Not logged inFunctional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation
Sun, Yuting; Bandi, Madhavi; Lofton, Timothy; Smith, Melinda; Bristow, Christopher A.; Carugo, Alessandro; Rogers, Norma; Leonard, Paul; Chang, Qing; Mullinax, Robert; Han, Jing; Shi, Xi; Seth, Sahil; Meyers, Brooke A.; Miller, Meredith; Miao, Lili; Ma, Xiaoyan; Feng, Ningping; Giuliani, Virginia; Do, Mary Geck; Czako, Barbara; Palmer, Wylie S.; Mseeh, Faika; Asara, John M.; Jiang, Yongying; Morlacchi, Pietro; Zhao, Shuping; Peoples, Michael; Tieu, Trang N.; Warmoes, Marc O.; Lorenzi, Philip L.; Muller, Florian L.; DePinho, Ronald A.; Draetta, Giulio F.; Toniatti, Carlo; Jones, Philip; Heffernan, Timothy P.; Marszalek, Joseph R. .png)
Share.png)
SaveThe RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A ExpressionHuang, Lu; Malu, Shruti; McKenzie, Jodi A.; Andrews, Miles C.; Talukder, Amjad H.; Trang Tieu; Karpinets, Tatiana; Haymaker, Cara; Forget, Marie-Andree; Williams, Leila J.; Wang, Zhe; Mbofung, Rina M.; Wang, Zhi-Qiang; Davis, Richard Eric; Lo, Roger S.; Wargo, Jennifer A.; Davies, Michael A.; Bernatchez, Chantale; Heffernan, Timothy; Amaria, Rodabe N.; Korkut, Anil; Peng, Weiyi; Roszik, Jason; Lizee, Gregory; Woodman, Scott E.; Hwu, Patrick Share Save The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer ImmunotherapyMcKenzie, Jodi A.; Mbofung, Rina M.; Malu, Shruti; Zhang, Min; Ashkin, Emily; Devi, Seram; Williams, Leila; Trang Tieu; Peng, Weiyi; Pradeep, Sunila; Xu, Chunyu; Manrique, Soraya Zorro; Liu, Chengwen; Huang, Lu; Chen, Yuan; Forget, Marie-Andree; Haymaker, Cara; Bernatchez, Chantale; Satani, Nikunj; Muller, Florian; Hwu, Patrick Share Save HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genesMbofung, Rina M.; McKenzie, Jodi A.; Malu, Shruti; Zhang, Min; Peng, Weiyi; Liu, Chengwen; Kuiatse, Isere; Tieu, Trang; Williams, Leila; Devi, Seram; Ashkin, Emily; Xu, Chunyu; Huang, Lu; Zhang, Minying; Talukder, Amjad H.; Tripathi, Satyendra C.; Khong, Hiep; Satani, Nikunj; Muller, Florian L.; Roszik, Jason; Heffernan, Timothy; Allison, James P.; Lizee, Gregory; Hanash, Sam M.; Proia, David; Amaria, Rodabe; Davis, R. Eric; Hwu, Patrick Share Save Share Save Loss of PTEN promotes resistance to T cell-mediated immunotherapyPeng, Weiyi; Chen, Jie Qing; Liu, Chengwen; Malu, Shruti; Creasy, Caitlin; Tetzlaff, Michael; Xu, Chunyu; McKenzie, Jodi; Zhang, Chunlei; Liang, Xiaoxuan; Williams, Leila; Deng, Wanleng; Chen, Guo; Mbofung, Rina; Lazar, Alexander; Torres-Cabala, Carlos; Cooper, Zachary; Chen, Pei-Ling; Tieu, Trang; Spranger, Stefani; Yu, Xiaoxing; Bernatchez, Chantale; Forget, Marie-Andree; Haymaker, Cara; Amaria, Rodabe; McQuade, Jennifer; Glitza, Isabella; Cascone, Tina; Li, Haiyan; Kwong, Lawrence; Heffernan, Timothy; Hu, Jianhua; Bassett, Roland; Bosenberg, Marcus; Woodman, Scott; Overwijk, Willem; Lizee, Gregory; Roszik, Jason; Gajewski, Thomas; Wargo, Jennifer; Gershenwald, Jeffrey; Radvanyi, Laszlo; Davies, Michael; Hwu, Patrick Share Save Inhibition of HSP90 enhances T cell-mediated antitumor immune responses through expression of interferon-alpha response GenesMbofung, Rina M.; McKenzie, Jodi A.; Malu, Shruti; Liu, Chengwen; Williams, Leila; Peng, Weiyi; Wang, Zhe; Tripathi, Satyendra; Tieu, Trang; Zhao, Shuping; Devi, Seram; Kuiatse, Isere; Ashkin, Emily; Bailey, Leah; Roszik, Jason; Hanash, Samir; Heffernan, Timothy; Davis, Richard E.; Amaria, Rodabe N.; Hwu, Patrick Share Save Loss of PTEN Promotes