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Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases (vol 12, 5955, 2021) Prakadan, Sanjay M.; Alvarez-Breckenridge, Christopher A.; Markson, Samuel C.; Kim, Albert E.; Klein, Robert H.; Nayyar, Naema; Navia, Andrew W.; Kuter, Benjamin M.; Kolb, Kellie E.; Bihun, Ivanna; Mora, Joana L.; Bertalan, Mia Solana; Shaw, Brian; White, Michael; Kaplan, Alexander; Stocking, Jackson H.; Wadsworth, Marc H., II; Lee, Eudocia Q.; Chukwueke, Ugonma; Wang, Nancy; Subramanian, Megha; Rotem, Denisse; Cahill, Daniel P.; Adalsteinsson, Viktor A.; Miller, Jeffrey W.; Sullivan, Ryan J.; Carter, Scott L.; Brastianos, Priscilla K.; Shalek, Alex K. Share Save
Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases Prakadan, Sanjay M.; Alvarez-Breckenridge, Christopher A.; Markson, Samuel C.; Kim, Albert E.; Klein, Robert H.; Nayyar, Naema; Navia, Andrew W.; Kuter, Benjamin M.; Kolb, Kellie E.; Bihun, Ivanna; Mora, Joana L.; Bertalan, Mia Solana; Shaw, Brian; White, Michael; Kaplan, Alexander; Stocking, Jackson H.; Wadsworth, Marc H., II; Lee, Eudocia Q.; Chukwueke, Ugonma; Wang, Nancy; Subramanian, Megha; Rotem, Denisse; Cahill, Daniel P.; Adalsteinsson, Viktor A.; Miller, Jeffrey W.; Sullivan, Ryan J.; Carter, Scott L.; Brastianos, Priscilla K.; Shalek, Alex K. Share Save
Phase II study of ipilimumab and nivolumab in leptomeningeal carcinomatosis Brastianos, Priscilla K.; Strickland, Matthew R.; Lee, Eudocia Quant; Wang, Nancy; Cohen, Justine V.; Chukwueke, Ugonma; Forst, Deborah Anne; Eichler, April; Overmoyer, Beth; Lin, Nancy U.; Chen, Wendy Y.; Bardia, Aditya; Juric, Dejan; Dagogo-Jack, Ibiayi; White, Michael D.; Dietrich, Jorg; Nayyar, Naema; Kim, Albert E.; Alvarez-Breckenridge, Christopher; Mahar, Maura; Mora, Joana L.; Nahed, Brian V.; Jones, Pamela S.; Shih, Helen A.; Gerstner, Elizabeth R.; Giobbie-Hurder, Anita; Carter, Scott L.; Oh, Kevin; Cahill, Daniel P.; Sullivan, Ryan J. Share Save
Palbociclib demonstrates intracranial activity in progressive brain metastases harboring cyclin-dependent kinase pathway alterations Brastianos, Priscilla K.; Kim, Albert E.; Wang, Nancy; Lee, Eudocia Q.; Ligibel, Jennifer; Cohen, Justine, V; Chukwueke, Ugonma N.; Mahar, Maura; Oh, Kevin; White, Michael D.; Shih, Helen A.; Forst, Deborah; Gainor, Justin F.; Heist, Rebecca S.; Gerstner, Elizabeth R.; Batchelor, Tracy T.; Lawrence, Donald; Ryan, David P.; Iafrate, A. John; Giobbie-Hurder, Anita; Santagata, Sandro; Carter, Scott L.; Cahill, Daniel P.; Sullivan, Ryan J. Share Save
Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome Kennedy, Alyssa L.; Myers, Kasiani C.; Bowman, James; Gibson, Christopher J.; Camarda, Nicholas D.; Furutani, Elissa; Muscato, Gwen M.; Klein, Robert H.; Ballotti, Kaitlyn; Liu, Shanshan; Harris, Chad E.; Galvin, Ashley; Malsch, Maggie; Dale, David; Gansner, John M.; Nakano, Taizo A.; Bertuch, Alison; Vlachos, Adrianna; Lipton, Jeffrey M.; Castillo, Paul; Connelly, James; Churpek, Jane; Edwards, John R.; Hijiya, Nobuko; Ho, Richard H.; Hofmann, Inga; Huang, James N.; Keel, Sioban; Lamble, Adam; Lau, Bonnie W.; Norkin, Maxim; Stieglitz, Elliot; Stock, Wendy; Walkovich, Kelly; Boettcher, Steffen; Brendel, Christian; Fleming, Mark D.; Davies, Stella M.; Weller, Edie A.; Bahl, Christopher; Carter, Scott L.; Shimamura, Akiko; Lindsley, R. Coleman Share Save
