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Tumor-Infiltrating Lymphocytes in Necrotic Tumors after Melanoma Neoadjuvant Anti-PD-1 Therapy Correlate with Pathologic Response and Recurrence-Free Survival Ma, Kevin L.; Mitchell, Tara C.; Dougher, Meaghan; Sharon, Cimarron E.; Tortorello, Gabriella N.; Elder, David E.; Morgan, Eric E.; Gimotty, Phyllis A.; Huang, Alexander C.; Amaravadi, Ravi K.; Schuchter, Lynn M.; Flowers, Ahron; Miura, John T.; Karakousis, Giorgos C.; Xu, Xiaowei Share Save
Long-term outcomes to neoadjuvant pembrolizumab based on pathological response for patients with resectable stage III/IV cutaneous melanoma (vol 34, pg 806, 2023) Sharon, C. E.; Tortorello, G. N.; Ma, K. L.; Huang, A. C.; Xu, X.; Giles, L. R.; Mcgettigan, S.; Kreider, K.; Schuchter, L. M.; Mathew, A. J.; Amaravadi, R. K.; Gimotty, P. A.; Miura, J. T.; Karakousis, G. C.; Mitchell, T. C. Share Save
Clinician- and Patient-Directed Communication Strategies for Patients With Cancer at High Mortality Risk A Cluster Randomized Trial Takvorian, Samuel U.; Gabriel, Peter; Wileyto, E. Paul; Blumenthal, Daniel; Tejada, Sharon; Clifton, Alicia B. W.; Asch, David A.; Buttenheim, Alison M.; Rendle, Katharine A.; Shelton, Rachel C.; Chaiyachati, Krisda H.; Fayanju, Oluwadamilola M.; Ware, Susan; Schuchter, Lynn M.; Kumar, Pallavi; Salam, Tasnim; Lieberman, Adina; Ragusano, Daniel; Bauer, Anna-Marika; Scott, Callie A.; Shulman, Lawrence N.; Schnoll, Robert; Beidas, Rinad S.; Bekelman, Justin E.; Parikh, Ravi B. Share Save
FDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma Anderson, Thomas M.; Chang, Bryan H.; Huang, Alexander C.; Xu, Xiaowei; Yoon, Daniel; Shang, Catherine G.; Mick, Rosemarie; Schubert, Erin; McGettigan, Suzanne; Kreider, Kristin; Xu, Wei; Wherry, E. John; Schuchter, Lynn M.; Amaravadi, Ravi K.; Mitchell, Tara C.; Farwell, Michael D. Share Save
Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity Zhong, Wenqun; Lu, Youtao; Han, Xuexiang; Yang, Jingbo; Qin, Zhiyuan; Zhang, Wei; Yu, Ziyan; Wu, Bin; Liu, Shujing; Xu, Wei; Zheng, Cathy; Schuchter, Lynn M.; Karakousis, Giorgos C.; Mitchell, Tara C.; Amaravadi, Ravi; Flowers, Ahron J.; Gimotty, Phyllis A.; Xiao, Min; Mills, Gordon; Herlyn, Meenhard; Dong, Haidong; Mitchell, Michael J.; Kim, Junhyong; Xu, Xiaowei; Guo, Wei Share Save
Long-term outcomes to neoadjuvant pembrolizumab based on pathological response for patients with resectable stage III/IV cutaneous melanoma Sharon, C. E.; Tortorello, G. N.; Ma, K. L.; Huang, A. C.; Xu, X.; Giles, L. R.; Mcgettigan, S.; Kreider, K.; Schuchter, L. M.; Mathew, A. J.; Amaravadi, R. K.; Gimotty, P. A.; Miura, J. T.; Karakousis, G. C.; Mitchell, T. C. Share Save
A Phase II Trial of the CD40 Agonistic Antibody Sotigalimab (APX005M) in Combination with Nivolumab in Subjects with Metastatic Melanoma with Confirmed Disease Progression on Anti-PD-1 Therapy Weiss, Sarah A.; Sznol, Mario; Shaheen, Montaser; Berciano-Guerrero, Miguel-Angel; Couselo, Eva Munoz; Rodriguez-Abreu, Delvys; Boni, Valentina; Schuchter, Lynn M.; Gonzalez-Cao, Maria; Arance, Ana; Wei, Wei; Ganti, Apar Kishor; Hauke, Ralph J.; Berrocal, Alfonso; Iannotti, Nicholas O.; Hsu, Frank J.; Kluger, Harriet M. Share Save
Patient-derived melanoma organoid models facilitate the assessment of immunotherapies Ou, Lingling; Liu, Shujing; Wang, Huaishan; Guo, Yeye; Guan, Lei; Shen, Longbin; Luo, Ruhui; Elder, David E.; Huang, Alexander C.; Karakousis, Giorgos; Miura, John; Mitchell, Tara; Schuchter, Lynn; Amaravadi, Ravi; Flowers, Ahron; Mou, Haiwei; Yi, Fan; Guo, Wei; Ko, Jina; Chen, Qing; Tian, Bin; Herlyn, Meenhard; Xu, Xiaowei Share Save
