE GLIOMA) Franson, Andrea T.; Kilburn, Lindsay B.; Cooney, Tab M.; Stoller, Schuyler; Reddy, Alyssa T.; Banerjee, Anu; Packer, Roger J.; Bendel, Anne E.; Skrypek, Mary M.; Minturn, Jane E.; Abdelbaki, Mohamed S.; Whipple, Nicholas S.; Chan, Priya; Crawford, John R.; Crotty, Erin E.; Waanders, Angela J.; Elster, Jennifer D.; Raabe, Eric H.; George, Elizabeth; Pinto, Soniya N.; Vossough, Arastoo; Kraya, Adam A.; Prados, Michael; Kline, Cassie; Nazarian, Javad; Solomon, David A.; Long-Boyle, Janel R.; Molinaro, Annette M.; Waszak, Sebastian M.; Mueller, Sabine Share Save
PNOC016: INTRATUMORAL PHARMACOKINETICS AND PHARMACODYNAMIC (PK/PD) RESULTS FROM A TARGET VALIDATION STUDY OF A NOVEL PAN-HDAC AND PI3K INHIBITOR, FIMEPINOSTAT, IN CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG), RECURRENT MEDULLOBLASTOMA (MB), AND RECURRENT HIGH-GRADE GLIOMA (HGG) Kline, Cassie; Crawford, John R.; Reddy, Alyssa T.; Gerber, Nicolas; Stucklin, Ana Guerreiro; Kilburn, Lindsay; Packer, Roger; Margol, Ashley; Crotty, Erin; Sayour, Elias; Franson, Andrea; Phillips, Joanna; Singh, Shefali; Hamanishi, Erin; Lee, Christopher; Bhatia, Aashim; George, Elizabeth; Rauschecker, Andreas; Molinaro, Annette; Prados, Michael; Nazarian, Javad; Venneti, Sriram; Wechsler-Reya, Robert; Mueller, Sabine Share Save
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TARGETED THERAPY OF PEDIATRIC HIGH GRADE GLIOMAS Papusha, Ludmila; Druy, Alexander; Salnikova, Ekaterina; Zaytseva, Margarita; Panferova, Agnesa; Vilesova, Irina; Flegontov, Andrey; Kasich, Igor; Merishavyan, Artur; Sysoev, Andrey; Degtyarev, Vitaly; Koldasheva, Marina; Sanakoeva, Agunda; Artemov, Anton; Procvetkina, Anastasia; Karachunskiy, Alexander; Hwang, Eugene; Packer, Roger; Novichkova, Galina Share Save
CLINICAL AND MOLECULAR CHARACTERIZATION OFDICER-MUTANT CENTRAL NERVOUS SYSTEM SARCOMA Dowiak, Alexis; Williamson, Lane; Povilaikaite, Julija; Cabrera, Edgar; Aponte, Nelson; Garcia, Johnny; Quiroz, Lina; Pina, Martha; Martinez, Cindy; Valencia, Diana; Barragan, Liliana; Resendiz, Alma Benito; Magelssen, Henriette; Trujillo, Angela; Osorio, Diana; Figueredo, Oscar; Packer, Roger; Sarmiento, Isabel; Suarez, Amaranto; Mushtaq, Naureen; Abdullaev, Zied; Poria, Dipak; Bartels, Ute; Bouffett, Eric; Polo, Barbara Rivera; Aldape, Kenneth; Ramaswamy, Vijay; Fonseca, Adriana Share Save
EARLY INSIGHTS FROM PNOC027: PERSONALIZED TREATMENT APPROACHES BASED ON REAL-TIME DRUG SCREENING AND GENOMIC TESTING IN PEDIATRIC AND ADOLESCENT PATIENTS WITH RECURRENT MEDULLOBLASTOMA Shatara, Margaret; Paul, Megan R.; Long-Boyle, Janel R.; Meyer, Ashley; Raber, Shannon; Yeh-Nayre, Lanipua; Jalkanen, Aimee; Kilburn, Lindsay B.; Packer, Roger J.; Elster, Jennifer D.; Reddy, Alyssa T.; Koschmann, Carl; Kraya, Adam; Resnick, Adam C.; Prados, Michael; Kline, Cassie; Mueller, Sabine; Wechsler-Reya, Robert J.; Rubin, Joshua B. Share Save
A PHASE 1/2 STUDY ASSESSING SAFETY AND PHARMACOKINETICS OF CEMIPLIMAB IN PEDIATRIC PATIENTS WITH RELAPSED OR REFRACTORY SOLID OR CENTRAL-NERVOUS-SYSTEM TUMORS AND SAFETY AND EFFICACY OF CEMIPLIMAB IN COMBINATION WITH RADIOTHERAPY IN PATIENTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA, NEWLY DIAGNOSED HIGH-GRADE GLIOMA, OR RECURRENT HIGH-GRADE GLIOMA Kline, Cassie; Schoenfeld, Jonathan D.; Gajjar, Amar; Tinkle, Christopher; Margol, Ashley; Davidson, Tom; Bendel, Anne; Skrypek, Mary; Kilburn, Lindsay; Packer, Roger; Reddy, Alyssa T.; Abdelbaki, Mohamed S.; Rubin, Josh; Sayour, Elias; Mitchell, Duane; Chi, Susan; Waanders, Angela J.; Elster, Jennifer; Baxter, Patricia; Crotty, Erin; Cohen, Kenneth; Moertel, Christopher; Franson, Andrea T.; Whipple, Nicholas S.; Bansal, Shikha; Jankovic, Vladimir; Kaul, Manika; Paccaly, Anne; Zhong, Bob; Schmidt, Tamara; Lowy, Israel; Seebach, Frank; Liu, Kevin; Gunasti, Lauren; Morinigo, Denise; Singh, Shefali; Shai, Anny; Phillips, Joanna; Filbin, Mariella; Nazarian, Javad; Catalano, Paul; Prados, Michael; Haas-Kogan, Daphne; Magnan, Heather; Mueller, Sabine Share Save
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