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SaveGPR109A activation limits cell growth by inducing p53 and its targets in human colon cancer cells
Thangaraju, Muthusamy; Thangaraju, Nanditi N.; Gilstrap, Lauren; Chimenti, Madison; Patel, Tulshi; Sivaprakasam, Sathish; Patel, Nikhil; Manicassamy, Santhakumar; Prasad, Puttur D.; Ganapathy, Vadivel
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SaveMolecular Mechanism of SLC5A8 Inactivation in Breast Cancer
Elangovan, Selvakumar; Pathania, Rajneesh; Ramachandran, Sabarish; Ananth, Sudha; Padia, Ravi N.; Srinivas, Sonne R.; Babu, Ellappan; Hawthorn, Lesleyann; Schoenlein, Patricia V.; Boettger, Thomas; Smith, Sylvia B.; Prasad, Puttur D.; Ganapathy, Vadivel; Thangaraju, Muthusamy
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SaveGenetic Deletion of LRP5 and LRP6 in Macrophages Exacerbates Colitis-Associated Systemic Inflammation and Kidney Injury in Response to Intestinal Commensal Microbiota
Manoharan, Indumathi; Swafford, Daniel; Shanmugam, Arulkumaran; Patel, Nikhil; Prasad, Puttur D.; Mohamed, Riyaz; Wei, Qingqing; Dong, Zheng; Thangaraju, Muthusamy; Manicassamy, Santhakumar
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SaveRAD51AP1 Loss Attenuates Colorectal Cancer Stem Cell Renewal and Sensitizes to Chemotherapy
Bridges, Allison E.; Ramachandran, Sabarish; Tamizhmani, Kavin; Parwal, Utkarsh; Lester, Adrienne; Rajpurohit, Pragya; Morera, Daley S.; Hasanali, Sarrah L.; Arjunan, Pachiappan; Jedeja, Ravirajsinh N.; Patel, Nikhil; Martin, Pamela M.; Korkaya, Hasan; Singh, Nagendra; Manicassamy, Santhakumar; Prasad, Puttur D.; Lokeshwar, Vinata B.; Lokeshwar, Bal L.; Ganapathy, Vadivel; Thangaraju, Muthusamy
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SaveThe Wnt-β-Catenin-IL-10 Signaling Axis in Intestinal APCs Protects Mice from Colitis-Associated Colon Cancer in Response to Gut Microbiota
Swafford, Daniel; Shanmugam, Arulkumaran; Ranganathan, Punithavathi; Manoharan, Indumathi; Hussein, Mohamed S.; Patel, Nikhil; Sifuentes, Humberto; Koni, Pandelakis A.; Prasad, Puttur D.; Thangaraju, Muthusamy; Manicassamy, Santhakumar
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SaveRAD51AP1 Deficiency Reduces Tumor Growth by Targeting Stem Cell Self-Renewal
Bridges, Allison E.; Ramachandran, Sabarish; Pathania, Rajneesh; Parwal, Utkarsh; Lester, Adrienne; Rajpurohit, Pragya; Morera, Daley S.; Patel, Nikhil; Singh, Nagendra; Korkaya, Hasan; Manicassamy, Santhakumar; Prasad, Puttur D.; Lokeshwar, Vinata B.; Lokeshwar, Bal L.; Ganapathy, Vadivel; Thangaraju, Muthusamy
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SaveMetabolic Reprogramming by MYCN Confers Dependence on the Serine-Glycine-One-Carbon Biosynthetic Pathway
Xia, Yingfeng; Ye, Bingwei; Ding, Jane; Yu, Yajie; Alptekin, Ahmet; Thangaraju, Muthusamy; Prasad, Puttur D.; Ding, Zhi-Chun; Park, Eun Jeong; Choi, Jeong-Hyeon; Gao, Bei; Fiehn, Oliver; Yan, Chunhong; Dong, Zheng; Zha, Yunhong; Ding, Han-Fei
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SaveGPR81, a Cell-Surface Receptor for Lactate, Regulates Intestinal Homeostasis and Protects Mice from Experimental Colitis
Ranganathan, Punithavathi; Shanmugam, Arulkumaran; Swafford, Daniel; Suryawanshi, Amol; Bhattacharjee, Pushpak; Hussein, Mohamed S.; Koni, Pandelakis A.; Prasad, Puttur D.; Kurago, Zoya B.; Thangaraju, Muthusamy; Ganapathy, Vadivel; Manicassamy, Santhakumar
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SaveAmino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
Coothankandaswamy, V.; Cao, S.; Xu, Y.; Prasad, P. D.; Singh, P. K.; Reynolds, C. P.; Yang, S.; Ogura, J.; Ganapathy, V.; Bhutia, Y. D.
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SaveCombined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Pathania, Rajneesh; Ramachandran, Sabarish; Mariappan, Gurusamy; Thakur, Priyanka; Shi, Huidong; Choi, Jeong-Hyeon; Manicassamy, Santhakumar; Kolhe, Ravindra; Prasad, Puttur D.; Sharma, Suash; Lokeshwar, Bal L.; Ganapathy, Vadivel; Thangaraju, Muthusamy
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