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J

Jonathan S. Weissman

Whitehead Institute for Biomedical Research

157H-index
550Paper Count
12.0WCitation Count
Published Papers 182
Publication Date
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Reply to: Artefacts in single-cell mtDNA analyses misinform phylogenies
errNature
IF48.5
err2026-08-19
err0
PREAI
errChen Weng; Jonathan S. Weissman; Vijay G. Sankaran
errShare
errSave
Atlas of lysosomal aging reveals a metabolite signature shared with lysosomal storage disorders
errScience
IF45.8
err2026-07-30
err0
PREAI
errAnna M. Puszynska; Thao P. Nguyen; Andrew L. Cangelosi; Andrea Armani; Justin M. Roberts; Kristin A. Singh; James C. Cameron; Tenzin Tseyang; Grace Y. Liu; Steven Lai; Hans-Georg Sprenger; Jason Yang; William N. Colgan; Jibril F. Kedir; Kathrin M. Kajderowicz; Theodore K. Esantsi; Yuancheng Ryan Lu; Millenia Waite; Tenzin Kunchok; Caroline A. Lewis; Fabian Schulte; George W. Bell; David M. Sabatini; Jonathan S. Weissman
errShare
errSave
Expanding the human proteome with microproteins and peptideins
errNature
IF48.5
err2026-05-01
err0
PREAI
errDeutsch, Eric W.; Kok, Leron W.; Mudge, Jonathan M.; Valls, Cristian F.; Jungreis, Irwin; Ruiz-Orera, Jorge; Sun, Zhi; Kusebauch, Ulrike; Fierro-Monti, Ivo; Abelin, Jennifer G.; Alba, M. Mar; Aspden, Julie L.; Bandyopadhyay, Sreejan; Banerjee, Kaushik; Baranov, Pavel V.; Bazzini, Ariel A.; Bourassa, Francis; Bruford, Elspeth A.; Calviello, Lorenzo; Carr, Steven A.; Carvunis, Anne-Ruxandra; Chothani, Sonia; Clauwaert, Jim; Dean, Kellie; Faridi, Pouya; Frankish, Adam; Goodale, Amy; Green, Thomas; Hubner, Norbert; Ingolia, Nicholas T.; Kellis, Manolis; Magrane, Michele; Martin, Maria Jesus; Martinez, Thomas F.; Menschaert, Gerben; Ohler, Uwe; Orchard, Sandra; Potter, Alisa; Rackham, Owen J. L.; Rees, Matthew G.; Root, David E.; Roth, Jennifer A.; Roucou, Xavier; Sialana, Fernando J.; Slavoff, Sarah A.; Swirski, Michal I.; Tierney, Jack A. S.; Trifiro, Felix-Antoine; Valen, Eivind; Vasylieva, Valeriia; Wacholder, Aaron; Wang, Shengbo; Wang, Li; Weissman, Jonathan S.; Wu, Wei; Choudhary, Jyoti S.; Bassani-Sternberg, Michal; Vizcaino, Juan Antonio; Ternette, Nicola; Brunet, Marie A.; Moritz, Robert L.; Prensner, John R.; van Heesch, Sebastiaan
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The GENEVA platform models tumor mosaicism to reveal variations of responses to KRAS inhibitors and identify improved drug combinations
errNature Cancer
IF28.5
err2026-02-24
err0
errOAAI
errJohnny X. Yu; Jung Min Suh; Katerina D. Popova; Kristle Garcia; Tanvi Joshi; Bruce Culbertson; Jessica B. Spinelli; Vishvak Subramanyam; Kevin Lou; Trey Charbonneau; Kevan M. Shokat; Jonathan Weissman; Hani Goodarzi
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errSave
Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation
errScience
IF45.8
err2026-02-12
err0
PREAI
errMohamed A. El-Brolosy; Atharv Oak; An T. Hoang; Yassine Damergi; André Fischer; Reuben A. Saunders; Jingchuan Luo; Amer Balabaki; Jeremy Guez; Troy W. Whitfield; Seth R. Goldman; Arash Latifkar; Yuancheng Ryan Lu; Didier Y. R. Stainier; Konrad J. Karczewski; Olivia Corradin; Jonathan S. Weissman
