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Lori A. Coburn

Department of Medicine

31H-index
147Paper Count
2.9KCitation Count
Published Papers 36
Publication Date
Regulation of EIF5A and hypusination by p53 determines colorectal cancer cell fitness
err2026-06-15
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errAlain P. Gobert; Caroline V. Hawkins; Mohammad Asim; Daniel P. Barry; Alberto G. Delgado; Regina N. Tyree; Kate S. Carson; Nikhil P.S. Kahlon; Mark V. Ciampa; Kristie L. Rose; Purvi Patel; Ganesh V. Pusapati; Rajat Rohatgi; Wang Yu; Shilin Zhao; Lori A. Coburn; M. Blanca Piazuelo; Keith T. Wilson
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Epithelial hypusination regulates Helicobacter pylori-induced gastric inflammation
err2026-02-02
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errAlain P. Gobert; Kara M. McNamara; Caroline V. Hawkins; Mohammad Asim; Daniel P. Barry; Alberto G. Delgado; Kristie L. Rose; Purvi Patel; Regina N. Tyree; Kate S. Carson; Lori A. Coburn; M. Blanca Piazuelo; Keith T. Wilson
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Aconitate Decarboxylase 1 Downregulates Colitis and Maintains Homeostasis of the Gut Metabolome and Microbiome
err2025-09-01
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errMcNamara, Kara M.; Latour, Yvonne L.; Hawkins, Caroline V.; Williams, Kamery J.; Barry, Daniel P.; Allaman, Margaret M.; Delgado, Alberto G.; Chetyrkin, Sergei V.; Calcutt, M. Wade; Piazuelo, M. Blanca; Washington, M. Kay; Zhao, Shilin; Coburn, Lori A.; Gobert, Alain P.; Wilson, Keith T.
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Protective role of epithelial deoxyhypusine synthase in colorectal carcinogenesis caused by deletion of the adenomatous polyposis coli gene
err2025-08-24
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errAlain P. Gobert; Caroline V. Hawkins; Lydia A. Snyder; Kamery J. Williams; Daniel P. Barry; Margaret M. Allaman; Mohammad Asim; Kara M. McNamara; Shane M. Carey; Alberto G. Delgado; Regina N. Tyree; Kristie L. Rose; Yu Wang; Shilin Zhao; Olivier Boutaud; Irène Zagol-Ikapitte; M. Blanca Piazuelo; M. Kay Washington; Lori A. Coburn; Keith T. Wilson
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Spermine oxidase promotes Helicobacter pylori-mediated gastric carcinogenesis through acrolein production
err2024-11-10
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errMcNamara, Kara M.; Sierra, Johanna C.; Latour, Yvonne L.; Hawkins, Caroline V.; Asim, Mohammad; Williams, Kamery J.; Barry, Daniel P.; Allaman, Margaret M.; Zagol-Ikapitte, Irene; Luis, Paula B.; Schneider, Claus; Delgado, Alberto G.; Piazuelo, M. Blanca; Tyree, Regina N.; Carson, Kate S.; Choksi, Yash A.; Coburn, Lori A.; Gobert, Alain P.; Wilson, Keith T.
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The reverse transsulfuration pathway affects the colonic microbiota and contributes to colitis in mice
err2024-10-19
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errGobert, Alain P.; Latour, Yvonne L.; McNamara, Kara M.; Hawkins, Caroline V.; Williams, Kamery J.; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Delgado, Alberto G.; Milne, Ginger L.; Zhao, Shilin; Piazuelo, M. Blanca; Washington, M. Kay; Coburn, Lori A.; Wilson, Keith T.
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Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease
err2024-08-22
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errLi, Jia; Simmons, Alan J.; Hawkins, Caroline V.; Chiron, Sophie; Ramirez-Solano, Marisol A.; Tasneem, Naila; Kaur, Harsimran; Xu, Yanwen; Revetta, Frank; Vega, Paige N.; Bao, Shunxing; Cui, Can; Tyree, Regina N.; Raber, Larry W.; Conner, Anna N.; Pilat, Jennifer M.; Jacobse, Justin; Mcnamara, Kara M.; Allaman, Margaret M.; Raffa, Gabriella A.; Gobert, Alain P.; Asim, Mohammad; Goettel, Jeremy A.; Choksi, Yash A.; Beaulieu, Dawn B.; Dalal, Robin L.; Horst, Sara N.; Pabla, Baldeep S.; Huo, Yuankai; Landman, Bennett A.; Roland, Joseph T.; Scoville, Elizabeth A.; Schwartz, David A.; Washington, M. Kay; Shyr, Yu; Wilson, Keith T.; Coburn, Lori A.; Lau, Ken S.; Liu, Qi
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Analysis of the effect of hypusination in myeloid cells on colitis and colitis-associated cancer
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IF3.6
err2024-07-01
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errGobert, Alain P.; Finley, Jordan; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Hawkins, Caroline, V; Williams, Kamery J.; Delagado, Alberto G.; Mirmira, Raghavendra G.; Zhao, Shilin; Piazuelo, M. Blanca; Washington, M. Kay; Coburn, Lori A.; Wilson, Keith T.
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Cross-scale multi-instance learning for pathological image diagnosis
err2024-05-01
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errDeng, Ruining; Cui, Can; Remedios, Lucas W.; Bao, Shunxing; Womick, R. Michael; Chiron, Sophie; Li, Jia; Roland, Joseph T.; Lau, Ken S.; Liu, Qi; Wilson, Keith T.; Wang, Yaohong; Coburn, Lori A.; Landman, Bennett A.; Huo, Yuankai
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Hypusination Maintains Intestinal Homeostasis and Prevents Colitis and Carcinogenesis by Enhancing Aldehyde Detoxification
err2023-09-01
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errGobert, Alain P.; Smith, Thaddeus M.; Latour, Yvonne L.; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Williams, Kamery J.; McNamara, Kara M.; Delgado, Alberto G.; Short, Sarah P.; Mirmira, Raghavendra G.; Rose, Kristie L.; Schey, Kevin L.; Zagol-Ikapitte, Irene; Coleman, Jeremy S.; Boutaud, Olivier; Zhao, Shilin; Piazuelo, M. Blanca; Washington, M. Kay; Coburn, Lori A.; Wilson, Keith T.
