Not logged in Design, Structure-Activity Relationships, and Computational Modeling Studies of a Series of α-Helix Biased, Ultra-Short Glucagon-like Peptide-1 Receptor Agonists Sawyer, Jonathon R.; Audie, Joseph A.; Swanson, Jon; Diller, David; Santiago, Solimar; Gribkoff, Valentin K.; Ackerman, Allison; Hruby, Victor J.; Gobbo, Gianpaolo; Bellucci, Michael A.; Glauser, William A.; Pentelute, Brad L.; Sawyer, Tomi K. Share Save
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Mitochondria and Memory: Bioenergetics, Synaptic Plasticity and Neurodegeneration Jonas, Elizabeth A.; Mnatsakanyan, Nelli; Miranda, Paige; Park, Han-A; Chen, Rongmin; Licznerski, Pawel; Weinert, Maria; Smith, Peter J. S.; Chavez, Andres; Zukin, R. Suzanne; Gribkoff, Valentin K.; Alavian, Kambiz N. Share Save
The Mitochondrial Complex V-Associated Large-Conductance Inner Membrane Current Is Regulated by Cyclosporine and Dexpramipexole Alavian, Kambiz N.; Dworetzky, Steven I.; Bonanni, Laura; Zhang, Ping; Sacchetti, Silvio; Li, Hongmei; Signore, Armando P.; Smith, Peter J. S.; Gribkoff, Valentin K.; Jonas, Elizabeth A. Share Save
The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis Cudkowicz, Merit; Bozik, Michael E.; Ingersoll, Evan W.; Miller, Robert; Mitsumoto, Hiroshi; Shefner, Jeremy; Moore, Dan H.; Schoenfeld, David; Mather, James L.; Archibald, Donald; Sullivan, Mary; Amburgey, Craig; Moritz, Juliet; Gribkoff, Valentin K. Share Save
Atropisomeric 3-(β-hydroxyethyl)-4-arylquinolin-2-ones as maxi-K potassium channel openers Vrudhula, Vivekananda M.; Dasgupta, Bireshwar; Qian-Cutrone, Jingfang; Kozlowski, Edward S.; Boissard, Christopher G.; Dworetzky, Steven I.; Wu, Dedong; Gao, Qi; Kimura, Roy; Gribkoff, Valentin K.; Starrett, John E., Jr. Share Save
3-[(5-chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one, BMS-191011:: Opener of large-conductance Ca2+-activated potassium (Maxi-K) channels, identification, solubility, and SAR Romine, Jeffrey L.; Martin, Scott W.; Meanwell, Nicholas A.; Gribkoff, Valentin K.; Boissard, Christopher G.; Dworetzky, Steven I.; Natale, Joanne; Moon, Sandra; Ortiz, Astrid; Yeleswaram, Swamy; Pajor, Lorrane; Gao, Qi; Starrett, John E., Jr. Share Save
Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping Lindner, Mark D.; Hogan, John B.; Hodges, Donald B., Jr.; Orie, Anitra F.; Chen, Ping; Corsa, Jason A.; Leet, John E.; Gillman, Kevin W.; Rose, Gregory M.; Jones, Kelli M.; Gribkoff, Valentin K. Share Save
Synthesis and structure-activity relationship of acrylamides as KCNQ2 potassium channel openers Wu, YJ; He, H; Sun, LQ; L'Heureux, A; Chen, J; Dextraze, P; Starrett, JE; Boissard, CG; Gribkoff, VK; Natale, J; Dworetzky, SI Share Save
An assessment of the effects of serotonin 6 (5-HT6) receptor antagonists in rodent models of learning Lindner, MD; Hodges, DB; Hogan, JB; Orie, AF; Corsa, JA; Barten, DM; Polson, C; Robertson, BJ; Guss, VL; Gillman, KW; Starrett, JE; Gribkoff, VK Share Save
(S)-N-[1-(3-Morpholin-4-ylphenyl)ethyl]-3phenylacrylamide:: An orally bioavailable KCNQ2 opener with significant activity in a cortical spreading depression model of migraine Wu, YJ; Boissard, CG; Greco, C; Gribkoff, VK; Harden, DG; He, H; L'Heureux, A; Kang, SH; Kinney, GG; Knox, RJ; Natale, J; Newton, AE; Lehtinen-Oboma, S; Sinz, MW; Sivarao, DV; Starrett, JE; Sun, LQ; Tertyshnikova, S; Thompson, MW; Weaver, D; Wong, HS; Zhang, L; Dworetzky, SL Share Save
4-aryl-3-(hydroxyalkyl)quinolin-2-ones: Novel maxi-K channel opening relaxants of corporal smooth muscle targeted for erectile dysfunction Hewawasam, P; Fan, WH; Ding, M; Flint, M; Cook, D; Goggins, GD; Myers, RA; Gribkoff, VK; Boissard, CG; Dworetzky, SI; Starrett, JE; Lodge, NJ Share Save
4,5-diphenyltriazol-3-ones:: Openers of large-conductance Ca2+-activated potassium (maxi-K) channels Romine, JL; Martin, SW; Gribkoff, VK; Boissard, CG; Dworetzky, SI; Natale, J; Li, Y; Gao, Q; Meanwell, NA; Starrett, JE Share Save
Synthesis and structure-activity relationships of 3-aryloxindoles: A new class of calcium-dependent, large conductance potassium (maxi-K) channel openers with neuroprotective properties Hewawasam, P; Erway, M; Moon, SL; Knipe, J; Weiner, H; Boissard, CG; Post-Munson, DJ; Gao, Q; Huang, S; Gribkoff, VK; Meanwell, NA Share Save
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Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels Gribkoff, VK; Starrett, JE; Dworetzky, SI; Hewawasam, P; Boissard, CG; Cook, DA; Frantz, SW; Heman, K; Hibbard, JR; Huston, K; Johnson, G; Krishnan, BS; Kinney, GG; Lombardo, LA; Meanwell, NA; Molinoff, PB; Myers, RA; Moon, SL; Ortiz, A; Pajor, L; Pieschl, RL; Post-Munson, DJ; Signor, LJ; Srinivas, N; Taber, MT; Thalody, G; Trojnacki, JT; Wiener, H; Yeleswaram, K; Yeola, SW Share Save
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