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Liposomal lipid nanoparticles for extrahepatic delivery of mRNA Cheng, Miffy Hok Yan; Zhang, Yao; Fox, Kevin; Leung, Jerry; Strong, Colton; Kang, Emma; Chen, Yihang; Tong, Michelle; Bommadevara, Hemashree; Jan, Eric; Ip, Owen Yuk Long; Rodriguez-Rodriguez, Cristina; Saatchi, Katayoun; Hafeli, Urs O.; Abdolahzadeh, Amir; Witzigmann, Dominik; Cullis, Pieter R. Share Save
Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing global translation inhibition Panzhinskiy, Evgeniy; Skovso, Sos; Cen, Haoning Howard; Rahardjo, Amanda; Zhang, Jiashuo Aaron; Chu, Kwan Yi; Macdonald, Kate; Soukhatcheva, Galina; Dionne, Derek A.; Hallmaier-Wacker, Luisa K.; Wildi, Jennifer S.; Marcil, Stephanie; Noursadeghi, Nilou; Taghizadeh, Farnaz; Verchere, C. Bruce; Jan, Eric; Johnson, James D. Share Save
Protein is expressed in all major organs after intravenous infusion of mRNA-lipid nanoparticles in swine Ferraresso, Francesca; Badior, Katherine; Seadler, Monica; Zhang, Youjie; Wietrzny, Amanda; Cau, Massimo F.; Haugen, Amber; Rodriguez, Geoffrey G.; Dyer, Mitchell R.; Cullis, Pieter R.; Jan, Eric; Kastrup, Christian J. Share Save
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Genetically engineered transfusable platelets using mRNA lipid nanoparticles Leung, Jerry; Strong, Colton; Badior, Katherine E.; Robertson, Madelaine; Wu, Xiaowu; Meledeo, Michael A.; Kang, Emma; Paul, Manoj; Sato, Yusuke; Harashima, Hideyoshi; Cap, Andrew P.; Devine, Dana V.; Jan, Eric; Cullis, Pieter R.; Kastrup, Christian J. Share Save
Lipid Nanoparticle-Mediated Hit-and-Run Approaches Yield Efficient and Safe In Situ Gene Editing in Human Skin Bolsoni, Juliana; Liu, Danny; Mohabatpour, Fatemeh; Ebner, Ronja; Sadhnani, Gaurav; Tafech, Belal; Leung, Jerry; Shanta, Selina; An, Kevin; Morin, Tessa; Chen, Yihang; Arguello, Alfonso; Choate, Keith; Jan, Eric; Ross, Colin J. D.; Brambilla, Davide; Witzigmann, Dominik; Kulkarni, Jayesh; Cullis, Pieter R.; Hedtrich, Sarah Share Save
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Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency Cheng, Miffy Hok Yan; Leung, Jerry; Zhang, Yao; Strong, Colton; Basha, Genc; Momeni, Arash; Chen, Yihang; Jan, Eric; Abdolahzadeh, Amir; Wang, Xinying; Kulkarni, Jayesh A. A.; Witzigmann, Dominik; Cullis, Pieter R. R. Share Save
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The Hinge Region of the Israeli Acute Paralysis Virus Internal Ribosome Entry Site Directs Ribosomal Positioning, Translational Activity, and Virus Infection Kirby, Mathew P.; Stevenson, Ciara; Worrall, Liam J.; Chen, Yihang; Young, Christina; Youm, Jisoo; Strynadka, Natalie C. J.; Allan, Douglas W.; Jan, Eric Share Save
Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome Pablos, Isabel; Machado, Yoan; de Jesus, Hugo C. Ramos; Mohamud, Yasir; Kappelhoff, Reinhild; Lindskog, Cecilia; Vlok, Marli; Bell, Peter A.; Butler, Georgina S.; Grin, Peter M.; Cao, Quynh T.; Nguyen, Jenny P.; Solis, Nestor; Abbina, Srinivas; Rut, Wioletta; Vederas, John C.; Szekely, Laszlo; Szakos, Attila; Drag, Marcin; Kizhakkedathu, Jayachandran N.; Mossman, Karen; Hirota, Jeremy A.; Jan, Eric; Luo, Honglin; Banerjee, Arinjay; Overall, Christopher M. Share Save
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