Not logged in Staphylococcal toxin PVL ruptures model membranes under acidic conditions through interactions with cardiolipin and phosphatidic acid Chow, Seong H.; Jeon, Yusun; Deo, Pankaj; Yeung, Amy T. Y.; Hale, Christine; Sridhar, Sushmita; Abraham, Gilu; Nickson, Joshua; Olivier, Francios A. B.; Jiang, Jhih-Hang; Ding, Yue; Han, Mei-Ling; Le Brun, Anton P.; Anderson, Dovile; Creek, Darren; Tong, Janette; Gabriel, Kip; Li, Jian; Traven, Ana; Dougan, Gordon; Shen, Hsin-Hui; Naderer, Thomas Share Save
Rapid and relaying deleterious effects of a gastrointestinal pathogen, Citrobacter rodentium, on bone, an extra-intestinal organ Sharan, Kunal; Brandt, Cordelia; Yusuf, Mohd Aslam; Singh, Parminder; Halder, Namrita; Edwards, Madeline E.; Mangu, S. V. V. S. Ravi; Das, Abhilipsa; Mishra, Amrita; Kumar, Shashi S.; Sharma, Amita; Gupta, Alka; Liu, Xiaowei S.; Guo, Edward X.; Monani, Umrao R.; Ponnalagu, Devasena; Ivanov, Ivaylo I.; Lal, Girdhari; Clare, Simon; Dougan, Gordon; Yadav, Vijay K. Share Save
Exploiting human immune repertoire transgenic mice for protective monoclonal antibodies against antimicrobial resistant Acinetobacter baumannii Baker, Stephen; Krishna, Aishwarya; Higham, Sophie; Naydenova, Plamena; O'Leary, Siobhan; Scott, Josefin Bartholdson; Harcourt, Katherine; Forrest, Sally; Goulding, David; Nguyen, To Nguyen Thi; Toan, Nguyen Duc; Alekseeva, Elizaveta; Zhou, Qingqing; Andreozzi, Ilaria; Sobotic, Barbara; Craig, Hannah; Wong, Vivian; Forrest-Owen, Nichola; Sanchez, Dana Moreno; Pearce, Claire; Roberts, Leah; Watson, Simon; Clare, Simon; Torok, Mili Estee; Dougan, Gordon; Kellam, Paul; Tregoning, John S.; Reece, Stephen T. Share Save
Characterization of mAbs against Klebsiella pneumoniae type 3 fimbriae isolated in a target-independent phage display campaign Berry, Sophia K.; Rust, Steven; Irving, Lorraine; Scott, Josefin Bartholdson; Weinert, Lucy A.; Dougan, Gordon; Christie, Graham; Warrener, Paul; Minter, Ralph; Grant, Andrew J. Share Save
Combining machine learning with high-content imaging to infer ciprofloxacin susceptibility in isolates of Salmonella Typhimurium Tran, Tuan-Anh; Sridhar, Sushmita; Reece, Stephen T.; Lunguya, Octavie; Jacobs, Jan; Van Puyvelde, Sandra; Marks, Florian; Dougan, Gordon; Thomson, Nicholas R.; Nguyen, Binh T.; Bao, Pham The; Baker, Stephen Share Save
Inter-species gene flow drives ongoing evolution of Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis Xie, Ouli; Morris, Jacqueline M.; Hayes, Andrew J.; Towers, Rebecca J.; Jespersen, Magnus G.; Lees, John A.; Ben Zakour, Nouri L.; Berking, Olga; Baines, Sarah L.; Carter, Glen P.; Tonkin-Hill, Gerry; Schrieber, Layla; McIntyre, Liam; Lacey, Jake A.; James, Taylah B.; Sriprakash, Kadaba S.; Beatson, Scott A.; Hasegawa, Tadao; Giffard, Phil; Steer, Andrew C.; Batzloff, Michael R.; Beall, Bernard W.; Pinho, Marcos D.; Ramirez, Mario; Bessen, Debra E.; Dougan, Gordon; Bentley, Stephen D.; Walker, Mark J.; Currie, Bart J.; Tong, Steven Y. C.; McMillan, David J.; Davies, Mark R. Share Save
Genomic analysis of clinical Aeromonas isolates reveals genetic diversity but little evidence of genetic determinants for diarrhoeal disease Klemm, Elizabeth J.; Nisar, Muhammad Imran; Bawn, Matt; Nasrin, Dilruba; Qamar, Farah Naz; Page, Andrew; Qadri, Farheen; Shakoor, Sadia; Zaidi, Anita K. M.; Levine, Myron M.; Dougan, Gordon; Kingsley, Robert A. Share Save