The FBXO4 Tumor Suppressor Functions as a Barrier to BrafV600E-Dependent Metastatic Melanoma Lee, Eric K.; Lian, Zhaorui; D'Andrea, Kurt; Letrero, Richard; Sheng, Weiqi; Liu, Shujing; Diehl, J. Nathaniel; Pytel, Dariusz; Barbash, Olena; Schuchter, Lynn; Amaravaradi, Ravi; Xu, Xiaowei; Herlyn, Meenhard; Nathanson, Katherine L.; Diehl, J. Alan Share Save
PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine Herati, Ramin Sedaghat; Knorr, David A.; Vella, Laura A.; Silva, Luisa Victoria; Chilukuri, Lakshmi; Apostolidis, Sokratis A.; Huang, Alexander C.; Muselman, Alexander; Manne, Sasikanth; Kuthuru, Oliva; Staupe, Ryan P.; Adamski, Sharon A.; Kannan, Senthil; Kurupati, Raj K.; Ertl, Hildegund C. J.; Wong, Jeffrey L.; Bournazos, Stylianos; McGettigan, Suzanne; Schuchter, Lynn M.; Kotecha, Ritesh R.; Funt, Samuel A.; Voss, Martin H.; Motzer, Robert J.; Lee, Chung-Han; Bajorin, Dean F.; Mitchell, Tara C.; Ravetch, Jeffrey, V; Wherry, E. John Share Save
HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8+ T-cell infiltration into tumors Guan, Lei; Wu, Bin; Li, Ting; Beer, Lynn A.; Sharma, Gaurav; Li, Mingyue; Lee, Chin Nien; Liu, Shujing; Yang, Changsong; Huang, Lili; Frederick, Dennie T.; Boland, Genevieve M.; Shao, Guangcan; Svitkina, Tatyana M.; Cai, Kathy Q.; Chen, Fangping; Dong, Meng-Qiu; Mills, Gordon B.; Schuchter, Lynn M.; Karakousis, Giorgos C.; Mitchell, Tara C.; Flaherty, Keith T.; Speicher, David W.; Chen, Youhai H.; Herlyn, Meenhard; Amaravadi, Ravi K.; Xu, Xiaowei; Guo, Wei Share Save
Preclinical platforms to study therapeutic efficacy of human γδ T cells Ou, Lingling; Wang, Huaishan; Huang, Hui; Zhou, Zhiyan; Lin, Qiang; Guo, Yeye; Mitchell, Tara; Huang, Alexander C.; Karakousis, Giorgos; Schuchter, Lynn; Amaravadi, Ravi; Guo, Wei; Salvino, Joseph; Herlyn, Meenhard; Xu, Xiaowei Share Save
Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers Giles, Josephine R.; Manne, Sasikanth; Freilich, Elizabeth; Oldridge, Derek A.; Baxter, Amy E.; George, Sangeeth; Chen, Zeyu; Huang, Hua; Chilukuri, Lakshmi; Carberry, Mary; Giles, Lydia; Weng, Nan-Ping P.; Young, Regina M.; June, Carl H.; Schuchter, Lynn M.; Amaravadi, Ravi K.; Xu, Xiaowei; Karakousis, Giorgos C.; Mitchell, Tara C.; Huang, Alexander C.; Shi, Junwei; Wherry, E. John Share Save
ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression Zhang, Wei; Zhong, Wenqun; Wang, Beike; Yang, Jiegang; Yang, Jingbo; Yu, Ziyan; Qin, Zhiyuan; Shi, Alex; Xu, Wei; Zheng, Cathy; Schuchter, Lynn M.; Karakousis, Giorgos C.; Mitchell, Tara C.; Amaravadi, Ravi; Herlyn, Meenhard; Dong, Haidong; Gimotty, Phyllis A.; Daaboul, George; Xu, Xiaowei; Guo, Wei Share Save
Automated Text-Based Symptom Monitoring With Rapid Clinician Triage for Patients With Cancer and Suspected or Confirmed COVID-19 Cotner, Cody E.; Balachandran, Mohan; Do, David; Ferrell, Will; Khan, Neda; Kopinsky, Michael; McGettigan, Suzanne; Morgan, Anna U.; Zinck, Lindsey; Schuchter, Lynn M.; Shulman, Lawrence N.; Asch, David A.; Manz, Christopher R.; Parikh, Ravi B. Share Save
PHASE II OF CD40 AGONISTIC ANTIBODY SOTIGALIMAB (APX005M) IN COMBINATION WITH NIVOLUMAB IN SUBJECTS WITH METASTATIC MELANOMA WITH CONFIRMED DISEASE PROGRESSION ON ANTI-PD-1 THERAPY Weiss, Sarah; Sznol, Mario; Shaheen, Montaser; Berciano-Guerrero, Miguel-Angel; Felip, Enriqueta; Rodriguez-Abreu, Delvys; Arance, Ana Maria; Boni, Valentina; Linette, Gerald; Schuchter, Lynn; Gonzalez-Cao, Maria; Iannotti, Nicholas; Ganti, Apar Kishor; Hauke, Ralph; Berrocal, Alfonso; Filbert, Erin; Kluger, Harriet Share Save