Not logged in Base-excision repair pathway shapes 5-methylcytosine deamination signatures in pan-cancer genomes Silveira, Andre Bortolini; Houy, Alexandre; Ganier, Olivier; Ozemek, Beguem; Vanhuele, Sandra; Vincent-Salomon, Anne; Cassoux, Nathalie; Mariani, Pascale; Pierron, Gaelle; Leyvraz, Serge; Rieke, Damian; Picca, Alberto; Bielle, Franck; Yaspo, Marie-Laure Share Save
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer Kendzia, Sandra; Franke, Susanne; Kroehler, Tarek; Golob-Schwarzl, Nicole; Schweiger, Caroline; Toeglhofer, Anna M.; Skofler, Christina; Uranitsch, Stefan; El-Heliebi, Amin; Fuchs, Julia; Punschart, Andreas; Stiegler, Philipp; Keil, Marlen; Hoffmann, Jens; Henderson, David; Lehrach, Hans; Yaspo, Marie-Laure; Reinhard, Christoph; Schaefer, Reinhold; Keilholz, Ulrich; Regenbrecht, Christian; Schicho, Rudolf; Fickert, Peter; Lax, Sigurd F.; Erdmann, Frank; Schulz, Marcel H.; Kiemer, Alexandra K.; Haybaeck, Johannes; Kessler, Sonja M. Share Save
Biomarker-driven therapies for metastatic uveal melanoma: A prospective precision oncology feasibility study Leyvraz, Serge; Konietschke, Frank; Peuker, Caroline; Schuette, Moritz; Kessler, Thomas; Ochsenreither, Sebastian; Ditzhaus, Marc; Spruenken, Erin D.; Doerpholz, Gina; Lamping, Mario; Rieke, Damian T.; Klinghammer, Konrad; Burock, Susen; Ulrich, Claas; Poch, Gabriela; Schaefer, Reinhold; Klauschen, Frederick; Joussen, Antonia; Yaspo, Marie-Laure; Keilholz, Ulrich Share Save
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Endocytosis-Mediated Replenishment of Amino Acids Favors Cancer Cell Proliferation and Survival in Chromophobe Renal Cell Carcinoma Xiao, Yi; Rabien, Anja; Buschow, Rene; Amtislavskiy, Vyacheslav; Busch, Jonas; Kilic, Ergin; Villegas, Sonia L.; Timmermann, Bernd; Schuette, Moritz; Mielke, Thorsten; Yaspo, Marie-Laure; Jung, Klaus; Meierhofer, David Share Save
Rational therapy with vigabatrin and a ketogenic diet in a patient with GAD1 deficiency von Hardenberg, Sandra; Richter, Manuela F.; Hethey, Sven; Yaspo, Marie-Laure; Auber, Bernd; Schlegelberger, Brigitte; Illig, Thomas; Guthmann, Florian; Christen, Hans-Juergen; Ripperger, Tim; Bergmann, Anke K. Share Save
Support of a molecular tumour board by an evidence-based decision management system for precision oncology Lamping, Mario; Benary, Manuela; Leyvraz, Serge; Messerschmidt, Clemens; Blanc, Eric; Kessler, Thomas; Schuette, Moritz; Lenze, Dido; Joehrens, Korinna; Burock, Susen; Klinghammer, Konrad; Ochsenreither, Sebastian; Sers, Christine; Schaefer, Reinhold; Tinhofer, Ingeborg; Beule, Dieter; Klauschen, Frederick; Yaspo, Marie-Laure; Keilholz, Ulrich; Rieke, Damian T. Share Save
5-Fluorouracil treatment induces characteristic T>G mutations in human cancer Christenser, Sharon; Van Der Roest, Bastiaan; Besselink, Nicolle; Janssen, Roel; Boymans, Sander; Martens, John W. M.; Yaspo, Marie-Laure; Priestley, Peter; Kuijk, Ewart; Cuppen, Edwin; Van Hoeck, Arne Share Save
The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia Beekman, Renee; Chapaprieta, Vicente; Russinol, Nuria; Vilarrasa-Blasi, Roser; Verdaguer-Dot, Nuria; Martens, Joost H. A.; Duran-Ferrer, Marti; Kulis, Marta; Serra, Francois; Javierre, Biola M.; Wingett, Steven W.; Clot, Guillem; Queiros, Ana C.; Castellano, Giancarlo; Blanc, Julie; Gut, Marta; Merkel, Angelika; Heath, Simon; Vlasova, Anna; Ullrich, Sebastian; Palumbo, Emilio; Enjuanes, Anna; Martin-Garcia, David; Bea, Silvia; Pinyol, Magda; Aymerich, Marta; Royo, Romina; Puiggros, Montserrat; Torrents, David; Datta, Avik; Lowy, Ernesto; Kostadima, Myrto; Roller, Masa; Clarke, Laura; Flicek, Paul; Agirre, Xabier; Prosper, Felipe; Baumann, Tycho; Delgado, Julio; Lopez-Guillermo, Armando; Fraser, Peter; Yaspo, Marie-Laure; Guigo, Roderic; Siebert, Reiner; Marti-Renom, Marc A.; Puente, Xose S.; Lopez-Otin, Carlos; Gut, Ivo; Stunnenberg, Hendrik G.; Campo, Elias; Martin-Subero, Jose I. Share Save
