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Phase II trial of vaccination with autologous, irradiated melanoma cells engineered by adenoviral mediated gene transfer to secrete granulocyte-macrophage colony stimulating factor in patients with stage III and IV melanoma Sussman, Tamara A.; Severgnini, Mariano; Giobbie-Hurder, Anita; Friedlander, Philip; Swanson, Scott J.; Jaklitsch, Michael; Clancy, Thomas; Goguen, Laura A.; Lautz, David; Swanson, Richard; Daley, Heather; Ritz, Jerome; Dranoff, Glenn; Hodi, F. Stephen Share Save
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy Bonazzi, Simone; d'Hennezel, Eva; Beckwith, Rohan E. J.; Xu, Lei; Fazal, Aleem; Magracheva, Anna; Ramesh, Radha; Cernijenko, Artiom; Antonakos, Brandon; Bhang, Hyo-eun C.; Caro, Roxana Garcia; Cobb, Jennifer S.; Ornelas, Elizabeth; Ma, Xiaolei; Wartchow, Charles A.; Clifton, Matthew C.; Forseth, Ry R.; Fortnam, Bethany Hughes; Lu, Hongbo; Csibi, Alfredo; Tullai, Jennifer; Carbonneau, Seth; Thomsen, Noel M.; Larrow, Jay; Chie-Leon, Barbara; Hainzl, Dominik; Gu, Yi; Lu, Darlene; Meyer, Matthew J.; Alexander, Dylan; Kinyamu-Akunda, Jacqueline; Sabatos-Peyton, Catherine A.; Dales, Natalie A.; Zecri, Frederic J.; Jain, Rishi K.; Shulok, Janine; Wang, Y. Karen; Briner, Karin; Porter, Jeffery A.; Tallarico, John A.; Engelman, Jeffrey A.; Dranoff, Glenn; Bradner, James E.; Visser, Michael; Solomon, Jonathan M. Share Save
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Characterization of sabatolimab, a novel immunotherapy with immuno-myeloid activity directed against TIM-3 receptor Schwartz, Stephanie; Patel, Nidhi; Longmire, Tyler; Jayaraman, Pushpa; Jiang, Xiaomo; Lu, Hongbo; Baker, Lisa; Velez, Janelle; Ramesh, Radha; Wavreille, Anne-Sophie; Verneret, Melanie; Fan, Hong; Hu, Tiancen; Xu, Fangmin; Taraszka, John; Pelletier, Marc; Miyashiro, Joy; Rinne, Mikael; Dranoff, Glenn; Sabatos-Peyton, Catherine; Cremasco, Viviana Share Save
The feasibility of using an autologous GM-CSF-secreting breast cancer vaccine to induce immunity in patients with stage II-III and metastatic breast cancers Anderson, Karen S.; Erick, Timothy K.; Chen, Meixuan; Daley, Heather; Campbell, Margaret; Colson, Yolonda; Mihm, Martin; Zakka, Labib R.; Hopper, Marika; Barry, William; Winer, Eric P.; Dranoff, Glenn; Overmoyer, Beth Share Save
GM-CSF secreting leukemia cell vaccination for MDS/AML after allogeneic HSCT: a randomized, double-blinded, phase 2 trial Ho, Vincent T.; Kim, Haesook T.; Brock, Jennifer; Galinsky, Ilene; Daley, Heather; Reynolds, Carol; Weber, Augustine; Pozdnyakova, Olga; Severgnini, Mariano; Nikiforow, Sarah; Cutler, Corey; Koreth, John; Alyea, Edwin P.; Antin, Joseph H.; Gooptu, Mahasweta; Romee, Rizwan; Shapiro, Roman; Chen, Yi-Bin; Rosenblatt, Jacalyn; Avigan, David; Hodi, F. Stephen; Dranoff, Glenn; Wu, Catherine J.; Ritz, Jerome; Soiffer, Robert J. Share Save
