Not logged in LONGITUDINAL DNA METHYLATION CHANGE FUELS DISEASE PROGRESSION THROUGH ALTERED CELL STATE DIFFERENTIATION IN IDH-MUTANT GLIOMA Nomura, Masashi; Ravirum, Ramya; Schiffman, Joshua S.; Bussema, Lillian; Lu, Vivian; Wheeler, Noelle; Lee, John; Fan, Yilin; Zheng, Mian Hua; Ruiz, Florian; Danish, Husain; Kellet, Sorcha; Nusrat, Labeeba; Chaligne, Ronan; Huse, Jason T.; Yung, W. K. Alfred; Tanaka, Shota; Saito, Nobuhito; Potenski, Catherine; Das, Sunit; Landau, Dan A.; Suva, Mario L. Share Save
DECIPHERING THE LONGITUDINAL TRAJECTORIES OF GLIOBLASTOMA ECOSYSTEMS BY INTEGRATIVE SINGLE-CELL GENOMICS Spitzer, A.; Johnson, K.; Nomura, M.; Garofano, L.; Nehar-Belaid, D.; Galili Darnell, N.; Greenwald, A.; Bussema, L.; Oh, Y.; Varn, F. S.; D'Angelo, F.; Gritsch, S.; Anderson, K. J.; Migliozzi, S.; Gonzalez Castro, L.; Chowdhury, T.; Robine, N.; Reeves, C.; Park, J.; Lipsa, A.; Hertel, F.; Golebiewska, A.; Niclou, S.; Nusrat, L.; Kellett, S.; Das, S.; Moon, H.; Paek, S.; Bielle, F.; Laurenge, A.; Di Stefano, A.; Mathon, B.; Picca, A.; Sanson, M.; Tanaka, S.; Saito, N.; Ashley, D. M.; Keir, S. T.; Ligon, K. L.; Huse, J. T.; Yung, W.; Lasorella, A.; Iavarone, A.; Verhaak, R.; Tirosh, I; Suva, M. L. Share Save
THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION Liu, Ilon; Jiang, Li; Samuelsson, Erik; Salas, Sergio Marco; Beck, Alexander; Hack, Olivia; Jeong, Daeun; Shaw, McKenzie; Englinger, Bernhard; LaBelle, Jenna; Mire, Hafsa; Madlener, Sibylle; Mayr, Lisa; Quezada, Michael; Trissal, Maria; Panditharatna, Eshini; Ernst, Kati; Vogelzang, Jayne; Gatesman, Taylor; Halbert, Matthew; Palova, Hana; Vesela, Petra; Sterba, Jaroslav; Slaby, Ondrej; Geyeregger, Rene; Diaz, Aaron; Findlay, Izac; Dun, Matt; Resnick, Adam; Suva, Mario; Jones, David; Agnihotri, Sameer; Ostlin, Jessica; Koschmann, Carl; Haberler, Christine; Czech, Thomas; Slavc, Irene; Cotter, Jennifer; Ligon, Keith; Alexandrescu, Sanda; Yung, W. K. Alfred; Arrillaga-Romany, Isabel; Gojo, Johannes; Monje, Michelle; Nilsson, Mats; Filbin, Mariella Share Save
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location Liu, Ilon; Jiang, Li; Samuelsson, Erik R.; Salas, Sergio Marco; Beck, Alexander; Hack, Olivia A.; Jeong, Daeun; Shaw, McKenzie L.; Englinger, Bernhard; LaBelle, Jenna; Mire, Hafsa M.; Madlener, Sibylle; Mayr, Lisa; Quezada, Michael A.; Trissal, Maria; Panditharatna, Eshini; Ernst, Kati J.; Vogelzang, Jayne; Gatesman, Taylor A.; Halbert, Matthew E.; Palova, Hana; Pokorna, Petra; Sterba, Jaroslav; Slaby, Ondrej; Geyeregger, Rene; Diaz, Aaron; Findlay, Izac J.; Dun, Matthew D.; Resnick, Adam; Suva, Mario L.; Jones, David T. W.; Agnihotri, Sameer; Svedlund, Jessica; Koschmann, Carl; Haberler, Christine; Czech, Thomas; Slavc, Irene; Cotter, Jennifer A.; Ligon, Keith L.; Alexandrescu, Sanda; Yung, W. K. Alfred; Arrillaga-Romany, Isabel; Gojo, Johannes; Monje, Michelle; Nilsson, Mats; Filbin, Mariella G. Share Save