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Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors Schuette, Moritz; Risch, Thomas; Abdavi-Azar, Nilofar; Boehnke, Karsten; Schumacher, Dirk; Keil, Marlen; Yildirimman, Reha; Jandrasits, Christine; Borodina, Tatiana; Amstislavskiy, Vyacheslav; Worth, Catherine L.; Schweiger, Caroline; Liebs, Sandra; Lange, Martin; Warnatz, Hans-Joerg; Butcher, Lee M.; Barrett, James E.; Sultan, Marc; Wierling, Christoph; Golob-Schwarzl, Nicole; Lax, Sigurd; Uranitsch, Stefan; Becker, Michael; Welte, Yvonne; Regan, Joseph Lewis; Silvestrov, Maxine; Kehler, Inge; Fusi, Alberto; Kessler, Thomas; Herwig, Ralf; Landegren, Ulf; Wienke, Dirk; Nilsson, Mats; Velasco, Juan A.; Garin-Chesa, Pilar; Reinhard, Christoph; Beck, Stephan; Schaefer, Reinhold; Regenbrecht, Christian R. A.; Henderson, David; Lange, Bodo; Haybaeck, Johannes; Keilholz, Ulrich; Hoffmann, Jens; Lehrach, Hans; Yaspo, Marie-Laure Share Save
Impaired Planar Germ Cell Division in the Testis, Caused by Dissociation of RHAMM from the Spindle, Results in Hypofertility and Seminoma Li, Huaibiao; Frappart, Lucien; Moll, Juergen; Winkler, Anne; Kroll, Torsten; Hamann, Jana; Kufferath, Iris; Groth, Marco; Taudien, Stefan; Schuette, Moritz; Yaspo, Marie-Laure; Heuer, Heike; Lange, Bodo M. H.; Platzer, Matthias; Zatloukal, Kurt; Herrlich, Peter; Ploubidou, Aspasia Share Save
Genomics and drug profiling of fatal TCF3-HLF-positive acute lymphoblastic leukemia identifies recurrent mutation patterns and therapeutic options Fischer, Ute; Forster, Michael; Rinaldi, Anna; Risch, Thomas; Sungalee, Stephanie; Warnatz, Hans-Joerg; Bornhauser, Beat; Gombert, Michael; Kratsch, Christina; Stuetz, Adrian M.; Sultan, Marc; Tchinda, Joelle; Worth, Catherine L.; Amstislavskiy, Vyacheslav; Badarinarayan, Nandini; Baruchel, Andre; Bartram, Thies; Basso, Giuseppe; Canpolat, Cengiz; Cario, Gunnar; Cave, Helene; Dakaj, Dardane; Delorenzi, Mauro; Dobay, Maria Pamela; Eckert, Cornelia; Ellinghaus, Eva; Eugster, Sabrina; Frismantas, Viktoras; Ginzel, Sebastian; Haas, Oskar A.; Heidenreich, Olaf; Hemmrich-Stanisak, Georg; Hezaveh, Kebria; Hoell, Jessica I.; Hornhardt, Sabine; Husemann, Peter; Kachroo, Priyadarshini; Kratz, Christian P.; te Kronnie, Geertruy; Marovca, Blerim; Niggli, Felix; McHardy, Alice C.; Moorman, Anthony V.; Panzer-Gruemayer, Renate; Petersen, Britt S.; Raeder, Benjamin; Ralser, Meryem; Rosenstiel, Philip; Schaefer, Daniel; Schrappe, Martin; Schreiber, Stefan; Schuette, Moritz; Stade, Bjoern; Thiele, Ralf; von der Weid, Nicolas; Vora, Ajay; Zaliova, Marketa; Zhang, Langhui; Zichner, Thomas; Zimmermann, Martin; Lehrach, Hans; Borkhardt, Arndt; Bourquin, Jean-Pierre; Franke, Andre; Korbel, Jan O.; Stanulla, Martin; Yaspo, Marie-Laure Share Save
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Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome Groet, J; Ives, JH; South, AP; Baptista, PR; Jones, TA; Yaspo, ML; Lehrach, H; Potier, MC; Van Broeckhoven, C; Nizetic, D Share Save
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