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity Carbonneau, Seth; Sharma, Sujata; Peng, Liaomin; Rajan, Vaisakh; Hainzl, Dominik; Henault, Martin; Yang, Chian; Hale, Jacob; Shulok, Janine; Tallarico, John; Porter, Jeff; Brogdon, Jennifer L.; Dranoff, Glenn; Bradner, James E.; Hild, Marc; Guimaraes, Carla P. Share Save
An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity (Dec, 10.1016/j.chembiol.2020.11.012, 2020) Carbonneau, Seth; Sharma, Sujata; Peng, Liaomin; Rajan, Vaisakh; Hainzl, Dominik; Henault, Martin; Yang, Chian; Hale, Jacob; Shulok, Janine; Tallarico, John; Porter, Jeff; Brogdon, Jennifer L.; Dranoff, Glenn; Bradner, James E.; Hild, Marc; Guimaraes, Carla P. Share Save
SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms Wang, Ye; Mohseni, Morvarid; Grauel, Angelo; Diez, Javier Estrada; Guan, Wei; Liang, Simon; Choi, Jiyoung Elizabeth; Pu, Minying; Chen, Dongshu; Laszewski, Tyler; Schwartz, Stephanie; Gu, Jane; Mansur, Leandra; Burks, Tyler; Brodeur, Lauren; Velazquez, Roberto; Kovats, Steve; Pant, Bhavesh; Buruzula, Giri; Deng, Emily; Chen, Julie T.; Sari-Sarraf, Farid; Dornelas, Christina; Varadarajan, Malini; Yu, Haiyan; Liu, Chen; Lim, Joanne; Hao, Huai-Xiang; Jiang, Xiaomo; Malamas, Anthony; LaMarche, Matthew J.; Geyer, Felipe Correa; McLaughlin, Margaret; Costa, Carlotta; Wagner, Joel; Ruddy, David; Jayaraman, Pushpa; Kirkpatrick, Nathaniel D.; Zhang, Pu; Iartchouk, Oleg; Aardalen, Kimberly; Cremasco, Viviana; Dranoff, Glenn; Engelman, Jeffrey A.; Silver, Serena; Wang, Hongyun; Hastings, William D.; Goldoni, Silvia Share Save
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TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblasts Grauel, Angelo L.; Nguyen, Beverly; Ruddy, David; Laszewski, Tyler; Schwartz, Stephanie; Chang, Jonathan; Chen, Julie; Piquet, Michelle; Pelletier, Marc; Yan, Zheng; Kirkpatrick, Nathaniel D.; Wu, Jincheng; deWeck, Antoine; Riester, Markus; Hims, Matt; Geyer, Felipe Correa; Wagner, Joel; MacIsaac, Kenzie; Deeds, James; Diwanji, Rohan; Jayaraman, Pushpa; Yu, Yenyen; Simmons, Quincey; Weng, Shaobu; Raza, Alina; Minie, Brian; Dostalek, Mirek; Chikkegowda, Pavitra; Ruda, Vera; Iartchouk, Oleg; Chen, Naiyan; Thierry, Raphael; Zhou, Joseph; Pruteanu-Malinici, Iulian; Fabre, Claire; Engelman, Jeffrey A.; Dranoff, Glenn; Cremasco, Viviana Share Save
Targeting tumor-promoting inflammation (TPI) via the IL-1βpathway for cancer immunotherapy Jayaraman, Pushpa; Rodrik-Outmezguine, Vanessa; Millholland, John; O'Brien, Neil; Wong, Connie; Diwanji, Rohan; Wang, Muchun; Choi, Elizabeth; Linnartz, Ronald; Rose, Kristine; Pelletier, Marc; Savchenko, Alexander; Luo, Tong; Rezek, Valerie; Kitchen, Scott; Baum, Jason; Sabatos-Peyton, Catherine; Martin, Anne-Marie; Dranoff, Glenn Share Save
