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J

John A. Chiorini

National Institute of Dental and Craniofacial Research

60H-index
225Paper Count
1.3WCitation Count
Published Papers 104
Publication Date
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A Rare LAMP3 Gene Variant Drives Enhanced Epithelial Cell Apoptosis and Salivary Gland Dysfunction
errOral Diseases
IF2.9
err2026-05-05
err0
PREAI
errHitomi Ono-Minagi; Peter D. Burbelo; Natalie Atyeo; Sandra A. Afione; Changyu Zheng; John A. Chiorini
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Familial and genetic overlap between Sjögren’s disease and other autoimmune diseases
errFrontiers in Immunology
IF5.9
err2026-03-26
err0
errOAAI
errHO Hitomi Ono-Minagi; TO Takuma Ohnishi; NA Natalie Atyeo; KO Kentaro Okuno; PD Peter D. Burbelo; JA John A. Chiorini
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Improved Detection of Myositis-Specific Autoantibodies Using Luciferase Immunoprecipitation Systems Assay: Comparison with Line Blot and Conventional Immunoprecipitation
errArthritis & Rheumatology
IF10.9
err2026-02-23
err0
PREAI
errPeter D. Burbelo; Iago Pinal-Fernandez; Maria Casal-Dominguez; Xin Tian; Shijinqiu Gao; Neha Gupta; Eric Robbins; John A. Chiorini; Christopher A. Mecoli; Lisa Christopher-Stine; Livia Casciola-Rosen; Andrew Mammen; Sonye K. Danoff; Anthony F. Suffredini; Julio A. Huapaya
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Effect of Delayed Antiretroviral Therapy Initiation on Anti-CD4 Autoantibodies in Antiretroviral Therapy-Naïve People With HIV
errThe Journal of Infectious Diseases
IF0
err2026-01-01
err0
PREAI
errBrian P Epling, MD; Shweta Mistry, MS; Birgit Grund, PhD; Jason V Baker, MD; Carlos Brites, MD; Julien Gras, MD; Sandy Pillay, MBChB; Blessing Uche, RN; John A Chiorini, PhD; Andrea Lisco, MD; Peter D Burbelo, PhD; Irini Sereti, MD
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Investigation of Lysosome-Associated Membrane Protein 3 Highlights the Role of Lysosome in Pathophysiology and Treatment of Sjögren's Disease
errArthritis & Rheumatology
IF10.9
err2025-08-04
err0
PREAI
errHiroyuki Nakamura M.D., Ph.D.; Tsutomu Tanaka D.V.M., Ph.D.; Masayuki Noguchi M.D., Ph.D.; Tatsuya Atsumi M.D., Ph.D.; Blake M Warner D.D.S., Ph.D, M.P.H.; John A Chiorini Ph.D.
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Anti-Mi2 autoantibodies target PHD fingers of SP140L and TIF1γ, while anti-TIF1γ autoantibodies primarily bind TIF1γ outside the PHD region
errRHEUMATOLOGY
IF4.4
err2025-08-01
err0
PREAI
errPinal-Fernandez, Iago; Musai, Jon; Casal-Dominguez, Maria; Pak, Katherine; Kaplan, Mariana; Warner, Blake M.; Rider, Lisa G.; Aggarwal, Rohit; Oddis, Chester, V; Moghadam-Kia, Siamak; Garrabou, Gloria; Selva-O'Callaghan, Albert; Milisenda, Jose C.; Chiorini, John A.; Mammen, Andrew L.; Burbelo, Peter D.
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Quantification of autoantibodies using a luminescent profiling method in autoimmune interstitial lung disease
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-10-25
err0
errOAAI
errBurbelo, Peter D.; Huapaya, Julio A.; Khavandgar, Zohreh; Beach, Margaret; Pinal-Fernandez, Iago; Mammen, Andrew L.; Chiorini, John A.; Farhadi, Payam Noroozi; Miller, Frederick W.; Schiffenbauer, Adam; Sarkar, Kakali; Warner, Blake M.; Rider, Lisa G.
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Amplified Type I Interferon Response in Sjögren's Disease via Ectopic Toll-Like Receptor 7 Expression in Salivary Gland Epithelial Cells Induced by Lysosome-Associated Membrane Protein 3
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2024-06-04
err2
errOAAI
errNakamura, Hiroyuki; Tanaka, Tsutomu; Zheng, Changyu; Afione, Sandra A.; Atsumi, Tatsuya; Noguchi, Masayuki; Oliveira, Fabiola Reis; Motta, Ana Carolina F.; Chahud, Fernando; Rocha, Eduardo M.; Warner, Blake M.; Chiorini, John A.
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Unique immune cells in oral cavity are critical for enteric virus pathogenesis
errJOURNAL OF IMMUNOLOGY
IF3.4
err2024-05-01
err0
PREAI
errBrogden, Graham; Labayo, Hannah; Salazar, Emanuel; Atyeo, Natalie; Gribonika, Inta; Belkaid, Yasmine; Chiorini, John; Altan-Bonnet, Gregoire; Altan-Bonnet, Nihal
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Salivary Glands and Viral Pathogenesis
errJOURNAL OF DENTAL RESEARCH
IF5.9
err2024-02-12
err2
PREAI
errAtyeo, N.; Maldonado, J. O.; Warner, B. M.; Chiorini, J. A.
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Evidence of a Sjögren's disease-like phenotype following COVID-19 in mice and humans
errJCI INSIGHT
IF6.1
err2023-12-22
err6
errOAAI
