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Multiomic analysis reveals a key BCAT1 role in mTOR activation by B cell receptor and TLR9 Guo, Rui; Sun, Yizhe; Lim, Matthew Y.; Shah, Hardik; Paulo, Joao A.; Ahmed, Rahaman A.; Li, Weixing; Zhang, Yuchen; Yang, Haopeng; Wang, Liang Wei; Strebinger, Daniel; Smith, Nicholas A.; Li, Meng; Leong, Merrin Man Long; Lutchenkov, Michael; Liang, Jin Hua; Li, Zhixuan; Wang, Yin; Puri, Rishi; Melnick, Ari; Green, Michael R.; Asara, John M.; Papathanassiu, Adonia E.; Wesemann, Duane R.; Gygi, Steven P.; Mootha, Vamsi K.; Gewurz, Benjamin E. Share Save
Mutant IDH1 cooperates with NPM1c or FLT3ITD to drive distinct myeloid diseases and molecular outcomes Sakamoto, Takashi; Leca, Julie; Zhang, Xin; Meydan, Cem; Foox, Jonathan; Ramachandran, Parameswaran; Hendrikse, Liam D.; Zhou, Wenjing; Berger, Thorsten; Fortin, Jerome; Chan, Steven M.; Chiang, Ming-Feng; Inoue, Satoshi; Li, Wanda Y.; Chu, Mandy F.; Duncan, Gordon S.; Wakeham, Andrew; Lemonnier, Francois; Tobin, Chantal; Mcwilliam, Ryan; Colonna, Isabelle; Bontoux, Christophe; Jafari, Soode Moghadas; Bowman, Robert L.; Nicolay, Brandon; Ronseaux, Sebastien; Narayanaswamy, Rohini; Levine, Ross L.; Melnick, Ari M.; Mason, Christopher E.; Minden, Mark D. Share Save
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility (vol 15, 9432, 2024) Gao, Vianne R.; Das, Arnav; Luo, Renhe; Luo, Hanzhi; Mcnally, Dylan R.; Karagiannidis, Ioannis; Wang, Zhong-Min; Karbalayghareh, Alireza; Wong, Wilfred; Zhan, Yingqian A.; Chin, Christopher R.; Noble, William S.; Bilmes, Jeff A.; Apostolou, Effie; Kharas, Michael G.; Beguelin, Wendy; Viny, Aaron D.; Huangfu, Danwei; Rudensky, Alexander Y.; Melnick, Ari M.; Leslie, Christina S. Share Save
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Installment of Automation and Modernized Culture Methods Updates a Drug-Sensitivity Screening Platform and Paves the Way to Next-Generation of Precision Medicine Kawabata, Kimihito Cojin; Li, Chao; Kakinuma, Hideaki; Takama, Yoshiharu; Tsuji, Hayato; Komori, Hironobu; Gong, Bo; Kimura, Yasumasa; Tanomura, Hideki; Okamoto, Atsushi; Morita, Maiko; Takamori, Hiroyuki; Fukushima, Hidehito; Yokoyama, Kazuaki; Konuma, Takaaki; Ohno, Nobuhiro; Goyama, Susumu; Yamazaki, Satoshi; Oka, Tetsushi; Kudo, Gen; Melnick, Ari M.; Nannya, Yasuhito; Imoto, Seiya; Takahashi, Satoshi Share Save
Follicular Dendritic Cells Represent a Therapeutic Vulnerability in Early Follicular Lymphoma Gribbin, Caitlin; Mcnally, Dylan; Karagiannidis, Ioannis; Nam, Henna S.; Ravichandran, Hiranmayi; Brauge, Baptiste; Tarte, Karin; Chadburn, Amy; Ouseph, Madhu M.; Carrasco, Sebastian; Steidl, Christian; Scott, David W.; Melnick, Ari M.; Beguelin, Wendy Share Save
