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SaveTherapeutic targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results
Crespo-Garcia, Sergio; Fournier, Frederik; Diaz-Marin, Roberto; Klier, Sharon; Ragusa, Derek; Masaki, Lauren; Cagnone, Gael; Blot, Guillaume; Hafiane, Ikhlas; Dejda, Agnieszka; Rizk, Rana; Juneau, Rachel; Buscarlet, Manuel; Chorfi, Sarah; Patel, Priyanka; Beltran, Pedro J.; Joyal, Jean-Sebastien; Rezende, Flavio A.; Hata, Masayuki; Nguyen, Alex; Sullivan, Lynne; Damiano, Jason; Wilson, Ariel M.; Mallette, Frederick A.; David, Nathaniel E.; Ghosh, Anirvan; Tsuruda, Pamela R.; Dananberg, Jamie; Sapieha, Przemyslaw Share Save Organ dysfunction, thrombotic events, and malignancies in patients with idiopathic multicentric Castleman disease: a population-level US health claims analysis (vol 36, pg 2539, 2022)Mukherjee, Sudipto; Kanhai, Karan; Kauffman, David; Martin, Rabecka; Paige, Jeremy S.; Ghosh, Anirvan; Kannan, Hannah; Shupo, Francis; Fajgenbaum, David C. Share Save Organ dysfunction, thrombotic events and malignancies in patients with idiopathic multicentric castleman disease: a population-level US health claims analysisMukherjee, Sudipto; Kanhai, Karan; Kauffman, David; Martin, Rabecka; Paige, Jeremy S.; Ghosh, Anirvan; Kannan, Hannah; Shupo, Francis; Fajgenbaum, David C. Share Save Share Save Evaluation of Smartphone-Based Testing to Generate Exploratory Outcome Measures in a Phase 1 Parkinson's Disease Clinical TrialLipsmeier, Florian; Taylor, Kirsten I.; Kilchenmann, Timothy; Wolf, Detlef; Scotland, Alf; Schjodt-Eriksen, Jens; Cheng, Wei-Yi; Fernandez-Garcia, Ignacio; Siebourg-Polster, Juliane; Jin, Liping; Soto, Jay; Verselis, Lynne; Boess, Frank; Koller, Martin; Grundman, Michael; Monsch, Andreas U.; Postuma, Ronald B.; Ghosh, Anirvan; Kremer, Thomas; Czech, Christian; Gossens, Christian; Lindemann, Michael Share Save Share Save Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like PathologySavas, Jeffrey N.; Wang, Yi-Zhi; DeNardo, Laura A.; Martinez-Bartolome, Salvador; McClatchy, Daniel B.; Hark, Timothy J.; Shanks, Natalie F.; Cozzolino, Kira A.; Lavallee-Adam, Mathieu; Smukowski, Samuel N.; Park, Sung Kyu; Kelly, Jeffery W.; Koo, Edward H.; Nakagawa, Terunaga; Masliah, Eliezer; Ghosh, Anirvan; Yates, John R., III Share Save Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexesStaahl, Brett T.; Benekareddy, Madhurima; Coulon-Bainier, Claire; Banfal, Ashwin A.; Floor, Stephen N.; Sabo, Jennifer K.; Urnes, Cole; Munares, Gabriela Acevedo; Ghosh, Anirvan; Doudna, Jennifer A. Share Save mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous SclerosisCosta, Veronica; Aigner, Stefan; Vukcevic, Mirko; Sauter, Evelyn; Behr, Katharina; Ebeling, Martin; Dunkley, Tom; Friedlein, Arno; Zoffmann, Sannah; Meyer, Claas A.; Knoflach, Frederic; Lugert, Sebastian; Patsch, Christoph; Fjeldskaar, Fatiha; Chicha-Gaudimier, Laurie; Kiialainen, Anna; Piraino, Paolo; Bedoucha, Marc; Graf, Martin; Jessberger, Sebastian; Ghosh, Anirvan; Bischofberger, Josef; Jagasia, Ravi Share Save Share Save The intellectual disability gene Kirrel3 regulates target-specific mossy fiber synapse development in the hippocampusMartin, E. Anne; Muralidhar, Shruti; Wang, Zhirong; Cervantes, Diego Cordero; Basu, Raunak; Taylor, Matthew R.; Hunter, Jennifer; Cutforth, Tyler; Wilke, Scott A.; Ghosh, Anirvan; Williams, Megan E. Share Save Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum DisorderBrunner, Daniela; Kabitzke, Patricia; He, Dansha; Cox, Kimberly; Thiede, Lucinda; Hanania, Taleen; Sabath, Emily; Alexandrov, Vadim; Saxe, Michael; Peles, Elior; Mills, Alea; Spooren, Will; Ghosh, Anirvan; Feliciano, Pamela; Benedetti, Marta; Clayton, Alice Luo; Biemans, Barbara Share Save The Sorting Receptor SorCS1 Regulates Trafficking of Neurexin and AMPA ReceptorsSavas, Jeffrey N.; Ribeiro, Luis F.; Wierda, Keimpe D.; Wright, Rebecca; DeNardo-Wilke, Laura A.; Rice, Heather C.; Chamma, Ingrid; Wang, Yi-Zhi; Zemla, Roland; Lavallee-Adam, Mathieu; Vennekens, Kristel M.; O'Sullivan, Matthew L.; Antonios, Joseph K.; Hall, Elizabeth A.; Thoumine, Olivier; Attie, Alan D.; Yates, John R., III; Ghosh, Anirvan; de Wit, Joris Share Save Share Save Share Save Share Save Share Save Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular ShuttleNiewoehner, Jens; Bohrmann, Bernd; Collin, Ludovic; Urich, Eduard; Sade, Hadassah; Maier, Peter; Rueger, Petra; Stracke, Jan Olaf; Lau, Wilma; Tissot, Alain C.; Loetscher, Hansruedi; Ghosh, Anirvan; Freskgard, Per-Ola Share Save Share Save 
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