errShen, Yiran; Voigt, Alexandria; Goranova, Laura; Abed, Mehdi; Kleiner, David E.; Maldonado, Jose O.; Beach, Margaret; Pelayo, Eileen; Chiorini, John A.; Craft, William F.; Ostrov, David A.; Ramiya, Vijay; Sukumaran, Sukesh; Brown, Ashley N.; Hanrahan, Kaley C.; Tuanyok, Apichai; Warner, Blake M.; Nguyen, Cuong Q.
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Structural and antigenic characterization of the avian adeno-associated virus capsid
errJOURNAL OF VIROLOGY
IF3.8
err2023-10-31
err5
errOAAI
errHsi, Jane; Mietzsch, Mario; Chipman, Paul; Afione, Sandra; Zeher, Allison; Huang, Rick; Chiorini, John; Mckenna, Robert
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errSave
Lysosome-Associated Membrane Protein 3 Induces Lysosome-Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjogren's Disease
errARTHRITIS & RHEUMATOLOGY
IF10.9
err2023-07-27
err8
errOAAI
errNakamura, Hiroyuki; Tanaka, Tsutomu; Zheng, Changyu; Afione, Sandra A.; Warner, Blake M.; Noguchi, Masayuki; Atsumi, Tatsuya; Chiorini, John A.
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Inhibition of Janus Kinase pathway corrects IFN-driven inflammation and epithelial dysfunction in Sjogren's disease
errJOURNAL OF IMMUNOLOGY
IF3.4
err2023-05-01
err0
errOAAI
errGupta, Sarthak; Yamada, Eiko; Nakamura, Hiroyuki; Khavandgar, Zohreh; Martin, Daniel; Tandon, Mayank; Alevizos, Ilias; Jang, Shyh-Ing; Perez, Paola; Dominick, Kalie; Pranzatelli, Thomas; Baer, Alan; Chiorini, John; Warner, Blake
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Inhibition of PrKX, a novel protein kinase, and the cyclic AMP-dependent protein kinase PKA by the regulatory proteins of adeno-associated virus type 2
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err58
errOAAI
errChiorini, JA; Zimmermann, B; Yang, L; Smith, RH; Ahearn, A; Herberg, F; Kotin, RM
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LAMP3 transfer via extracellular particles induces apoptosis in Sjogren's disease
errSCIENTIFIC REPORTS
IF3.9
err2023-02-14
err2
errOAAI
errTanaka, Tsutomu; Nakamura, Hiroyuki; Tran, Duy T.; Warner, Blake M.; Wang, Yan; Atsumi, Tatsuya; Noguchi, Masayuki; Chiorini, John A.
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errSave
Correction of LAMP3-associated salivary gland hypofunction by aquaporin gene therapy
errSCIENTIFIC REPORTS
IF3.9
err2022-11-03
err11
errOAAI
errNakamura, Hiroyuki; Tanaka, Tsutomu; Zheng, Changyu; Afione, Sandra A.; Warner, Blake M.; Noguchi, Masayuki; Atsumi, Tatsuya; Chiorini, John A.
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errSave
Lysosomal exocytosis of HSP70 stimulates monocytic BMP6 expression in Sjogren's syndrome
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-03-15
err19
errOAAI
errMo, Ying-Qian; Nakamura, Hiroyuki; Tanaka, Tsutomu; Odani, Toshio; Perez, Paola; Ji, Youngmi; French, Benjamin N.; Pranzatelli, Thomas J. F.; Michael, Drew G.; Yin, Hongen; Chow, Susan S.; Khalaj, Maryam; Afione, Sandra A.; Zheng, Changyu; Oliveira, Fabiola Reis; Motta, Ana Carolina F.; Ribeiro-Silva, Alfredo; Rocha, Eduardo M.; Nguyen, Cuong Q.; Noguchi, Masayuki; Atsumi, Tatsuya; Warner, Blake M.; Chiorini, John A.
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Autoantibodies Against Proteins Previously Associated With Autoimmunity in Adult and Pediatric Patients With COVID-19 and Children With MIS-C
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-03-11
err23
errOAAI
errBurbelo, Peter D.; Castagnoli, Riccardo; Shimizu, Chisato; Delmonte, Ottavia M.; Dobbs, Kerry; Discepolo, Valentina; Lo Vecchio, Andrea; Guarino, Alfredo; Licciardi, Francesco; Ramenghi, Ugo; Rey-Jurado, Emma; Vial, Cecilia; Marseglia, Gian Luigi; Licari, Amelia; Montagna, Daniela; Rossi, Camillo; Sanchez, Gina A. Montealegre; Barron, Karyl; Warner, Blake M.; Chiorini, John A.; Espinosa, Yazmin; Noguera, Loreani; Dropulic, Lesia; Truong, Meng; Gerstbacher, Dana; Mato, Sayonara; Kanegaye, John; Tremoulet, Adriana H.; Eisenstein, Eli M.; Su, Helen C.; Imberti, Luisa; Poli, Maria Cecilia; Burns, Jane C.; Notarangelo, Luigi D.; Cohen, Jeffrey I.
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LAMP3 inhibits autophagy and contributes to cell death by lysosomal membrane permeabilization
errAUTOPHAGY
IF14.3
err2021-11-22
err49
errOAAI
errTanaka, Tsutomu; Warner, Blake M.; Michael, Drew G.; Nakamura, Hiroyuki; Odani, Toshio; Yin, Hongen; Atsumi, Tatsuya; Noguchi, Masayuki; Chiorini, John A.
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Research Directions

No research directions
Co-authors
Cooperation Journals
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Kenneth M. Yamada
H-index: 151 · Papers: 1.1K
M
Michael J. Welsh
H-index: 143 · Papers: 669
S
Sarah A. Teichmann
H-index: 141 · Papers: 677
P
Peter L. Choyke
H-index: 141 · Papers: 1.9K
G
GutkindJ.Silvio (J. Silvio Gutkind)
H-index: 140 · Papers: 1.3K
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