Claudia T. Flynn - Publications, H-index & Citations

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Claudia T. Flynn

Scripps Research Institute

24H-index

83Paper Count

2.0KCitation Count

Published Papers 30

Publication Date

Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates

Science Immunology

IF16.3

2025-10-17

PREAI

Henry J. Sutton; Krystal M. Ma; Jon M. Steichen; Torben Schiffner; Tasha K. Altheide; Alessia Liguori; Danny Lu; Michael Kubitz; Erik Georgeson; Nicole Phelps; Ryan Tingle; Nushin B. Alavi; Elana Ben-Akiva; Xiaoya Zhou; Carolyne Kifude; Claudia T. Flynn; Eva Rakasz; Darrell J. Irvine; William R. Schief; Shane Crotty

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Simultaneous priming of HIV broadly neutralizing antibody precursors to multiple epitopes by germline-targeting mRNA-LNP immunogens in mouse models

Science Immunology

IF16.3

2025-10-17

PREAI

Zhenfei Xie; Xuesong Wang; Yu Yan; Jon M. Steichen; Krystal M. Ma; Christopher A. Cottrell; Eleonora Melzi; Maria Bottermann; Paula Maldonado Villavicencio; Kimmo Rantalainen; Torben Schiffner; John E. Warner; Stephanie R. Weldon; Thavaleak Prum; Jordan R. Ellis-Pugh; Jonathan L. Torres; Abigail M. Jackson; Claudia T. Flynn; Gabriel Ozorowski; Sunny Himansu; Andrea Carfi; Andrew B. Ward; Usha Nair; William R. Schief; Facundo D. Batista

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Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models

Science Translational Medicine

IF14.6

2025-07-30

OAAI

Parham Ramezani-Rad; Christopher A. Cottrell; Ester Marina-Zárate; Alessia Liguori; Elise Landais; Jonathan L. Torres; Amber Myers; Jeong Hyun Lee; Sabyasachi Baboo; Claudia Flynn; Katherine McKenney; Eugenia Salcedo; Xiaoya Zhou; Oleksandr Kalyuzhniy; Erik Georgeson; Nicole Phelps; Danny Lu; Saman Eskandarzadeh; Sergey Menis; Michael Kubitz; Bettina Groschel; Nushin Alavi; Abigail M. Jackson; Wen-Hsin Lee; Andy S. Tran; Elana Ben-Akiva; Katarzyna Kaczmarek Michaels; Jolene K. Diedrich; Chiamaka A. Enemuo; Vanessa Lewis; Arpan Pradhan; Sudhir Pai Kasturi; Torben Schiffner; Jon M. Steichen; Diane G. Carnathan; Sunny Himansu; John R. Yates; James C. Paulson; Gabriel Ozorowski; Darrell J. Irvine; Guido Silvestri; Devin Sok; Andrew B. Ward; Shane Crotty; William R. Schief

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Diverse priming outcomes under conditions of very rare precursor B cells

IMMUNITY

IF26.3

2025-04-01

OAAI

Madden, Patrick J.; Marina-Zarate, Ester; Rodrigues, Kristen A.; Steichen, Jon M.; Shil, Monolina; Ni, Kaiyuan; Michaels, Katarzyna Kaczmarek; Maiorino, Laura; Upadhyay, Amit A.; Saha, Swati; Pradhan, Arpan; Kalyuzhiny, Oleksandr; Liguori, Alessia; Lopez, Paul G.; Phung, Ivy; Flynn, Claudia; Zhou, Amelia; Melo, Mariane B.; Lemnios, Ashley; Phelps, Nicole; Georgeson, Erik; Alavi, Nushin; Kubitz, Michael; Lu, Danny; Eskandarzadeh, Saman; Metz, Amanda; Rodriguez, Oscar L.; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Healy, Brandon S.; Lim, Deuk; Lewis, Vanessa R.; Ben-Akiva, Elana; Pinney III, William; Gregory, Justin; Xiao, Shuhao; Carnathan, Diane G.; Kasturi, Sudhir Pai; Watson, Corey T.; Bosinger, Steven E.; Silvestri, Guido; Schief, William R.; Irvine, Darrell J.; Crotty, Shane

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Vaccination induces broadly neutralizing antibody precursors to HIV gp41 (vol 25, pg 1073, 2024)

NATURE IMMUNOLOGY

IF27.6

2024-06-14

OAAI

Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; McKenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schultze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.

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Vaccination induces broadly neutralizing antibody precursors to HIV gp41

