Not logged in Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema Brouillard, Pascal; Murtomaki, Aino; Leppanen, Veli-Matti; Hyytiainen, Marko; Mestre, Sandrine; Potier, Lucas; Boon, Laurence M.; Revencu, Nicole; Greene, Arin; Anisimov, Andrey; Salo, Miia H.; Hinttala, Reetta; Eklund, Lauri; Quere, Isabelle; Alitalo, Kari; Vikkula, Miikka Share Save
Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection Kerkela, Risto; Karsikas, Sara; Szabo, Zoltan; Serpi, Raisa; Magga, Johanna; Gao, Erhe; Alitalo, Kari; Anisimov, Andrey; Sormunen, Raija; Pietila, Ilkka; Vainio, Laura; Koch, Walter J.; Kivirikko, Kari I.; Myllyharju, Johanna; Koivunen, Peppi Share Save
The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium Anisimov, Andrey; Fang, Shentong; Hemanthakumar, Karthik Amudhala; Ord, Tiit; van Avondt, Kristof; Chevre, Raphael; Toropainen, Anu; Singha, Prosanta; Gilani, Huda; Nguyen, Su D.; Karaman, Sinem; Korhonen, Emilia A.; Adams, Ralf H.; Augustin, Hellmut G.; Oorni, Katariina; Soehnlein, Oliver; Kaikkonen, Minna U.; Alitalo, Kari Share Save
Lymphangiogenesis requires Ang2/Tie/PI3K signaling for VEGFR3 cell-surface expression Korhonen, Emilia A.; Murtomaki, Aino; Jha, Sawan Kumar; Anisimov, Andrey; Pink, Anne; Zhang, Yan; Stritt, Simon; Liaqat, Inam; Stanczuk, Lukas; Alderfer, Laura; Sun, Zhiliang; Kapiainen, Emmi; Singh, Abhishek; Sultan, Ibrahim; Lantta, Anni; Leppanen, Veli-Matti; Eklund, Lauri; He, Yulong; Augustin, Hellmut G.; Vaahtomeri, Kari; Saharinen, Pipsa; Makinen, Taija; Alitalo, Kari Share Save
The SARS-CoV-2 receptor ACE2 is expressed in mouse pericytes but not endothelial cells: Implications for COVID-19 vascular research Muhl, Lars; He, Liqun; Sun, Ying; Mae, Maarja Andaloussi; Pietila, Riikka; Liu, Jianping; Genove, Guillem; Zhang, Lei; Xie, Yuan; Leptidis, Stefanos; Mocci, Giuseppe; Stritt, Simon; Osman, Ahmed; Anisimov, Andrey; Hemanthakumar, Karthik Amudhala; Rasanen, Markus; Hansson, Emil M.; Bjorkegren, Johan; Vanlandewijck, Michael; Blomgren, Klas; Makinen, Taija; Peng, Xiao-Rong; Hu, Yizhou; Ernfors, Patrik; Arnold, Thomas D.; Alitalo, Kari; Lendahl, Urban; Betsholtz, Christer Share Save
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Expression of R-Spondin 1 in ApcMin/+ Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling Lahde, Marianne; Heino, Sarika; Hogstrom, Jenny; Kaijalainen, Seppo; Anisimov, Andrey; Flanagan, Dustin; Kallio, Pauliina; Leppanen, Veli-Matti; Ristimaki, Ari; Ritvos, Olli; Wu, Katherine; Tammela, Tuomas; Hodder, Michael; Sansom, Owen J.; Alitalo, Kari Share Save
Consensus guidelines for the use and interpretation of angiogenesis assays Nowak-Sliwinska, Patrycja; Alitalo, Kari; Allen, Elizabeth; Anisimov, Andrey; Aplin, Alfred C.; Auerbach, Robert; Augustin, Hellmut G.; Bates, David O.; van Beijnum, Judy R.; Bender, R. Hugh F.; Bergers, Gabriele; Bikfalvi, Andreas; Bischoff, Joyce; Boeck, Barbara C.; Brooks, Peter C.; Bussolino, Federico; Cakir, Bertan; Carmeliet, Peter; Castranova, Daniel; Cimpean, Anca M.; Cleaver, Ondine; Coukos, George; Davis, George E.; De Palma, Michele; Dimberg, Anna; Dings, Ruud P. M.; Djonov, Valentin; Dudley, Andrew C.; Dufton, Neil P.; Fendt, Sarah-Maria; Ferrara, Napoleone; Fruttiger, Marcus; Fukumura, Dai; Ghesquiere, Bart; Gong, Yan; Griffin, Robert J.; Harris, Adrian L.; Hughes, Christopher C. W.; Hultgren, Nan W.; Iruela-Arispe, M. Luisa; Irving, Melita; Jain, Rakesh K.; Kalluri, Raghu; Kalucka, Joanna; Kerbel, Robert S.; Kitajewski, Jan; Klaassen, Ingeborg; Kleinmann, Hynda K.; Koolwijk, Pieter; Kuczynski, Elisabeth; Kwak, Brenda R.; Marien, Koen; Melero-Martin, Juan M.; Munn, Lance L.; Nicosia, Roberto F.; Noel, Agnes; Nurro, Jussi; Olsson, Anna-Karin; Petrova, Tatiana V.; Pietras, Kristian; Pili, Roberto; Pollard, Jeffrey W.; Post, Mark J.; Quax, Paul H. A.; Rabinovich, Gabriel A.; Raica, Marius; Randi, Anna M.; Ribatti, Domenico; Ruegg, Curzio; Schlingemann, Reinier O.; Schulte-Merker, Stefan; Smith, Lois E. H.; Song, Jonathan W.; Stacker, Steven A.; Stalin, Jimmy; Stratman, Amber N.; Van de Velde, Maureen; van Hinsbergh, Victor W. M.; Vermeulen, Peter B.; Waltenberger, Johannes; Weinstein, Brant M.; Xin, Hong; Yetkin-Arik, Bahar; Yla-Herttuala, Seppo; Yoder, Mervin C.; Griffioen, Arjan W. Share Save
