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SaveShare Save In vivo CRISPR screens reveal SCAF1 and USP15 as drivers of pancreatic cancer
Martinez, Sebastien; Wu, Shifei; Geuenich, Michael; Malik, Ahmad; Weber, Ramona; Woo, Tristan; Zhang, Amy; Jang, Gun Ho; Dervovic, Dzana; Al-Zahrani, Khalid N.; Tsai, Ricky; Fodil, Nassima; Gros, Philippe; Gallinger, Steven; Neely, G. Gregory; Notta, Faiyaz; Sendoel, Ataman; Campbell, Kieran; Elling, Ulrich; Schramek, Daniel Share Save The potential importance of the built- environment microbiome and its impact on human healthBosch, Thomas C. G.; Wigley, Mark; Colomina, Beatriz; Bohannan, Brendan; Meggers, Forrest; Amato, Katherine R.; Azad, Meghan B.; Blaser, Martin J.; Brown, Kate; Dominguez-Bello, Maria Gloria; Ehrlich, Stanislav Dusko; Elinav, Eran; Finlay, B. Brett; Geddie, Kate; Geva-Zatorsky, Naama; Giles-Vernick, Tamara; Gros, Philippe; Guillemin, Karen; Haraoui, Louis Patrick; Johnson, Elizabeth; Keck, Frederic; Lorimer, Jamie; McFall-Ngai, Margaret J.; Nichter, Mark; Pettersson, Sven; Poinar, Hendrik; Rees, Tobias; Tropini, Carolina; Undurraga, Eduardo A.; Zhao, Liping; Melby, Melissa K. Share Save CCDC88B interacts with RASAL3 and ARHGEF2 and regulates dendritic cell function in neuroinflammation and colitisOlivier, Jean-Frederic; Langlais, David; Jeyakumar, Thiviya; Polyak, Maria J.; Galarneau, Luc; Cayrol, Romain; Jiang, Hua; Molloy, Kelly R.; Xu, Guoyue; Suzuki, Harumi; Lacava, John; Gros, Philippe; Fodil, Nassima Share Save A novel pediatric polycystic lung disease caused by CCR2 deficiencyNeehus, Anna-Lena; Landekic, Marija; Rinchai, Darawan; Panikulam, Patricia; Philippot, Quentin; Le Voyer, Tom; Ogishi, Masato; Rosain, Jeremie; Momenilandi, Mana; Franco, Carlos Andres Arango; Martin-Fernandez, Marta; Khan, Taushif; Bohlen, Jonathan; Manry, Jeremy; Han, Ji Eun; Deslys, Alexandre; Gajardo-Carrasco, Tania; Soudee, Camille; Migaud, Melanie; Seeleuthner, Yoann; Nikolouli, Eirini; Seyedpour, Simin; Begueret, Hugues; Brouzes, Chantal; Vargas, Pablo; Lachmann, Nico; Boire, Raphael; Marr, Nico; Bugonovic, Dusan; Modaresi, Mohammadreza; Nogee, Larry; Craven, Daniel; Mohamadzadeh, Iraj; Rezai, Nima; Shahrooei, Mohammad; Boisson-Dupuis, Stephanie; Sepulveda, Fernando; Beziat, Vivien; Aladjidi, Nathalie; Abel, Laurent; Gros, Philippe; Malo, Danielle; Young, Lisa; Deterding, Robin; Deutsch, Gail; Carey, Brenna; Trapnell, Bruce; Casanova, Jean-Laurent; Bustamante, Jacinta Share Save Share Save Deubiquitinase catalytic activity of MYSM1 is essential in vivo for hematopoiesis and immune cell developmentLiang, Yue; Bhatt, Garvit; Tung, Lin Tze; Wang, HanChen; Kim, Joo Eun; Mousa, Marwah; Plackoska, Viktoria; Illes, Katalin; Georges, Anna A.; Gros, Philippe; Henneman, Linda; Huijbers, Ivo J.; Nagar, Bhushan; Nijnik, Anastasia Share Save Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to multiple infectious agentsLevy, Romain; Langlais, David; Beziat, Vivien; Rapaport, Franck; Rao, Geetha; Lazarov, Tomi; Bourgey, Mathieu; Zhou, Yu J.; Briand, Coralie; Moriya, Kunihiko; Ailal, Fatima; Avery, Danielle T.; Markle, Janet; Lim, Ai Ing; Ogishi, Masato; Yang, Rui; Pelham, Simon; Emam, Mehdi; Migaud, Melanie; Deswarte, Caroline; Habib, Tanwir; Saraiva, Luis R.; Moussa, Eman A.; Guennoun, Andrea; Boisson, Bertrand; Belkaya, Serkan; Martinez-Barricarte, Ruben; Rosain, Jeremie; Belkadi, Aziz; Breton, Sylvain; Payne, Kathryn; Benhsaien, Ibtihal; Plebani, Alessandro; Lougaris, Vassilios; Di Santo, James P.; Neven, Benedicte; Abel, Laurent; Ma, Cindy S.; Bousfiha, Ahmed Aziz; Marr, Nico; Bustamante, Jacinta; Liu, Kang; Gros, Philippe; Geissmann, Frederic; Tangye, Stuart G.; Casanova, Jean-Laurent; Puel, Anne Share Save Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a