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Neurotrophic factors for Parkinson's disease: Current status, progress, and remaining questions. Conclusions from a 2023 workshop Barker, Roger A.; Saarma, Mart; Svendsen, Clive N.; Morgan, Catherine; Whone, Alan; Fiandaca, Massimo S.; Luz, Matthias; Bankiewicz, Krystof S.; Fiske, Brian; Isaacs, Lyndsey; Roach, Arthur; Phipps, Thomas; Kordower, Jeffrey H.; Lane, Emma L.; Huttunen, Henri J.; Sullivan, Aideen; O'Keeffe, Gerard; Yartseva, Valeria; Federoff, Howard Share Save
Targeting Rap1b signaling cascades with CDNF: Mitigating platelet activation, plasma oxylipins and reperfusion injury in stroke Wu, Jui-Sheng; Lohelaid, Helike; Shih, Chih-Chin; Liew, Hock-Kean; Wang, Vicki; Hu, Wei-Fen; Chen, Yuan-Hao; Saarma, Mart; Airavaara, Mikko; Tseng, Kuan-Yin Share Save
RNA m6A methyltransferase activator affects anxiety-related behaviours, monoamines and striatal gene expression in the rat Kanarik, Margus; Liiver, Kristi; Norden, Marianna; Teino, Indrek; Org, Tonis; Laugus, Karita; Shimmo, Ruth; Karelson, Mati; Saarma, Mart; Harro, Jaanus Share Save
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Artesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis Guo, Xuanming; Asthana, Pallavi; Zhai, Lixiang; Cheng, Ka Wing; Gurung, Susma; Huang, Jiangang; Wu, Jiayan; Zhang, Yijing; Mahato, Arun Kumar; Saarma, Mart; Ustav, Mart; Kwan, Hiu Yee; Lyu, Aiping; Chan, Kui Ming; Xu, Pingyi; Bian, Zhao-Xiang; Wong, Hoi Leong Xavier Share Save
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Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double-Blind, Multicenter Phase 1 Trial Huttunen, Henri J. J.; Booms, Sigrid; Sjogren, Magnus; Kerstens, Vera; Johansson, Jarkko; Holmnas, Rebecka; Koskinen, Jani; Kulesskaya, Natalia; Fazio, Patrik; Woolley, Max; Brady, Alan; Williams, Julia; Johnson, David; Dailami, Narges; Gray, William; Levo, Reeta; Saarma, Mart; Halldin, Christer; Marjamaa, Johan; Resendiz-Nieves, Julio; Grubor, Irena; Lind, Goran; Eerola-Rautio, Johanna; Mertsalmi, Tuomas; Andreasson, Mattias; Paul, Gesine; Rinne, Juha; Kivisaari, Riku; Bjartmarz, Hjalmar; Almqvist, Per; Varrone, Andrea; Scheperjans, Filip; Widner, Hakan; Svenningsson, Per Share Save
CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress De Lorenzo, Francesca; Luningschror, Patrick; Nam, Jinhan; Beckett, Liam; Pilotto, Federica; Galli, Emilia; Lindholm, Paivi; von Collenberg, Cora Rudt; Mungwa, Simon Tii; Jablonka, Sibylle; Kauder, Julia; Thau-Habermann, Nadine; Petri, Susanne; Lindholm, Dan; Saxena, Smita; Sendtner, Michael; Saarma, Mart; Voutilainen, Merja H. Share Save
Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage Tseng, Kuan-Yin; Stratoulias, Vassilis; Hu, Wei-Fen; Wu, Jui-Sheng; Wang, Vicki; Chen, Yuan-Hao; Seelbach, Anna; Huttunen, Henri J.; Kulesskaya, Natalia; Pang, Cheng-Yoong; Chou, Jian-Liang; Lindahl, Maria; Saarma, Mart; Huang, Li-Chuan; Airavaara, Mikko; Liew, Hock-Kean Share Save
MANF regulates neuronal survival and UPR through its ER-located receptor IRE1a Kovaleva, Vera; Yu, Li-Ying; Ivanova, Larisa; Shpironok, Olesya; Nam, Jinhan; Eesmaa, Ave; Kumpula, Esa-Pekka; Sakson, Sven; Toots, Urve; Ustav, Mart; Huiskonen, Juha T.; Voutilainen, Merja H.; Lindholm, Paivi; Karelson, Mati; Saarma, Mart Share Save
The Unconventional Growth Factors Cerebral Dopamine Neurotrophic Factor and Mesencephalic Astrocyte-Derived Neurotrophic Factor Promote Post-ischemic Neurological Recovery, Perilesional Brain Remodeling, and Lesion-Remote Axonal Plasticity Caglayan, Ahmet Burak; Beker, Mustafa Caglar; Sertel Evren, Elif; Caglayan, Berrak; Kilic, Ulkan; Ates, Nilay; Caglayan, Aysun; Dasdelen, Muhammed Furkan; Doeppner, Thorsten Roland; Saarma, Mart; Hermann, Dirk Matthias; Kilic, Ertugrul Share Save
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MANF supports the inner hair cell synapse and the outer hair cell stereocilia bundle in the cochlea Ikaheimo, Kuu; Herranen, Anni; Iivanainen, Vilma; Lankinen, Tuuli; Aarnisalo, Antti A.; Sivonen, Ville; Patel, Kashyap A.; Demir, Korcan; Saarma, Mart; Lindahl, Maria; Pirvola, Ulla Share Save
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo Albert, Katrina; Raymundo, Diana P.; Panhelainen, Anne; Eesmaa, Ave; Shvachiy, Liana; Araujo, Gabriela R.; Chmielarz, Piotr; Yan, Xu; Singh, Aastha; Cordeiro, Yraima; Palhano, Fernando L.; Foguel, Debora; Luk, Kelvin C.; Domanskyi, Andrii; Voutilainen, Merja H.; Huttunen, Henri J.; Outeiro, Tiago F.; Saarma, Mart; Almeida, Marcius S.; Airavaara, Mikko Share Save
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