Not logged inDrug-controlled CAR T cells through the regulation of cell-cell interactions
Scheller, Leo; Attianese, Greta Maria Paola Giordano; Castellanos-Rueda, Rocio; Di Roberto, Raphael B.; Barden, Markus; Triboulet, Melanie; Hafezi, Morteza; Ash, Sarah; Shui, Sailan; Cribioli, Elisabetta; Reichenbach, Patrick; Maillard, Jimmy; Marchand, Anthony; Georgeon, Sandrine; Wolf, Benita; Abken, Hinrich; Reddy, Sai; Correia, Bruno E.; Irving, Melita .png)
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SaveHighly efficient gene knockout in tumor-infiltrating lymphocytes by adenine base editingHafezi, Morteza; Genolet, Raphael; Hadadi, Leila; Chap, Bovannak Stewen; Bobisse, Sara; Attianese, Greta Maria Paola Giordano; El Jorfi, Hanan; Cropp, Daniela; Pericou, Laetitia; Arnaud, Marion; Scholten, Kirsten; Maurouard, Typhanie; Laniti, Denarda Dangaj; Harari, Alexandre; Gentner, Bernhard; Irving, Melita; Coukos, George Share Save Share Save Share Save Dual ON/OFF- switch chimeric antigen receptor controlled by two clinically approved drugsAttianese, Greta Maria Paola Giordano; Shui, Sailan; Cribioli, Elisabetta; Triboulet, Melanie; Scheller, Leo; Hafezi, Morteza; Reichenbach, Patrick; Gainza, Pablo; Georgeon, Sandrine; Correia, Bruno E.; Irving, Melita Share Save Share Save Validation of the C-X-C chemokine receptor 3 (CXCR3) as a target for PET imaging of T cell activationMartin, Sebastian; Wendlinger, Lennard; Zitti, Beatrice; Hicham, Mehdi; Postupalenko, Viktoriia; Marx, Leo; Giordano-Attianese, Greta; Cribioli, Elisabetta; Irving, Melita; Litvinenko, Alexandra; Faizova, Radmila; Viertl, David; Schottelius, Margret Share Save Combining SiRP α decoy-coengineered T cells and antibodies augments macrophage-mediated of tumor cellsStefanidis, Evangelos; Semilietof, Aikaterini; Pujol, Julien; Seijo, Bili; Scholten, Kirsten; Zoete, Vincent; Michielin, Olivier; Sandaltzopoulos, Raphael; Coukos, George; Irving, Melita Share Save Activation of the transcription factor NFAT5 in the tumor microenvironment enforces CD8+ T cell exhaustionTille, Laure; Cropp, Daniela; Charmoy, Melanie; Reichenbach, Patrick; Andreatta, Massimo; Wyss, Tania; Bodley, Gabrielle; Crespo, Isaac; Nassiri, Sina; Lourenco, Joao; Leblond, Marine M.; Lopez-Rodriguez, Cristina; Speiser, Daniel E.; Coukos, George; Irving, Melita; Carmona, Santiago J.; Held, Werner; Verdeil, Gregory Share Save Share Save Neoantigen-specific CD8 T cells with high structural avidity preferentially reside in and eliminate tumorsSchmidt, Julien; Chiffelle, Johanna; Perez, Marta A. S.; Magnin, Morgane; Bobisse, Sara; Arnaud, Marion; Genolet, Raphael; Cesbron, Julien; Barras, David; Navarro Rodrigo, Blanca; Benedetti, Fabrizio; Michel, Alexandra; Queiroz, Lise; Baumgaertner, Petra; Guillaume, Philippe; Hebeisen, Michael; Michielin, Olivier; Nguyen-Ngoc, Tu; Huber, Florian; Irving, Melita; Tissot-Renaud, Stephanie; Stevenson, Brian J.; Rusakiewicz, Sylvie; Dangaj Laniti, Denarda; Bassani-Sternberg, Michal; Rufer, Nathalie; Gfeller, David; Kandalaft, Lana E.; Speiser, Daniel E.; Zoete, Vincent; Coukos, George; Harari, Alexandre Share Save Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cellsCorria-Osorio, Jesus; Carmona, Santiago J. J.; Stefanidis, Evangelos; Andreatta, Massimo; Ortiz-Miranda, Yaquelin; Muller, Tania; Rota, Ioanna A. A.; Crespo, Isaac; Seijo, Bili; Castro, Wilson; Jimenez-Luna, Cristina; Scarpellino, Leonardo; Ronet, Catherine; Spill, Aodrenn; Lanitis, Evripidis; Romero, Pedro; Luther, Sanjiv A. A.; Irving, Melita; Coukos, George Share Save A lentiviral vector for the production of T cells with an inducible transgene and a constitutively expressed tumour-targeting receptorReichenbach, Patrick; Giordano Attianese, Greta Maria Paola; Ouchen, Khaoula; Cribioli, Elisabetta; Triboulet, Melanie; Ash, Sarah; Saillard, Margaux; Vuillefroy de Silly, Romain; Coukos, George; Irving, Melita Share Save TCR sequencing and cloning methods for repertoire analysis and isolation of tumor-reactive TCRsGenolet, Raphael; Bobisse, Sara; Chiffelle, Johanna; Arnaud, Marion; Petremand, Remy; Queiroz, Lise; Michel, Alexandra; Reichenbach, Patrick; Cesbron, Julien; Auger, Aymeric; Baumgaertner, Petra; Guillaume, Philippe; Schmidt, Julien; Irving, Melita; Kandalaft, Lana E.; Speiser, Daniel E.; Coukos, George; Harari, Alexandre Share Save A bioluminescent-based probe for in vivo non-invasive monitoring of nicotinamide riboside uptake reveals a link between metastasis and NAD plus metabolismMaric, Tamara; Bazhin, Arkadiy; Khodakivskyi, Pavlo; Mikhaylov, Georgy; Solodnikova, Ekaterina; Yevtodiyenko, Aleksey; Attianese, Greta Maria Paola Giordano; Coukos, George; Irving, Melita; Joffraud, Magali; Canto, Carles; Goun, Elena Share Save Share Save Share Save Share Save Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitorsRoehrig, Ute F.; Majjigapu, Somi Reddy; Vogel, Pierre; Reynaud, Aline; Pojer, Florence; Dilek, Nahzli; Reichenbach, Patrick; Ascencao, Kelly; Irving, Melita; Coukos, George; Michielin, Olivier; Zoete, Vincent Share Save Share Save 
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