arrow
Back
J

Jeffrey L. Brodsky

department of biological sciences

79H-index
394Paper Count
2.5WCitation Count
Published Papers 196
Publication Date
Targeting HDAC and proteostasis to eradicate quiescent cancer cells
err2026-08-13
err0
errOAAI
errQi Jiang; Michelle Ertel; Austin Arrigo; Amjad Hijazzi; Sara Sannino; Jennifer L. Goeckeler-Fried; April Sagan; Ian Beddows; Betsy Ann Varghese; Daniel D. Brown; Wayne Stallaert; Adrian Lee; Amanda M. Clark; Hui Shen; Jeffrey L. Brodsky; Hatice U. Osmanbeyoglu; Ronald J. Buckanovich
errShare
errSave
Regulated degradation of KCC2, a potassium-chloride co-transporter required for synaptic transmission and neurodevelopment
err2026-01-22
err0
PREAI
errKok, Morgan; Aizenman, Elias; Guerriero, Christopher J.; Brodsky, Jeffrey L.
errShare
errSave
Reconstitution of CFTR ubiquitination identifies lysine-420 as a regulator of cell surface residence and current
err2025-12-01
err0
errOAAI
errGoeckeler-Fried, Jennifer L.; Zeng, Xuemei; Hong, Jeong S.; Joshi, Disha; Yang, Zhengrong; Jiang, Fan; Kappes, John C.; Sorscher, Eric J.; Brodsky, Jeffrey L.
errShare
errSave
Thyroidal expression of ER molecular chaperone GRP170 is required for efficient TSH-mediated thyroid hormone synthesis
err2025-09-09
err0
PREAI
errZhang, Xiaohan; Young, Crystal; Liao, Xiao-Hui; Refetoff, Samuel; Mutchler, Stephanie M.; Brodsky, Jeffrey L.; Buck, Teresa M.; Arvan, Peter
errShare
errSave
Excess dietary sodium restores electrolyte and water homeostasis caused by loss of the endoplasmic reticulum molecular chaperone, GRP170, in the mouse nephron
err2025-02-01
err0
PREAI
errPorter, Aidan W.; Vorndran, Hannah E.; Marciszyn, Allison; Mutchler, Stephanie M.; Subramanya, Arohan R.; Kleyman, Thomas R.; Hendershot, Linda M.; Brodsky, Jeffrey L.; Buck, Teresa M.
errShare
errSave
Identification of polycystin 2 missense mutants targeted for endoplasmic reticulum-associated degradation
err2025-02-01
err0
PREAI
errGuerriero, Christopher J.; Carattino, Marcelo D.; Sharp, Katherine G.; Kantz, Luke J.; Gresko, Nikolay P.; Caplan, Michael J.; Brodsky, Jeffrey L.
errShare
errSave
FITM2 deficiency results in ER lipid accumulation, ER stress, and reduced apolipoprotein B lipidation and VLDL triglyceride secretion in vitro and in mouse liver
err2024-12-01
err0
errOAAI
errWang, Haizhen; Nikain, Cyrus; Fortounas, Konstantinos I.; Amengual, Jaume; Tufanli, Ozlem; La Forest, Maxwell; Yu, Yong; Wang, Meng C.; Watts, Russell; Lehner, Richard; Qiu, Yunping; Cai, Min; Kurland, Irwin J.; Goldberg, Ira J.; Rajan, Sujith; Hussain, M. Mahmood; Brodsky, Jeffrey L.; Fisher, Edward A.
errShare
errSave
Characterization of hyperactive mutations in the renal potassium channel ROMK uncovers unique effects on channel biogenesis and ion conductance
err2024-09-01
err1
errOAAI
errNguyen, Nga H.; Sheng, Shaohu; Banerjee, Anupam; Guerriero, Christopher J.; Chen, Jingxin; Wang, Xueqi; Mackie, Timothy D.; Welling, Paul A.; Kleyman, Thomas R.; Bahar, Ivet; Carlson, Anne E.; Brodsky, Jeffrey L.
errShare
errSave