A metagenomic prospective cohort study on gut microbiome composition and clinical infection in small bowel transplantation Madhav, Archana; Bousfield, Rachel; Pereira-Dias, Joana; Cormie, Claire; Forrest, Sally; Keane, Jacqueline; Kermack, Leanne; Higginson, Ellen; Dougan, Gordon; Spiers, Harry; Massey, Dunecan; Sharkey, Lisa; Rutter, Charlotte; Woodward, Jeremy; Russell, Neil; Amin, Irum; Butler, Andrew; Atkinson, Kayleigh; Dymond, Tom; Scott, Josefin Bartholdson; Baker, Stephen; Gkrania-Klotsas, Effrossyni Share Save
Vaccination to Reduce Antimicrobial Resistance Burden-Data Gaps and Future Research Tadesse, Birkneh Tilahun; Keddy, Karen H.; Rickett, Natasha Y.; Zhusupbekova, Aidai; Poudyal, Nimesh; Lawley, Trevor; Osman, Majdi; Dougan, Gordon; Kim, Jerome H.; Lee, Jung-Seok; Jeon, Hyon Jin; Marks, Florian Share Save
Detecting Residual Chronic Salmonella Typhi Carriers on the Road to Typhoid Elimination in Santiago, Chile, 2017-2019 Lagos, Rosanna M.; Sikorski, Michael J.; Hormazabal, Juan Carlos; Fernandez, Alda; Duarte, Sergio; Pasetti, Marcela F.; Rasko, David A.; Higginson, Ellen; Nkeze, Joseph; Kasumba, Irene N.; Dougan, Gordon; Maes, Mailis; Lees, Andrew; Tennant, Sharon M.; Levine, Myron M. Share Save
The clinical, genomic, and microbiological profile of invasive multi-drug resistant Escherichia coli in a major teaching hospital in the United Kingdom Hamilton, William L.; Coscione, Suny; Maes, Mailis; Warne, Ben; Pike, Lindsay J.; Khokhar, Fahad A.; Blane, Beth; Brown, Nicholas M.; Gouliouris, Theodore; Dougan, Gordon; Torok, M. Estee; Baker, Stephen Share Save
A genomic appraisal of invasive Salmonella Typhimurium and associated antibiotic resistance in sub-Saharan Africa Van Puyvelde, Sandra; de Block, Tessa; Sridhar, Sushmita; Bawn, Matt; Kingsley, Robert A.; Ingelbeen, Brecht; Beale, Mathew A.; Barbe, Barbara; Jeon, Hyon Jin; Mbuyi-Kalonji, Lisette; Phoba, Marie-France; Falay, Dadi; Martiny, Delphine; Vandenberg, Olivier; Affolabi, Dissou; Rutanga, Jean Pierre; Ceyssens, Pieter-Jan; Mattheus, Wesley; Cuypers, Wim L.; van der Sande, Marianne A. B.; Park, Se Eun; Kariuki, Simon; Otieno, Kephas; Lusingu, John P. A.; Mbwana, Joyce R.; Adjei, Samuel; Sarfo, Anima; Agyei, Seth O.; Asante, Kwaku P.; Otieno, Walter; Otieno, Lucas; Tahita, Marc C.; Lompo, Palpouguini; Hoffman, Irving F.; Mvalo, Tisungane; Msefula, Chisomo; Hassan-Hanga, Fatimah; Obaro, Stephen; Mackenzie, Grant; Deborggraeve, Stijn; Feasey, Nicholas; Marks, Florian; Maclennan, Calman A.; Thomson, Nicholas R.; Jacobs, Jan; Dougan, Gordon; Kariuki, Samuel; Lunguya, Octavie Share Save
Salmonella Typhi whole genome sequencing in Rwanda shows a diverse historical population with recent introduction of haplotype H58 Rutanga, Jean Pierre; de Block, Tessa; Cuypers, Wim L.; Cafmeyer, Josephine; Peeters, Marjan; Umumararungu, Esperance; Ngabonziza, Jean Claude S.; Rucogoza, Aniceth; Vandenberg, Olivier; Martiny, Delphine; Dusabe, Angelique; Nkubana, Theoneste; Dougan, Gordon; Muvunyi, Claude Mambo; Mwikarago, Ivan Emil; Jacobs, Jan; Deborggraeve, Stijn; Van Puyvelde, Sandra Share Save
