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PDAC tumors from patients treated with combination MEK and autophagy inhibition reveal a treatment sensitive epithelial subtype that is enriched in murine models Labadie, Brian W.; Obradovic, Aleksandar Z.; Ana, Sarah Sta; May, Michael; Sender, Naomi; Ross, Isabelle V.; Rodriguez-Mendez, Monica; Wasko, Urszula; Tomassoni, Lorenzo; Li, Li; Vij, Manan; Abuzaid, Sinan; Wulfkuhle, Julia; Wong, Winston; Pellicciotta, Ilenia; Izar, Benjamin; Petricoin, Emanuel F.; Tan, Aik Choon; Olive, Kenneth P.; Raufi, Alex G.; Manji, Gulam A. Share Save
Androgen Deprivation Therapy Drives a Distinct Immune Phenotype in Localized Prostate Cancer Dallos, Matthew C.; Obradovic, Aleksandar Z.; Mccann, Patrick; Chowdhury, Nivedita; Pratapa, Aditya; Aggen, David H.; Gaffney, Christopher; Autio, Karen A.; Virk, Renu K.; De Marzo, Angelo M.; Antonarakis, Emmanuel S.; Scher, Howard I.; Drake, Charles G.; Rathkopf, Dana E. Share Save
Single- cell analysis of treatment- resistant prostate cancer: Implications of cell state changes for cell surface antigen- targeted therapies Zaidi, Samir; Park, Jooyoung; Chan, Joseph M.; Roudier, Martine P.; Zhao, Jimmy L.; Gopalan, Anuradha; Wadosky, Kristine M.; Patel, Radhika A.; Sayar, Erolcan; Karthaus, Wouter R.; Kates, D. Henry; Chaudhary, Ojasvi; Xu, Tianhao; Masilionis, Ignas; Mazutis, Linas; Chaligne, Ronan; Obradovic, Aleksandar; Linkov, Irina; Barlas, Afsar; Jungbluth, Achim A.; Rekhtman, Natasha; Silber, Joachim; Manova-Todorova, Katia; Watson, Philip A.; True, Lawrence D.; Morrissey, Colm; Scher, Howard I.; Rathkopf, Dana E.; Morris, Michael J.; Goodrich, David W.; Choi, Jungmin; Nelson, Peter S.; Haffner, Michael C.; Sawyers, Charles L. Share Save
Efficacy and immunological outcomes of non-fucosylated anti-CTLA-4 (BMS-986218) + degarelix acetate vs. degarelix acetate alone in men with high-risk localized prostate cancer (Neo-Red-P) McCann, Patrick J.; Ager, Casey R.; Obradovic, Aleksandar Z.; Chaimowitz, Matthew G.; Pan, Samuel; Laplaca, Caroline J.; Shah, Parin; Virk, Renu K.; Anderson, Christopher B.; Spina, Catherine S.; Runcie, Karie D.; Stein, Mark N.; Drake, Charles G.; Dallos, Matthew C. Share Save
Discovery and validation of effective combination therapies targeting cell state-specific master regulator vulnerabilities by network-based protein activity inference in diffuse midline glioma Fernandez, Ester Calvo; Tomassoni, Lorenzo; Zhang, Xu; Obradovic, Aleksandar; Laise, Pasquale; Griffin, Aaron T.; Vlahos, Lukas; Wang, Junqiang; Minns, Hanna E.; Morales, Diana V.; Simmons, Christian; Gallito, Matthew; Wei, Hong-Jian; Zhang, Zhiguo; Gartrell, Robyn; Szalontay, Luca; Zacharoulis, Stergios; Wu, Cheng-Chia; Califano, Andrea; Pavisic, Jovana Share Save
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Dynamic establishment of recipient resident memory T cell repertoire after human intestinal transplantation Jiao, Wenyu; Martinez, Mercedes; Muntnich, Constanza Bay; Zuber, Julien; Parks, Christopher; Obradovic, Aleksandar; Tian, Guangyao; Wang, Zicheng; Long, Katherine D.; Waffarn, Elizabeth; Frangaj, Kristjana; Jones, Rebecca; Gorur, Alaka; Shonts, Brittany; Rogers, Kortney; Lv, Guoyue; Velasco, Monica; Ravella, Shilpa; Weiner, Joshua; Kato, Tomoaki; Shen, Yufeng; Fu, Jianing; Sykes, Megan Share Save