The emerging role of fat-inducing transcript 2 in endoplasmic reticulum proteostasis and lipoprotein biogenesis
err2024-08-22
err0
PREAI
errBrodsky, Jeffrey L.; Iyer, Anuradha; Fortounas, Konstantinos I.; Fisher, Edward A.
errShare
errSave
Current insights and assumptions on α-synuclein in Lewy body disease
err2024-08-14
err0
errOAAI
errLeak, Rehana K.; Clark, Rachel N.; Abbas, Muslim; Xu, Fei; Brodsky, Jeffrey L.; Chen, Jun; Hu, Xiaoming; Luk, Kelvin C.
errShare
errSave
Optimization of the fluorogen-activating protein tag for quantitative protein trafficking and colocalization studies in S. cerevisiae
err2024-07-01
err0
PREAI
errOppenheimer, Katherine G.; Hager, Natalie A.; McAtee, Ceara K.; Filiztekin, Elif; Shang, Chaowei; Warnick, Justina A.; Bruchez, Marcel P.; Brodsky, Jeffrey L.; Prosser, Derek C.; Kwiatkowski, Adam, V; O'Donnell, Allyson F.
errShare
errSave
Loss of Grp170 results in catastrophic disruption of endoplasmic reticulum function
err2024-04-01
err1
errOAAI
errMann, Melissa J.; Melendez-Suchi, Chris; Vorndran, Hannah E.; Sukhoplyasova, Maria; Flory, Ashley R.; Irvine, Mary Carson; Iyer, Anuradha R.; Guerriero, Christopher J.; Brodsky, Jeffrey L.; Hendershot, Linda M.; Buck, Teresa M.
errShare
errSave
A new combinatorial therapy that synergistically targets the NuRD complex and proteostasis to eradicate quiescent ovarian cancer cells
err2024-03-22
err0
PREAI
errJiang, Qi; Ertel, Michelle; Panesso-Gomez, Santiago; Sannino, Sara; Sagan, April; Cole, Alexander J.; McGonigal, Stacy C.; Varghese, Betsy Ann; Stallaert, Wayne; Brodsky, Jeffrey L.; Osmanbeyoglu, Hatice U.; Buckanovich, Ronald J.
errShare
errSave
The expression system influences stability, maturation efficiency, and oligomeric properties of the potassium-chloride co-transporter KCC2
err2024-03-01
err4
PREAI
errKok, Morgan; -Scott, Karen Hartnett; Happe, Cassandra L.; Macdonald, Matthew L.; Aizenman, Elias; Brodsky, Jeffrey L.
errShare
errSave
J-domain proteins: From molecular mechanisms to diseases
err2024-02-01
err7
errOAAI
errMarszalek, Jaroslaw; De Los Rios, Paolo; Cyr, Douglas; Mayer, Matthias P.; Adupa, Vasista; Andreasson, Claes; Blatch, Gregory L.; Braun, Janice E. A.; Brodsky, Jeffrey L.; Bukau, Bernd; Chapple, J. Paul; Conz, Charlotte; Dementin, Sebastien; Genevaux, Pierre; Genest, Olivier; Goloubinoff, Pierre; Gestwicki, Jason; Hammond, Colin M.; Hines, Justin K.; Ishikawa, Koji; Joachimiak, Lukasz A.; Kirstein, Janine; Liberek, Krzysztof; Mokranjac, Dejana; Nillegoda, Nadinath; Ramos, Carlos H. I.; Rebeaud, Mathieu; Ron, David; Rospert, Sabine; Sahi, Chandan; Shalgi, Reut; Tomiczek, Bartlomiej; Ushioda, Ryo; Ustyantseva, Elizaveta; Ye, Yihong; Zylicz, Maciej; Kampinga, Harm H.
errShare
errSave
Genome mining yields putative disease-associated ROMK variants with distinct defects
err2023-11-13
err2
errOAAI
errNguyen, Nga H.; Sarangi, Srikant; Mcchesney, Erin M.; Sheng, Shaohu; Durrant, Jacob D.; Porter, Aidan W.; Kleyman, Thomas R.; Pitluk, Zachary W.; Brodsky, Jeffrey L.
errShare
errSave