A global genomic analysis of Salmonella Concord reveals lineages with high antimicrobial resistance in Ethiopia Cuypers, Wim L.; Meysman, Pieter; Weill, Francois-Xavier; Hendriksen, Rene S.; Beyene, Getenet; Wain, John; Nair, Satheesh; Chattaway, Marie A.; Perez-Sepulveda, Blanca M.; Ceyssens, Pieter-Jan; de Block, Tessa; Lee, Winnie W. Y.; Pardos de la Gandara, Maria; Kornschober, Christian; Moran-Gilad, Jacob; Veldman, Kees T.; Cormican, Martin; Torpdahl, Mia; Fields, Patricia I.; Cerny, Tomas; Hardy, Liselotte; Tack, Bieke; Mellor, Kate C.; Thomson, Nicholas; Dougan, Gordon; Deborggraeve, Stijn; Jacobs, Jan; Laukens, Kris; Van Puyvelde, Sandra Share Save
Epitopes in the capsular polysaccharide and the porin OmpK36 receptors are required for bacteriophage infection of Klebsiella pneumoniae Dunstan, Rhys A.; Bamert, Rebecca S.; Tan, Kher Shing; Imbulgoda, Uvini; Barlow, Christopher K.; Taiaroa, George; Pickard, Derek J.; Schittenhelm, Ralf B.; Dougan, Gordon; Short, Francesca L.; Lithgow, Trevor Share Save
Genomic analysis unveils genome degradation events and gene flux in the emergence and persistence of S. Paratyphi A lineages Jacob, Jobin John; Pragasam, Agila K.; Vasudevan, Karthick; Velmurugan, Aravind; Priya Teekaraman, Monisha; Priya Thirumoorthy, Tharani; Ray, Pallab; Gupta, Madhu; Kapil, Arti; Bai, Sulochana Putil; Nagaraj, Savitha; Saigal, Karnika; Chandola, Temsunaro Rongsen; Thomas, Maria; Bavdekar, Ashish; Ebenezer, Sheena Evelyn P.; Shastri, Jayanthi; De, Anuradha R.; Dutta, Shantha; Alexander, Anna; Koshy, Roshine Mary; Jinka, Dasaratha; Singh, Ashita; Srivastava, Sunil Kumar; Anandan, Shalini; Dougan, Gordon; John, Jacob M.; Kang, Gagandeep M.; Veeraraghavan, Balaji; Mutreja, Ankur Share Save
FBXO11 governs macrophage cell death and inflammation in response to bacterial toxins Jeon, Yusun; Chow, Seong H.; Stuart, Isabella; Weir, Ashley; Yeung, Amy T. Y.; Hale, Christine; Sridhar, Sushmita; Dougan, Gordon; Vince, James E.; Naderer, Thomas Share Save
Obesity Is Associated with Attenuated Tissue Immunity in COVID-19 Guo, Shuang A.; Bowyer, Georgina S.; Ferdinand, John R.; Maes, Mailis; Tuong, Zewen K.; Gillman, Eleanor; Liao, Mingfeng; Lindeboom, Rik G. H.; Yoshida, Masahiro; Worlock, Kaylee; Gopee, Hudaa; Stephenson, Emily; Gao, Catherine A.; Lyons, Paul A.; Smith, Kenneth G. C.; Haniffa, Muzlifah; Meyer, Kerstin B.; Nikolic, Marko Z.; Zhang, Zheng; Wunderink, Richard G.; Misharin, Alexander, V; Dougan, Gordon; Navapurkar, Vilas; Teichmann, Sarah A.; Morris, Andrew Conway; Clatworthy, Menna R. Share Save
Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity Hodgson, Rose; Crockford, Tanya L.; Bhandari, Aneesha; Kepple, Jessica D.; Back, Jennifer; Cawthorne, Eleanor; Abeler-Dorner, Lucie; Laing, Adam G.; Clare, Simon; Speak, Anneliese; Adams, David J.; Dougan, Gordon; Hayday, Adrian C.; Deobagkar-Lele, Mukta; Cornall, Richard J.; Bull, Katherine R. Share Save
Multiplex MinION sequencing suggests enteric adenovirus F41 genetic diversity comparable to pre- COVID-19 era Maes, Mailis; Khokhar, Fahad; Wilkinson, Sam A. J.; Smith, Andrew D.; Kovalenko, Ganna; Dougan, Gordon; Quick, Joshua; Loman, Nicholas J.; Baker, Stephen; Curran, Martin D.; Skittrall, Jordan P.; Houldcroft, Charlotte J. Share Save
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