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William R. Jacobs

Montefiore Medical Center

127H-index
610Paper Count
5.4WCitation Count
Published Papers 204
Publication Date
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A vaccine platform that promotes Fc-dependent effector functions by recruiting helper T cells induced by prior BCG immunization
errJOURNAL OF IMMUNOLOGY
IF3.4
err2025-11-01
err0
PREAI
errNg, Tony W.; Wirchnianski, Ariel; Furuyama, Wakako; Jacobs, William; Chandran, Kartik; Marzi, Andrea; Porcelli, Steven
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errSave
Loss of the PPE71-esxX-esxY-PPE38 locus drives adaptive transcriptional responses and hypervirulence of Mycobacterium tuberculosis lineage 2
errScience Advances
IF12.5
err2025-07-04
err0
PREAI
errBenjamin Koleske; Courtney Schill; Saranathan Rajagopalan; Somnath Shee; Yazmin B. Martinez-Martinez; Manish Gupta; Jessica Shen; William R. Jacobs; William R. Bishai
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errSave
Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates
errJOURNAL OF INFECTIOUS DISEASES
IF4.5
err2024-10-16
err0
PREAI
errRajagopalan, Saranathan; Rourke, Amy K.; Asare, Emmanuel; Kohlerschmidt, Donna J.; Das, Lahari; Ngema, Senamile L.; Mulholland, Claire, V; Vilcheze, Catherine; Mahalingam, Vaishnavi; Moodley, Sashen; Truebody, Barry; Mackenzie, Jared; Steyn, Adrie J. C.; Perumal, Rubeshan; Berney, Michael; Larsen, Michelle H.; O'Donnell, Max R.; Escuyer, Vincent E.; Jacobs, William R.
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errSave
A viral vaccine design harnessing prior BCG immunization confers protection against Ebola virus
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-07-16
err0
errOAAI
errNg, Tony W.; Furuyama, Wakako; Wirchnianski, Ariel S.; Saavedra-avila, Noemi A.; Johndrow, Christopher T.; Chandran, Kartik; Jacobs Jr, William R.; Marzi, Andrea; Porcelli, Steven A.
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Boosting Immunogenicity of a Recombinant Mycobacterium smegmatis Strain via Zinc-Dependent Ribosomal Proteins
errBIOMEDICINES
IF3.9
err2024-07-15
err0
errOAAI
errSingh, Shivani; Kanzin, David; Chavez, Sarah; Saavedra-Avila, Noemi Alejandra; Ng, Tony W.; Lukose, Regy; Mayer, Oren; Kim, John; Chen, Bing; Chen, Mei; Porcelli, Steven A.; Jacobs Jr, William R.; Tiwari, Sangeeta
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errSave
Loss-of-function mutations in ndh do not confer delamanid, ethionamide, isoniazid, or pretomanid resistance in Mycobacterium tuberculosis
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2024-01-10
err2
errOAAI
errPandey, Sushil; Vilcheze, Catherine; Werngren, Jim; Bainomugisa, Arnold; Mansjo, Mikael; Groenheit, Ramona; Miotto, Paolo; Cirillo, Daniela M.; Coulter, Christopher; Baulard, Alain R.; Schon, Thomas; Jacobs Jr, William R.; Djaout, Kamel; Koser, Claudio U.
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errSave
The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2023-10-02
err3
errOAAI
errKoleske, Benjamin N.; Jacobs, William R.; Bishai, William R.
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errSave
Mycobacterium tuberculosis Central Metabolism Is Key Regulator of Macrophage Pyroptosis and Host Immunity
errPATHOGENS
IF3.3
err2023-08-30
err1
errOAAI
errMaxson, Michelle E.; Das, Lahari; Goldberg, Michael F.; Porcelli, Steven A.; Chan, John; Jacobs Jr, William R.
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errSave
MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues
errACS INFECTIOUS DISEASES
IF3.8
err2023-03-15
err3
errOAAI
errFeng, Mu; Namanja-Magliano, Hilda; Rajagopalan, Saranathan; Mishra, Tanmay; Ducati, Rodrigo G.; Hirsch, Brett M.; Kelly, Libusha; Szymczak, Wendy; Fajardo, Jorge Eduardo; Sidoli, Simone; Fiser, Andras; Jacobs, William R.; Schramm, Vern L.
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errSave
Mycobacterium bovis Strain Ravenel Is Attenuated in Cattle
errPATHOGENS
IF3.3
err2022-11-11
err2
errOAAI
errHadi, Syeda A.; Brenner, Evan P.; Palmer, Mitchell V.; Waters, W. Ray; Thacker, Tyler C.; Vilcheze, Catherine; Larsen, Michelle H.; Jacobs, William R.; Sreevatsan, Srinand
