Not logged in Loss of FBXO11 establishes a stem cell program in acute myeloid leukemia by dysregulating LONP1 Kincross, Hayle; Mo, Ya-Chi Angela; Wang, Xuan; Chang, Linda; Duns, Gerben; Mey, Franziska; Jiang, Jihong; Zhu, Zurui; Isak, Naomi; Kwan, Harwood; Lau, Tammy T. Y.; Docking, T. Roderick; Garg, Pranav; Tran, Jessica; Colborne, Shane; Cheng, Se-Wing Grace; Huang, Shujun; Gharaee, Nadia; Willie, Elijah; Parker, Jeremy D. K.; Bridgers, Joshua; Wood, Davis; Geltink, Ramon I. Klein; Morin, Gregg B.; Karsan, Aly Share Save
ASPSCR1-TFE3 reprograms transcription by organizing enhancer loops around hexameric VCP/p97 Pozner, Amir; Li, Li; Verma, Shiv Prakash; Wang, Shuxin; Barrott, Jared J.; Nelson, Mary L.; Yu, Jamie S. E.; Negri, Gian Luca; Colborne, Shane; Hughes, Christopher S.; Zhu, Ju-Fen; Lambert, Sydney L.; Carroll, Lara S.; Smith-Fry, Kyllie; Stewart, Michael G.; Kannan, Sarmishta; Jensen, Bodrie; John, Cini M.; Sikdar, Saif; Liu, Hongrui; Dang, Ngoc Ha; Bourdage, Jennifer; Li, Jinxiu; Vahrenkamp, Jeffery M.; Mortenson, Katelyn L.; Groundland, John S.; Wustrack, Rosanna; Senger, Donna L.; Zemp, Franz J.; Mahoney, Douglas J.; Gertz, Jason; Zhang, Xiaoyang; Lazar, Alexander J.; Hirst, Martin; Morin, Gregg B.; Nielsen, Torsten O.; Shen, Peter S.; Jones, Kevin B. Share Save
The proteome of clear cell ovarian carcinoma Ji, Jennifer X.; Cochrane, Dawn R.; Negri, Gian Luca; Colborne, Shane; Miko, Sandra E. Spencer; Hoang, Lynn N.; Farnell, David; Tessier-Cloutier, Basile; Huvila, Jutta; Thompson, Emily; Leung, Samuel; Chiu, Derek; Chow, Christine; Ta, Monica; Kobel, Martin; Feil, Lucas; Anglesio, Michael; Goode, Ellen L.; Bolton, Kelly; Morin, Gregg B.; Huntsman, David G. Share Save
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations Xu, Jing; Yang, Kevin C.; Go, Nancy Erro; Colborne, Shane; Ho, Cally J.; Hosseini-Beheshti, Elham; Lystad, Alf H.; Simonsen, Anne; Guns, Emma Tomlinson; Morin, Gregg B.; Gorski, Sharon M. Share Save
Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes Asleh, Karama; Negri, Gian Luca; Miko, Sandra E. Spencer; Colborne, Shane; Hughes, Christopher S.; Wang, Xiu Q.; Gao, Dongxia; Gilks, C. Blake; Chia, Stephen K. L.; Nielsen, Torsten O.; Morin, Gregg B. Share Save
Proteotranscriptomic classification and characterization of pancreatic neuroendocrine neoplasms Yang, Kevin C.; Kalloger, Steve E.; Aird, John J.; Lee, Michael K. C.; Rushton, Christopher; Mungall, Karen L.; Mungall, Andrew J.; Gao, Dongxia; Chow, Christine; Xu, Jing; Karasinska, Joanna M.; Colborne, Shane; Jones, Steven J. M.; Schrader, Joerg; Morin, Ryan D.; Loree, Jonathan M.; Marra, Marco A.; Renouf, Daniel J.; Morin, Gregg B.; Schaeffer, David F.; Gorski, Sharon M. Share Save
De novo and cell line models of human mammary cell transformation reveal an essential role for Yb-1 in multiple stages of human breast cancer Lefort, Sylvain; El-Naggar, Amal; Tan, Susanna; Colborne, Shane; Negri, Gian Luca; Pellacani, Davide; Hirst, Martin; Gusterson, Barry; Morin, Gregg B.; Sorensen, Poul H.; Eaves, Connie J. Share Save
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma Zhang, Hai-Feng; Hughes, Christopher S.; Li, Wei; He, Jian-Zhong; Surdez, Didier; El-Naggar, Amal M.; Cheng, Hongwei; Prudova, Anna; Delaidelli, Alberto; Negri, Gian Luca; Li, Xiaojun; Orum-Madsen, Maj Sofie; Lizardo, Michael M.; Oo, Htoo Zarni; Colborne, Shane; Shyp, Taras; Scopim-Ribeiro, Renata; Hammond, Colin A.; Dhez, Anne-Chloe; Langman, Sofya; Lim, Jonathan K. M.; Kung, Sonia H. Y.; Li, Amy; Steino, Anne; Daugaard, Mads; Parker, Seth J.; Geltink, Ramon I. Klein; Orentas, Rimas J.; Xu, Li-Yan; Morin, Gregg B.; Delattre, Olivier; Dimitrov, Dimiter S.; Sorensen, Poul H. Share Save