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errSave
Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation
errCell
IF42.5
err2025-08-27
err0
errOAAI
errJingchuan Luo; Stuti Khandwala; Jingjie Hu; Song-Yi Lee; Kelsey L. Hickey; Zebulon G. Levine; J. Wade Harper; Alice Y. Ting; Jonathan S. Weissman
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errSave
High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer
errScience
IF45.8
err2025-07-24
err0
PREAI
errLuke W. Koblan; Kathryn E. Yost; Pu Zheng; William N. Colgan; Matthew G. Jones; Dian Yang; Arhan Kumar; Jaspreet Sandhu; Alexandra Schnell; Dawei Sun; Can Ergen; Reuben A. Saunders; Xiaowei Zhuang; William E. Allen; Nir Yosef; Jonathan S. Weissman
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errSave
Shaping the composition of the mitochondrial outer membrane
errNature Cell Biology
IF19.1
err2025-06-16
err0
PREAI
errGayathri Muthukumar; Jonathan S. Weissman
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errSave
Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue
errCell
IF42.5
err2025-06-12
err0
errOAAI
errReuben A. Saunders; William E. Allen; Xingjie Pan; Jaspreet Sandhu; Jiaqi Lu; Thomas K. Lau; Karina Smolyar; Zuri A. Sullivan; Catherine Dulac; Jonathan S. Weissman; Xiaowei Zhuang
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errSave
Transcriptome-wide analysis of differential expression in perturbation atlases
errNATURE GENETICS
IF0
err2025-04-21
err1
PREAI
errNadig, Ajay; Replogle, Joseph M.; Pogson, Angela N.; Murthy, Mukundh; McCarroll, Steven A.; Weissman, Jonathan S.; Robinson, Elise B.; O'Connor, Luke J.
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errSave
Spatiotemporal modeling of molecular holograms (vol 187, pg 7351, 2024)
errCELL
IF42.5
err2025-03-01
err0
errOAAI
errQiu, Xiaojie; Zhu, Daniel Y.; Lu, Yifan; Yao, Jiajun; Jing, Zehua; Min(Joseph), Kyung Hoi; Cheng, Mengnan; Pan, Hailin; Zuo, Lulu; King, Samuel; Fang, Qi; Zheng, Huiwen; Wang, Mingyue; Wang, Shuai; Zhang, Qingquan; Yu, Sichao; Liao, Sha; Liu, Chao; Wu, Xinchao; Lai, Yiwei; Hao, Shijie; Zhang, Zhewei; Wu, Liang; Zhang, Yong; Li, Mei; Tu, Zhencheng; Lin, Jinpei; Yang, Zhuoxuan; Li, Yuxiang; Gu, Ying; Ellison, David; Lu, Yuancheng Ryan; Hu, Qinan; Hu, Yuhui; Chen, Ao; Liu, Longqi; Weissman, Jonathan S.; Ma, Jiayi; Xu, Xun; Liu, Shiping; Bai, Yinqi
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errSave
Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress
errDEVELOPMENTAL CELL
IF8.7
err2024-08-01
err1
errOAAI
errDo, Brian T.; Hsu, Peggy P.; Vermeulen, Sidney Y.; Wang, Zhishan; Hirz, Taghreed; Abbott, Keene L.; Aziz, Najihah; Replogle, Joseph M.; Bjelosevic, Stefan; Paolino, Jonathan; Nelson, Samantha A.; Block, Samuel; Darnell, Alicia M.; Ferreira, Raphael; Zhang, Hanyu; Milosevic, Jelena; Schmidt, Daniel R.; Chidley, Christopher; Harris, Isaac S.; Weissman, Jonathan S.; Pikman, Yana; Stegmaier, Kimberly; Cheloufi, Sihem; Su, Xiaofeng A.; Sykes, David B.; Vander Heiden, Matthew G.
