Not logged inSRSF2 overexpression induces transcription-/replication-dependent DNA double-strand breaks and interferes with DNA repair pathways to promote lung tumor progression
Khalife, Manal; Jia, Tao; Caron, Pierre; Shreim, Amani; Genoux, Aurelie; Cristini, Agnese; Pucciarelli, Amelie; Leverve, Marie; Lepeltier, Nina; Garcia-Rodriguez, Nestor; Dalonneau, Fabien; Ramachandran, Shaliny; Fernandez Martinez, Lara; Marcion, Guillaume; Lemaitre, Nicolas; Brambilla, Elisabeth; Garrido, Carmen; Hammond, Ester M.; Huertas, Pablo; Gazzeri, Sylvie; Sordet, Olivier; Eymin, Beatrice .png)
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SaveSomatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancerMalchers, Florian; Nogova, Lucia; van Attekum, Martijn H. A.; Maas, Lukas; Braegelmann, Johannes; Bartenhagen, Christoph; Girard, Luc; Bosco, Graziella; Dahmen, Ilona; Michels, Sebastian; Weeden, Clare E.; Scheel, Andreas H.; Meder, Lydia; Golfmann, Kristina; Schuldt, Philipp; Siemanowski, Janna; Rehker, Jan; Merkelbach-Bruse, Sabine; Menon, Roopika; Gautschi, Oliver; Heuckmann, Johannes M.; Brambilla, Elisabeth; Asselin-Labat, Marie-Liesse; Persigehl, Thorsten; Minna, John D.; Walczak, Henning; Ullrich, Roland T.; Fischer, Matthias; Reinhardt, Hans Christian; Wolf, Juergen; Buettner, Reinhard; Peifer, Martin; George, Julie; Thomas, Roman K. Share Save Share Save VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loop (vol 38, pg 1050, 2018)Boudria, Asma; Abou Faycal, Cherine; Jia, Tao; Gout, Stephanie; Keramidas, Michelle; Didier, Chloe; Lemaitre, Nicolas; Manet, Sandra; Coll, Jean-Luc; Toffart, Anne-Claire; Moro-Sibilot, Denis; Albiges-Rizo, Corinne; Josserand, Veronique; Faurobert, Eva; Brambilla, Christian; Brambilla, Elisabeth; Gazzeri, Sylvie; Eymin, Beatrice Share Save Share Save Share Save Share Save Share Save Share Save Needlestack: an ultra-sensitive variant caller for multi-sample next generation sequencing dataDelhomme, Tiffany M.; Avogbe, Patrice H.; Gabriel, Aurelie A. G.; Alcala, Nicolas; Leblay, Noemie; Voegele, Catherine; Vallee, Maxime; Chopard, Priscilia; Chabrier, Amelie; Abedi-Ardekani, Behnoush; Gaborieau, Valerie; Holcatova, Ivana; Janout, Vladimir; Foretova, Lenka; Milosavljevic, Sasa; Zaridze, David; Mukeriya, Anush; Brambilla, Elisabeth; Brennan, Paul; Scelo, Ghislaine; Fernandez-Cuesta, Lynnette; Byrnes, Graham; Calvez-Kelm, Florence L.; McKay, James D.; Foll, Matthieu Share Save A Rare Fusion of CLIP1 and ALK in a Case of Non-Small-Cell Lung Cancer With Neuroendocrine FeaturesPinsolle, Julian; Mondet, Julie; Duruisseaux, Michael; DAlnoncourt, Segolene; Magnat, Nelly; de Fraipont, Florence; Moro-Sibilot, Denis; Toffart, Anne-Claire; Brambilla, Elisabeth; McLeer-Florin, Anne Share Save Integrative and comparative genomic analyses identify clinically relevant pulmonary carcinoid groups and unveil the supra-carcinoidsAlcala, N.; Leblay, N.; Gabriel, A. A. G.; Mangiante, L.; Hervas, D.; Giffon, T.; Sertier, A. S.; Ferrari, A.; Derks, J.; Ghantous, A.; Delhomme, T. M.; Chabrier, A.; Cuenin, C.; Abedi-Ardekani, B.; Boland, A.; Olaso, R.; Meyer, V; Altmuller, J.; Le