Not logged inCLN-619, a MICA/B monoclonal antibody that promotes innate immune cell-mediated antitumor activity
Whalen, Kerry A.; Henry, Catherine C.; Mehta, Naveen K.; Rakhra, Kavya; Yalcin, Safak; Meetze, Kristan; Gibson, Neil W.; Baeuerle, Patrick A.; Michaelson, Jennifer S. .png)
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SaveShare Save Share Save Share Save Share Save Share Save Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumorsDing, Jian; Guyette, Sarah; Schrand, Brett; Geirut, Jessica; Horton, Holly; Guo, Guangwu; Delgoffe, Greg; Menk, Ashley; Baeuerle, Patrick A.; Hofmeister, Robert; Tighe, Robert Share Save Share Save TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid TumorsAustin, Richard J.; Lemon, Bryan D.; Aaron, Wade H.; Barath, Manasi; Culp, Patricia A.; DuBridge, Robert B.; Evnin, Luke B.; Jones, Adrie; Panchal, Anand; Patnaik, Purbasa; Ramakrishnan, Vanitha; Rocha, Sony S.; Seto, Pui; Sexton, Kenneth; Strobel, Kathryn L.; Wall, Russell; Yu, Stephen; Yu, Timothy Z.; Law, Che-Leung; Baeuerle, Patrick A.; Wesche, Holger Share Save Share Save Preclinical evaluation of TC-110: CD19-specific T cell receptor (TCR) fusion construct (TRuC™) T cell for the treatment of hematologic malignanciesHorton, Holly; Ding, Jian; Shah, Seema; Gierut, Jessica; Thorausch, Niko; Morath, Anna; Shamel, Wolfgang; Maus, Marcela; Baeuerle, Patrick; Hofmeister, Robert; Getts, Daniel R. Share Save Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor responseBaeuerle, Patrick A.; Ding, Jian; Patel, Ekta; Thorausch, Niko; Horton, Holly; Gierut, Jessica; Scarfo, Irene; Choudhary, Rashmi; Kiner, Olga; Krishnamurthy, Janani; Le, Bonnie; Morath, Anna; Baldeyiano, G. Christian; Quinn, Justin; Tayares, Patrick; Wei, Qi; Weiler, Solly; Maus, Marcela, V; Getts, Daniel; Schamel, Wolfgang W.; Hofmeister, Robert Share Save Antiviral Activity of HIV gp120-Targeting Bispecific T Cell Engager Antibody ConstructsBrozy, Johannes; Schlaepfer, Erika; Mueller, Christina K. S.; Rochat, Mary-Aude; Rampini, Silvana K.; Myburgh, Renier; Raum, Tobias; Kufer, Peter; Baeuerle, Patrick A.; Muenz, Markus; Speck, Roberto F. Share Save HPN536, a T cell-engaging, mesothelin/CD3-specific TriTAC for the treatment of solid tumorsAustin, Richard; Aaron, Wade; Baeuerle, Patrick; Barath, Manasi; Jones, Adrie; Jones, Susan D.; Law, Che-Leung; Kwant, Kathryn; Lemon, Bryan; Muchnik, Anna; Sexton, Kenneth; Tatalick, Laurie; Wesche, Holger; Yu, Timothy Share Save Preclinical evaluation of mesothelin-specific T cell receptor (TCR) fusion constructs (TRuC™s) utilizing the signaling power of the complete TCR complex: A new opportunity for solid tumor therapyDing, Jian; Patel, Ekta; Tavares, Patrick; Quinn, Justin; Choudhary, Rashmi; Le, Bonnie; Kiner, Olga; Weiler, Solly; Getts, Daniel R.; Baeuerle, Patrick; Hofmeister, Robert Share Save HPN424, a half-life extended, PSMA/CD3-specific TriTAC for the treatment of metastatic prostate cancerLemon, Bryan; Aaron, Wade; Austin, Richard; Baeuerle, Patrick; Barath, Manasi; Jones, Adrie; Jones, Susan D.; Kwant, Kathryn; Law, Che-Leung; Muchnik, Anna; Sexton, Kenneth; Tatalick, Laurie; Wesche, Holger; Yu, Timothy Share Save Characterization of a novel class of engineered (TCR) fusion constructs (TRuC™s) aimed to treat solid tumorsPatel, Ekta; Ding, Jian; Thorausch, Nikolaus; Krishnamurthy, Janani; Choudhary, Rashmi; Weiler, Solly; Le, Bonnie; Tavares, Patrick; Zieba, Adam; Quinn, Justin; Wang, Yan; Schamel, Wolfgang; Scarfo, Irene; Maus, Marcela; Baeuerle, Patrick; Getts, Dainel; Hofmeister, Robert Share Save Share Save Changes in clinical laboratory parameters and pharmacodynamic markers in response to blinatumomab treatment of patients with relapsed/refractory ALLNaegele, Virginie; Kratzer, Andrea; Zugmaier, Gerhard; Holland, Chris; Hijazi, Youssef; Topp, Max S.; Goekbuget, Nicola; Baeuerle, Patrick A.; Kufer, Peter; Wolf, Andreas; Klinger, Matthias Share Save Share Save 
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