Multiomics Characterization of Low-Grade Serous Ovarian Carcinoma Identifies Potential Biomarkers of MEK Inhibitor Sensitivity and Therapeutic Vulnerability Shrestha, Raunak; Fernandez, Marta Llaurado; Dawson, Amy; Hoenisch, Joshua; Volik, Stanislav; Lin, Yen-Yi; Anderson, Shawn; Kim, Hannah; Haegert, Anne M.; Colborne, Shane; Wong, Nelson K. Y.; McConeghy, Brian; Bell, Robert H.; Brahmbhatt, Sonal; Lee, Cheng-Han; DiMattia, Gabriel E.; Le Bihan, Stephane; Morin, Gregg B.; Collins, Colin C.; Carey, Mark S. Share Save
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism Orlando, Krystal Ann; Douglas, Amber K.; Abudu, Aierken; Wang, Yemin; Tessier-Cloutier, Basile; Su, Weiping; Peters, Alec; Sherman, Larry S.; Moore, Rayvon; Vinh Nguyen; Negri, Gian Luca; Colborne, Shane; Morin, Gregg B.; Kommoss, Friedrich; Lang, Jessica D.; Hendricks, William P. D.; Raupach, Elizabeth A.; Pirrotte, Patrick; Huntsman, David G.; Trent, Jeffrey M.; Parker, Joel S.; Raab, Jesse R.; Weissman, Bernard E. Share Save
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type Ji, Jennifer X.; Cochrane, Dawn R.; Tessier-Cloutier, Basile; Chen, Shary Yutin; Ho, Germain; Pathak, Khyatiben V.; Alcazar, Isabel N.; Farnell, David; Leung, Samuel; Cheng, Angela; Chow, Christine; Colborne, Shane; Negri, Gian Luca; Kommoss, Friedrich; Karnezis, Anthony; Morin, Gregg B.; McAlpine, Jessica N.; Gilks, C. Blake; Weissman, Bernard E.; Trent, Jeffrey M.; Hoang, Lynn; Pirrotte, Patrick; Wang, Yemin; Huntsman, David G. Share Save
Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis El-Naggar, Amal M.; Somasekharan, Syam Prakash; Wang, Yemin; Cheng, Hongwei; Negri, Gian Luca; Pan, Melvin; Wang, Xue Qi; Delaidelli, Alberto; Rafn, Bo; Cran, Jordan; Zhang, Fan; Zhang, Haifeng; Colborne, Shane; Gleave, Martin; Mandinova, Anna; Kedersha, Nancy; Hughes, Christopher S.; Surdez, Didier; Delattre, Olivier; Wang, Yuzhuo; Huntsman, David G.; Morin, Gregg B.; Sorensen, Poul H. Share Save
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Histone Deacetylase Inhibitors Synergize with Catalytic Inhibitors of EZH2 to Exhibit Antitumor Activity in Small Cell Carcinoma of the Ovary, Hypercalcemic Type Wang, Yemin; Chen, Shary Yuting; Colborne, Shane; Lambert, Galen; Shin, Chae Young; Dos Santos, Nancy; Orlando, Krystal A.; Lang, Jessica D.; Hendricks, William P. D.; Bally, Marcel B.; Karnezis, Anthony N.; Hass, Ralf; Underhill, T. Michael; Morin, Gregg B.; Trent, Jeffrey M.; Weissman, Bernard E.; Huntsman, David G. Share Save
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Targeting the epigenome of small cell hypercalcemic carcinoma of the ovary, hypercalcemic type (SCCOHT) Wang, Yemin; Chen, Shary Yu-ting; Colborne, Shane; Orlando, Krystal; Lang, Jessica; Karnezis, Anthony; Hendricks, William; Morin, Gregg; Weissman, Bernard; Trent, Jeffrey; Huntsman, David Share Save
The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type Wang, Yemin; Chen, Shary Yuting; Karnezis, Anthony N.; Colborne, Shane; Dos Santos, Nancy; Lang, Jessica D.; Hendricks, William P. D.; Orlando, Krystal A.; Yap, Damian; Kommoss, Friedrich; Bally, Marcel B.; Morin, Gregg B.; Trent, Jeffrey M.; Weissman, Bernard E.; Huntsman, David G. Share Save
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