Not logged in Targeting neddylation and sumoylation in chemoresistant triple negative breast cancer Powell, Reid T.; Rinkenbaugh, Amanda L.; Guo, Lei; Cai, Shirong; Shao, Jiansu; Zhou, Xinhui; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Qi, Yuan; Hancock, Faiza Baameur; White, Jason B.; Stephan, Clifford; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen Share Save
PDX models of TNBC established from pre- and post-therapy tumors identify vulnerabilities of resistant disease Rinkenbaugh, Amanda L.; Qi, Yuan; Powell, Reid T.; Cai, Shirong; Shao, Jiansu; Hancock, Faiza Baameur; Guo, Lei; Zhang, Xiaomei; Jeter-Jones, Sabrina; Fu, Chunxiao; Gould, Rebekah; White, Jason B.; Stephan, Clifford; Echeverria, Gloria V.; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen Share Save
Decoding the archetypes and eco-hubs of triple-negative breast cancer in responses to chemotherapy Yan, Yun; Lin, Yiyun; Kumar, Tapsi; Bai, Shanshan; Li, Jianzhuo; Tran, Tuan; Hu, Min; Ravenberg, Elizabeth; Rauch, Maia; Clayborn, Alyson; Thompson, Alastair; Lim, Bora; Huo, Lei; Moulder, Stacy; Yam, Clinton; Navin, Nicholas Share Save
NOS inhibition reverses epithelial-to-mesenchymal transition and synergizes with alpelisib in metaplastic breast cancer Reddy, Tejaswini; Puri, Akshjot; Guzman, Liliana; Qian, Wei; Zhou, Jianying; Rosato, Roberto; Zhao, Hong; Thomas, Christoforos; Li, Xiaoxian; Mahboubi, Bijan; Oo, Adrian; Cho, Young-Jae; Kim, Baek; Thaiparambil, Jose; Ayerbe, Camila; Giese, Noah; Moulder, Stacy; Piwnica-Worms, Helen; Meric-Bernstam, Funda; Chang, Jenny Share Save
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PIK3CA mutations in plasma circulating tumor DNA predict survival and treatment outcomes in patients with advanced cancers Dumbrava, E. E.; Call, S. G.; Huang, H. J.; Stuckett, A. L.; Madwani, K.; Adat, A.; Hong, D. S.; Piha-Paul, S. A.; Subbiah, V.; Karp, D. D.; Fu, S.; Naing, A.; Tsimberidou, A. M.; Moulder, S. L.; Koenig, K. H.; Barcenas, C. H.; Kee, B. K.; Fogelman, D. R.; Kopetz, E. S.; Meric-Bernstam, F.; Janku, F. Share Save
Functional Tumor Volume by Fast Dynamic Contrast-Enhanced MRI for Predicting Neoadjuvant Systemic Therapy Response in Triple-Negative Breast Cancer Musall, Benjamin C.; Abdelhafez, Abeer H.; Adrada, Beatriz E.; Candelaria, Rosalind P.; Mohamed, Rania M. M.; Boge, Medine; Le-Petross, Huong; Arribas, Elsa; Lane, Deanna L.; Spak, David A.; Leung, Jessica W. T.; Hwang, Ken-Pin; Son, Jong Bum; Elshafeey, Nabil A.; Mahmoud, Hagar S.; Wei, Peng; Sun, Jia; Zhang, Shu; White, Jason B.; Ravenberg, Elizabeth E.; Litton, Jennifer K.; Damodaran, Senthil; Thompson, Alastair M.; Moulder, Stacy L.; Yang, Wei T.; Pagel, Mark D.; Rauch, Gaiane M.; Ma, Jingfei Share Save
Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes Gao, Ruli; Bai, Shanshan; Henderson, Ying C.; Lin, Yiyun; Schalck, Aislyn; Yan, Yun; Kumar, Tapsi; Hu, Min; Sei, Emi; Davis, Alexander; Wang, Fang; Shaitelman, Simona F.; Wang, Jennifer Rui; Chen, Ken; Moulder, Stacy; Lai, Stephen Y.; Navin, Nicholas E. Share Save
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Pharmacologic profiling of patient-derived xenograft models of primary treatment-naive triple-negative breast cancer Powell, Reid T.; Redwood, Abena; Liu, Xuan; Guo, Lei; Cai, Shirong; Zhou, Xinhui; Tu, Yizheng; Zhang, Xiaomei; Qi, Yuan; Jiang, Yan; Echeverria, Gloria; Feng, Ningping; Ma, XiaoYan; Giuliani, Virginia; Marszalek, Joseph R.; Heffernan, Timothy P.; Vellano, Christopher P.; White, Jason B.; Stephan, Clifford; Davies, Peter J.; Moulder, Stacy; Symmans, W. Fraser; Chang, Jeffrey T.; Piwnica-Worms, Helen Share Save
