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Autoantibodies neutralizing type I IFNs in patients with fulminant herpes simplex virus hepatitis Gervais, Adrian; Marchal, Astrid; Boucherit, Soraya; Abi Haidar, Anthony; Bizien, Lucy; Yalcinkaya, Ahmet; Sandstrom, Ella; Kong, Xiao-Fei; Jacquemin, Emmanuel; Bernard, Olivier; Debray, Dominique; Lacaille, Florence; Ichai, Philippe; Arikan, Cigdem; Javouhey, Etienne; Roquelaure, Bertrand; Gottrand, Frederic; Trespidi, Francesca; Codullo, Veronica; Cavagna, Lorenzo; Schleinitz, Nicolas; Bousfiha, Mohamed; Amenzoui, Naima; Bousfiha, Ahmed Aziz; Jorgensen, Sofie E.; Mork, Nanna; Mogensen, Trine H.; Bastard, Paul; Puel, Anne; Borghesi, Alessandro; Rule, Jody A.; Lee, William M.; Landegren, Nils; Cobat, Aurelie; Casanova, Jean-Laurent; Jouanguy, Emmanuelle Share Save
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Application of whole-exome sequencing to predict inborn errors of immunity in pediatric severe infections and sepsis Moundir, Abderrahmane; Aissaoui, Ouissal; Akhrichi, Nassima; Allaoui, Abire; Benhsaien, Ibtihal; Jouanguy, Emmanuelle; Casanova, Jean-Laurent; El Bakkouri, Jalila; Ailal, Fatima; Bousfiha, Ahmed Aziz Share Save
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Complement system activation: bridging physiology, pathophysiology, and therapy Azoulay, Elie; Zuber, Julien; Bousfiha, Ahmed Aziz; Long, Yun; Tan, Ying; Luo, Sushan; Essafti, Meriem; Annane, Djillali Share Save
Case Report of Two Independent Moroccan Families with Syndromic Epidermodysplasia Verruciformis and STK4 Deficiency El Kettani, Assiya; Ouair, Hind; Marnissi, Farida; El Bakkouri, Jalila; Chevalier, Remi; Lorenzo, Lazaro; Kholaiq, Halima; Beziat, Vivien; Jouanguy, Emmanuelle; Casanova, Jean-Laurent; Bousfiha, Ahmed Aziz Share Save
Human genetic and immunological determinants of SARS-CoV-2 infection and multisystem inflammatory syndrome in children Kholaiq, Halima; Abdelmoumen, Yousra; Moundir, Abderrahmane; El Kettani, Assiya; Ailal, Fatima; Benhsaien, Ibtihal; Adnane, Fatima; Bourhanbour, Asmaa Drissi; Amenzoui, Naima; El Bakkouri, Jalila; Bousfiha, Ahmed Aziz Share Save
Higher COVID-19 pneumonia risk associated with anti-IFN-α than with anti-IFN-ω auto-Abs in children Bastard, Paul; Gervais, Adrian; Taniguchi, Maki; Saare, Liisa; Sarekannu, Karita; Le Voyer, Tom; Philippot, Quentin; Rosain, Jeremie; Bizien, Lucy; Asano, Takaki; Garcia-Prat, Marina; Parra-Martinez, Alba; Migaud, Melanie; Tsumura, Miyuki; Conti, Francesca; Belot, Alexandre; Riviere, Jacques G.; Morio, Tomohiro; Tanaka, Junko; Javouhey, Etienne; Haerynck, Filomeen; Duvlis, Sotirija; Ozcelik, Tayfun; Keles, Sevgi; Tandjaoui-Lambiotte, Yacine; Escoda, Simon; Husain, Maya; Pan-Hammarstrom, Qiang; Hammarstrom, Lennart; Ahlijah, Gloria; Haidar, Anthony