Immunomodulatory response to neoadjuvant nivolumab in non-metastatic clear cell renal cell carcinoma Singla, Nirmish; Nirschl, Thomas R.; Obradovic, Aleksandar Z.; Shenderov, Eugene; Lombardo, Kara; Liu, Xiaopu; Pons, Alice; Zarif, Jelani C.; Rowe, Steven P.; Trock, Bruce J.; Hammers, Hans J.; Bivalacqua, Trinity J.; Pierorazio, Phillip M.; Deutsch, Julie S.; Lotan, Tamara L.; Taube, Janis M.; Ged, Yasser M. A.; Gorin, Michael A.; Allaf, Mohamad E.; Drake, Charles G. Share Save
Plasticity of intragraft alloreactive T cell clones in human gut correlates with transplant outcomes Fu, Jianing; Wang, Zicheng; Martinez, Mercedes; Obradovic, Aleksandar; Jiao, Wenyu; Frangaj, Kristjana; Jones, Rebecca; Guo, Xinzheng V.; Zhang, Ya; Kuo, Wan-, I; Ko, Huaibin M.; Iuga, Alina; Bay Muntnich, Constanza; Prada Rey, Adriana; Rogers, Kortney; Zuber, Julien; Ma, Wenji; Miron, Michelle; Farber, Donna L.; Weiner, Joshua; Kato, Tomoaki; Shen, Yufeng; Sykes, Megan Share Save
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A SYSTEMS BIOLOGY APPROACH TO DEFINING AND TARGETING CELL STATE-SPECIFIC MASTER REGULATOR DEPENDENCIES IN DIFFUSE MIDLINE GLIOMA Fernandez, Ester Calvo; Wang, Junqiang; Zhang, Xu; Wei, Hong-Jian; Minns, Hanna; Griffin, Aaron; Obradovic, Aleksandar; Vlahos, Lukas; Martins, Timothy; Becker, Pamela; Crawford, John; Gartrell, Robyn; Szalontay, Luca; Zacharoulis, Stergios; Zhang, Zhiguo; Wechsler-Reya, Robert; Wu, Cheng-Chia; Califano, Andrea; Pavisic, Jovana Share Save
Modeling prostate cancer metastasis in genetically engineered mouse models Abate-Shen, Cory; Giacobbe, Arianna; Obradovic, Aleksandar; Vasciaveo, Alessandro; Picech, Florencia; Ronaldson-Bouchard, Kacey; Vunjak-Novakovic, Gordana; Shen, Michael M.; Califano, Andrea; Sims, Peter Share Save
B7-H3 as a Therapeutic Target in Advanced Prostate Cancer (vol 83, pg 224, 2023) Guo, Christina; Figueiredo, Ines; Gurel, Bora; Neeb, Antje; Seed, George; Crespo, Mateus; Carreira, Suzanne; Rekowski, Jan; Buroni, Lorenzo; Welti, Jon; Bogdan, Denisa; Gallagher, Lewis; Sharp, Adam; de la Maza, Maria D. Fenor; Rescigno, Pasquale; Westaby, Daniel; Chandran, Khobe; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Cali, Bianca; Alimanti, Andrea; Bressan, Silvia; Nguyen, Alana H. T.; Shen, Michael M.; Hawley, Jessica E.; Obradovic, Aleksandar; Drake, Charles G.; Bertan, Claudia; Baker, Chloe; Tunariu, Nina; Yuan, Wei; de Bono, Johann S. Share Save
Li-Fraumeni Syndrome-Associated Dimer-Forming Mutant p53 Promotes Transactivation-Independent Mitochondrial Cell Death Choe, Joshua H.; Kawase, Tatsuya; Xu, An; Guzman, Asja; Obradovic, Aleksandar Z.; Low-Calle, Ana Maria; Alaghebandan, Bita; Raghavan, Ananya; Long, Kaitlin; Hwang, Paul M.; Schiffman, Joshua D.; Zhu, Yan; Zhao, Ruiying; Lee, Dung -Fang; Katz, Chen; Prives, Carol Share Save
Li-Fraumeni syndrome-associated dimer-forming mutant p53 promotes transactivation-independent mitochondrial cell death Choe, Joshua H.; Kawase, Tatsuya; Xu, An; Guzman, Asja; Tong, David R.; Obradovic, Aleksandar Z.; Low-Calle, Ana M.; Alaghebandan, Bita; Raghavan, Ananya; Long, Kaitlin; Hwang, Paul M.; Schiffman, Joshua D.; Zhu, Yan; Zhao, Ruiying; Lee, Dung-Fang; Katz, Chen; Prives, Carol L. Share Save
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