Resistance to T Cell-Mediated ImmunotherapyPeng, Weiyi; Chen, Jie Qing; Liu, Chengwen; Malu, Shruti; Creasy, Caitlin; Tetzlaff, Michael T.; Xu, Chunyu; McKenzie, Jodi A.; Zhang, Chunlei; Liang, Xiaoxuan; Williams, Leila J.; Deng, Wanleng; Chen, Guo; Mbofung, Rina; Lazar, Alexander J.; Torres-Cabala, Carlos A.; Cooper, Zachary A.; Chen, Pei-Ling; Tieu, Trang N.; Spranger, Stefani; Yu, Xiaoxing; Bernatchez, Chantale; Forget, Marie-Andree; Haymaker, Cara; Amaria, Rodabe; McQuade, Jennifer L.; Glitza, Isabella C.; Cascone, Tina; Li, Haiyan S.; Kwong, Lawrence N.; Heffernan, Timothy P.; Hu, Jianhua; Bassett, Roland L.; Bosenberg, Marcus W.; Woodman, Scott E.; Overwijk, Willem W.; Lizee, Gregory; Roszik, Jason; Gajewski, Thomas F.; Wargo, Jennifer A.; Gershenwald, Jeffrey E.; Radvanyi, Laszlo; Davies, Michael A.; Hwu, Patrick Share Save Targeting YAP-Dependent MDSC Infiltration Impairs Tumor ProgressionWang, Guocan; Lu, Xin; Dey, Prasenjit; Deng, Pingna; Wu, Chia Chin; Jiang, Shan; Fang, Zhuangna; Zhao, Kuo; Konaparthi, Ramakrishna; Hua, Sujun; Zhang, Jianhua; Li-Ning-Tapia, Elsa M.; Kapoor, Avnish; Wu, Chang-Jiun; Patel, Neelay Bhaskar; Guo, Zhenglin; Ramamoorthy, Vandhana; Tieu, Trang N.; Heffernan, Tim; Zhao, Di; Shang, Xiaoying; Khadka, Sunada; Hou, Pingping; Hu, Baoli; Jin, Eun-Jung; Yao, Wantong; Pan, Xiaolu; Ding, Zhihu; Shi, Yanxia; Li, Liren; Chang, Qing; Troncoso, Patricia; Logethetis, Christopher J.; McArthur, Mark J.; Chin, Lynda; Wang, Y. Alan; DePinho, Ronaldo A. Share Save Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discoveryZhan, Yanai; Kost-Alimova, Maria; Shi, Xi; Leo, Elisabetta; Bardenhagen, Jennifer P.; Shepard, Hannah E.; Appikonda, Srikanth; Vangamudi, Bhavatarini; Zhao, Shuping; Tieu, Trang N.; Jiang, Shiming; Heffernan, Timothy P.; Marszalek, Joseph R.; Toniatti, Carlo; Draetta, Giulio; Tyler, Jessica; Barton, Michelle; Jones, Philip; Palmer, Wylie S.; Do, Mary K. Geck; Andersen, Jannik N. Share Save The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNFMutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor StudiesVangamudi, Bhavatarini; Paul, Thomas A.; Shah, Parantu K.; Kost-Alimova, Maria; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Heffernan, Timothy P.; Marszalek, Joseph R.; Toniatti, Carlo; Petrocchi, Alessia; Verhelle, Dominique; Owen, Dafydd R.; Draetta, Giulio; Jones, Philip; Palmer, Wylie S.; Sharma, Shikhar; Andersen, Jannik N. Share Save The SMARCA2/4 catalytic activity, but not the bromodomain, is a drug target in SWI/SNF mutant cancersVangamudi, Bhavatarini; Paui, Thomas; Shah, Parantu K.; Alimova, Maria K.; Nottebaum, Lisa; Shi, Xi; Zhan, Yanai; Leo, Elisabetta; Mahadeshwar, Harshad S.; Protopopov, Alexei; Futreal, Andrew; Tieu, Trang N.; Peoples, Mike; Petrocchi, Alessia; Marszalek, Joseph R.; Toniatti, Carlo; Heffernan, Timothy P.; Verhelle, Dominique; Draetta, Giulio; Owen, Dafydd; Jones, Philip; Palmer, Wylie; Sharma, Shikhar; Andersen, Jannik N. Share Save Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain InhibitorPalmer, Wylie S.; Poncet-Montange, Guillaume; Liu, Gang; Petrocchi, Alessia; Reyna, Naphtali; Subramanian, Govindan; Theroff, Jay; Yau, Anne; Kost-Alimova, Maria; Bardenhagen, Jennifer P.; Leo, Elisabetta; Shepard, Hannah E.; Tieu, Trang N.; Shi, Xi; Zhao, Yanai; Zhao, Shuping; Barton, Michelle C.; Draetta, Giulio; Toniatti, Carlo; Jones, Philip; Do, Mary Geck; Andersen, Jannik N. Share Save 
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}