Abi; Soudee, Camille; Arseguel, Vincent; Abolhassani, Hassan; Sahanic, Sabina; Tancevski, Ivan; Nukui, Yoko; Hayakawa, Seiichi; Chrousos, George P.; Michos, Athanasios; Tatsi, Elizabeth-Barbara; Filippatos, Filippos; Rodriguez-Palmero, Agusti; Troya, Jesus; Tipu, Imran; Meyts, Isabelle; Roussel, Lucie; Ostrowski, Sisse Rye; Schidlowski, Laire; Prando, Carolina; Condino-Neto, Antonio; Cheikh, Nathalie; Bousfiha, Ahmed A.; El Bakkouri, Jalila; Peterson, Part; Pujol, Aurora; Levy, Romain; Quartier, Pierre; Vinh, Donald C.; Boisson, Bertrand; Beziat, Vivien; Zhang, Shen-Ying; Borghesi, Alessandro; Pession, Andrea; Andreakos, Evangelos; Marr, Nico; Mentis, Alexios-Fotios A.; Mogensen, Trine H.; Rodriguez-Gallego, Carlos; Soler-Palacin, Pere; Colobran, Roger; Tillmann, Vallo; Neven, Benedicte; Trouillet-Assant, Sophie; Brodin, Petter; Abel, Laurent; Jouanguy, Emmanuelle; Zhang, Qian; Martinon-Torres, Federico; Salas, Antonio; Gomez-Carballa, Alberto; Gonzalez-Granado, Luis I.; Kisand, Kai; Okada, Satoshi; Puel, Anne; Cobat, Aurelie; Casanova, Jean-Laurent Share Save
Atypical Cutaneous Viral Infections Reveal an Inborn Error of Immunity in 8 Patients El Kettani, Assiya; Ailal, Fatima; Marnissi, Farida; Hali, Fouzia; El Bakkouri, Jalila; Benhsaien, Ibtihal; Le Voyer, Tom; Gueye, Mame Sokhna; Chevalier, Remi; Chiheb, Soumiya; Zerouali, Khalid; Jouanguy, Emmanuelle; Casanova, Jean-Laurent; Bousfiha, Ahmed Aziz Share Save
Mendelian Susceptibility to Mycobacterial Disease (MSMD): Clinical, Immunological, and Genetic Features of 22 Patients from 15 Moroccan Kindreds Errami, Abderrahmane; Baghdadi, Jamila El; Ailal, Fatima; Benhsaien, Ibtihal; Bakkouri, Jalila El; Jeddane, Leila; Rada, Noureddine; Benajiba, Noufissa; Mokhantar, Khaoula; Ouazahrou, Kaoutar; Zaidi, Sanae; Abel, Laurent; Casanova, Jean-Laurent; Boisson-Dupuis, Stephanie; Bustamante, Jacinta; Bousfiha, Ahmed Aziz Share Save
Genetic Diagnosis of Inborn Errors of Immunity in an Emerging Country: a Retrospective Study of 216 Moroccan Patients Moundir, Abderrahmane; Ouair, Hind; Benhsaien, Ibtihal; Jeddane, Leila; Rada, Nouredine; Amenzoui, Naima; Jouhadi, Zineb; Adnane, Fatima; El Hafidi, Naima; Kili, Amina; Drissi, Asmaa Bourhanbour; Babakhouya, Abdeladim; Benmiloud, Sarra; Hbibi, Mohamed; Benajiba, Noufissa; Hida, Mustapha; Bouskraoui, Mohamed; Mahraoui, Chafiq; Admou, Brahim; El Bakkouri, Jalila; Ailal, Fatima; Bousfiha, Ahmed Aziz Share Save