THE LANDSCAPE OF TUMOR CELL STATES AND SPATIAL ORGANIZATION IN H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA ACROSS AGE AND LOCATION Liu, I; Jiang, L.; Samuelsson, E.; Marco Salas, S.; Hack, O.; Jeong, D.; Shaw, M.; Englinger, B.; LaBelle, J.; Ernst, K.; Palova, H.; Pokorna, P.; Sterba, J.; Slaby, O.; Geyeregger, R.; Jones, D.; Koschmann, C.; Svedlund, J.; Resnick, A.; Diaz, A.; Haberler, C.; Czech, T.; Slavc, I; Cotter, J.; Ligon, K.; Alexandrescu, S.; Yung, W.; Arrillaga-Romany, I; Suva, M.; Beck, A.; Gojo, J.; Monje, M.; Nilsson, M.; Filbin, M. Share Save
EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma Ding, Jie; Li, Xiaolong; Khan, Sabbir; Zhang, Chen; Gao, Feng; Sen, Shayak; Wasylishen, Amanda R.; Zhao, Yang; Lozano, Guillermina; Koul, Dimpy; Alfred Yung, W. K. Share Save
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Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-9 experience Lee, Eudocia Q.; Selig, Wendy; Meehan, Clair; Bacha, Jeffrey; Barone, Amy; Bloomquist, Erik; Chang, Susan M.; de Groot, John F.; Galanis, Evanthia; Hassan, Islam; Kalidas, Chitkala; Khasraw, Mustafa; Kvedar, Joseph C.; Lassman, Andrew B.; Puduvalli, Vinay; Sahebjam, Solmaz; Schwamm, Lee H.; Tamir, Sharon; Welch, Mary; Yung, W. K. Alfred; Zadeh, Gelareh; Arons, David; Wen, Patrick Y. Share Save
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Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation Noureen, Nighat; Wu, Shaofang; Lv, Yingli; Yang, Juechen; Yung, W. K. Alfred; Gelfond, Jonathan; Wang, Xiaojing; Koul, Dimpy; Ludlow, Andrew; Zheng, Siyuan Share Save
Radiographic read paradigms and the roles of the central imaging laboratory in neuro-oncology clinical trials Ellingson, Benjamin M.; Brown, Matthew S.; Boxerman, Jerrold L.; Gerstner, Elizabeth R.; Kaufmann, Timothy J.; Cole, Patricia E.; Bacha, Jeffrey A.; Leung, David; Barone, Amy; Colman, Howard; van den Bent, Martin J.; Wen, Patrick Y.; Yung, W. K. Alfred; Cloughesy, Timothy F.; Goldin, Jonathan G. Share Save
Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02 Chen, Huanwen; Kuhn, John; Lamborn, Kathleen R.; Abrey, Lauren E.; DeAngelis, Lisa M.; Lieberman, Frank; Robins, H. Ian; Chang, Susan M.; Yung, W. K. Alfred; Drappatz, Jan; Mehta, Minesh P.; Levin, Victor A.; Aldape, Kenneth; Dancey, Janet E.; Wright, John J.; Prados, Michael D.; Cloughesy, Timothy F.; Wen, Patrick Y.; Gilbert, Mark R. Share Save
EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma Wu, Shaofang; Gao, Feng; Zheng, Siyuan; Zhang, Chen; Martinez-Ledesma, Emmanuel; Ezhilarasan, Ravesanker; Ding, Jie; Li, Xiaolong; Feng, Ningping; Multani, Asha; Sulman, Erik P.; Verhaak, Roel G.; de Groot, John F.; Heffernan, Tim P.; Yung, W. K. Alfred; Koul, Dimpy Share Save
