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Robert J. Wechsler‐Reya

Herbert Irving Comprehensive Cancer Center

60H-index
483Paper Count
1.8WCitation Count
Published Papers 112
Publication Date
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Preservation and clonal behavior of extrachromosomal DNA in patient-derived xenograft models of childhood cancers
errGenome Medicine
IF11.2
err2026-05-28
err0
errOAAI
errRishaan Kenkre; Owen S. Chapman; Eugene Yui-Ching Chow; Jens Luebeck; Yan Yuen Lo; Megan Paul; Wenshu Zhang; Jill Mesirov; Vineet Bafna; Kevin Yip; Jon D. Larson; Robert J. Wechsler-Reya; Lukas Chavez
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errSave
Repurposing Thyroid Hormone to Improve Chemotherapy Outcome for Medulloblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errYang, Yijun; Ronsley, Rebecca; Leary, Sarah; Kilburn, Lindsay; Wechsler-Reya, Robert J.; Yang, Zeng-jie
errShare
errSave
HDAC inhibition enhances medulloblastoma immunogenicity and prolongs survival in preclinical models
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errChambers, Kendall R.; Masihi, Meher Beigi; Bloxham, Talia; Eisemann, Tanja; Koubourli, Daphne; Sajina, G. C.; Winick, Jacob; Tzaridis, Theophilos; Wechsler-Reya, Robert J.
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errSave
CD155 regulates tumor growth and immune evasion in diffuse midline glioma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errTzaridis, Theophilos; Fernandez, Ester Calvo; Eisemann, Tanja; Andrade, Augusto Faria; De Biagi-Junior, Carlos A. O.; Hope, Jennifer L.; Becher, Oren J.; Jabado, Nada; Larson, Jon D.; Bagchi, Anindya; Filbin, Mariella G.; Bradley, Lindam; Adams, Peter D.; Pavisic, Jovana; Wechsler-Reya, Robert J.
errShare
errSave
ONC206 inhibits tumor growth and is a potential novel therapeutic strategy for refractory medulloblastoma
errNEURO-ONCOLOGY
IF13.4
err2025-11-01
err0
errOAAI
errTzaridis, Theophilos; Liu, Jingbo; Allen, Joshua E.; Prabhu, Varun V.; Wechsler-Reya, Robert J.; Macdonald, Tobey
errShare
errSave
Case Report: Application of ex-vivo drug sensitivity testing to identify personalized treatment options for an adolescent with diffuse midline glioma
errFrontiers in Oncology
IF3.3
err2025-08-08
err0
errOAAI
errPhilip K. Tan; Timothy J. Martins; Pamela S. Becker; Robert J. Wechsler-Reya; John Ross Crawford
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errSave
Isocitrate dehydrogenase 1 primes group-3 medulloblastomas for cuproptosis
errCancer Cell
IF44.5
err2025-05-15
err0
PREAI
errDerek Dang; Akash Deogharkar; John McKolay; Kyle S. Smith; Pooja Panwalkar; Simon Hoffman; Wentao Tian; Sunjong Ji; Ana P. Azambuja; Siva Kumar Natarajan; Joanna Lum; Jill Bayliss; Katie Manzeck; Stefan R. Sweha; Erin Hamanishi; Matthew Pun; Diya Patel; Sagar Rau; Olamide Animasahun; Abhinav Achreja; Martin P. Ogrodzinski; Jutta Diessl; Jennifer Cotter; Debra Hawes; Fusheng Yang; Robert Doherty; Andrea T. Franson; Allison R. Hanaford; Charles G. Eberhart; Eric H. Raabe; Brent A. Orr; Robert J. Wechsler-Reya; Brandon Chen; Costas A. Lyssiotis; Yatrik M. Shah; Sophia Y. Lunt; Ruma Banerjee; Alexander R. Judkins; John R. Prensner; Carl Koschmann; Sebastian M. Waszak; Deepak Nagrath; Marcos Simoes-Costa; Paul A. Northcott; Sriram Venneti
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errSave