childOgishi, Masato; Yang, Rui; Aytekin, Caner; Langlais, David; Bourgey, Mathieu; Khan, Taushif; Al Ali, Fatima; Rahman, Mahbuba; Delmonte, Ottavia M.; Chrabieh, Maya; Zhang, Peng; Gruber, Conor; Pelham, Simon J.; Spaan, Andras N.; Rosain, Jeremie; Lei, Wei-Te; Drutman, Scott; Hellmann, Matthew D.; Callahan, Margaret K.; Adamow, Matthew; Wong, Phillip; Wolchok, Jedd D.; Rao, Geetha; Ma, Cindy S.; Nakajima, Yuka; Yaguchi, Tomonori; Chamoto, Kenji; Williams, Samuel C.; Emile, Jean-Francois; Rozenberg, Flore; Glickman, Michael S.; Rapaport, Franck; Kerner, Gaspard; Allington, Garrett; Tezcan, Ilhan; Cagdas, Deniz; Hosnut, Ferda O.; Dogu, Figen; Ikinciogullari, Aydan; Rao, V. Koneti; Kainulainen, Leena; Beziat, Vivien; Bustamante, Jacinta; Vilarinho, Silvia; Lifton, Richard P.; Boisson, Bertrand; Abel, Laurent; Bogunovic, Dusan; Marr, Nico; Notarangelo, Luigi D.; Tangye, Stuart G.; Honjo, Tasuku; Gros, Philippe; Boisson-Dupuis, Stephanie; Casanova, Jean-Laurent Share Save Share Save The hygiene hypothesis, the COVID pandemic, and consequences for the human microbiomeFinlay, B. Brett; Amato, Katherine R.; Azad, Meghan; Blaser, Martin J.; Bosch, Thomas C. G.; Chu, Hiutung; Dominguez-Bello, Maria Gloria; Ehrlich, Stanislav Dusko; Elinav, Eran; Geva-Zatorsky, Naama; Gros, Philippe; Guillemin, Karen; Keck, Frederic; Korem, Tal; McFall-Ngai, Margaret J.; Melby, Melissa K.; Nichter, Mark; Pettersson, Sven; Poinar, Hendrik; Rees, Tobias; Tropini, Carolina; Zhao, Liping; Giles-Vernick, Tamara Share Save Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced AnemiaXu, Guoyue; van Bruggen, Rebekah; Gualtieri, Christian O.; Moradin, Neda; Fois, Adrien; Vallerand, Diane; Russo, Mariana De Sa Tavares; Bassenden, Angelia; Lu, Wenyun; Tam, Mifong; Lesage, Sylvie; Girouard, Helene; Avizonis, Daina Zofija; Deblois, Genevieve; Prchal, Josef T.; Stevenson, Mary; Berghuis, Albert; Muir, Tom; Rabinowitz, Joshua; Vidal, Silvia M.; Fodil, Nassima; Gros, Philippe Share Save MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunctionBelle, Jad I.; Wang, HanChen; Fiore, Amanda; Petrov, Jessica C.; Lin, Yun Hsiao; Feng, Chu-Han; Thi Tuyet Mai Nguyen; Tung, Jacky; Campeau, Philippe M.; Behrends, Uta; Brunet, Theresa; Leszinski, Gloria Sarah; Gros, Philippe; Langlais, David; Nijnik, Anastasia Share Save Share Save Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal CancerJeyakumar, Thiviya; Fodil, Nassima; Van der Kraak, Lauren; Meunier, Charles; Cayrol, Romain; McGregor, Kevin; Langlais, David; Greenwood, Celia M. T.; Beauchemin, Nicole; Gros, Philippe Share Save Share Save Share Save INACTIVATION OF IRF1 CAUSES SUSCEPTIBILITY TO COLITIS-ASSOCIATED COLORECTAL CANCERJeyakumar, Thiviya; Fodil, Nassima; Van der Kraak, Lauren; Meunier, Charles; Cayrol, Romain; McGregor, Kevin; Langlais, David; Greenwood, Celia; Beauchemin, Nicole; Gros, Philippe Share Save Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiencyKong, Xiao-Fei; Martinez-Barricarte, Ruben; Kennedy, James; Mele, Federico; Lazarov, Tomi; Deenick, Elissa K.; Ma, Cindy S.; Breton, Gaelle; Lucero, Kimberly B.; Langlais, David; Bousfiha, Aziz; Aytekin, Caner; Markle, Janet; Trouillet, Celine; Jabot-Hanin, Fabienne; Arlehamn, Cecilia S. Lindestam; Rao, Geetha; Picard, Capucine; Lasseau, Theo; Latorre, Daniela; Hambleton, Sophie; Deswarte, Caroline; Itan, Yuval; Abarca, Katia; Moraes-Vasconcelos, Dewton; Ailal, Fatima; Ikinciogullari, Aydan; Dogu, Figen; Benhsaien, Ibtihal; Sette, Alessandro; Abel, Laurent; Boisson-Dupuis, Stephanie; Schroeder, Bernd; Nussenzweig, Michel C.; Liu, Kang; Geissmann, Frederic; Tangye, Stuart G.; Gros, Philippe; Sallusto, Federica; Bustamante, Jacinta; Casanova, Jean-Laurent Share Save 
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