Matthijs K. C. Hesselink - Publications, H-index & Citations

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Matthijs K. C. Hesselink

Maastricht University

72H-index

270Paper Count

1.7WCitation Count

Published Papers 152

Publication Date

ATGL-mediated lipolysis is essential for myocellular mitochondrial function, mitochondria-lipid droplet interaction and mitochondrial network connectivity

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

IF0

2025-11-10

PREAI

Anne Gemmink; Tineke van de Weijer; Gert Schaart; Gernot F. Grabner; Esther Kornips; Kèvin Knoops; Rudolf Zechner; Martina Schweiger; Matthijs K.C. Hesselink

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Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes

DIABETES OBESITY & METABOLISM

IF5.7

2025-02-01

OAAI

op den Kamp-bruls, Yvonne M. H.; op den Kamp, Yvo J. M.; Veeraiah, Pandichelvam; Perez, Ruben Zapata; Phielix, Esther; Havekes, Bas; Schaart, Gert; Kornips, Esther; Berendsen, Bart R. B.; Virmani, Ashraf; Wildberger, Joachim E.; Houtkooper, Riekelt H.; Hesselink, Matthijs K. C.; Schrauwen, Patrick; Schrauwen-Hinderling, Vera B.

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Development of a 31P magnetic resonance spectroscopy technique to quantify NADH and NAD+ at 3 T

NATURE COMMUNICATIONS

IF15.7

2024-10-24

OAAI

Mevenkamp, Julian; Bruls, Yvonne M. H.; Mancilla, Rodrigo; Grevendonk, Lotte; Wildberger, Joachim E.; Brouwers, Kim; Hesselink, Matthijs K. C.; Schrauwen, Patrick; Hoeks, Joris; Houtkooper, Riekelt H.; Buitinga, Mijke; de Graaf, Robin A.; Lindeboom, Lucas; Schrauwen-Hinderling, Vera B.

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Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2

BASIC RESEARCH IN CARDIOLOGY

IF8

2024-07-24

OAAI

Chen, Sha; Wang, Qian; Bakker, Diane; Hu, Xin; Zhang, Liping; van der Made, Ingeborg; Tebbens, Anna M.; Kovacshazi, Csenger; Giricz, Zoltan; Brenner, Gabor B.; Ferdinandy, Peter; Schaart, Gert; Gemmink, Anne; Hesselink, Matthijs K. C.; Rivaud, Mathilde R.; Pieper, Michael P.; Hollmann, Markus W.; Weber, Nina C.; Balligand, Jean-Luc; Creemers, Esther E.; Coronel, Ruben; Zuurbier, Coert J.

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The impact of prolonged fasting on 24h energy metabolism and its 24h rhythmicity in healthy, lean males: A randomized cross-over trial

CLINICAL NUTRITION

IF7.4

2023-12-01

OAAI

Andriessen, Charlotte; Doligkeit, Daniel; Moonen-Kornips, Esther; Mensink, Marco; Hesselink, Matthijs K. C.; Hoeks, Joris; Schrauwen, Patrick

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The tissue-specific metabolic effects of the PPARa agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study

OBESITY

IF4.7

2023-09-05

OAAI

de Wit-Verheggen, Vera H. W.; Vanweert, Froukje; Raiko, Juho; Lienard, Viktor; Schaart, Gert; Gemmink, Anne; Nascimento, Emmani B. M.; Hesselink, Matthijs K. C.; Wildberger, Joachim E.; Wierts, Roel; Joris, Peter J.; Haas, Joel; Montaigne, David; Staels, Bart; Phielix, Esther; Schrauwen, Patrick; Schrauwen-Hinderling, Vera B.; van de Weijer, Tineke

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Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity

MOLECULAR METABOLISM

IF6.6

2023-06-01

OAAI

Gemmink, Anne; Daemen, Sabine; Wefers, Jakob; Hansen, Jan; van Moorsel, Dirk; Astuti, Puji; Jorgensen, Johanna A.; Kornips, Esther; Schaart, Gert; Hoeks, Joris; Schrauwen, Patrick; Hesselink, Matthijs K. C.

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PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans

SCIENTIFIC REPORTS

IF3.9

2023-05-23

OAAI

de Wit-Verheggen, Vera H. W.; Schrauwen-Hinderling, Vera B.; Brouwers, Kim; Joergensen, Johanna A.; Schaart, Gert; Gemmink, Anne; Nascimento, Emmani B. M.; Hesselink, Matthijs K. C.; Wildberger, Joachim E.; Segers, Patrique; Montaigne, David; Staels, Bart; Schrauwen, Patrick; Lindeboom, Lucas; Hoeks, Joris; van de Weijer, Tineke

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Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial

NATURE COMMUNICATIONS

IF15.7

2023-01-12

OAAI

van Beek, Sten M. M.; Bruls, Yvonne M. H.; Vanweert, Froukje; Fealy, Ciaran E.; Connell, Niels J. J.; Schaart, Gert; Moonen-Kornips, Esther; Jorgensen, Johanna A. A.; Vaz, Frederic M.; Smeets, Ellen T. H. C.; Joris, Peter J. J.; Gemmink, Anne; Houtkooper, Riekelt H. H.; Hesselink, Matthijs K. C.; Bengtsson, Tore; Havekes, Bas; Schrauwen, Patrick; Hoeks, Joris

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Skeletal muscle mitochondrial inertia is associated with carnitine acetyltransferase activity and physical function in humans

JCI INSIGHT

IF6.1

2023-01-10

OAAI

Mancilla, Rodrigo F.; Lindeboom, Lucas; Grevendonk, Lotte; Hoeks, Joris; Koves, Tim R.; Muoio, Deborah M.; Schrauwen, Patrick; Schrauwen-Hinderling, Vera; Hesselink, Matthijs K. C.

