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J

Joseph R. Bertino

university of michigan system

84H-index
677Paper Count
2.9WCitation Count
Published Papers 49
Publication Date
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In cancer, all roads lead to NADPH
errPHARMACOLOGY & THERAPEUTICS
IF12.5
err2021-10-01
err47
PREAI
errRather, Gulam Mohmad; Pramono, Alvinsyah Adhityo; Szekely, Zoltan; Bertino, Joseph R.; Tedeschi, Philip Michael
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An antibody drug conjugate targeting activated matriptase, exhibits synergistic cytotoxicity with a PARP inhibitor, olaparib in triple negative breast cancer
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errRather, Gulam M.; Szekely, Zoltan; Bertino, Joseph R.
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errSave
Rapid Assessment of Surface Markers on Cancer Cells Using Immuno-Magnetic Separation and Multi-frequency Impedance Cytometry for Targeted Therapy
errSCIENTIFIC REPORTS
IF3.9
err2020-02-20
err34
errOAAI
errLin, Zhongtian; Lin, Siang-Yo; Xie, Pengfei; Lin, Chen-Yong; Rather, Gulam M.; Bertino, Joseph R.; Javanmard, Mehdi
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Toward point-of-care assessment of patient response: a portable tool for rapidly assessing cancer drug efficacy using multifrequency impedance cytometry and supervised machine learning
errMICROSYSTEMS & NANOENGINEERING
IF9.9
err2019-07-15
err57
errOAAI
errAhuja, Karan; Rather, Gulam M.; Lin, Zhongtian; Sui, Jianye; Xie, Pengfei; Le, Tuan; Bertino, Joseph R.; Javanmard, Mehdi
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errSave
A modified L-penetratin peptide targeting e2f-1, 2 and 3 is effective in combination with cisplatin or pemetrexed against prostate and lung cancer cell lines
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errRather, Gulam M.; Anyanwu, Michael; Kerrigan, John E.; Scotto, Kathleen W.; Garbuzenko, Olga; Minko, Tamara; Szekely, Zoltan; Bertino, Joseph R.
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Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2019-05-22
err53
errOAAI
errStein, Mark N.; Malhotra, Jyoti; Tarapore, Rohinton S.; Malhotra, Usha; Silk, Ann W.; Chan, Nancy; Rodriguez, Lorna; Aisner, Joseph; Aiken, Robert D.; Mayer, Tina; Haffty, Bruce G.; Newman, Jenna H.; Aspromonte, Salvatore M.; Bommareddy, Praveen K.; Estupinian, Ricardo; Chesson, Charles B.; Sadimin, Evita T.; Li, Shengguo; Medina, Daniel J.; Saunders, Tracie; Frankel, Melissa; Kareddula, Aparna; Damare, Sherrie; Wesolowsky, Elayne; Gabel, Christian; El-Deiry, Wafik S.; Prabhu, Varun V.; Allen, Joshua E.; Stogniew, Martin; Oster, Wolfgang; Bertino, Joseph R.; Libutti, Steven K.; Mehnert, Janice M.; Zloza, Andrew
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errSave
A Novel Antibody-Toxin Conjugate to Treat Mantle Cell Lymphoma
errFRONTIERS IN ONCOLOGY
IF3.3
err2019-04-10
err3
errOAAI
errRather, Gulam M.; Lin, Siang-Yo; Lin, Hongxia; Szekely, Zoltan; Bertino, Joseph R.
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Exploiting methionine restriction for cancer treatment
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2018-08-01
err70
PREAI
errChaturvedi, Sushma; Hoffman, Robert M.; Bertino, Joseph R.
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errSave
Enhancement of the anticancer activity of methylenetetrahydrofolate dehydrogenase knockdown by folate depletion with carboxypeptidase G2
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errRather, Gulam M.; Kerrigan, John E.; Scotto, Kathleen W.; Bertino, Joseph R.
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errSave
Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2017-12-03
err51
errOAAI
errMorgan, Katherine M.; Fischer, Bruce S.; Lee, Francis Y.; Shah, Jamie J.; Bertino, Joseph R.; Rosenfeld, Jeffrey; Singh, Amartya; Khiabanian, Hossein; Pine, Sharon R.
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errSave
First-in-Human Clinical Trial of Oral ONC201 in Patients with Refractory Solid Tumors
errCLINICAL CANCER RESEARCH
IF10.2
err2017-08-01
err125
errOAAI
