Congyi Lu - Publications, H-index & Citations

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Congyi Lu

Broad Institute

23H-index

58Paper Count

2.4KCitation Count

Published Papers 29

Publication Date

Publisher Correction: CRISPR activation for SCN2A-related neurodevelopmental disorders

Nature

IF48.5

2025-12-08

OAAI

Serena Tamura; Andrew D. Nelson; Perry W. E. Spratt; Elizabeth C. Hamada; Xujia Zhou; Henry Kyoung; Zizheng Li; Coline Arnould; Vladyslav Barskyi; Beniamin Krupkin; Kiana Young; Jingjing Zhao; Stephanie S. Holden; Atehsa Sahagun; Caroline M. Keeshen; Congyi Lu; Roy Ben-Shalom; Sunrae E. Taloma; Selin Schamiloglu; Ying C. Li; Lia Min; Paul M. Jenkins; Jen Q. Pan; Jeanne T. Paz; Stephan J. Sanders; Navneet Matharu; Nadav Ahituv; Kevin J. Bender

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CRISPR activation for SCN2A-related neurodevelopmental disorders

Nature

IF48.5

2025-09-17

PREAI

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Targeted CRISPR approach reveals an essential role for neuropeptide Y receptor Y5 in Ewing sarcoma extrapulmonary metastasis

Oncogene

IF7.3

2025-07-17

PREAI

Mina Adnani; Sung-Hyeok Hong; Susana Galli; Akanksha Mahajan; Congyi Lu; Nouran Abualsaud; Tyler Biermann; Yiwen Li; Andrea Rivera; Bethel S. Sebsebie; Lindsay Caprio; Lindsey Kuwahara; Ewa Krawczyk; Jason U. Tilan; Yichen Lee; Olga Rodriguez; Hongkun Wang; Lu Jin; Maureen Regan; Sonia de Assis; Christopher Albanese; Svetlana D. Pack; Luciane R. Cavalli; Joanna Kitlinska

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Essential transcription factors for induced neuron differentiation

NATURE COMMUNICATIONS

IF15.7

2023-12-15

OAAI

Lu, Congyi; Garipler, Gorkem; Dai, Chao; Roush, Timothy; Salome-Correa, Jose; Martin, Alex; Liscovitch-Brauer, Noa; Mazzoni, Esteban O.; Sanjana, Neville E.

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Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2023-10-01

OAAI

Shi, Xi; Lu, Congyi; Corman, Alba; Nikish, Alexandra; Zhou, Yang; Platt, Randy J.; Iossifov, Ivan; Zhang, Feng; Pan, Jen Q.; Sanjana, Neville E.

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Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma (vol 13, 2323, 2022)

NATURE COMMUNICATIONS

IF15.7

2022-05-12

OAAI

Lu, Congyi; Mahajan, Akanksha; Hong, Sung-Hyeok; Galli, Susana; Zhu, Shiya; Tilan, Jason U.; Abualsaud, Nouran; Adnani, Mina; Chung, Stacey; Elmansy, Nada; Rodgers, Jasmine; Rodriguez, Olga; Albanese, Christopher; Wang, Hongkun; Regan, Maureen; Zgonc, Valerie; Blancato, Jan; Krawczyk, Ewa; Gallicano, G. Ian; Girgis, Michael; Cheema, Amrita; Izycka-Swieszewska, Ewa; Cavalli, Luciane R.; Pack, Svetlana D.; Kitlinska, Joanna

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Hypoxia-activated neuropeptide Y/Y5 receptor/RhoA pathway triggers chromosomal instability and bone metastasis in Ewing sarcoma

NATURE COMMUNICATIONS

IF15.7

2022-04-28

OAAI

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The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes

CELL REPORTS

IF6.9

2022-03-01

OAAI

Garipler, Gorkem; Lu, Congyi; Morrissey, Alexis; Lopez-Zepeda, Lorena S.; Pei, Yingzhen; Vidal, Simon E.; Fiore, Ana Paula Zen Petisco; Aydin, Begum; Stadtfeld, Matthias; Ohler, Uwe; Mahony, Shaun; Sanjana, Neville E.; Mazzoni, Esteban O.

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Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

GENOME BIOLOGY

IF9.4

2021-03-04

OAAI

Sorek, Matan; Oweis, Walaa; Nissim-Rafinia, Malka; Maman, Moria; Simon, Shahar; Hession, Cynthia C.; Adiconis, Xian; Simmons, Sean K.; Sanjana, Neville E.; Shi, Xi; Lu, Congyi; Pan, Jen Q.; Xu, Xiaohong; Pouladi, Mahmoud A.; Ellerby, Lisa M.; Zhang, Feng; Levin, Joshua Z.; Meshorer, Eran

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Hypoxia-induced phenotypic and metabolic changes in Ewing sarcoma cells trigger bone metastasis

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Zhu, Shiya; Mahajan, Akanksha; Hong, Sung-Hyeok; Galli, Susana; Lu, Congyi; Chen, You-Shin; Misiukiewicz, Sara; Chung, Stacey; Tilan, Jason; Kitlinska, Joanna B.

