Not logged inTargeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic
Kamoun, Walid; Swindell, Elden; Pien, Christine; Luus, Lia; Cain, Jason; Pham, Minh; Kandela, Irawati; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Koshkaryev, Alexander; Askoxylakis, Vasileios; Kirpotin, Dmitri B.; Bloom, Troy; Mino-Kenudson, Mari; Marks, James D.; Zalutskaya, Alena; Bshara, Wiam; Morrison, Carl; Drummond, Daryl C. .png)
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SaveSynergy between EphA2-ILs-DTXp, a Novel EphA2-Targeted Nanoliposomal Taxane, and PD-1 Inhibitors in Preclinical Tumor ModelsKamoun, Walid S.; Dugast, Anne-Sophie; Suchy, James J.; Grabow, Stephanie; Fulton, Ross B.; Sampson, James F.; Luus, Lia; Santiago, Michael; Koshkaryev, Alexander; Sun, Gang; Askoxylakis, Vasileios; Tam, Eric; Huang, Zhaohua Richard; Drummond, Daryl C.; Sawyer, Andrew J. Share Save Antibody-mediated targeting of TNFR2 activates CD8+ T cells in mice and promotes antitumor immunityTam, Eric M.; Fulton, Ross B.; Sampson, James F.; Muda, Marco; Camblin, Adam; Richards, Jennifer; Koshkaryev, Alexander; Tang, Jian; Kurella, Vinodh; Jiao, Yang; Xu, Lihui; Zhang, Kathy; Kohli, Neeraj; Luus, Lia; Hutto, Elizabeth; Kumar, Sandeep; Lulo, James; Paragas, Violette; Wong, Christina; Suchy, James; Grabow, Stephanie; Dugast, Anne-Sophie; Zhang, Hong; Depis, Fabien; Feau, Sonia; Jakubowski, Aniela; Qiao, Wenlian; Craig, Galina; Razlog, Maja; Qiu, James; Zhou, Yu; Marks, James D.; Croft, Michael; Drummond, Daryl C.; Raue, Andreas Share Save Formulation optimization of an ephrin A2 targeted immunoliposome encapsulating reversibly modified taxane prodrugsHuang, Zhaohua Richard; Tipparaju, Suresh Kumar; Kirpotin, Dmitri B.; Pien, Christine; Kornaga, Tad; Noble, Charles O.; Koshkaryev, Alexander; Tran, Jimmy; Kamoun, Walid S.; Drummond, Daryl C. Share Save Mechanism of action of a novel agonist TNFR2 antibody that induces co-stimulation of T cells and promotes robust anti-tumor immunityFulton, Ross B.; Camblin, Adam; Sampson, James F.; Richards, Jennifer; Wong, Christina; Koshkaryev, Alexander; Luus, Lia; Jiao, Yang; Xu, Lihui; Paragas, Violette; Razlog, Maja; Muda, Marco; Tam, Eric M.; Drummond, Daryl C.; Raue, Andreas Share Save MM-401, a novel anti-TNFR2 antibody that induces T cell co-stimulation, robust anti-tumor activity and immune memoryRichards, Jennifer; Wong, Christina; Koshkaryev, Alexander; Fulton, Ross; Camblin, Adam; Sampson, James; Luus, Lia; Suchy, James; Grabow, Stephanie; Kurella, Vinodh; Kumar, Sandeep; Lulo, James; Qiu, James; Jiao, Yang; Xu, Lihui; Paragas, Violette; Razlog, Maja; Muda, Marco; Tam, Eric; Raue, Andreas; Drummond, Daryl Share Save Share Save Engineering and preclinical activity of MM-201, a best-in-class TRAIL receptor agonistSawyer, Andrew J.; Ghassemifar, Sara; Wong, Christina; Richards, Jennifer; Grabow, Stephanie; Suchy, James; Koshkaryev, Alexander; Razlog, Maja; Tam, Eric; Drummond, Daryl C. Share Save Antitumour activity and tolerability of an EphA2-targeted nanotherapeutic in multiple mouse modelsKamoun, Walid S.; Kirpotin, Dmitri B.; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Noble, Charles O.; Hayes, Mark E.; Luus, Lia; Koshkaryev, Alexander; Kim, Jaeyeon; Olivier, Ken; Kornaga, Tad; Oyama, Shinji; Askoxylakis, Vasileios; Pien, Christine; Kuesters, Geoffrey; Dumont, Nancy; Lugovskoy, Alexey A.; Schihl, Sarah A.; Wilton, John H.; Geddie, Melissa L.; Suchy, James; Grabow, Stephanie; Kohli, Neeraj; Reynolds, C. Patrick; Blaydes, Rachel; Zhou, Yu; Sawyer, Andrew J.; Marks, James D.; Drummond, Daryl C. Share Save Share Save Share Save Share Save Mechanisms of synergy of carboplatin and an EphA2-targeted docetaxel antibody-directed nanotherapeuticKamoun, Walid S.; Sawyer, Andrew J.; Pien, Christine; Koshkaryev, Alexander; Luus, Lia; Merrigan, