Not logged in A melanocyte lineage program confers resistance to MAP kinase pathway inhibition Johannessen, Cory M.; Johnson, Laura A.; Piccioni, Federica; Townes, Aisha; Frederick, Dennie T.; Donahue, Melanie K.; Narayan, Rajiv; Flaherty, Keith T.; Wargo, Jennifer A.; Root, David E.; Garraway, Levi A. Share Save
Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView (OCT, 10.1038/s41587-024-02391-0, 2024) Kudo, Takamasa; Meireles, Ana M.; Moncada, Reuben; Chen, Yushu; Wu, Ping; Gould, Joshua; Hu, Xiaoyu; Kornfeld, Opher; Jesudason, Rajiv; Foo, Conrad; Hockendorf, Burkhard; Corrada Bravo, Hector; Town, Jason P.; Wei, Runmin; Rios, Antonio; Chandrasekar, Vineethkrishna; Heinlein, Melanie; Chuong, Amy S.; Cai, Shuangyi; Lu, Cherry Sakura; Coelho, Paula; Mis, Monika; Celen, Cemre; Kljavin, Noelyn; Jiang, Jian; Richmond, David; Thakore, Pratiksha; Benito-Gutierrez, Elia; Geiger-Schuller, Kathryn; Hleap, Jose Sergio; Kayagaki, Nobuhiko; Melo, Felipe; Mcginnis, Lisa; Li, Bo; Singh, Avtar; Garraway, Levi; Rozenblatt-Rosen, Orit; Regev, Aviv; Lubeck, Eric Share Save
Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView Kudo, Takamasa; Meireles, Ana M.; Moncada, Reuben; Chen, Yushu; Wu, Ping; Gould, Joshua; Hu, Xiaoyu; Kornfeld, Opher; Jesudason, Rajiv; Foo, Conrad; Hockendorf, Burkhard; Bravo, Hector Corrada; Town, Jason P.; Wei, Runmin; Rios, Antonio; Chandrasekar, Vineethkrishna; Heinlein, Melanie; Chuong, Amy S.; Cai, Shuangyi; Lu, Cherry Sakura; Coelho, Paula; Mis, Monika; Celen, Cemre; Kljavin, Noelyn; Jiang, Jian; Richmond, David; Thakore, Pratiksha; Benito-Gutierrez, Elia; Geiger-Schuller, Kathryn; Hleap, Jose Sergio; Kayagaki, Nobuhiko; Melo, Felipe; McGinnis, Lisa; Li, Bo; Singh, Avtar; Garraway, Levi; Rozenblatt-Rosen, Orit; Regev, Aviv; Lubeck, Eric Share Save
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Persistent patient barriers to genomic testing in ambulatory oncology Haakenstad, Ellana K.; Roberts, Jane; Revette, Anna C.; Loeser, Wendy; Grider, Joseph; Kruse, Andrea; Gentile, Alissa; Freedman, Rachel; Lindeman, Neal I.; Kozyreva, Olga; Sanz-Altamira, Pedro; Lathan, Christopher S.; Hassett, Michael; Cerami, Ethan; Kim, Annette S.; Manning, Danielle K.; Nowak, Jonathan; Giannakis, Marios; Lindsley, R. Coleman; Hahn, William C.; Rollins, Barrett J.; Garraway, Levi; Johnson, Bruce E.; McCleary, Nadine Jackson Share Save
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REAL variance in genomic testing by sex, age, race, ethnicity, and language: PROFILE database 7/2011-1/2022 McCleary, Nadine Jackson; Haakenstad, Ellana K.; Neville, Bridget; Bertram, Arrien A.; Loeser, Wendy; Grider, Joseph; Kruse, Andea; Gentile, Alissa; Kozyreva, Olga; Sanz-Altamira, Pedro; Lathan, Christopher; Hassett, Michael J.; Cerami, Ethan; Kim, Annette S.; Giannakis, Marios; Lindsley, R. Coleman; Lindeman, Neal I.; Hahn, William C.; Longtine, Janina; Rollins, Barrett; Garraway, Levi; Johnson, Bruce E. Share Save
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Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses Lo, Jennifer A.; Kawakubo, Masayoshi; Juneja, Vikram R.; Su, Mack Y.; Erlich, Tal H.; LaFleur, Martin W.; Kemeny, Lajos, V; Rashid, Mamunur; Malehmir, Mohsen; Rabi, S. Alireza; Raghavan, Rumya; Allouche, Jennifer; Kasumova, Gyulnara; Frederick, Dennie T.; Pauken, Kristen E.; Weng, Qing Yu; da Silva, Marcelo Pereira; Xu, Yu; van der Sande, Anita A. J.; Silkworth, Whitney; Roider, Elisabeth; Browne, Edward P.; Lieb, David J.; Wang, Belinda; Garraway, Levi A.; Wu, Catherine J.; Flaherty, Keith T.; Brinckerhoff, Constance E.; Mullins, David W.; Adams, David J.; Hacohen, Nir; Hoang, Mai P.; Boland, Genevieve M.; Freeman, Gordon J.; Sharpe, Arlene H.; Manstein, Dieter; Fisher, David E. Share Save
Metabolomic adaptations and correlates of survival to immune checkpoint blockade Li, Haoxin; Bullock, Kevin; Gurjao, Carino; Braun, David; Shukla, Sachet A.; Bosse, Dominick; Lalani, Aly-Khan A.; Gopal, Shuba; Jin, Chelsea; Horak, Christine; Wind-Rotolo, Megan; Signoretti, Sabina; McDermott, David F.; Freeman, Gordon J.; Van Allen, Eliezer M.; Schreiber, Stuart L.; Hodi, Frank Stephen; Sellers, William R.; Garraway, Levi A.; Clish, Clary B.; Choueiri, Toni K.; Giannakis, Marios Share Save
The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor-Positive Metastatic Breast Cancer Wander, Seth A.; Cohent, Ofir; Gong, Xueqian; Johnson, Gabriela N.; Buendia-Buendia, Jorge E.; Lloyd, Maxwell R.; Kim, Dewey; Luo, Flora; Mao, Pingping; Helvie, Karla; Kowalski, Kalley J.; Nayar, Utthara; Waks, Adrienne G.; Parsons, Stephen H.; Martinez, Ricardo; Litchfield, Lacey M.; Ye, Xiang S.; Yu, Chunping; Jansen, Valerie M.; Stille, John R.; Smith, Patricia S.; Oakley, Gerard J.; Chu, Quincy S.; Batist, Gerald; Hughes, Melissa E.; Kremer, Jill D.; Garraway, Levi A.; Winer, Erik P.; Tolaney, Sara M.; Lin, Nancy U.; Buchanan, Sean G.; Wagle, Nikhil Share Save
Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival Zaidi, Syed H.; Harrison, Tabitha A.; Phipps, Amanda, I; Steinfelder, Robert; Trinh, Quang M.; Qu, Conghui; Banbury, Barbara L.; Georgeson, Peter; Grasso, Catherine S.; Giannakis, Marios; Adams, Jeremy B.; Alwers, Elizabeth; Amitay, Efrat L.; Barfield, Richard T.; Berndt, Sonja, I; Borozan, Ivan; Brenner, Hermann; Brezina, Stefanie; Buchanan, Daniel D.; Cao, Yin; Chan, Andrew T.; Chang-Claude, Jenny; Connolly, Charles M.; Drew, David A.; Farris, Alton Brad, III; Figueiredo, Jane C.; French, Amy J.; Fuchs, Charles S.; Garraway, Levi A.; Gruber, Steve; Guinter, Mark A.; Hamilton, Stanley R.; Harlid, Sophia; Heisler, Lawrence E.; Hidaka, Akihisa; Hopper, John L.; Huang, Wen-Yi; Huyghe, Jeroen R.; Jenkins, Mark A.; Krzyzanowski, Paul M.; Lemire, Mathieu; Lin, Yi; Luo, Xuemei; Mardis, Elaine R.; McPherson, John D.; Miller, Jessica K.; Moreno, Victor; Mu, Xinmeng Jasmine; Nishihara, Reiko; Papadopoulos, Nickolas; Pasternack, Danielle; Quist, Michael J.; Rafikova, Adilya; Reid, Emma E. G.; Shinbrot, Eve; Shirts, Brian H.; Stein, Lincoln D.; Teney, Cherie D.; Timms, Lee; Um, Caroline Y.; Van Guelpen, Bethany; Van Tassel, Megan; Wang, Xiaolong; Wheeler, David A.; Yung, Christina K.; Hsu, Li; Ogino, Shuji; Gsur, Andrea; Newcomb, Polly A.; Gallinger, Steven; Hoffmeister, Michael; Campbell, Peter T.; Thibodeau, Stephen N.; Sun, Wei; Hudson, Thomas J.; Peters, Ulrike Share Save
A single-cell landscape of high-grade serous ovarian cancer Izar, Benjamin; Tirosh, Itay; Stover, Elizabeth H.; Wakiro, Isaac; Cuoco, Michael S.; Alter, Idan; Rodman, Christopher; Leeson, Rachel; Su, Mei-Ju; Shah, Parin; Iwanicki, Marcin; Walker, Sarah R.; Kanodia, Abhay; Melms, Johannes C.; Mei, Shaolin; Lin, Jia-Ren; Porter, Caroline B. M.; Slyper, Michal; Waldman, Julia; Jerby-Arnon, Livnat; Ashenberg, Orr; Brinker, Titus J.; Mills, Caitlin; Rogava, Meri; Vigneau, Sebastien; Sorger, Peter K.; Garraway, Levi A.; Konstantinopoulos, Panagiotis A.; Liu, Joyce F.; Matulonis, Ursula; Johnson, Bruce E.; Rozenblatt-Rosen, Orit; Rotem, Asaf; Regev, Aviv Share Save