Inborn errors of immunity and related microbiome Hazime, Raja; Eddehbi, Fatima-Ezzohra; El Mojadili, Saad; Lakhouaja, Nadia; Souli, Ikram; Salami, Abdelmouine; M'Raouni, Bouchra; Brahim, Imane; Oujidi, Mohamed; Guennouni, Morad; Bousfiha, Ahmed Aziz; Admou, Brahim Share Save
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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies Manry, Jeremy; Bastard, Paul; Gervais, Adrian; Le Voyer, Tom; Rosain, Jeremie; Philippot, Quentin; Michailidis, Eleftherios; Hoffmann, Hans-Heinrich; Eto, Shohei; Garcia-Prat, Marina; Bizien, Lucy; Parra-Martinez, Alba; Yang, Rui; Haljasmagi, Liis; Migaud, Melanie; Sarekannu, Karita; Maslovskaja, Julia; de Prost, Nicolas; Tandjaoui-Lambiotte, Yacine; Luyt, Charles-Edouard; Amador-Borrero, Blanca; Gaudet, Alexandre; Poissy, Julien; Morel, Pascal; Richard, Pascale; Cognasse, Fabrice; Troya, Jesus; Trouillet-Assant, Sophie; Belot, Alexandre; Saker, Kahina; Garcon, Pierre; Riviere, Jacques G.; Lagier, Jean-Christophe; Gentile, Stephanie; Rosen, Lindsey B.; Shaw, Elana; Morio, Tomohiro; Tanaka, Junko; Dalmau, David; Tharaux, Pierre-Louis; Sene, Damien; Stepanian, Alain; Megarbane, Bruno; Triantafyllia, Vasiliki; Fekkar, Arnaud; Heath, James R.; Franco, Jose Luis; Anaya, Juan-Manuel; Sole-Violan, Jordi; Imberti, Luisa; Biondi, Andrea; Bonfanti, Paolo; Castagnoli, Riccardo; Delmonte, Ottavia M.; Zhang, Yu; Snow, Andrew L.; Holland, Steven M.; Biggs, Catherine M.; Moncada-Velez, Marcela; Arias, Andres Augusto; Lorenzo, Lazaro; Boucherit, Soraya; Anglicheau, Dany; Planas, Anna M.; Haerynck, Filomeen; Duvlis, Sotirija; Ozcelik, Tayfun; Keles, Sevgi; Bousfiha, Ahmed A.; El Bakkouri, Jalila; Ramirez-Santana, Carolina; Paul, Stephane; Pan-Hammarstrom, Qiang; Hammarstrom, Lennart; Dupont, Annabelle; Kurolap, Alina; Metz, Christine N.; Aiuti, Alessandro; Casari, Giorgio; Lampasona, Vito; Ciceri, Fabio; Barreiros, Lucila A.; Dominguez-Garrido, Elena; Vidigal, Mateus; Zatz, Mayana; van de Beek, Diederik; Sahanic, Sabina; Tancevski, Ivan; Stepanovskyy, Yurii; Boyarchuk, Oksana; Nukui, Yoko; Tsumura, Miyuki; Vidaur, Loreto; Tangye, Stuart G.; Burrel, Sonia; Duffy, Darragh; Quintana-Murci, Lluis; Klocperk, Adam; Kann, Nelli Y.; Shcherbina, Anna; Lau, Yu-Lung; Leung, Daniel; Coulongeat, Matthieu; Marlet, Julien; Koning, Rutger; Reyes, Luis Felipe; Chauvineau-Grenier, Angelique; Venet, Fabienne; Monneret, Guillaume; Nussenzweig, Michel C.; Arrestier, Romain; Boudhabhay, Idris; Baris-Feldman, Hagit; Hagin, David; Wauters, Joost; Meyts, Isabelle; Dyer, Adam H.; Kennelly, Sean; Bourkeh, Nollaig M.; Halwan, Rabih; Sharif-Askar, Fatemeh Saheb; Dorgham, Karim; Sallette, Jerome; Sedkaoui, Souad Mehlal; AlKhater, Suzan; Rigo-Bonnin, Raul; Morandeira, Francisco; Roussel, Lucie; Vinh, Donald