The immunomodulatory (IM) signature enhances prediction of pathologic complete response (pCR) to neoadjuvant therapy (NAT) in triple negative breast cancers (TNBC) with moderate stromal tumour infiltrating lymphocytes (sTIL) Abuhadra, N.; Sun, R.; Litton, J. K.; Rauch, G.; Thompson, A. M.; Lim, B.; Adrada, B.; Mittendorf, E.; Damodaran, S.; Pitpitan, R.; Arun, B.; White, J.; Ravenberg, E.; Santiago, L.; Sahin, A.; Murthy, R.; Ueno, N. T.; Ibrahim, N.; Moulder, S.; Huo, L. Share Save
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Serial TILs: Evaluating the role of mid-treatment tumor infiltrating lymphocytes (TIL) in predicting pathologic complete response (pCR) in early-stage triple negative breast cancer (TNBC) Abuhadra, Nour; Hess, Kenneth; Litton, Jennifer; Rauch, Gaiane; Thompson, Alastair; Lim, Bora; Adrada, Beatriz; Mittendorf, Elizabeth; Damodaran, Senthil; Candelaria, Rosalind; Arun, Banu; Yang, Wei Tse; Ueno, Naoto; Santiago, Lumarie; Murthy, Rashmi; Ibrahim, Nuhad; Aysegul, Sahin; Symmans, William; Huo, Lei; Moulder, Stacy Share Save
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Clonal dynamics and phenotypic evolution during chemoresistance and metastasis revealed by patient-derived xenograft models of triple negative breast cancer Echeverria, Gloria V.; Ge, Zhongqi; Seth, Sahil; Powell, Emily; Zhang, Xiaomei; Jeter-Jones, Sabrina; Zhou, Xinhui; Jiang, Yan; McCoy, Aaron; Cai, Shirong; Tu, Yizheng; Peoples, Michael; Sun, Yuting; Qiu, Huan; Bristow, Christopher; Carugo, Alessandro; Shao, Jiansu; Moulder, Stacy L.; Symmans, William F.; Heffernan, Timothy P.; Chang, Jeffrey T.; Piwnica-Worms, Helen M. Share Save
Phase I dose-escalation study of the allosteric AKT inhibitor BAY 1125976 in advanced solid cancer Schneeweiss, Andreas; Hess, Dagmer; Joerger, Markus; Varga, Andrea; Moulder, Stacy; Ma, Cynthia; Krop, Ian; Hurvitz, Sara; Rentzsch, Christine; Rudolph, Marion; Boix, Oliver; Wilkinson, Gary; Lindbom, Lars; Lagkadinou, Eleni; Ocker, Matthias Share Save
Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state Echeverria, Gloria V.; Ge, Zhongqi; Seth, Sahil; Zhang, Xiaomei; Jeter-Jones, Sabrina; Zhou, Xinhui; Cai, Shirong; Tu, Yizheng; McCoy, Aaron; Peoples, Michael; Sun, Yuting; Qiu, Huan; Chang, Qing; Bristow, Christopher; Carugo, Alessandro; Shao, Jiansu; Ma, Xiaoyan; Harris, Angela; Mundi, Prabhjot; Lau, Rosanna; Ramamoorthy, Vandhana; Wu, Yun; Alvarez, Mariano J.; Califano, Andrea; Moulder, Stacy L.; Symmans, William F.; Marszalek, Joseph R.; Heffernan, Timothy P.; Chang, Jeffrey T.; Piwnica-Worms, Helen Share Save
Resistance to neoadjuvant chemotherapy in triple negative breast cancer mediated by a reversible drug-tolerant state Echeverria, G. V.; Ge, Z.; Seth, S.; Jeter-Jones, S. L.; Zhang, X.; Zhou, X.; Cai, S.; Tu, Y.; Mccoy, A.; Peoples, M.; Lau, R.; Shao, J.; Sun, Y.; Bristow, C.; Carugo, A.; Ma, X.; Harris, A.; Wu, Y.; Moulder, S.; Symmans, W. F.; Marszalek, J. R.; Heffernan, T. P.; Chang, J. T.; Piwnica-Worms, H. Share Save
High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer Echeverria, Gloria V.; Powell, Emily; Seth, Sahil; Ge, Zhongqi; Carugo, Alessandro; Bristow, Christopher; Peoples, Michael; Robinson, Frederick; Qiu, Huan; Shao, Jiansu; Jeter-Jones, Sabrina L.; Zhang, Xiaomei; Ramamoorthy, Vandhana; Cai, Shirong; Wu, Wenhui; Draetta, Giulio; Moulder, Stacy L.; Symmans, William F.; Chang, Jeffrey T.; Heffernan, Timothy P.; Piwnica-Worms, Helen Share Save
A phase II study of imatinib mesylate and letrozole in patients with hormone receptor-positive metastatic breast cancer expressing c-kit or PDGFR- Yam, Clinton; Murthy, Rashmi K.; Rauch, Gaiane M.; Murray, James L.; Walters, Ronald S.; Valero, Vicente; Brewster, Abenaa M.; Bast, Robert C., Jr.; Booser, Daniel J.; Giordano, Sharon H.; Esteva, Francisco J.; Yang, Wei; Hortobagyi, Gabriel N.; Moulder, Stacy L.; Arun, Banu Share Save
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