Calvez-Kelm, F.; Durand, G.; Voegele, C.; Boyault, S.; Moonen, L.; Lemaitre, N.; Lorimier, P.; Toffart, A. C.; Soltermann, A.; Clement, J. H.; Saenger, J.; Field, J. K.; Brevet, M.; Blanc-Fournier, C.; Galateau-Salle, F.; Le Stang, N.; Russell, P. A.; Wright, G.; Sozzi, G.; Pastorino, U.; Lacomme, S.; Vignaud, J. M.; Hofman, V; Hofman, P.; Brustugun, O. T.; Lund-Iversen, M.; de Montpreville, V. Thomas; Muscarella, L. A.; Graziano, P.; Popper, H.; Stojsic, J.; Deleuze, J. F.; Herceg, Z.; Viari, A.; Nuernberg, P.; Pelosi, G.; Dingemans, A. M. C.; Milione, M.; Roz, L.; Brcic, L.; Volante, M.; Papotti, M. G.; Caux, C.; Sandoval, J.; Hernandez-Vargas, H.; Brambilla, E.; Speel, E. J. M.; Girard, N.; Lantuejoul, S.; McKay, J. D.; Foll, M.; Fernandez-Cuesta, L. Share Save LACE-Bio: Validation of Predictive and/or Prognostic Immunohistochemistry/ Histochemistry-based Biomarkers in Resected Non-small-cell Lung CancerSeymour, Lesley; Le Teuff, Gwenael; Brambilla, Elisabeth; Shepherd, Frances A.; Soria, Jean-Charles; Kratzke, Robert; Graziano, Stephen; Douillard, Jean-Yves; Rosell, Rafael; Reiman, Anthony; Lacas, Benjamin; Lueza, Beranger; Aviel-Ronen, Sarit; McLeer, Anne; Le Chevalier, Thierry; Pirker, Robert; Filipits, Martin; Dunant, Ariane; Pignon, Jean-Pierre; Tsao, Ming-Sound Share Save A common classification framework for neuroendocrine neoplasms: an International Agency for Research on Cancer (IARC) and World Health Organization (WHO) expert consensus proposalRindi, Guido; Klimstra, David S.; Abedi-Ardekani, Behnoush; Asa, Sylvia L.; Bosman, Frederik T.; Brambilla, Elisabeth; Busam, Klaus J.; de Krijger, Ronald R.; Dietel, Manfred; El-Naggar, Adel K.; Fernandez-Cuesta, Lynnette; Kloeppel, Guenter; McCluggage, W. Glenn; Moch, Holger; Ohgaki, Hiroko; Rakha, Emad A.; Reed, Nicholas S.; Rous, Brian A.; Sasano, Hironobu; Scarpa, Aldo; Scoazec, Jean-Yves; Travis, William D.; Tallini, Giovanni; Trouillas, Jacqueline; van Krieken, J. Han; Cree, Ian A. Share Save Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysisDuruisseaux, Michael; Martinez-Cardus, Anna; Calleja-Cervantes, Maria E.; Moran, Sebastian; Castro de Moura, Manuel; Davalos, Veronica; Pineyro, David; Sanchez-Cespedes, Montse; Girard, Nicolas; Brevet, Marie; Giroux-Leprieur, Etienne; Dumenil, Coraline; Pradotto, Monica; Bironzo, Paolo; Capelletto, Enrica; Novello, Silvia; Cortot, Alexis; Copin, Marie-Christine; Karachaliou, Niki; Gonzalez-Cao, Maria; Peralta, Sergio; Montuenga, Luis M.; Gil-Bazo, Ignacio; Baraibar, Iosune; Lozano, Maria D.; Varela, Mar; Ruffinelli, Jose C.; Palmero, Ramon; Nadal, Ernest; Moran, Teresa; Perez, Lidia; Ramos, Immaculada; Xiao, Qingyang; Fernandez, Agustin F.; Fraga, Mario F.; Gut, Marta; Gut, Ivo; Teixido, Cristina; Vilarino, Noelia; Prat, Aleix; Reguart, Noemi; Benito, Amparo; Garrido, Pilar; Barragan, Isabel; Emile, Jean-Francois; Rosell, Rafael; Brambilla, Elisabeth; Esteller, Manel Share Save VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a