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α-Synuclein oligomers form by secondary nucleation Xu, Catherine K.; Meisl, Georg; Andrzejewska, Ewa A.; Krainer, Georg; Dear, Alexander J.; Castellana-Cruz, Marta; Turi, Soma; Edu, Irina A.; Vivacqua, Giorgio; Jacquat, Raphael P. B.; Arter, William E.; Spillantini, Maria Grazia; Vendruscolo, Michele; Linse, Sara; Knowles, Tuomas P. J. Share Save
Cleaved TMEM106B forms amyloid aggregates in central and peripheral nervous systems Bacioglu, Mehtap; Schweighauser, Manuel; Gray, Derrick; Lovestam, Sofia; Katsinelos, Taxiarchis; Quaegebeur, Annelies; van Swieten, John; Jaunmuktane, Zane; Davies, Stephen W.; Scheres, Sjors H. W.; Goedert, Michel; Ghetti, Bernardino; Spillantini, Maria Grazia Share Save
Meeting Summary of The NYO3 5th NO-Age/AD Meeting and the 1st Norway-UK Joint Meeting on Aging and Dementia: Recent Progress on the Mechanisms and Interventional Strategies Wang, He-Ling; Siow, Richard; Schmauck-Medina, Tomas; Zhang, Jianying; Sandset, Per Morten; Filshie, Clare; Lund, Oystein; Partridge, Linda; Bergersen, Linda Hildegard; Juel Rasmussen, Lene; Palikaras, Konstantinos; Sotiropoulos, Ioannis; Storm-Mathisen, Jon; Rubinsztein, David C.; Spillantini, Maria Grazia; De Zeeuw, Chris, I; Watne, Leiv Otto; Vyhnalek, Martin; Veverova, Katerina; Liang, Kristina Xiao; Tavernarakis, Nektarios; Bohr, Vilhelm A.; Yokote, Koutaro; Saarela, Janna; Nilsen, Hilde; Gonos, Efstathios S.; Scheibye-Knudsen, Morten; Chen, Guobing; Kato, Hisaya; Selbaek, Geir; Fladby, Tormod; Nilsson, Per; Simonsen, Anne; Aarsland, Dag; Lautrup, Sofie; Ottersen, Ole Petter; Cox, Lynne S.; Fang, Evandro F. Share Save
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy Yang, Yang; Garringer, Holly J.; Shi, Yang; Lovestam, Sofia; Peak-Chew, Sew; Zhang, Xianjun; Kotecha, Abhay; Bacioglu, Mehtap; Koto, Atsuo; Takao, Masaki; Spillantini, Maria Grazia; Ghetti, Bernardino; Vidal, Ruben; Murzin, Alexey G.; Scheres, Sjors H. W.; Goedert, Michel Share Save
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Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind placebo-controlled phase 1a trial Levin, Johannes; Sing, Nand; Melbourne, Sue; Morgan, Amber; Mariner, Carla; Spillantini, Maria Grazia; Wegrzynowicz, Michal; Dalley, Jeffrey W.; Langer, Simon; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Schmidt, Felix; Weckbecker, Daniel; Prager, Kai; Matthias, Torsten; Giese, Armin Share Save
Synapsin III gene silencing redeems alpha-synuclein transgenic mice from Parkinson's disease-like phenotype Faustini, Gaia; Longhena, Francesca; Masato, Anna; Bassareo, Valentina; Frau, Roberto; Klingstedt, Therese; Shirani, Hamid; Brembati, Viviana; Parrella, Edoardo; Vezzoli, Marika; Nilsson, K. Peter R.; Pizzi, Marina; Spillantini, Maria Grazia; Bubacco, Luigi; Bellucci, Arianna Share Save
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The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration Puigdellivol, Mar; Milde, Stefan; Vilalta, Anna; Cockram, Tom O. J.; Allendorf, David H.; Lee, Jeffrey Y.; Dundee, Jacob M.; Pampuscenko, Katryna; Borutaite, Vilmante; Nuthall, Hugh N.; Brelstaff, Jack H.; Spillantini, Maria Grazia; Brown, Guy C. Share Save
In Vivo 18F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy Malpetti, Maura; Kaalund, Sanne S.; Tsvetanov, Kamen A.; Rittman, Timothy; Briggs, Mayen; Allinson, Kieren S. J.; Passamonti, Luca; Holland, Negin; Jones, P. Simon; Fryer, Tim D.; Hong, Young T.; Kouli, Antonina; Bevan-Jones, W. Richard; Mak, Elijah; Savulich, George; Spillantini, Maria Grazia; Aigbirhio, Franklin, I; Williams-Gray, Caroline H.; O'Brien, John T.; Rowe, James B. Share Save
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CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice Calo, Laura; Hidari, Eric; Wegrzynowicz, Michal; Dalley, Jeffrey W.; Schneider, Bernard L.; Podgajna, Martyna; Anichtchik, Oleg; Carlson, Emma; Klenerman, David; Spillantini, Maria Grazia Share Save
Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models McMurray, Lindsay; Macdonald, Jennifer A.; Ramakrishnan, Nisha Kuzhuppilly; Zhao, Yanyan; Williamson, David W.; Tietz, Ole; Zhou, Xiaoyun; Kealey, Steven; Fagan, Steven G.; Smolek, Tomas; Cubinkova, Veronika; Zilka, Norbert; Spillantini, Maria Grazia; Tolkovsky, Aviva M.; Goedert, Michel; Aigbirhio, Franklin, I Share Save
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Alpha-synuclein/synapsin III pathological interplay boosts the motor response to methylphenidate Faustini, Gaia; Longhena, Francesca; Bruno, Agostino; Bono, Federica; Grigoletto, Jessica; La Via, Luca; Barbon, Alessandro; Casiraghi, Andrea; Straniero, Valentina; Valoti, Ermanno; Costantino, Gabriele; Benfenati, Fabio; Missale, Cristina; Pizzi, Marina; Spillantini, Maria Grazia; Bellucci, Arianna Share Save
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