errStein, Mark N.; Bertino, Joseph R.; Kaufman, Howard L.; Mayer, Tina; Moss, Rebecca; Silk, Ann; Chan, Nancy; Malhotra, Jyoti; Rodriguez, Lorna; Aisner, Joseph; Aiken, Robert D.; Haffty, Bruce G.; DiPaola, Robert S.; Saunders, Tracie; Zloza, Andrew; Damare, Sherri; Beckett, Yasmeen; Yu, Bangning; Najmi, Saltanat; Gabel, Christian; Dickerson, Siobhan; Zheng, Ling; El-Deiry, Wafik S.; Allen, Joshua E.; Stogniew, Martin; Oster, Wolfgang; Mehnert, Janice M.
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errSave
Development of an antibody-drug conjugate with broad anticancer activity
errCANCER RESEARCH
IF16.6
err2017-07-01
err0
PREAI
errLin, Siang-Yo; Szekely, Zoltan; Lin, Chen-Yong; Bertino, Joseph R.; Rather, Gulam Mohmad
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errSave
Molecular imaging reveals skeletal engraftment sites of transplanted bone marrow cells
errCELL TRANSPLANTATION
IF3.2
err2017-06-22
err19
PREAI
errMayer-Kuckuk, Philipp; Doubrovin, Mikhail; Bidaut, Luc; Budak-Alpdogan, Tulin; Cai, Shangde; Hubbard, Vanessa; Alpdogan, Onder; van den Brink, Marcel; Bertino, Joseph R.; Blasberg, Ronald G.; Banerjee, Debabrata; Gelovani, Juri
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errSave
Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity
errSCIENTIFIC REPORTS
IF3.9
err2017-03-08
err44
errOAAI
errKimani, Stanley G.; Kumar, Sushil; Bansal, Nitu; Singh, Kamalendra; Kholodovych, Vladyslav; Comollo, Thomas; Peng, Youyi; Kotenko, Sergei V.; Sarafianos, Stefan G.; Bertino, Joseph R.; Welsh, William J.; Birge, Raymond B.
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errSave
NAD+ Kinase as a Therapeutic Target in Cancer
errCLINICAL CANCER RESEARCH
IF10.2
err2016-10-31
err67
errOAAI
errTedeschi, Philip M.; Bansal, Nitu; Kerrigan, John E.; Abali, Emine E.; Scotto, Kathleen W.; Bertino, Joseph R.
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errSave
D2-like dopamine receptor antagonism by ONC201 identified by confluence of computational, receptor binding, and clinical studies
errCANCER RESEARCH
IF16.6
err2016-07-15
err3
PREAI
errMadhukar, Neel S.; Elemento, Olivier; Benes, Cyril H.; Garnett, Mathew J.; Stein, Mark; Bertino, Joseph R.; Kaufman, Howard L.; Arrillaga-Romany, Isabel; Batchelor, Tracy T.; Schalop, Lee; Oster, Wolfgang; Stogniew, Martin; Andreeff, Michael; Ei-Deiry, Wafik S.; Allen, Joshua E.
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errSave
Functional annotation of rare gene aberration drivers of pancreatic cancer
errNATURE COMMUNICATIONS
IF15.7
err2016-01-25
err59
errOAAI
errTsang, Yiu Huen; Dogruluk, Turgut; Tedeschi, Philip M.; Wardwell-Ozgo, Joanna; Lu, Hengyu; Espitia, Maribel; Nair, Nikitha; Minelli, Rosalba; Chong, Zechen; Chen, Fengju; Chang, Qing Edward; Dennison, Jennifer B.; Dogruluk, Armel; Li, Min; Ying, Haoqiang; Bertino, Joseph R.; Gingras, Marie-Claude; Ittmann, Michael; Kerrigan, John; Chen, Ken; Creighton, Chad J.; Eterovic, Karina; Mills, Gordon B.; Scott, Kenneth L.
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Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development
errMOLECULAR CANCER RESEARCH
IF4.7
err2015-10-18
err73
errOAAI
errTedeschi, Philip M.; Vazquez, Alexei; Kerrigan, John E.; Bertino, Joseph R.
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errSave
Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy
errMOLECULAR PHARMACOLOGY
IF3
err2015-10-01
err38
errOAAI
errTedeschi, Philip M.; Lin, HongXia; Gounder, Murugesan; Kerrigan, John E.; Abali, Emine Ercikan; Scotto, Kathleen; Bertino, Joseph R.
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errSave
Synergistic anti-tumor activity of the Notch gamma secretase inhibitor BMS-906024 and paclitaxel in the treatment of lung adenocarcinoma
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errMorgan, Katherine M.; Lee, Francis; Michaud, Erin; Bertino, Joseph R.; Fischer, Bruce S.; Pine, Sharon R.
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
G
Gordon B. Mills
H-index: 231 · Papers: 3.5K
M
Marco A. Marra
H-index: 190 · Papers: 1.3K
M
Mark A. Rubin
H-index: 186 · Papers: 1.5K
M
Michael Andreeff
H-index: 139 · Papers: 2.0K
C
Chad J. Creighton
H-index: 128 · Papers: 1.1K
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