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Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons

FASEB JOURNAL

IF4.2

2019-01-30

OAAI

Lu, Congyi; Shi, Xi; Allen, Andrew; Baez-Nieto, David; Nikish, Alexandria; Sanjana, Neville E.; Pan, Jen Q.

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The role of neuropeptide Y and its Y5 receptor in RhoA-mediated regulation of cytokinesis and cell motility

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Abualsaud, Nouran; Lu, Congyi; Mahajan, Akanksha; Bakr, Abrar; Zhu, Shiya; Caprio, Lindsay; Hong, Sung Hyeok; Kitlinska, Joanna

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Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

NATURE BIOMEDICAL ENGINEERING

IF26.6

2018-04-09

OAAI

Tekin, Halil; Simmons, Sean; Cummings, Beryl; Gao, Linyi; Adiconis, Xian; Hession, Cynthia C.; Ghoshal, Ayan; Dionne, Danielle; Choudhury, Sourav R.; Yesilyurt, Volkan; Sanjana, Neville E.; Shi, Xi; Lu, Congyi; Heidenreich, Matthias; Pan, Jen Q.; Levin, Joshua Z.; Zhang, Feng

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Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2017-04-17

126

OAAI

Wang, Wenting; Li, Chenchen; Chen, Qian; van der Goes, Marie-Sophie; Hawrot, James; Yao, Annie Y.; Gao, Xian; Lu, Congyi; Zang, Ying; Zhang, Qiangge; Lyman, Katherine; Wang, Dongqing; Guo, Baolin; Wu, Shengxi; Gerfen, Charles R.; Fu, Zhanyan; Feng, Guoping

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Ewing sarcoma progression associates with increasing chromosomal instability: A role for neuropeptide Y and its Y5 receptor

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

Mahajan, Akanksha; Hong, Sung-Hyeok; Than, Jason U.; Galli, Susana; Lu, Congyi; Rodgers, Jasmine; Duttargi, Anju; Acree, Rachel; Cavalli, Luciane R.; Kitlinska, Joanna B.

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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

NEURON

IF15

2016-01-01

267

OAAI

Zhou, Yang; Kaiser, Tobias; Monteiro, Patricia; Zhang, Xiangyu; Van der Goes, Marie. S.; Wang, Dongqing; Barak, Boaz; Zeng, Menglong; Li, Chenchen; Lu, Congyi; Wells, Michael; Amaya, Aldo; Shannon Nguyen; Lewis, Michael; Sanjana, Neville; Zhou, Yongdi; Zhang, Mingjie; Zhang, Feng; Fu, Zhanyan; Feng, Guoping

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Micro-electrode array recordings reveal reductions in both excitation and inhibition in cultured cortical neuron networks lacking Shank3

MOLECULAR PSYCHIATRY

IF10.1

2015-11-24

OAAI

Lu, C.; Chen, Q.; Zhou, T.; Bozic, D.; Fu, Z.; Pan, J. Q.; Feng, G.

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Systemic Levels of Neuropeptide Y and Dipeptidyl Peptidase Activity in Patients With Ewing Sarcoma-Associations With Tumor Phenotype and Survival

CANCER

IF5.1

2014-11-11

OAAI

Tilan, Jason U.; Krailo, Mark; Barkauskas, Donald A.; Galli, Susana; Mtaweh, Haifa; Long, Jessica; Wang, Hongkun; Hawkins, Kirsten; Lu, Congyi; Jeha, Dima; Izycka-Swieszewska, Ewa; Lawlor, Elizabeth R.; Toretsky, Jeffrey A.; Kitlinska, Joanna B.

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Neuropeptide Y Y5 receptor in neuroblastoma chemoresistance

CANCER RESEARCH

IF16.6

2014-10-01

PREAI

Trinh, Emily; Czarnecka, Magdalena; Hong, Sung-Hyeok; Lu, Congyi; Martin, Samantha; Galli, Susana; Izycka-Swieszewska, Ewa; Kuan-Celarier, Anna; Christian, David; Horton, Meredith; Tilan, Jason U.; Kitlinska, Joanna B.

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Neuropeptide Y receptor Y5 as an inducible pro-survival factor in neuroblastoma: implications for tumor chemoresistance

ONCOGENE

IF7.3

2014-08-18

OAAI

Czarnecka, M.; Trinh, E.; Lu, C.; Kuan-Celarier, A.; Galli, S.; Hong, S-H; Tilan, J. U.; Talisman, N.; Izycka-Swieszewska, E.; Tsuei, J.; Yang, C.; Martin, S.; Horton, M.; Christian, D.; Everhart, L.; Maheswaran, I.; Kitlinska, J.

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Research Directions