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma (vol 25, pg 1915, 2019) Liu, David; Schilling, Bastian; Liu, Derek; Sucker, Antje; Livingstone, Elisabeth; Jerby-Arnon, Livnat; Zimmer, Lisa; Gutzmer, Ralf; Satzger, Imke; Loquai, Carmen; Grabbe, Stephan; Vokes, Natalie; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Gogas, Helen; Goldinger, Simone M.; Utikal, Jochen; Blank, Christian U.; Rauschenberg, Ricarda; von Bubnoff, Dagmar; Krackhardt, Angela; Weide, Benjamin; Haferkamp, Sebastian; Kiecker, Felix; Izar, Ben; Garraway, Levi; Regev, Aviv; Flaherty, Keith; Paschen, Annette; Van Allen, Eliezer M.; Schadendorf, Dirk Share Save
The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in patients with hormone receptor-positive (HR+)/HER2-metastatic breast cancer (MBC) Wander, Seth A.; Cohen, Ofir; Gong, Xueqian; Johnson, Gabriela N.; Buendia-Buendia, Jorge; Lloyd, Maxwell; Kim, Dewey; Luo, Flora; Mao, Pingping; Helvie, Karla; Kowalski, Kailey; Nayar, Utthara; Parsons, Stephen; Martinez, Ricardo; Litchfield, Lacey; Ye, Xiang; Yu, Chun Ping; Jansen, Valerie; Garraway, Levi A.; Winer, Eric P.; Tolaney, Sara M.; Lin, Nancy U.; Buchanan, Sean; Wagle, Nikhil Share Save
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma Liu, David; Schilling, Bastian; Liu, Derek; Sucker, Antje; Livingstone, Elisabeth; Jerby-Amon, Livnat; Zimmer, Lisa; Gutzmer, Ralf; Satzger, Imke; Loquai, Carmen; Grabbe, Stephan; Vokes, Natalie; Margolis, Claire A.; Conway, Jake; He, Meng Xiao; Elmarakeby, Haitham; Dietlein, Felix; Miao, Diana; Tracy, Adam; Gogas, Helen; Goldinger, Simone M.; Utikal, Jochen; Blank, Christian U.; Rauschenberg, Ricarda; von Bubnoff, Dagmar; Krackhardt, Angela; Weide, Benjamin; Haferkamp, Sebastian; Kiecker, Felix; Izar, Ben; Garraway, Levi; Regev, Aviv; Flaherty, Keith; Paschen, Annette; Van Allen, Eliezer M.; Schadendorf, Dirk Share Save
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Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer Stover, Elizabeth H.; Baco, Maria B.; Cohen, Ofir; Li, Yvonne Y.; Christie, Elizabeth L.; Bagul, Mukta; Goodale, Amy; Lee, Yenarae; Pantel, Sasha; Rees, Matthew G.; Wei, Guo; Presser, Adam G.; Gelbard, Maya K.; Zhang, Weiqun; Zervantonakis, Ioannis K.; Bhola, Patrick D.; Ryan, Jeremy; Guerriero, Jennifer L.; Montero, Joan; Liang, Felice J.; Cherniack, Andrew D.; Piccioni, Federica; Matulonis, Ursula A.; Bowtell, David D. L.; Sarosiek, Kristopher A.; Letai, Anthony; Garraway, Levi A.; Johannessen, Cory M.; Meyerson, Matthew Share Save
Metabolomic adaptations and correlates of survival to immune checkpoint blockade Li, Haoxin; Bullock, Kevin; Gurjao, Carino; Braun, David; Shukla, Sachet A.; Bosse, Dominick; Lalani, Aly-Khan A.; Gopal, Shuba; Jin, Chelsea; Horak, Christine; Wind-Rotolo, Megan; Signoretti, Sabina; McDermott, David F.; Freeman, Gordon J.; Van Allen, Eliezer M.; Schreiber, Stuart L.; Hodi, F. Stephen; Sellers, William R.; Garraway, Levi A.; Clish, Clary B.; Choueiri, Toni K.; Giannakis, Marios Share Save
6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels Li, Haoxin; Ericsson, Maria; Rabasha, Bokang; Budnik, Bogdan; Chan, Sze Ham; Freinkman, Elizaveta; Lewis, Caroline A.; Doench, John G.; Wagner, Bridget K.; Garraway, Levi A.; Schreiber, Stuart L. Share Save
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