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M

Michael B. Sporn

IRCCS Multimedica

151H-index
785Paper Count
9.1WCitation Count
Published Papers 106
Publication Date
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The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma
errMOLECULAR ONCOLOGY
IF4.5
err2023-06-13
err1
errOAAI
errLuo, George; Aldridge, Kristin; Chen, Toby; Aslot, Vivek; Kim, Byung-Gyu; Han, Eun Hyang; Singh, Neelima; Li, Sai; Xiao, Tsan Sam; Sporn, Michael B.; Letterio, John J.
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Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-03
err19
errOAAI
errZhang, Anqi; Suzuki, Takafumi; Adachi, Saki; Naganuma, Eriko; Suzuki, Norio; Hosoya, Tomonori; Itoh, Ken; Sporn, Michael B.; Yamamoto, Masayuki
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Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2022-08-01
err13
errOAAI
errWakamori, Shun; Taguchi, Keiko; Nakayama, Yuki; Ohkoshi, Akira; Sporn, Michael B.; Ogawa, Takenori; Katori, Yukio; Yamamoto, Masayuki
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CDDO-imidazolide Targets Multiple Amino Acid Residues on the Nrf2 Adaptor, Keap1
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-07-31
err32
PREAI
errMeng, Xiaoli; Waddington, James C.; Tailor, Arun; Lister, Adam; Hamlett, Jane; Berry, Neil; Park, B. Kevin; Sporn, Michael B.
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RETRACTION: Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis (Retraction of Vol 20, Pg 446, 2012)
errOSTEOARTHRITIS AND CARTILAGE
IF9
err2020-06-01
err0
errOAAI
errSuh, N.; Paul, S.; Lee, H. J.; Yoon, T.; Shah, N.; Son, A. I.; Reddi, A. H.; Medici, D.; Sporn, M. B.
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errSave
Retinoid X receptor agonist LG100268 modulates the immune microenvironment in preclinical breast cancer models
errNPJ BREAST CANCER
IF7.6
err2019-11-01
err27
errOAAI
errLeal, Ana S.; Zydeck, Kayla; Carapellucci, Sarah; Reich, Lyndsey A.; Zhang, Di; Moerland, Jessica A.; Sporn, Michael B.; Liby, Karen T.
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The rexinoid LG100268 decreases immunosuppressive immune cells and activates T cells in two preclinical models of breast cancer
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errLeal, Ana Sofia; Carapellucci, Sarah; ZydecK, Kayla; Sporn, Michael B.; Liby, Karen T.
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The rexinoid LG100268 modulates immune cell populations in mammary gland tumors of MMTV-neu mice
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errLeal, Ana Sofia; Carapellucci, Sarah; Zydeck, Kayla; Raychaudhuri, Nupur; Sporn, Michael B.; Liby, Karen T.
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Evaluation of new rexinoids for lung cancer
errCANCER RESEARCH
IF16.6
err2017-07-01
err0
PREAI
errZhang, Di; Leal, Ana S.; Carapellucci, Sarah E.; Zydeck, Kayla; Chaaban, Nicole; Sporn, Michael B.; Wagner, Carl E.; Liby, Karen T.
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Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer
errCANCER LETTERS
IF10.1
err2017-05-01
err102
PREAI
errLeal, Ana S.; Williams, Charlotte R.; Royce, Darlene B.; Pioli, Patricia A.; Sporn, Michael B.; Liby, Karen T.
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The synthetic triterpenoid CDDO-Imidazolide reduces immune cell infiltration and cytokine secretion in the KC mouse model of pancreatic cancer
errCANCER RESEARCH
IF16.6
err2016-12-14
err0
PREAI
errLeal, Ana Sofia; Sporn, Michael B.; Pioli, Patricia A.; Liby, Karen T.
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The triterpenoid CDDO-imidazolide reduces immune cell infiltration and cytokine secretion in the KrasG12D;Pdx1-Cre (KC) mouse model of pancreatic cancer
errCARCINOGENESIS
IF2.9
err2016-09-22
err13
errOAAI
errLeal, Ana S.; Sporn, Michael B.; Pioli, Patricia A.; Liby, Karen T.
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Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention
errPHARMACOLOGICAL RESEARCH
IF10.5
err2015-10-01
err25
PREAI
errCao, Martine; Onyango, Evans O.; Williams, Charlotte R.; Royce, Darlene B.; Gribble, Gordon W.; Sporn, Michael B.; Liby, Karen T.
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Therapeutic effects of the bromodomain inhibitors JQ1 and I-BET 762 on pancreatic cancer
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errLeal, Ana S.; Williams, Charlotte R.; Sporn, Michael B.; Liby, Karen T.
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errSave
Comparison of oleanane triterpenoids and dimethyl fumarate in lung cancer
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errTo, Ciric; Royce, Darlene B.; Williams, Charlotte R.; Risingsong, Renee; Sporn, Michael B.; Liby, Karen T.
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errSave
Novel synthetic pyridyl analogues of CDDO-Im with improved stability and their potential use in cancer prevention
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errCao, Martine; Onyango, Evans; Williams, Charlotte; Royce, Darlene; Gribble, Gordon; Sporn, Michael; Liby, Karen
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errSave
Immunomodulatory properties of bromodomain inhibitors in pancreatic cancer cells
errCANCER RESEARCH
IF16.6
err2015-06-30
err0
PREAI
errLeal, Ana S.; Williams, Charlotte R.; Sporn, Michael B.; Liby, Karen T.
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errSave
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis
errCARCINOGENESIS
IF2.9
err2015-05-04
err60
errOAAI
errTo, Ciric; Ringelberg, Carol S.; Royce, Darlene B.; Williams, Charlotte R.; Risingsong, Renee; Sporn, Michael B.; Liby, Karen T.
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errSave
c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells
errCANCER BIOLOGY & THERAPY
IF4.6
err2014-10-28
err63
errOAAI
errZou, Wei; Chen, Shuzhen; Liu, Xiangguo; Yue, Ping; Sporn, Michael B.; Khuri, Fadlo R.; Sun, Shi-Yong
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Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO
errCANCER BIOLOGY & THERAPY
IF4.6
err2014-10-27
err47
errOAAI
errAlabran, Jennifer L.; Cheuk, Adam; Liby, Karen; Sporn, Michael; Khan, Javed; Letterio, John; Leskov, Konstantin S.
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Research Directions

No research directions
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