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Electrophilic reactive aldehydes as a therapeutic target in colorectal cancer prevention and treatment
err2023-04-10
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errGobert, Alain P.; Asim, Mohammad; Smith, Thaddeus M.; Williams, Kamery J.; Barry, Daniel P.; Allaman, Margaret M.; McNamara, Kara M.; Hawkins, Caroline V.; Delgado, Alberto G.; Zhao, Shilin; Piazuelo, M. Blanca; Washington, M. Kay; Coburn, Lori A.; Rathmacher, John A.; Wilson, Keith T.
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Eosinophils Exert Antitumorigenic Effects in the Development of Esophageal Squamous Cell Carcinoma
err2023-01-01
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errJacobse, Justin; Aziz, Zaryab; Sun, Lili; Chaparro, Jasmine; Pilat, Jennifer M.; Kwag, Aaron; Buendia, Matthew; Wimbiscus, Mae; Nasu, Motomi; Saito, Tsuyoshi; Mine, Shinji; Orita, Hajime; Revetta, Frank; Short, Sarah P.; Washington, M. Kay; Hiremath, Girish; Gibson, Michael K.; Coburn, Lori A.; Koyama, Tatsuki; Goettel, Jeremy A.; Williams, Christopher S.; Choksi, Yash A.
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Protective Role of Spermidine in Colitis and Colon Carcinogenesis
err2022-03-01
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errGobert, Alain P.; Latour, Yvonne L.; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Finley, Jordan L.; Smith, Thaddeus M.; McNamara, Kara M.; Singh, Kshipra; Sierra, Johanna C.; Delgado, Alberto G.; Luis, Paula B.; Schneider, Claus; Washington, M. Kay; Piazuelo, M. Blanca; Zhao, Shilin; Coburn, Lori A.; Wilson, Keith T.
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CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis
err2021-10-08
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errPolosukhina, Dina; Singh, Kshipra; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Hardbower, Dana M.; Piazuelo, M. Blanca; Washington, M. Kay; Gobert, Alain P.; Wilson, Keith T.; Coburn, Lori A.
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Dicarbonyl Electrophiles Mediate Inflammation-Induced Gastrointestinal Carcinogenesis
err2021-03-01
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errGobert, Alain P.; Boutaud, Olivier; Asim, Mohammad; Zagol-Ikapitte, Irene A.; Delgado, Alberto G.; Latour, Yvonne L.; Finley, Jordan L.; Singh, Kshipra; Verriere, Thomas G.; Allaman, Margaret M.; Barry, Daniel P.; McNamara, Kara M.; Sierra, Johanna C.; Amarnath, Venkataraman; Tantawy, Mohammed N.; Bimczok, Diane; Piazuelo, M. Blanca; Washington, M. Kay; Zhao, Shilin; Coburn, Lori A.; Wilson, Keith T.
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An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease
err2020-08-04
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errBrubaker, Douglas K.; Kumar, Manu P.; Chiswick, Evan L.; Gregg, Cecil; Starchenko, Alina; Vega, Paige N.; Southard-Smith, Austin N.; Simmons, Alan J.; Scoville, Elizabeth A.; Coburn, Lori A.; Wilson, Keith T.; Lau, Ken S.; Lauffenburger, Douglas A.
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Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma (vol 38, pg 5091, 2019)
err2019-05-08
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errShort, Sarah P.; Barrett, Caitlyn W.; Stengel, Kristy R.; Revetta, Frank L.; Choksi, Yash A.; Coburn, Lori A.; Lintel, Mary K.; McDonough, Elizabeth M.; Washington, M. Kay; Wilson, Keith T.; Prokhortchouk, Egor; Chen, Xi; Hiebert, Scott W.; Reynolds, Albert B.; Williams, Christopher S.
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Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma
err2019-03-11
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errShort, Sarah P.; Barrett, Caitlyn W.; Stengel, Kristy R.; Revetta, Frank L.; Choksi, Yash A.; Coburn, Lori A.; Lintel, Mary K.; McDonough, Elizabeth M.; Washington, M. Kay; Wilson, Keith T.; Prokhortchouk, Egor; Chen, Xi; Hiebert, Scott W.; Reynolds, Albert B.; Williams, Christopher S.
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Serum Polyunsaturated Fatty Acids Correlate with Serum Cytokines and Clinical Disease Activity in Crohn's Disease
err2019-02-27
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errScoville, Elizabeth A.; Allaman, Margaret M.; Adams, Dawn W.; Motley, Amy K.; Peyton, Shannon C.; Ferguson, Sarah L.; Horst, Sara N.; Williams, Christopher S.; Beaulieu, Dawn B.; Schwartz, David A.; Wilson, Keith T.; Coburn, Lori A.
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Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis
err2018-09-10
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errCoburn, Lori A.; Singh, Kshipra; Asim, Mohammad; Barry, Daniel P.; Allaman, Margaret M.; Al-Greene, Nicole T.; Hardbower, Dana M.; Polosukhina, Dina; Williams, Christopher S.; Delgado, Alberto G.; Piazuelo, M. Blanca; Washington, M. Kay; Gobert, Alain P.; Wilson, Keith T.
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