NATURE IMMUNOLOGY

IF27.6

2024-05-30

OAAI

Schiffner, Torben; Phung, Ivy; Ray, Rashmi; Irimia, Adriana; Tian, Ming; Swanson, Olivia; Lee, Jeong Hyun; Lee, Chang-Chun D.; Marina-Zarate, Ester; Cho, So Yeon; Huang, Jiachen; Ozorowski, Gabriel; Skog, Patrick D.; Serra, Andreia M.; Rantalainen, Kimmo; Allen, Joel D.; Baboo, Sabyasachi; Rodriguez, Oscar L.; Himansu, Sunny; Zhou, Jianfu; Hurtado, Jonathan; Flynn, Claudia T.; Mckenney, Katherine; Havenar-Daughton, Colin; Saha, Swati; Shields, Kaitlyn; Schulze, Steven; Smith, Melissa L.; Liang, Chi-Hui; Toy, Laura; Pecetta, Simone; Lin, Ying-Cing; Willis, Jordan R.; Sesterhenn, Fabian; Kulp, Daniel W.; Hu, Xiaozhen; Cottrell, Christopher A.; Zhou, Xiaoya; Ruiz, Jennifer; Wang, Xuesong; Nair, Usha; Kirsch, Kathrin H.; Cheng, Hwei-Ling; Davis, Jillian; Kalyuzhniy, Oleksandr; Liguori, Alessia; Diedrich, Jolene K.; Ngo, Julia T.; Lewis, Vanessa; Phelps, Nicole; Tingle, Ryan D.; Spencer, Skye; Georgeson, Erik; Adachi, Yumiko; Kubitz, Michael; Eskandarzadeh, Saman; Elsliger, Marc A.; Amara, Rama R.; Landais, Elise; Briney, Bryan; Burton, Dennis R.; Carnathan, Diane G.; Silvestri, Guido; Watson, Corey T.; Yates III, John R.; Paulson, James C.; Crispin, Max; Grigoryan, Gevorg; Ward, Andrew B.; Sok, Devin; Alt, Frederick W.; Wilson, Ian A.; Batista, Facundo D.; Crotty, Shane; Schief, William R.

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Heterologous prime-boost vaccination drives early maturation of HIV broadly neutralizing antibody precursors in humanized mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-05-22

OAAI

Cottrell, Christopher A.; Hu, Xiaozhen; Lee, Jeong Hyun; Skog, Patrick; Luo, Sai; Flynn, Claudia T.; McKenney, Katherine R.; Hurtado, Jonathan; Kalyuzhniy, Oleksandr; Liguori, Alessia; Willis, Jordan R.; Landais, Elise; Raemisch, Sebastian; Chen, Xuejun; Baboo, Sabyasachi; Himansu, Sunny; Diedrich, Jolene K.; Duan, Hongying; Cheng, Cheng; Schiffner, Torben; Bader, Daniel L. V.; Kulp, Daniel W.; Tingle, Ryan; Georgeson, Erik; Eskandarzadeh, Saman; Alavi, Nushin; Lu, Danny; Sincomb, Troy; Kubitz, Michael; Mullen, Tina-Marie; Yates, John R., III; Paulson, James C.; Mascola, John R.; Alt, Frederick W.; Briney, Bryan; Sok, Devin; Schief, William R.

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Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice

COMMUNICATIONS BIOLOGY

IF5.1

2020-10-16

OAAI

Kimura, Taishi; Flynn, Claudia T.; Whitton, J. Lindsay

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A food-responsive switch modulates TFEB and autophagy, and determines susceptibility to coxsackievirus infection and pancreatitis

AUTOPHAGY

IF14.3

2020-02-04

OAAI

Alirezaei, Mehrdad; Flynn, Claudia T.; Garcia, Selma D.; Kimura, Taishi; Whitton, J. Lindsay

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Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

PLOS PATHOGENS

IF4.9

2019-04-08

OAAI

Kimura, Taishi; Flynn, Claudia T.; Alirezaei, Mehrdad; Sen, Ganes C.; Whitton, J. Lindsay

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Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

MEDIATORS OF INFLAMMATION

IF4.2

2017-01-01

OAAI

Bortell, Nikki; Flynn, Claudia; Conti, Bruno; Fox, Howard S.; Marcondes, Maria Cecilia G.

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Type I IFN Signaling Is Dispensable during Secondary Viral Infection

PLOS PATHOGENS

IF4.9

2016-08-31

OAAI

Hosking, Martin P.; Flynn, Claudia T.; Whitton, J. Lindsay

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Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo

AUTOPHAGY

IF14.3

2015-08-14

OAAI

Alirezaei, Mehrdad; Flynn, Claudia T.; Wood, Malcolm R.; Harkins, Stephanie; Whitton, J. Lindsay

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Interactions between enteroviruses and autophagy in vivo

AUTOPHAGY

IF14.3

2014-10-27

OAAI

Alirezaei, Mehrdad; Flynn, Claudia T.; Whitton, J. Lindsay

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Short-term fasting induces profound neuronal autophagy

AUTOPHAGY

IF14.3

2014-10-27

236

OAAI

Alirezaei, Mehrdad; Kemball, Christopher C.; Flynn, Claudia T.; Wood, Malcolm R.; Whitton, J. Lindsay; Kiosses, William B.

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Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis

AUTOPHAGY

IF14.3

2014-10-27

152

OAAI

Alirezaei, Mehrdad; Fox, Howard S.; Flynn, Claudia T.; Moore, Craig S.; Hebb, Andrea L. O.; Frausto, Ricardo F.; Bhan, Virender; Kiosses, William B.; Whitton, J. Lindsay; Robertson, George S.; Crocker, Stephen J.

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Antigen-Specific Naive CD8+ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect

JOURNAL OF IMMUNOLOGY

IF3.4

2014-08-15

OAAI

Hosking, Martin P.; Flynn, Claudia T.; Whitton, J. Lindsay

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CD8+ T Cells Maintain Suppression of Simian Immunodeficiency Virus in the Central Nervous System

JOURNAL OF INFECTIOUS DISEASES

IF4.5

2014-07-17