C.; Erikstrup, Christian; Condino-Neto, Antonio; Prando, Carolina; Bondarenko, Anastasiia; Spaan, Andras N.; Gilardin, Laurent; Fellay, Jacques; Lyonnet, Stanislas; Bilguvar, Kaya; Lifton, Richard P.; Mane, Shrikant; Anderson, Mark S.; Boisson, Bertrand; Beziat, Vivien; Zhang, Shen-Ying; Andreakos, Evangelos; Hermine, Olivier; Pujol, Aurora; Peterson, Part; Mogensen, Trine H.; Rowen, Lee; Mond, James; Debette, Stephanie; de Lamballerie, Xavier; Burdet, Charles; Bouadma, Lila; Zins, Marie; Soler-Palacin, Pere; Colobran, Roger; Gorochov, Guy; Solanich, Xavier; Susen, Sophie; Martinez-Picado, Javier; Raoult, Didier; Vasse, Marc; Gregersen, Peter K.; Piemonti, Lorenzo; Rodriguez-Gallego, Carlos; D Notarangelo, Luigi; Su, Helen C.; Kisand, Kai; Okada, Satoshi; Puel, Anne; Jouanguy, Emmanuelle; Rice, Charles M.; Tiberghien, Pierre; Zhang, Qian; Casanova, Jean-Laurent; Abel, Laurent; Cobat, Aurelie Share Save
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agents Levy, Romain; Langlais, David; Beziat, Vivien; Rapaport, Franck; Rao, Geetha; Lazarov, Tomi; Bourgey, Mathieu; Zhou, Yu J.; Briand, Coralie; Moriya, Kunihiko; Ailal, Fatima; Avery, Danielle T.; Markle, Janet; Lim, Ai Ing; Ogishi, Masato; Yang, Rui; Pelham, Simon; Emam, Mehdi; Migaud, Melanie; Deswarte, Caroline; Habib, Tanwir; Saraiva, Luis R.; Moussa, Eman A.; Guennoun, Andrea; Boisson, Bertrand; Belkaya, Serkan; Martinez-Barricarte, Ruben; Rosain, Jeremie; Belkadi, Aziz; Breton, Sylvain; Payne, Kathryn; Benhsaien, Ibtihal; Plebani, Alessandro; Lougaris, Vassilios; Di Santo, James P.; Neven, Benedicte; Abel, Laurent; Ma, Cindy S.; Bousfiha, Ahmed Aziz; Marr, Nico; Bustamante, Jacinta; Liu, Kang; Gros, Philippe; Geissmann, Frederic; Tangye, Stuart G.; Casanova, Jean-Laurent; Puel, Anne Share Save
Autoantibodies neutralizing type I IFNs are present in ∼4% of uninfected individuals over 70 years old and account for ∼20% of COVID-19 deaths Bastard, Paul; Gervais, Adrian; Le Voyer, Tom; Rosain, Jeremie; Philippot, Quentin; Manry, Jeremy; Michailidis, Eleftherios; Hoffmann, Hans-Heinrich; Eto, Shohei; Garcia-Prat, Marina; Bizien, Lucy; Parra-Martinez, Alba; Yang, Rui; Haljasmagi, Liis; Migaud, Melanie; Sarekannu, Karita; Maslovskaja, Julia; de Prost, Nicolas; Tandjaoui-Lambiotte, Yacine; Luyt, Charles-Edouard; Amador-Borrero, Blanca; Gaudet, Alexandre; Poissy, Julien; Morel, Pascal; Richard, Pascale; Cognasse, Fabrice; Troya, Jesus; Trouillet-Assant, Sophie; Belot, Alexandre; Saker, Kahina; Garcon, Pierre; Riviere, Jacques G.; Lagier, Jean-Christophe; Gentile, Stephanie; Rosen, Lindsey