β1 integrin/VEGFR autocrine loopBoudria, Asma; Abou Faycal, Cherine; Jia, Tao; Gout, Stephanie; Keramidas, Michelle; Didier, Chloe; Lemaitre, Nicolas; Manet, Sandra; Coll, Jean-Luc; Toffart, Anne-Claire; Moro-Sibilot, Denis; Albiges-Rizo, Corinne; Josserand, Veronique; Faurobert, Eva; Brambilla, Christian; Brambilla, Elisabeth; Gazzeri, Sylvie; Eymin, Beatrice Share Save Multi-omics comparative analyses of pulmonary typical carcinoids, atypical carcinoids, and large-cell neuroendocrine carcinomaLeblay, Noemie; Alcala, Nicolas; Marin, David Hervas; Delhomme, Tiffany M.; Giffon, Theo; Ghantous, Akram; Chabrier, Amelie; Cuenin, Cyrille; Altmueller, Janine; Durand, Geoffroy; Voegele, Catherine; Lorimier, Philippe; Toffart, Anne-Claire; Derks, Jules; Brustugun, Odd Terje; Clement, Joachim H.; Saenger, Joerg; Field, John K.; Soltermann, Alex; Wright, Gavin M.; Roz, Luca; Muscarella, Lucia Anna; Graziano, Paolo; Herceg, Zdenko; Speel, Ernst-Jan; Nuernberg, Peter; McKay, James; Girard, Nicolas; Lantuejoul, Sylvie; Sandoval, Juan; Brambilla, Elisabeth; Foll, Matthieu; Fernandez-Cuesta, Lynnette Share Save Genome-wide copy number analyses of samples from LACE-Bio project identify novel prognostic and predictive markers in early stage non-small cell lung cancerRotolo, Federico; Zhu, Chang-Qi; Brambilla, Elisabeth; Graziano, Stephen L.; Olaussen, Ken; Le-Chevalier, Thierry; Pignon, Jean-Pierre; Kratzke, Robert; Soria, Jean-Charles; Shepherd, Frances A.; Seymour, Lesley; Michiels, Stefan; Tsao, Ming-Sound Share Save The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinomaAbou Faycal, Cherine; Brambilla, Elisabeth; Agorreta, Jackeline; Lepeltier, Nina; Jacquet, Thibault; Lemaitre, Nicolas; Emadali, Anouk; Lucas, Anthony; Lacal, Pedro M.; Montuenga, Luis; Pio, Ruben; Gazzeri, Sylvie; Eymin, Beatrice Share Save Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumorsGeorge, Julie; Walter, Vonn; Peifer, Martin; Alexandrov, Ludmil B.; Seidel, Danila; Leenders, Frauke; Maas, Lukas; Mueller, Christian; Dahmen, Ilona; Delhomme, Tiffany M.; Ardin, Maude; Leblay, Noemie; Byrnes, Graham; Sun, Ruping; De Reynies, Aurelien; McLeer-Florin, Anne; Bosco, Graziella; Malchers, Florian; Menon, Roopika; Altmuller, Janine; Becker, Christian; Nurnberg, Peter; Achter, Viktor; Lang, Ulrich; Schneider, Peter M.; Bogus, Magdalena; Soloway, Matthew G.; Wilkerson, Matthew D.; Cun, Yupeng; McKay, James D.; Moro-Sibilot, Denis; Brambilla, Christian G.; Lantuejoul, Sylvie; Lemaitre, Nicolas; Soltermann, Alex; Weder, Walter; Tischler, Verena; Brustugun, Odd Terje; Lund-Iversen, Marius; Helland, Aslaug; Solberg, Steinar; Ansen, Sascha; Wright, Gavin; Solomon, Benjamin; Roz, Luca; Pastorino, Ugo; Petersen, Iver; Clement, Joachim H.; Saenger, Jorg; Wolf, Jurgen; Vingron, Martin; Zander, Thomas; Perner, Sven; Travis, William D.; Haas, Stefan A.; Olivier, Magali; Foll, Matthieu; Buettner, Reinhard; Hayes, David Neil; Brambilla, Elisabeth; Fernandez-Cuesta, Lynnette; Thomas, Roman K. 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