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Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men

CELL REPORTS

IF6.9

2022-12-01

OAAI

Harmsen, Jan-Frieder; van Weeghel, Michel; Parsons, Rex; Janssens, Georges E.; Wefers, Jakob; van Moorsel, Dirk; Hansen, Jan; Hoeks, Joris; Hesselink, Matthijs K. C.; Houtkooper, Riekelt H.; Schrauwen, Patrick

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Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism

MOLECULAR METABOLISM

IF6.6

2022-12-01

OAAI

op den Kamp, Yvo J. M.; Gemmink, Anne; de Ligt, Marlies; Dautzenberg, Bas; Kornips, Esther; Jorgensen, Johanna A.; Schaart, Gert; Esterline, Russell; Pava, Diego A.; Hoeks, Joris; Schrauwen-Hinderling, Vera B.; Kersten, Sander; Havekes, Bas; Koves, Timothy R.; Muoio, Deborah M.; Hesselink, Matthijs K. C.; Oscarsson, Jan; Phielix, Esther; Schrauwen, Patrick

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Timing of physical activity in relation to liver fat content and insulin resistance

DIABETOLOGIA

IF10.2

2022-11-01

OAAI

van der Velde, Jeroen H. P. M.; Boone, Sebastiaan C.; Winters-van Eekelen, Esther; Hesselink, Matthijs K. C.; Schrauwen-Hinderling, Vera B.; Schrauwen, Patrick; Lamb, Hildo J.; Rosendaal, Frits R.; de Mutsert, Renee

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Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary

GEROSCIENCE

IF5.4

2022-10-15

OAAI

Erickson, Melissa L.; Allen, Jacob M.; Beavers, Daniel P.; Collins, Linda M.; Davidson, Karina W.; Erickson, Kirk, I; Esser, Karyn A.; Hesselink, Matthijs K. C.; Moreau, Kerrie L.; Laber, Eric B.; Peterson, Charlotte A.; Peterson, Courtney M.; Reusch, Jane E.; Thyfault, John P.; Youngstedt, Shawn D.; Zierath, Juleen R.; Goodpaster, Bret H.; LeBrasseur, Nathan K.; Buford, Thomas W.; Sparks, Lauren M.

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Differences in Performance Assessments Conducted Indoors and Outdoors in Professional Cyclists

INTERNATIONAL JOURNAL OF SPORTS PHYSIOLOGY AND PERFORMANCE

IF4.3

2022-07-01

OAAI

Lipski, Elliot S.; Spindler, David J.; Hesselink, Matthijs K. C.; Myers, Tony D.; Sanders, Dajo

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

NATURE COMMUNICATIONS

IF15.7

2022-06-18

OAAI

Vanweert, Froukje; Neinast, Michael; Tapia, Edmundo Erazo; van de Weijer, Tineke; Hoeks, Joris; Schrauwen-Hinderling, Vera B.; Blair, Megan C.; Bornstein, Marc R.; Hesselink, Matthijs K. C.; Schrauwen, Patrick; Arany, Zoltan; Phielix, Esther

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Effects of the SGLT2 Inhibitor Dapagliflozin on Energy Metabolism in Patients With Type 2 Diabetes: A Randomized, Double-Blind Crossover Trial (vol 44, pg 1334, 2021)

DIABETES CARE

IF16.6

2022-03-03

OAAI

den Kamp, Yvo J. M. Op; de Ligt, Marlies; Dautzenberg, Bas; Kornips, Esther; Esterline, Russell; Hesselink, Matthijs K. C.; Hoeks, Joris; Schrauwen-Hinderling, Vera B.; Havekes, Bas; Oscarsson, Jan; Phielix, Esther; Schrauwen, Patrick

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Genomics and transcriptomics landscapes associated to changes in insulin sensitivity in response to endurance exercise training

SCIENTIFIC REPORTS

IF3.9

2021-12-02

OAAI

Takeshita, Louise Y.; Davidsen, Peter K.; Herbert, John M.; Antczak, Philipp; Hesselink, Matthijs K. C.; Schrauwen, Patrick; Weisnagel, S. John; Robbins, Jeremy M.; Gerszten, Robert E.; Ghosh, Sujoy; Sarzynski, Mark A.; Bouchard, Claude; Falciani, Francesco

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Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Trends in Molecular Medicine

IF13.8

2021-11-01

OAAI

Fealy, Ciaran E.; Grevendonk, Lotte; Hoeks, Joris; Hesselink, Matthijs K. C.

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Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women

DIABETOLOGIA

IF10.2

2021-09-12

OAAI

Remie, Carlijn M. E.; Janssens, Georges E.; Bilet, Lena; van Weeghel, Michel; Duvivier, Bernard M. F. M.; de Wit, Vera H. W.; Connell, Niels J.; Jorgensen, Johanna A.; Schomakers, Bauke, V; Schrauwen-Hinderling, Vera B.; Hoeks, Joris; Hesselink, Matthijs K. C.; Phielix, Esther; Houtkooper, Riekelt H.; Schrauwen, Patrick

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Research Directions