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errSave
Capturing Structural Variants of Herpes Simplex Virus Genome in Full Length by Oxford Nanopore Sequencing
errMICROBIOLOGY SPECTRUM
IF3.8
err2022-10-26
err8
errOAAI
errSaranathan, Rajagopalan; Asare, Emmanuel; Leung, Lawrence; de Oliveira, Anna Paula; Kaugars, Katherine E.; Mulholland, Claire, V; Lukose, Regy; Berney, Michael; Jacobs, William R., Jr.
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errSave
A world without tuberculosis: moving from imagination to reality
errJOURNAL OF CLINICAL INVESTIGATION
IF13.6
err2022-09-15
err0
errOAAI
errJacobs Jr, William R.
errShare
errSave
Commonalities of Mycobacterium tuberculosis Transcriptomes in Response to Defined Persisting Macrophage Stresses
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-07-01
err12
errOAAI
errVilcheze, Catherine; Yan, Bo; Casey, Rosalyn; Hingley-Wilson, Suzie; Ettwiller, Laurence; Jacobs, William R., Jr.
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errSave
Multiple genetic paths including massive gene amplification allow Mycobacterium tuberculosis to overcome loss of ESX-3 secretion system substrates
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-02-22
err8
errOAAI
errWang, Lin; Asare, Emmanuel; Shetty, Amol C.; Sanchez-Tumbaco, Freddy; Edwards, Megan R.; Saranathan, Rajagopalan; Weinrick, Brian; Xu, Jiayong; Chen, Bing; Benard, Angele; Dougan, Gordon; Leung, Daisy W.; Amarasinghe, Gaya K.; Chan, John; Basler, Christopher F.; Jacobs, William R., Jr.; Tufariello, JoAnn M.
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errSave
A recombinant herpes virus expressing influenza hemagglutinin confers protection and induces antibody-dependent cellular cytotoxicity
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-08-20
err11
errOAAI
errKaugars, Katherine; Dardick, Joseph; de Oliveira, Anna Paula; Weiss, Kayla A.; Lukose, Regy; Kim, John; Leung, Lawrence; Rajagopalan, Saranathan; Wolin, Sydney; Akabas, Leor; Knipe, David M.; Bajic, Goran; Jacobs Jr, William R.
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errSave
The Promises and Limitations of N-Acetylcysteine as a Potentiator of First-Line and Second-Line Tuberculosis Drugs
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2021-04-19
err12
errOAAI
errVilcheze, Catherine; Jacobs, William R., Jr.
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errSave
Sterilization by Adaptive Immunity of a Conditionally Persistent Mutant of Mycobacterium tuberculosis
errMBIO
IF4.7
err2021-02-23
err1
errOAAI
errVilcheze, Catherine; Porcelli, Steven A.; Chan, John; Jacobs, William R., Jr.
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errSave
Drivers and sites of diversity in the DNA adenine methylomes of 93 Mycobacterium tuberculosis complex clinical isolates
errELIFE
IF0
err2020-10-27
err25
errOAAI
errModlin, Samuel J.; Conkle-Gutierrez, Derek; Kim, Calvin; Mitchell, Scott N.; Morrissey, Christopher; Weinrick, Brian C.; Jacobs, William R.; Ramirez-Busby, Sarah M.; Hoffner, Sven E.; Valafar, Faramarz
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Characterization of Large Deletion Mutants of Mycobacterium tuberculosis Selected for Isoniazid Resistance
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2020-08-20
err3
errOAAI
errVilcheze, Catherine; Saranathan, Rajagopalan; Weinrick, Brian; Jacobs, William R., Jr.
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errSave
HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses
errSCIENCE IMMUNOLOGY
IF16.3
err2020-08-14
err17
errOAAI
errAschner, Clare Burn; Loh, Lip Nam; Galen, Benjamin; Delwel, Isabel; Jangra, Rohit K.; Garforth, Scott J.; Chandran, Kartik; Almo, Steven; Jacobs, William R., Jr.; Ware, Carl F.; Herold, Betsy C.
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Research Directions

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Co-authors
Cooperation Journals
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Julian Parkhill
H-index: 177 · Papers: 1.1K
P
Peter G. Schultz
H-index: 159 · Papers: 880
B
Barton F. Haynes
H-index: 144 · Papers: 834
G
Gordon Dougan
H-index: 144 · Papers: 952
A
Arturo Casadevall
H-index: 144 · Papers: 1.5K
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