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CRISPRi screens identify the lncRNA, LOUP , as a multifunctional locus regulating macrophage differentiation and inflammatory signaling
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-05-23
err4
errOAAI
errHalasz, Haley; Malekos, Eric; Covarrubias, Sergio; Yitiz, Samira; Montano, Christy; Sudek, Lisa; Katzman, Sol; Liu, S. John; Horlbeck, Max A.; Namvar, Leila; Weissman, Jonathan S.; Carpenter, Susan
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errSave
CRISPR technologies for genome, epigenome and transcriptome editing (FEB, 10.1038/s41580-023-00697-6, 2024)
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2024-05-13
err0
errOAAI
errVilliger, Lukas; Joung, Julia; Koblan, Luke; Weissman, Jonathan; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
errShare
errSave
Dissecting and quantifying pancreatic cancer plasticity using single-cell multiomics, lineage tracing and functional genomics reveals novel mediators of therapy resistance
errCANCER RESEARCH
IF16.6
err2024-04-05
err0
PREAI
errMehta, Arnav; Bi, Lynn; Yeramosu, Deepika; Bogaev, Michael; Jankowiak, Martin; Collins, Abigail; Al'Khafaji, Aziz; Parikh, Milan; Babadi, Mehrtash; Evans, Kyle; Bloemendal, Alex; Kunnes, Russell; Schwartz, Marc; Munson, Glen; Donnard, Elisa; Jones, Thouis R.; Stanger, Ben Z.; Shendure, Jay; Weissman, Jonathan; Ting, David T.; Aguirre, Andrew; Hacohen, Nir; Pe'er, Dana; Lander, Eric S.
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errSave
Triaging of α- helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology
errMOLECULAR CELL
IF16.6
err2024-03-01
err1
errOAAI
errMuthukumar, Gayathri; Stevens, Taylor A.; Inglis, Alison J.; Esantsi, Theodore K.; Saunders, Reuben A.; Schulte, Fabian; Voorhees, Rebecca M.; Guna, Alina; Weissman, Jonathan S.
errShare
errSave
CRISPR technologies for genome, epigenome and transcriptome editing
errNATURE REVIEWS MOLECULAR CELL BIOLOGY
IF90.2
err2024-02-02
err34
PREAI
errVilliger, Lukas; Joung, Julia; Koblan, Luke; Weissman, Jonathan; Abudayyeh, Omar O.; Gootenberg, Jonathan S.
errShare
errSave
Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning
errNATURE BIOTECHNOLOGY
IF41.7
err2023-10-18
err0
errOAAI
errKoblan, Luke W.; Arbab, Mandana; Shen, Max W.; Hussmann, Jeffrey A.; Anzalone, Andrew V.; Doman, Jordan L.; Newby, Gregory A.; Yang, Dian; Mok, Beverly; Replogle, Joseph M.; Xu, Albert; Sisley, Tyler A.; Weissman, Jonathan S.; Adamson, Britt; Liu, David R.
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errSave
Coupled protein quality control during nonsense-mediated mRNA decay
errJOURNAL OF CELL SCIENCE
IF3.6
err2023-05-23
err12
errOAAI
errInglis, Alison J.; Guna, Alina; Galvez-Merchan, Angel; Pal, Akshaye; Esantsi, Theodore K.; Keys, Heather R.; Frenkel, Evgeni M.; Oania, Robert; Weissman, Jonathan S.; Voorhees, Rebecca M.
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errSave
Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity
errNUCLEIC ACIDS RESEARCH
IF13.1
err2023-05-05
err7
errOAAI
errShe, Richard; Luo, Jingchuan; Weissman, Jonathan S.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Marc W. Kirschner
H-index: 169 · Papers: 526
Z
Zena Werb
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