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Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis Rademakers, Timo; van der Vorst, Emiel P. C.; Daissormont, Isabelle T. M. N.; Otten, Jeroen J. T.; Theodorou, Kosta; Theelen, Thomas L.; Gijbels, Marion; Anisimov, Andrey; Nurmi, Harri; Lindeman, Jan H. N.; Schober, Andreas; Heeneman, Sylvia; Alitalo, Kari; Biessen, Erik A. L. Share Save
Tie1 controls angiopoietin function in vascular remodeling and inflammation Korhonen, Emilia A.; Lampinen, Anita; Giri, Hemant; Anisimov, Andrey; Kim, Minah; Allen, Breanna; Fang, Shentong; D'Amico, Gabriela; Sipila, Tuomas J.; Lohela, Marja; Strandin, Tomas; Vaheri, Antti; Yla-Herttuala, Seppo; Koh, Gou Young; McDonald, Donald M.; Alitalo, Kari; Saharinen, Pipsa Share Save
Proteolytic activation defines distinct lymphangiogenic mechanisms for VEGFC and VEGFD Bui, Hung M.; Enis, David; Robciuc, Marius R.; Nurmi, Harri J.; Cohen, Jennifer; Chen, Mei; Yang, Yiqing; Dhillon, Veerpal; Johnson, Kathy; Zhang, Hong; Kirkpatrick, Robert; Traxler, Elizabeth; Anisimov, Andrey; Alitalo, Kari; Kahn, Mark L. Share Save
Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts Dashkevich, A.; Raissadati, A.; Syrjala, S. O.; Zarkada, G.; Keranen, M. A. I.; Tuuminen, R.; Krebs, R.; Anisimov, A.; Jeltsch, M.; Leppanen, V. -M.; Alitalo, K.; Nykanen, A. I.; Lemstrom, K. B. Share Save
Endothelial Bmx tyrosine kinase activity is essential for myocardial hypertrophy and remodeling Holopainen, Tanja; Rasanen, Markus; Anisimov, Andrey; Tuomainen, Tomi; Zheng, Wei; Tvorogov, Denis; Hulmi, Juha J.; Andersson, Leif C.; Cenni, Bruno; Tavi, Pasi; Mervaala, Eero; Kivela, Riikka; Alitalo, Kari Share Save
CCBE1 Enhances Lymphangiogenesis via A Disintegrin and Metalloprotease With Thrombospondin Motifs-3-Mediated Vascular Endothelial Growth Factor-C Activation Jeltsch, Michael; Jha, Sawan Kumar; Tvorogov, Denis; Anisimov, Andrey; Leppanen, Veli-Matti; Holopainen, Tanja; Kivela, Riikka; Ortega, Sagrario; Karpanen, Terhi; Alitalo, Kari Share Save
Pulmonary Lymphangiectasia Resulting From Vascular Endothelial Growth Factor-C Overexpression During a Critical Period Yao, Li-Chin; Testini, Chiara; Tvorogov, Denis; Anisimov, Andrey; Vargas, Sara O.; Baluk, Peter; Pytowski, Bronislaw; Claesson-Welsh, Lena; Alitalo, Kari; McDonald, Donald M. Share Save
VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart Kivela, Riikka; Bry, Maija; Robciuc, Marius R.; Rasanen, Markus; Taavitsainen, Miia; Silvola, Johanna M. U.; Saraste, Antti; Hulmi, Juha J.; Anisimov, Andrey; Mayranpaa, Mikko I.; Lindeman, Jan H.; Eklund, Lauri; Hellberg, Sanna; Hlushchuk, Ruslan; Zhuang, Zhen W.; Simons, Michael; Djonov, Valentin; Knuuti, Juhani; Mervaala, Eero; Alitalo, Kari Share Save
Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy D'Amico, Gabriela; Korhonen, Emilia A.; Anisimov, Andrey; Zarkada, Georgia; Holopainen, Tanja; Haegerling, Rene; Kiefer, Friedemann; Eklund, Lauri; Sormunen, Raija; Elamaa, Harri; Brekken, Rolf A.; Adams, Ralf H.; Koh, Gou Young; Saharinen, Pipsa; Alitalo, Kari Share Save
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation Leppanen, Veli-Matti; Tvorogov, Denis; Kisko, Kaisa; Prota, Andrea E.; Jeltsch, Michael; Anisimov, Andrey; Markovic-Mueller, Sandra; Stuttfeld, Edward; Goldie, Kenneth N.; Ballmer-Hofer, Kurt; Alitalo, Kari Share Save
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