A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma Puduvalli, Vinay K.; Wu, Jing; Yuan, Ying; Armstrong, Terri S.; Vera, Elizabeth; Wu, Jimin; Xu, Jihong; Giglio, Pierre; Colman, Howard; Walbert, Tobias; Raizer, Jeffrey; Groves, Morris D.; Tran, David; Iwamoto, Fabio; Avgeropoulos, Nicholas; Paleologos, Nina; Fink, Karen; Peereboom, David; Chamberlain, Marc; Merrell, Ryan; Prado, Marta Penas; Yung, W. K. Alfred; Gilbert, Mark R. Share Save
A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma van den Bent, Martin; Azaro, Analia; De Vos, Filip; Sepulveda, Juan; Yung, W. K. Alfred; Wen, Patrick Y.; Lassman, Andrew B.; Joerger, Markus; Tabatabai, Ghazaleh; Rodon, Jordi; Tiedt, Ralph; Zhao, Sylvia; Kirsilae, Tiina; Cheng, Yi; Vicente, Sergio; Balbin, O. Alejandro; Zhang, Hefei; Wick, Wolfgang Share Save
Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages de Groot, John; Penas-Prado, Marta; Alfaro-Munoz, Kristin; Hunter, Kathy; Pei, Be Lian; O'Brien, Barbara; Weathers, Shiao-Pei; Loghin, Monica; Kamiya Matsouka, Carlos; Yung, W. K. Alfred; Mandel, Jacob; Wu, Jimin; Yuan, Ying; Zhou, Shouhao; Fuller, Gregory N.; Huse, Jason; Rao, Ganesh; Weinberg, Jeffrey S.; Prabhu, Sujit S.; McCutcheon, Ian E.; Lang, Frederick F.; Ferguson, Sherise D.; Sawaya, Raymond; Colen, Rivka; Yadav, Shalini S.; Blando, Jorge; Vence, Luis; Allison, James; Sharma, Padmanee; Heimberger, Amy B. Share Save
Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma Li, Xiaolong; Martinez-Ledesma, Emmanuel; Zhang, Chen; Gao, Feng; Zheng, Siyuan; Ding, Jie; Wu, Shaofang; Nghi Nguyen; Clifford, Stephan C.; Wen, Patrick Y.; Ligon, Keith L.; Yung, W. K. Alfred; Koul, Dimpy Share Save
Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center Harrison, Rebecca A.; Anderson, Mark D.; Cachia, David; Kamiya-Matsuoka, Carlos; Weathers, Shiao-Pei S.; O'Brien, Barbara J.; Penas-Prado, Marta; Yung, W. K. Alfred; Wu, Jimin; Yuan, Ying; de Groot, John F. Share Save
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma Maraka, Stefania; Groves, Morris D.; Mammoser, Aaron G.; Melguizo-Gavilanes, Isaac; Conrad, Charles A.; Tremont-Lukats, Ivo W.; Loghin, Monica E.; Obrien, Barbara J.; Puduvalli, Vinay K.; Sulman, Erik P.; Hess, Kenneth R.; Aldape, Kenneth D.; Gilbert, Mark R.; de Groot, John F.; Yung, W. K. Alfred; Penas-Prado, Marta Share Save
Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE Alexander, Brian M.; Ba, Sujuan; Berger, Mitchel S.; Berry, Donald A.; Cavenee, Webster K.; Chang, Susan M.; Cloughesy, Timothy F.; Jiang, Tao; Khasraw, Mustafa; Li, Wenbin; Mittman, Robert; Poste, George H.; Wen, Patrick Y.; Yung, W. K. Alfred; Barker, Anna D. Share Save
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