The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
errCELL DEATH AND DIFFERENTIATION
IF15.4
err2025-03-28
err0
errOAAI
errOhata, Yae; Ali, Mohamad M.; Tsubakihara, Yutaro; Itoh, Yuka; Rosen, Gabriela; Bergstrom, Tobias; Moren, Anita; Golan-Cancela, Irene; Nakada, Ayana; Voytyuk, Oleksandr; Tsuchiya, Maiko; Fukui, Rei; Yamamoto, Kouhei; Martin-Rubio, Paula; Sancho, Patricia; Strell, Carina; Micke, Patrick; Wechsler-Reya, Robert J.; Hashizume, Yoshinobu; Miyazono, Kohei; Caja, Laia; Heldin, Carl-Henrik; Swartling, Fredrik J.; Moustakas, Aristidis
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errSave
THYROID HORMONE-INDUCED DIFFERENTIATION: A PROMISING THERAPEUTIC STRATEGY FOR MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-11-11
err0
PREAI
errYang, Yijun; Valdes-Rives, Silvia; Ronsley, Rebecca; Leary, Sarah; Wechsler-Reya, Robert; Yang, Zeng-jie
errShare
errSave
Targeted delivery of napabucasin with radiotherapy improves outcomes in diffuse midline glioma
errNEURO-ONCOLOGY
IF13.4
err2024-10-12
err0
PREAI
errGallitto, Matthew; Zhang, Xu; De Los Santos, Genesis; Wei, Hong-Jian; Fernandez, Ester Calvo; Duan, Shoufu; Sedor, Geoffrey; Yoh, Nina; Kokossis, Danae; Angel, J. Carlos; Wang, Yi-Fang; White, Erin; Kinslow, Connor J.; Berg, Xander; Tomassoni, Lorenzo; Zandkarimi, Fereshteh; Chio, Iok In Christine; Canoll, Peter; Bruce, Jeffrey N.; Feldstein, Neil A.; Gartrell, Robyn D.; Cheng, Simon K.; Garvin, James H.; Zacharoulis, Stergios; Wechsler-Reya, Robert J.; Pavisic, Jovana; Califano, Andrea; Zhang, Zhiguo; Wu, Cheng-Chia
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errSave
CONSERVATION AND FAITHFUL REPRESENTATION OF CIRCULAR EXTRACHROMOSOMAL DNA IN ORTHOTOPIC PATIENT-DERIVED MEDULLOBLASTOMA XENOGRAFTS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errKenkre, Rishaan; Chapman, Owen; Luebeck, Jens; Bafna, Vineet; Wechsler-Reya, Robert J.; Mesirov, Jill; Chavez, Lukas
errShare
errSave
PNOC016: INTRATUMORAL PHARMACOKINETICS AND PHARMACODYNAMIC (PK/PD) RESULTS FROM A TARGET VALIDATION STUDY OF A NOVEL PAN-HDAC AND PI3K INHIBITOR, FIMEPINOSTAT, IN CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG), RECURRENT MEDULLOBLASTOMA (MB), AND RECURRENT HIGH-GRADE GLIOMA (HGG)
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errKline, Cassie; Crawford, John R.; Reddy, Alyssa T.; Gerber, Nicolas; Stucklin, Ana Guerreiro; Kilburn, Lindsay; Packer, Roger; Margol, Ashley; Crotty, Erin; Sayour, Elias; Franson, Andrea; Phillips, Joanna; Singh, Shefali; Hamanishi, Erin; Lee, Christopher; Bhatia, Aashim; George, Elizabeth; Rauschecker, Andreas; Molinaro, Annette; Prados, Michael; Nazarian, Javad; Venneti, Sriram; Wechsler-Reya, Robert; Mueller, Sabine
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errSave
EARLY INSIGHTS FROM PNOC027: PERSONALIZED TREATMENT APPROACHES BASED ON REAL-TIME DRUG SCREENING AND GENOMIC TESTING IN PEDIATRIC AND ADOLESCENT PATIENTS WITH RECURRENT MEDULLOBLASTOMA
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errShatara, Margaret; Paul, Megan R.; Long-Boyle, Janel R.; Meyer, Ashley; Raber, Shannon; Yeh-Nayre, Lanipua; Jalkanen, Aimee; Kilburn, Lindsay B.; Packer, Roger J.; Elster, Jennifer D.; Reddy, Alyssa T.; Koschmann, Carl; Kraya, Adam; Resnick, Adam C.; Prados, Michael; Kline, Cassie; Mueller, Sabine; Wechsler-Reya, Robert J.; Rubin, Joshua B.