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Inactivation of Fbxw7 Impairs dsRNA Sensing and Confers Resistance to PD-1 Blockade Gstalder, Cecile; Liu, David; Miao, Diana; Lutterbach, Bart; DeVine, Alexander L.; Lin, Chenyu; Shettigar, Megha; Pancholi, Priya; Buchbinder, Elizabeth, I; Carter, Scott L.; Manos, Michael P.; Rojas-Rudilla, Vanesa; Brennick, Ryan; Gjini, Evisa; Chen, Pei-Hsuan; Lako, Ana; Rodig, Scott; Yoon, Charles H.; Freeman, Gordon J.; Barbie, David A.; Hodi, F. Stephen; Miles, Wayne; Van Allen, Eliezer M.; Haq, Rizwan Share Save
Identifying genomic drivers of lung adenocarcinoma brain metastases Nayyar, Naema; Shih, David J.; Bihun, Ivanna; Dagogo-Jack, Ibiayi; Gill, Corey M.; Aquilanti, Elisa; Bertalan, Mia; Kaplan, Alexander; D'Andrea, Megan R.; Chukwueke, Ugonma; Alvarez-Breckenridge, Christopher; Lastrapes, Matthew; Kuter, Ben; Strickland, Matthew R.; Martinez-Gutierrez, Juan Carlos; Nagabhushan, Deepika; De Sauvage, Magali; White, Michael D.; Castro, Brandyn A.; Hoang, Kaitlin; Paek, Sun Ha; Park, Sun Hye; Martinez-Lage, Maria; Berghoff, Anna S.; Merrill, Parker; Gerstner, Elizabeth R.; Batchelor, Tracy T.; Frosch, Matthew P.; Frazier, Ryan P.; Borger, Darrell R.; Iafrate, A. John; Santagata, Sandro; Preusser, Matthias; Cahill, Daniel P.; Carter, Scott L.; Brastianos, Priscilla K. Share Save
Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis (vol 51, pg 931, 2020) Brastianos, Priscilla K.; Lee, Eudocia Quant; Cohen, Justine V.; Tolaney, Sara M.; Lin, Nancy U.; Wang, Nancy; Chukwueke, Ugonma; White, Michael D.; Nayyar, Naema; Kim, Albert; Alvarez-Breckenridge, Christopher; Krop, Ian; Mahar, Maura Keeley; Bertalan, Mia S.; Shaw, Brian; Mora, Joana L.; Goss, Nathaniel; Subramanian, Megha; Nayak, Lakshmi; Dietrich, Jorg; Forst, Deborah A.; Nahed, Brian V.; Batchelor, Tracy T.; Shih, Helen A.; Gerstner, Elizabeth R.; Moy, Beverly; Lawrence, Donald; Giobbie-Hurder, Anita; Carter, Scott L.; Oh, Kevin; Cahill, Daniel P.; Sullivan, Ryan J. Share Save
Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis Brastianos, Priscilla K.; Lee, Eudocia Quant; Cohen, Justine V.; Tolaney, Sara M.; Lin, Nancy U.; Wang, Nancy; Chukwueke, Ugonma; White, Michael D.; Nayyar, Naema; Kim, Albert; Alvarez-Breckenridge, Christopher; Krop, Ian; Mahar, Maura Keeley; Bertalan, Mia S.; Shaw, Brian; Mora, Joana L.; Goss, Nathaniel; Subramanian, Megha; Nayak, Lakshmi; Dietrich, Jorg; Forst, Deborah A.; Nahed, Brian V.; Batchelor, Tracy T.; Shih, Helen A.; Gerstner, Elizabeth R.; Moy, Beverly; Lawrence, Donald; Giobbie-Hurder, Anita; Carter, Scott L.; Oh, Kevin; Cahill, Daniel P.; Sullivan, Ryan J. Share Save
Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases Zimmer, Alexandra S.; Steinberg, Seth M.; Smart, Dee Dee; Gilbert, Mark R.; Armstrong, Terri S.; Burton, Eric; Houston, Nicole; Biassou, Nadia; Gril, Brunilde; Brastianos, Priscilla K.; Carter, Scott; Lyden, David; Lipkowitz, Stanley; Steeg, Patricia S. Share Save
Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma Shih, David J. H.; Nayyar, Naema; Bihun, Ivanna; Dagogo-Jack, Ibiayi; Gill, Corey M.; Aquilanti, Elisa; Bertalan, Mia; Kaplan, Alexander; D'Andrea, Megan R.; Chukwueke, Ugonma; Ippen, Franziska Maria; Alvarez-Breckenridge, Christopher; Camarda, Nicholas D.; Lastrapes, Matthew; McCabe, Devin; Kuter, Ben; Kaufman, Benjamin; Strickland, Matthew R.; Martinez-Gutierrez, Juan Carlos; Nagabhushan, Deepika; De Sauvage, Magali; White, Michael D.; Castro, Brandyn A.; Hoang, Kaitlin; Kaneb, Andrew; Batchelor, Emily D.; Paek, Sun Ha; Park, Sun Hye; Martinez-Lage, Maria; Berghoff, Anna S.; Merrill, Parker; Gerstner, Elizabeth R.; Batchelor, Tracy T.; Frosch, Matthew P.; Frazier, Ryan P.; Borger, Darrell R.; Iafrate, A. John; Johnson, Bruce E.; Santagata, Sandro; Preusser, Matthias; Cahill, Daniel P.; Carter, Scott L.; Brastianos, Priscilla K. Share Save
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Dissecting genomic correlates of response and resistance to chemotherapy in bladder cancer through clinical computational oncology Liu, David; Abbosh, Philip; Keliher, Daniel; Reardon, Brendan; Miao, Diana; Mouw, Kent; Weiner-Taylor, Amaro; Wankowicz, Stephanie; Han, Garam; Teo, Min-Yuen; Cipolla, Catharine; Kim, Jaegil; Iyer, Gopa; Al-Ahmadie, Hikmat; Dulaimi, Essel; Chen, David Y. T.; Alpaugh, R. Katherine; Hoffman-Censits, Jean; Garraway, Levi A.; Getz, Gad; Carter, Scott L.; Bellmunt, Joaquim; Plimack, Elizabeth; Rosenberg, Jonathan E.; Van Allen, Eliezer M. Share Save
Targeting the PI3K/Akt/mTOR pathway with the pan-Akt inhibitor GDC-0068 in PIK3CA-mutant breast cancer brain metastases Ippen, Franziska Maria; Grosch, Julia Katharina; Subramanian, Megha; Kuter, Benjamin Macfarlane; Liederer, Bianca M.; Plise, Emile G.; Mora, Joana Liliana; Nayyar, Naema; Schmidt, Stephen Paul; Giobbie-Hurder, Anita; Martinez-Lage, Maria; Carter, Scott L.; Cahill, Daniel P.; Wakimoto, Hiroaki; Brastianos, Priscilla Kaliopi Share Save
MYD88 L265P mutation and CDKN2A loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas Nayyar, Naema; White, Michael D.; Gill, Corey M.; Lastrapes, Matthew; Bertalan, Mia; Kaplan, Alexander; D'Andrea, Megan R.; Bihun, Ivanna; Kaneb, Andrew; Dietrich, Jorg; Ferry, Judith A.; Martinez-Lage, Maria; Giobbie-Hurder, Anita; Borger, Darrell R.; Rodriguez, Fausto J.; Frosch, Matthew P.; Batchelor, Emily; Hoang, Kaitlin; Kuter, Benjamin; Fortin, Sarah; Holdhoff, Matthias; Cahill, Daniel P.; Carter, Scott; Brastianos, Priscilla K.; Batchelor, Tracy T. Share Save
Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine Aguirre, Andrew J.; Nowak, Jonathan A.; Camarda, Nicholas D.; Moffitt, Richard A.; Ghazani, Arezou A.; Hazar-Rethinam, Mehlika; Raghavan, Srivatsan; Kim, Jaegil; Brais, Lauren K.; Ragon, Dorisanne; Welch, Marisa W.; Reilly, Emma; McCabe, Devin; Marini, Lori; Anderka, Kristin; Helvie, Karla; Oliver, Nelly; Babic, Ana; Da Silva, Annacarolina; Nadres, Brandon; Van Seventer, Emily E.; Shahzade, Heather A.; St Pierre, Joseph P.; Burke, Kelly P.; Clancy, Thomas; Cleary, James M.; Doyle, Leona A.; Jajoo, Kunal; McCleary, Nadine J.; Meyerhardt, Jeffrey A.; Murphy, Janet E.; Ng, Kimmie; Patel, Anuj K.; Perez, Kimberly; Rosenthal, Michael H.; Rubinson, Douglas A.; Ryou, Marvin; Shapiro, Geoffrey I.; Sicinska, Ewa; Silverman, Stuart G.; Nagy, Rebecca J.; Lanman, Richard B.; Knoerzer, Deborah; Welsch, Dean J.; Yurgelun, Matthew B.; Fuchs, Charles S.; Garraway, Levi A.; Getz, Gad; Hornick, Jason L.; Johnson, Bruce E.; Kulke, Matthew H.; Mayer, Robert J.; Miller, Jeffrey W.; Shyn, Paul B.; Tuveson, David A.; Wagle, Nikhil; Yeh, Jen Jen; Hahn, William C.; Corcoran, Ryan B.; Carter, Scott L.; Wolpin, Brian M. Share Save
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