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility Gao, Vianne R.; Yang, Rui; Das, Arnav; Luo, Renhe; Luo, Hanzhi; McNally, Dylan R.; Karagiannidis, Ioannis; Rivas, Martin A.; Wang, Zhong-Min; Barisic, Darko; Karbalayghareh, Alireza; Wong, Wilfred; Zhan, Yingqian A.; Chin, Christopher R.; Noble, William S.; Bilmes, Jeff A.; Apostolou, Effie; Kharas, Michael G.; Beguelin, Wendy; Viny, Aaron D.; Huangfu, Danwei; Rudensky, Alexander Y.; Melnick, Ari M.; Leslie, Christina S. Share Save
SETD1B mutations confer apoptosis resistance and BCL2 independence in B cell lymphoma Portelinha, Ana; Wang, Shenqiu; Parsa, Sara; Jiang, Man; Gorelick, Alexander N.; Mohanty, Sagarajit; Sharma, Soumya; de Stanchina, Elisa; Berishaj, Marjan; Zhao, Chunying; Heward, James; Aryal, Neeraj K.; Tavana, Omid; Wen, Jiayu; Fitzgibbon, Jude; Dogan, Ahmet; Younes, Anas; Melnick, Ari M.; Wendel, Hans-Guido Share Save
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Profiling Dynamic Patterns of Single-Cell Motility Maity, Debonil; Sivakumar, Nikita; Kamat, Pratik; Zamponi, Nahuel; Min, Chanhong; Du, Wenxuan; Jayatilaka, Hasini; Johnston, Adrian; Starich, Bartholomew; Agrawal, Anshika; Riley, Deanna; Venturutti, Leandro; Melnick, Ari; Cerchietti, Leandro; Walston, Jeremy; Phillip, Jude M. Share Save
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight Kim, JangKeun; Tierney, Braden T.; Overbey, Eliah G.; Dantas, Ezequiel; Fuentealba, Matias; Park, Jiwoon; Narayanan, S. Anand; Wu, Fei; Najjar, Deena; Chin, Christopher R.; Meydan, Cem; Loy, Conor; Mathyk, Begum; Klotz, Remi; Ortiz, Veronica; Nguyen, Khiem; Ryon, Krista A.; Damle, Namita; Houerbi, Nadia; Patras, Laura I.; Schanzer, Nathan; Hutchinson, Gwyneth A.; Foox, Jonathan; Bhattacharya, Chandrima; Mackay, Matthew; Afshin, Evan E.; Hirschberg, Jeremy Wain; Kleinman, Ashley S.; Schmidt, Julian C.; Schmidt, Caleb M.; Schmidt, Michael A.; Beheshti, Afshin; Matei, Irina; Lyden, David; Mullane, Sean; Asadi, Amran; Lenz, Joan S.; Mzava, Omary; Yu, Min; Ganesan, Saravanan; De Vlaminck, Iwijn; Melnick, Ari M.; Barisic, Darko; Winer, Daniel A.; Zwart, Sara R.; Crucian, Brian E.; Smith, Scott M.; Mateus, Jaime; Furman, David; Mason, Christopher E. Share Save
Molecular and physiological changes in the SpaceX Inspiration4 civilian crew Jones, Christopher W.; Overbey, Eliah G.; Lacombe, Jerome; Ecker, Adrian J.; Meydan, Cem; Ryon, Krista; Tierney, Braden; Damle, Namita; Mackay, Matthew; Afshin, Evan E.; Foox, Jonathan; Park, Jiwoon; Nelson, Theodore M.; Mohamad, Mir Suhail; Byhaqui, Syed Gufran Ahmad; Aslam, Burhan; Tali, Ummer Akbar; Nisa, Liaqun; Menon, Priya V.; Patel, Chintan O.; Khan, Sharib A.; Ebert, Doug J.; Everson, Aaron; Schubert, Michael C.; Ali, Nabila N.; Sarma, Mallika S.; Kim, Jangkeun; Houerbi, Nadia; Grigorev, Kirill; Medina, J. Sebastian Garcia; Summers, Alexander J.; Gu, Jian; Altin, John A.; Fattahi, Ali; Hirzallah, Mohammad I.; Wu, Jimmy H.; Stahn, Alexander C.; Beheshti, Afshin; Klotz, Remi; Ortiz, Veronica; Yu, Min; Patras, Laura; Matei, Irina; Lyden, David; Melnick, Ari; Banerjee, Neil; Mullane, Sean; Kleinman, Ashley S.; Loesche, Michael; Menon, Anil S.; Donoviel, Dorit B.; Urquieta, Emmanuel; Mateus, Jaime; Sargsyan, Ashot E.; Shelhamer, Mark; Zenhausern, Frederic; Bershad, Eric M.; Basner, Mathias; Mason, Christopher E. Share Save
Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses Grigorev, Kirill; Nelson, Theodore M.; Overbey, Eliah G.; Houerbi, Nadia; Kim, Jangkeun; Najjar, Deena; Damle, Namita; Afshin, Evan E.; Ryon, Krista A.; Thierry-Mieg, Jean; Thierry-Mieg, Danielle; Melnick, Ari M.; Mateus, Jaime; Mason, Christopher E. Share Save
Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment Li, Jie; Chin, Christopher R.; Ying, Hsia-Yuan; Meydan, Cem; Teater, Matthew R.; Xia, Min; Farinha, Pedro; Takata, Katsuyoshi; Chu, Chi-Shuen; Jiang, Yiyue; Eagles, Jenna; Passerini, Verena; Tang, Zhanyun; Rivas, Martin A.; Weigert, Oliver; Pugh, Trevor J.; Chadburn, Amy; Steidl, Christian; Scott, David W.; Roeder, Robert G.; Mason, Christopher E.; Zappasodi, Roberta; Beguelin, Wendy; Melnick, Ari M. Share Save
Integrative analysis identifies an older female-linked AML patient group with better risk in ECOG-ACRIN Cancer Research Group's clinical trial E3999 (vol 12, 137,2022) Rapaport, Franck; Seier, Kenneth; Neelamraju, Yaseswini; Hassane, Duane; Baslan, Timour; Gildea, Daniel T.; Haddox, Samuel; Lee, Tak; Murdock, H. Moses; Sheridan, Caroline; Thurmond, Alexis; Wang, Ling; Carroll, Martin; Cripe, Larry D.; Fernandez, Hugo; Mason, Christopher E.; Paietta, Elisabeth; Roboz, Gail J.; Sun, Zhuoxin; Tallman, Martin S.; Zhang, Yanming; Gonen, Mithat; Levine, Ross; Melnick, Ari M.; Kleppe, Maria; Garrett-Bakelman, Francine E. Share Save
The promyelocytic leukemia zinc finger protein affects myeloid cell growth, differentiation, and apoptosis Shaknovich, R; Yeyati, PL; Ivins, S; Melnick, A; Lempert, C; Waxman, S; Zelent, A; Licht, JD Share Save
Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas Shah, Shivem B.; Carlson, Christopher R.; Lai, Kristine; Zhong, Zhe; Marsico, Grazia; Lee, Katherine M.; Felix Velez, Nicole E.; Abeles, Elisabeth B.; Allam, Mayar; Hu, Thomas; Walter, Lauren D.; Martin, Karen E.; Gandhi, Khanjan; Butler, Scott D.; Puri, Rishi; McCleary-Wheeler, Angela L.; Tam, Wayne; Elemento, Olivier; Takata, Katsuyoshi; Steidl, Christian; Scott, David W.; Fontan, Lorena; Ueno, Hideki; Cosgrove, Benjamin D.; Inghirami, Giorgio; Garcia, Andres J.; Coskun, Ahmet F.; Koff, Jean L.; Melnick, Ari; Singh, Ankur Share Save
Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells Fortin, Jerome; Chiang, Ming-Feng; Meydan, Cem; Foox, Jonathan; Ramachandran, Parameswaran; Leca, Julie; Lemonnier, Francois; Li, Wanda Y.; Gams, Miki S.; Sakamoto, Takashi; Chu, Mandy; Tobin, Chantal; Laugesen, Eric; Robinson, Troy M.; You-Ten, Annick; Butler, Daniel J.; Berger, Thorsten; Minden, Mark D.; Levine, Ross L.; Guidos, Cynthia J.; Melnick, Ari M.; Mason, Christopher E.; Mak, Tak W. Share Save
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