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Proteomic signatures of Alzheimer's disease and Lewy body dementias: A comparative analysis Canal-Garcia, Anna; Branca, Rui M.; Francis, Paul T.; Ballard, Clive; Winblad, Bengt; Lehtio, Janne; Nilsson, Per; Aarsland, Dag; Pereira, Joana B.; Bereczki, Erika Share Save
A pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer's disease and agitated behaviours: the HTA-SYMBAD trial Banerjee, Sube; Farina, Nicolas; Henderson, Catherine; High, Juliet; Stirling, Susan; Shepstone, Lee; Fountain, Julia; Ballard, Clive; Bentham, Peter; Burns, Alistair; Fox, Chris; Francis, Paul; Howard, Robert; Knapp, Martin; Leroi, Iracema; Livingston, Gill; Nilforooshan, Ramin; Nurock, Shirley; O'Brien, John; Price, Annabel; Thomas, Alan J.; Swart, Ann Marie; Telling, Tanya; Tabet, Naji Share Save
Decreased DHA-containing phospholipids in the neocortex of dementia with Lewy bodies are associated with soluble Aβ42, phosphorylated α-synuclein, and synaptopathology Chong, Joyce R. R.; Chai, Yuek Ling; Xing, Huayang; Herr, Deron R.; Wenk, Markus R.; Francis, Paul T.; Ballard, Clive; Aarsland, Dag; Silver, David L.; Chen, Christopher P. P.; Cazenave-Gassiot, Amaury; Lai, Mitchell K. P. Share Save
Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias Chai, Yuek Ling; Lee, Jasinda H. H.; Chong, Joyce R. R.; Ballard, Clive; Francis, Paul T.; Kennedy, Brian K.; Arumugam, Thiruma V.; Chen, Christopher P. P.; Aarsland, Dag; Lai, Mitchell K. P. Share Save
DNA methylation signatures of Alzheimer's disease neuropathology in the cortex are primarily driven by variation in non-neuronal cell-types Shireby, Gemma; Dempster, Emma L.; Policicchio, Stefania; Smith, Rebecca G.; Pishva, Ehsan; Chioza, Barry; Davies, Jonathan P.; Burrage, Joe; Lunnon, Katie; Vellame, Dorothea Seiler; Love, Seth; Thomas, Alan; Brookes, Keeley; Morgan, Kevin; Francis, Paul; Hannon, Eilis; Mill, Jonathan Share Save
Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology Pihlstrom, Lasse; Shireby, Gemma; Geut, Hanneke; Henriksen, Sandra Pilar; Rozemuller, Annemieke J. M.; Tunold, Jon-Anders; Hannon, Eilis; Francis, Paul; Thomas, Alan J.; Love, Seth; Mill, Jonathan; van de Berg, Wilma D. J.; Toft, Mathias Share Save
Relevance of sleep and associated structural changes in GBA1 mouse to human rapid eye movement behavior disorder Gelegen, Cigdem; Cash, Diana; Ilic, Katarina; Sander, Millie; Kim, Eugene; Simmons, Camilla; Bernanos, Michel; Lama, Joana; Randall, Karen; Brown, Jonathan T.; Kalanj-Bognar, Svjetlana; Cooke, Samuel; Chaudhuri, K. Ray; Ballard, Clive; Francis, Paul; Rosenzweig, Ivana Share Save
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex Smith, Rebecca G.; Pishva, Ehsan; Shireby, Gemma; Smith, Adam R.; Roubroeks, Janou A. Y.; Hannon, Eilis; Wheildon, Gregory; Mastroeni, Diego; Gasparoni, Gilles; Riemenschneider, Matthias; Giese, Armin; Sharp, Andrew J.; Schalkwyk, Leonard; Haroutunian, Vahram; Viechtbauer, Wolfgang; van den Hove, Daniel L. A.; Weedon, Michael; Brokaw, Danielle; Francis, Paul T.; Thomas, Alan J.; Love, Seth; Morgan, Kevin; Walter, Joern; Coleman, Paul D.; Bennett, David A.; De Jager, Philip L.; Mill, Jonathan; Lunnon, Katie Share Save
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Genetic variants in glutamate-, Aβ-, and tau-related pathways determine polygenic risk for Alzheimer's disease Lawingco, Ted; Chaudhury, Sultan; Brookes, Keeley J.; Guetta-Baranes, Tamar; Guerreiro, Rita; Bras, Jose; Hardy, John; Francis, Paul; Thomas, Alan; Belbin, Olivia; Morgan, Kevin Share Save
Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementia McAleese, Kirsty E.; Colloby, Sean J.; Thomas, Alan J.; Al-Sarraj, Safa; Ansorge, Olaf; Neal, James; Roncaroli, Federico; Love, Seth; Francis, Paul T.; Attems, Johannes Share Save
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Striatal Dopaminergic Deficit and Sleep in Idiopathic Rapid Eye Movement Behaviour Disorder: An Explorative Study Wasserman, Danielle; Bindman, Dorothea; Nesbitt, Alexander D.; Cash, Diana; Milosevic, Milan; Francis, Paul T.; Chaudhuri, K. Ray; Leschziner, Guy D.; Ferini-Strambi, Luigi; Ballard, Clive; Eccles, Amy; Rosenzweig, Ivana Share Save
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Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex Shireby, Gemma L.; Davies, Jonathan P.; Francis, Paul T.; Burrage, Joe; Walker, Emma M.; Neilson, Grant W. A.; Dahir, Aisha; Thomas, Alan J.; Love, Seth; Smith, Rebecca G.; Lunnon, Katie; Kumari, Meena; Schalkwyk, Leonard C.; Morgan, Kevin; Brookes, Keeley; Hannon, Eilis; Mill, Jonathan Share Save
Genetic risk for Alzheimer's disease influences neuropathology via multiple biological pathways Hannon, Eilis; Shireby, Gemma L.; Brookes, Keeley; Attems, Johannes; Sims, Rebecca; Cairns, Nigel J.; Love, Seth; Thomas, Alan J.; Morgan, Kevin; Francis, Paul T.; Mill, Jonathan Share Save