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SaveCancer Organoids as reliable disease models to drive clinical development of novel therapies
Blandino, Giovanni; Satchi-Fainaro, Ronit; Tinhofer, Ingeborg; Tonon, Giovanni; Heilshorn, Sarah C.; Kwon, Yong-Jun; Pestana, Ana; Frascolla, Carlotta; Pompili, Luca; Puce, Aurora; Iachettini, Sara; Tocci, Annalisa; Karkampouna, Sofia; Kruithof-de Julio, Marianna; Tocci, Piera; Porciello, Nicla; Maccaroni, Klizia; Rutigliano, Daniela; Shen, Xiling; Ciliberto, Gennaro Share Save Proteome-wide Mendelian randomization and functional studies uncover therapeutic targets for polycystic ovarian syndromeNi, Feida; Wang, Feixia; Sun, Jing; Tu, Mixue; Chen, Jianpeng; Shen, Xiling; Ye, Xiaohang; Chen, Ruixue; Liu, Yifeng; Sun, Xiao; Chen, Jianhua; Li, Xue; Zhang, Dan Share Save Share Save Longitudinal intravital imaging of mouse placentaZhu, Xiaoyi; Huang, Qiang; Jiang, Laiming; Nguyen, Van-Tu; Vu, Tri; Devlin, Garth; Shaima, Jabbar; Wang, Xiaobei; Chen, Yong; Ma, Lijun; Xiang, Kun; Wang, Ergang; Rong, Qiangzhou; Zhou, Qifa; Kang, Yubin; Asokan, Aravind; Feng, Liping; Hsu, Shiao-Wen D.; Shen, Xiling; Yao, Junjie Share Save Patient-Derived Organoids as Therapy Screening Platforms in Cancer PatientsKhorsandi, Danial; Yang, Jia-Wei; Foster, Samuel; Khosravi, Safoora; Hosseinzadeh Kouchehbaghi, Negar; Zarei, Fahimeh; Lee, Yun Bin; Runa, Farhana; Gangrade, Ankit; Voskanian, Leon; Adnan, Darbaz; Zhu, Yangzhi; Wang, Zhaohui; Jucaud, Vadim; Dokmeci, Mehmet Remzi; Shen, Xiling; Bishehsari, Faraz; Kelber, Jonathan A.; Khademhosseini, Ali; de Barros, Natan Roberto Share Save Chromatin Remodeling in Patient-Derived Colorectal Cancer ModelsXiang, Kun; Wang, Ergang; Mantyh, John; Rupprecht, Gabrielle; Negrete, Marcos; Sanati, Golshid; Hsu, Carolyn; Randon, Peggy; Dohlman, Anders; Kretzschmar, Kai; Bose, Shree; Giroux, Nicholas; Ding, Shengli; Wang, Lihua; Balcazar, Jorge Prado; Huang, Qiang; Sundaramoorthy, Pasupathi; Xi, Rui; Mccall, Shannon Jones; Wang, Zhaohui; Jiang, Chongming; Kang, Yubin; Kopetz, Scott; Crawford, Gregory E.; Lipkin, Steven M.; Wang, Xiao-Fan; Clevers, Hans; Hsu, David; Shen, Xiling Share Save Share Save Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion (vol 12, 11714, 2022)Giroux, Nicholas S.; Ding, Shengli; McClain, Micah T.; Burke, Thomas W.; Petzold, Elizabeth; Chung, Hong A.; Rivera, Grecia O.; Wang, Ergang; Xi, Rui; Bose, Shree; Rotstein, Tomer; Nicholson, Bradly P.; Chen, Tianyi; Henao, Ricardo; Sempowski, Gregory D.; Denny, Thomas N.; De Ussel, Maria Iglesias; Satterwhite, Lisa L.; Ko, Emily R.; Ginsburg, Geoffrey S.; Kraft, Bryan D.; Tsalik, Ephraim L.; Shen, Xiling; Woods, Christopher W. Share Save Share Save Patient-derived MicroOrganoSpheres (MOS) enable precision clinical decision-making for multiple myeloma patientsXi, Rui; Wang, Xiaobei; Moseley, Robert; Raman, Renuka; Zhang, Ray; Jaibbar, Shaima; Steele, Shaun; Ding, Shengi; Kang, Yubing; Shen, Xiling Share Save Evaluating targeted therapy combination for refractory colorectal cancer using MicroOrganoSpheres (MOS)Ding, Shengli; Marie, Preeti Kanikarla; Zhang, Ray; Bohn, Alan; Moseley, Robert Moseley; Baro, Nicholas; Brown, Dan; Pittman, Kelly; Paduch, Marcin; Hsu, David; Kopetz, Scott; Shen, Xiling Share Save Share Save Share Save Thioredoxin-1 regulates self-renewal and differentiation of murine hematopoietic stem cells through p53 tumor suppressorJabbar, Shaima; Mathews, Parker; Wang, Xiaobei; Sundaramoorthy, Pasupathi; Chu, Emily; Piryani, Sadhna O.; Ding, Shengli; Shen, Xiling; Doan, Phuong L.; Kang, Yubin Share Save Share Save Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT)Li, Mucong; Beaumont, Nathan; Ma, Chenshuo; Rojas, Juan; Vu, Tri; Harlacher, Max; O'Connell, Graeme; Gessner, Ryan C.; Kilian, Hailey; Kasatkina, Ludmila; Chen, Yong; Huang, Qiang; Shen, Xiling; Lovell, Jonathan F.; Verkhusha, Vladislav V.; Czernuszewicz, Tomek; Yao, Junjie Share Save Rapid tissue prototyping with micro-organospheres brWang, Zhaohui; Boretto, Matteo; Millen, Rosemary; Natesh, Naveen; Reckzeh, Elena S.; Hsu, Carolyn; Negrete, Marcos; Yao, Haipei; Quayle, William; Heaton, Brook E.; Harding, Alfred T.; Bose, Shree; Driehuis, Else; Beumer, Joep; Rivera, Grecia O.; van Ineveld, Ravian L.; Gex, Donald; DeVilla, Jessica; Wang, Daisong; Puschhof, Jens; Geurts, Maarten H.; Yeung, Athena; Hamele, Cait; Smith, Amber; Bankaitis, Eric; Xiang, Kun; Ding, Shengli; Nelson, Daniel; Delubac, Daniel; Rios, Anne; Abi-Hachem, Ralph; Jang, David; Goldstein, Bradley J.; Glass, Carolyn; Heaton, Nicholas S.; Hsu, David; Clevers, Hans; Shen, Xiling Share Save Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversionGiroux, Nicholas S.; Ding, Shengli; McClain, Micah T.; Burke, Thomas W.; Petzold, Elizabeth; Chung, Hong A.; Rivera, Grecia O.; Wang, Ergang; Xi, Rui; Bose, Shree; Rotstein, Tomer; Nicholson, Bradly P.; Chen, Tianyi; Henao, Ricardo; Sempowski, Gregory D.; Denny, Thomas N.; De Ussel, Maria Iglesias; Satterwhite, Lisa L.; Ko, Emily R.; Ginsburg, Geoffrey S.; Kraft, Bryan D.; Tsalik, Ephraim L.; Shen, Xiling; Woods, Christopher W. 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