Not logged in Sequence tolerance of immunoglobulin variable domain framework regions to noncanonical intradomain disulfide linkages Kim, Dae Young; Kandalaft, Hiba; Lowden, Michael J.; Yang, Qingling; Rossotti, Martin A.; Robotham, Anna; Kelly, John F.; Hussack, Greg; Schrag, Joseph D.; Henry, Kevin A.; Tanha, Jamshid Share Save
Influence of variant-specific mutations, temperature and pH on conformations of a large set of SARS-CoV-2 spike trimer vaccine antigen candidates Stuible, Matthew; Schrag, Joseph D.; Sheff, Joey; Zoubchenok, Daria; Lord-Dufour, Simon; Cass, Brian; L'Abbe, Denis; Pelletier, Alex; Rossotti, Martin A.; Tanha, Jamshid; Gervais, Christian; Maurice, Roger; El Bakkouri, Majida; Acchione, Mauro; Durocher, Yves Share Save
Structure-guided design of a potent Clostridioides difficile toxin A inhibitor (vol 14, 1110541, 2023) Hussack, Greg; Rossotti, Martin A.; van Faassen, Henk; Murase, Tomohiko; Eugenio, Luiz; Schrag, Joseph D.; Ng, Kenneth K. -S.; Tanha, Jamshid Share Save
A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens Joubert, Simon; Stuible, Matthew; Lord-Dufour, Simon; Lamoureux, Linda; Vaillancourt, Francois; Perret, Sylvie; Ouimet, Manon; Pelletier, Alex; Bisson, Louis; Mahimkar, Rohan; Pham, Phuong Lan; L'Ecuyer-Coelho, Helene; Roy, Marjolaine; Voyer, Robert; Baardsnes, Jason; Sauvageau, Janelle; St-Michael, Frank; Robotham, Anna; Kelly, John; Acel, Andrea; Schrag, Joseph D.; El Bakkouri, Majida; Durocher, Yves Share Save
An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity Weisser, Nina E.; Sanches, Mario; Escobar-Cabrera, Eric; O'Toole, Jason; Whalen, Elizabeth; Chan, Peter W. Y.; Wickman, Grant; Abraham, Libin; Choi, Kate; Harbourne, Bryant; Samiotakis, Antonios; Rojas, Andrea Hernandez; Volkers, Gesa; Wong, Jodi; Atkinson, Claire E.; Baardsnes, Jason; Worrall, Liam J.; Browman, Duncan; Smith, Emma E.; Baichoo, Priya; Cheng, Chi Wing; Guedia, Joy; Kang, Sohyeong; Mukhopadhyay, Abhishek; Newhook, Lisa; Ohrn, Anders; Raghunatha, Prajwal; Zago-Schmitt, Matteo; Schrag, Joseph D.; Smith, Joel; Zwierzchowski, Patricia; Scurll, Joshua M.; Fung, Vincent; Black, Sonia; Strynadka, Natalie C. J.; Gold, Michael R.; Presta, Leonard G.; Ng, Gordon; Dixit, Surjit Share Save
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Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment Sulea, Traian; Rohani, Nazanin; Baardsnes, Jason; Corbeil, Christopher R.; Deprez, Christophe; Cepero-Donates, Yuneivy; Robert, Alma; Schrag, Joseph D.; Parat, Marie; Duchesne, Melanie; Jaramillo, Maria L.; Purisima, Enrico O.; Zwaagstra, John C. Share Save
Binding symmetry and surface flexibility mediate antibody self-association Schrag, Joseph D.; Picard, Marie-Eve; Gaudreault, Francis; Gagnon, Louis-Patrick; Baardsnes, Jason; Manenda, Mahder S.; Sheff, Joey; Deprez, Christophe; Baptista, Cassio; Hogues, Herve; Kelly, John F.; Purisima, Enrico O.; Shi, Rong; Sulea, Traian Share Save
Development of novel formats of anti-AXL ADCs Jaramillo, Maria L.; Banville, Myriam; Robert, Alma; Meury, Luc; Acchione, Maurizio; Marcil, Anne; Gadoury, Christine; Wu, Cunle; Fortin, Yves; Henry, Kevin; Schrag, Joseph; The-Minh Tu; Ling, Binbing (Erica); Slinn, Jacqueline; Moreno, Maria Share Save
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Antibody light chain variable domains and their biophysically improved versions for human immunotherapy Kim, Dae Young; To, Rebecca; Kandalaft, Hiba; Ding, Wen; van Faassen, Henk; Luo, Yan; Schrag, Joseph D.; St-Amant, Nadereh; Hefford, Mary; Hirama, Tomoko; Kelly, John F.; MacKenzie, Roger; Tanha, Jamshid Share Save
Structural and enzymatic characterization of NanS (YjhS), a 9-O-Acetyl N-acetylneuraminic acid esterase from Escherichia coli O157:H7 Rangarajan, Erumbi S.; Ruane, Karen M.; Proteau, Ariane; Schrag, Joseph D.; Valladares, Ricardo; Gonzalez, Claudio F.; Gilbert, Michel; Yakunin, Alexander F.; Cygler, Miroslaw Share Save
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