Targeting IL-β pathway for cancer immunotherapy Jayaraman, Pushpa; Millholland, John; O'Brien, Neil; Wong, Connie; Diwanji, Rohan; Wang, Muchun; Choi, Elizabeth; Linnartz, Ronald; Rose, Kristine; Rodrik-Outmezguine, Vanessa; Pelletier, Marc; Savchenko, Alexander; Luo, Tong; Rezek, Valerie; Kitchen, Scott; Baum, Jason; Sabatos-Peyton, Catherine; Martin, Anne-Marie; Dranoff, Glenn Share Save
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Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors (vol 24, pg 1459, 2018) Chongsathidkiet, Pakawat; Jackson, Christina; Koyama, Shohei; Loebel, Franziska; Cui, Xiuyu; Farber, Harrison; Woroniecka, Karolina; Elsamadicy, Aladine A.; Dechant, Cosette A.; Kemeny, Hanna R.; Sanchez-Perez, Luis; Cheema, Tooba A.; Souders, Nicholas C.; Herndon, James E.; Coumans, Jean-Valery; Everitt, Jeffrey I.; Nahed, Brian V.; Sampson, John H.; Gunn, Michael D.; Martuza, Robert L.; Dranoff, Glenn; Curry, William T.; Fecci, Peter E. Share Save
Drug Discovery for Kinetoplastid Diseases: Future Directions Rao, Srinivasa P. S.; Barrett, Michael P.; Dranoff, Glenn; Faraday, Christopher J.; Gimpelewicz, Claudio R.; Hailu, Asrat; Jones, Catherine L.; Kelly, John M.; Lazdins-Helds, Jams K.; Maser, Pascal; Mengel, Jose; Mottram, Jeremy C.; Mowbray, Charles E.; Sacks, David L.; Scott, Phillip; Spath, Gerald F.; Tarleton, Rick L.; Spector, Jonathan M.; Diagana, Thierry T. Share Save
Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients Osa, Akio; Uenami, Takeshi; Koyama, Shohei; Fujimoto, Kosuke; Okuzaki, Daisuke; Takimoto, Takayuki; Hirata, Haruhiko; Yano, Yukihiro; Yokota, Soichiro; Kinehara, Yuhei; Naito, Yujiro; Otsuka, Tomoyuki; Kanazu, Masaki; Kuroyama, Muneyoshi; Hamaguchi, Masanari; Koba, Taro; Futami, Yu; Ishijima, Mikako; Suga, Yasuhiko; Akazawa, Yuki; Machiyama, Hirotomo; Iwahori, Kota; Takamatsu, Hyota; Nagatomo, Izumi; Takeda, Yoshito; Kida, Hiroshi; Akbay, Esra A.; Hammerman, Peter S.; Wong, Kwok-Kin; Dranoff, Glenn; Mori, Masahide; Kijima, Takashi; Kumanogoh, Atsushi Share Save
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors Chongsathidkiet, Pakawat; Jackson, Christina; Koyama, Shohei; Loebel, Franziska; Cui, Xiuyu; Farber, S. Harrison; Woroniecka, Karolina; Elsamadicy, Aladine A.; Dechant, Cosette A.; Kemeny, Hanna R.; Sanchez-Perez, Luis; Cheema, Tooba A.; Souders, Nicholas C.; Herndon, James E.; Coumans, Jean-Valery; Everitt, Jeffrey, I; Nahed, Brian, V; Sampson, John H.; Gunn, Michael D.; Martuza, Robert L.; Dranoff, Glenn; Curry, William T.; Fecci, Peter E. Share Save
PD-1/PD-L1 blockade enhances MDM2 inhibitor activity in p53 wild-type cancers Wang, Hui Qin; Liang, Jinsheng; Mulford, Iain; Sharp, Fiona; Gaulis, Swann; Chen, Yan; Trabucco, Gina; Quinn, David; Growney, Joseph D.; Meyer, Matthew J.; Williams, Juliet; Hammerman, Peter; Hofmann, Francesco; Dranoff, Glenn; Engelman, Jeffrey; Mataraza, Jennifer; Halilovic, Ensar Share Save
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