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errSave
MULTI-OMICS AND FUNCTIONAL PRECISION MEDICINE FOR NEWLY DIAGNOSED AND RECURRENT PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errCrawford, John R.; Lo, Yan Yuen; Pagadala, Meghana S.; Chapman, Owen S.; Sridhar, Sunita; Juarez, Edwin F.; Tzaridis, Theophilos; Chau, Lianne Q.; Wang, Jun; Eisemann, Tanja; Masihi, Meher Beigi; Chambers, Kendall R.; Dixit, Deobrat; Koubourli, Daphne; Larson, Jon D.; Guidugli, Lucia; Hammer, Monia; Wong, Terence; Abdullaev, Zied; Quezado, Martha; Martins, Timothy J.; Reich, Michael; Sears, Timothy; Hobbs, Charlotte; Kingsmore, Stephen F.; Levy, Michael L.; Gonda, David; Malicki, Denise M.; Snuderl, Matija; Becker, Pamela S.; Tamayo, Pablo; Elster, Jennifer D.; Aldape, Kenneth; Carter, Hannah; Paul, Megan R.; Mesirov, Jill P.; Chavez, Lukas; Wechsler-Reya, Robert J.
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errSave
DRUG SCREENING IN PATIENT-DERIVED MODELS OF POSTERIOR FOSSA A EPENDYMOMA REVEALS NOVEL PHARMACOLOGICAL VULNERABILITIES
errNEURO-ONCOLOGY
IF13.4
err2024-06-18
err0
errOAAI
errLarson, Jon D.; Finlay, Darren; Murad, Rabi; Lo, Yan Yuen; Zhao, Ming; Manuvel, Antony Michealraj Kulandai; Kumar, Sachin A.; Pass, Ian; Handley, Charles; Wechsler-Reya, Robert J.; Taylor, Michael D.; Vuori, Kristiina; Chavez, Lukas; Jackson, Michael
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errSave
The Virtual Child
errCANCER DISCOVERY
IF33.3
err2024-04-04
err1
errOAAI
errGilbertson, Richard J.; Behjati, Sam; Boettcher, Anna-Lisa; Bronner, Marianne E.; Burridge, Matthew; Clausing, Henrick; Clifford, Harry; Danaher, Tracey; Donovan, Laura K.; Drost, Jarno; Eggermont, Alexander M. M.; Emerson, Chris; Flores, Mona G.; Hamerlik, Petra; Jabado, Nada; Jones, Andrew; Kaessmann, Henrick; Kleinman, Claudia L.; Kool, Marcel; Kutscher, Lena M.; Lindberg, Gavin; Linnane, Emily; Marioni, John C.; Maris, John M.; Monje, Michelle; Macaskill, Alexandra; Niederer, Steven; Northcott, Paul A.; Peeters, Elizabeth; Plieger-van Solkema, Willemijn; Preussner, Liane; Rios, Anne C.; Rippe, Karsten; Sandford, Peter; Sgourakis, Nikolaos G.; Shlien, Adam; Smith, Pete; Straathof, Karin; Sullivan, Patrick J.; Suva, Mario L.; Taylor, Michael D.; Thompson, Emma; Vento-Tormo, Roser; Wainwright, Brandon J.; Wechsler-Reya, Robert J.; Westermann, Frank; Winslade, Shannon; Al-Lazikani, Bissan; Pfister, Stefan M.
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errSave
ONC206 inhibits tumour growth and is a potential novel therapeutic strategy for refractory medulloblastoma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errTzaridis, Theophilos; Liu, Jingbo; Prabhu, Varun; Wechsler-Reya, Robert; MacDonald, Tobey
errShare
errSave
Conservation and faithful representation of circular extrachromosomal DNA in orthotopic patient-derived medulloblastoma xenografts
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errKenkre, Rishaan; Chapman, Owen; Luebeck, Jens; Bafna, Vineet; Wechsler-Reya, Robert; Mesirov, Jill; Chavez, Lukas
errShare
errSave
CD155 regulates cell growth and immune evasion in diffuse midline glioma
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errTzaridis, Theophilos; Eisemann, Tanja; Andrade, Augusto Faria; Hope, Jennifer L.; Becher, Oren; Jabado, Nada; Bradley, Linda M.; Adams, Peter; Wechsler-Reya, Robert
errShare
errSave
Just a spoonful of metformin helps the medicine go down
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2024-03-15
err1
errOAAI
errTzaridis, Theophilos; Wechsler-Reya, Robert J.
errShare
errSave

Research Directions

No research directions
Co-authors
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Robert J. Lefkowitz
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Steven J.M. Jones
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Marc G. Caron
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