B.; Shaw, Elana; Morio, Tomohiro; Tanaka, Junko; Dalmau, David; Tharaux, Pierre-Louis; Sene, Damien; Stepanian, Alain; Megarbane, Bruno; Triantafyllia, Vasiliki; Fekkar, Arnaud; Heath, James R.; Franco, Jose Luis; Anaya, Juan-Manuel; Sole-Violan, Jordi; Imberti, Luisa; Biondi, Andrea; Bonfanti, Paolo; Castagnoli, Riccardo; Delmonte, Ottavia M.; Zhang, Yu; Snow, Andrew L.; Holland, Steven M.; Biggs, Catherine M.; Moncada-Velez, Marcela; Arias, Andres Augusto; Lorenzo, Lazaro; Boucherit, Soraya; Coulibaly, Boubacar; Anglicheau, Dany; Planas, Anna M.; Haerynck, Filomeen; Duvlis, Sotirija; Nussbaum, Robert L.; Ozcelik, Tayfun; Keles, Sevgi; Bousfiha, Ahmed A.; El Bakkouri, Jalila; Ramirez-Santana, Carolina; Paul, Stephane; Pan-Hammarstrom, Qiang; Hammarstrom, Lennart; Dupont, Annabelle; Kurolap, Alina; Metz, Christine N.; Aiuti, Alessandro; Casari, Giorgio; Lampasona, Vito; Ciceri, Fabio; Barreiros, Lucila A.; Dominguez-Garrido, Elena; Vidigal, Mateus; Zatz, Mayana; van de Beek, Diederik; Sahanic, Sabina; Tancevski, Ivan; Stepanovskyy, Yurii; Boyarchuk, Oksana; Nukui, Yoko; Tsumura, Miyuki; Vidaur, Loreto; Tangye, Stuart G.; Burrel, Sonia; Duffy, Darragh; Quintana-Murci, Lluis; Klocperk, Adam; Kann, Nelli Y.; Shcherbina, Anna; Lau, Yu-Lung; Leung, Daniel; Coulongeat, Matthieu; Marlet, Julien; Koning, Rutger; Reyes, Luis Felipe; Chauvineau-Grenier, Angelique; Venet, Fabienne; Monneret, Guillaume; Nussenzweig, Michel C.; Arrestier, Romain; Boudhabhay, Idris; Baris-Feldman, Hagit; Hagin, David; Wauters, Joost; Meyts, Isabelle; Dyer, Adam H.; Kennelly, Sean P.; Bourke, Nollaig M.; Halwani, Rabih; Sharif-Askari, Narjes Saheb; Dorgham, Karim; Sallette, Jerome; Sedkaoui, Souad Mehlal; AlKhater, Suzan; Rigo-Bonnin, Raul; Morandeira, Francisco; Roussel, Lucie; Vinh, Donald C.; Ostrowski, Sisse Rye; Condino-Neto, Antonio; Prando, Carolina; Bondarenko, Anastasiia; Spaan, Andras N.; Gilardin, Laurent; Fellay, Jacques; Lyonnet, Stanislas; Bilguvar, Kaya; Lifton, Richard P.; Mane, Shrikant; Anderson, Mark S.; Boisson, Bertrand; Beziat, Vivien; Zhang, Shen-Ying; Andreakos, Evangelos; Hermine, Olivier; Pujol, Aurora; Peterson, Part; Mogensen, Trine H.; Rowen, Lee; Mond, James; Debette, Stephanie; de Lamballerie, Xavier; Duval, Xavier; Mentre, France; Zins, Marie; Soler-Palacin, Pere; Colobran, Roger; Gorochov, Guy; Solanich, Xavier; Susen, Sophie; Martinez-Picado, Javier; Raoult, Didier; Vasse, Marc; Gregersen, Peter K.; Piemonti, Lorenzo; Rodriguez-Gallego, Carlos; Notarangelo, Luigi D.; Su, Helen C.; Kisand, Kai; Okada, Satoshi; Puel, Anne; Jouanguy, Emmanuelle; Rice, Charles M.; Tiberghien, Pierre; Zhang, Qian; Cobat, Aurelie; Abel, Laurent; Casanova, Jean-Laurent Share Save
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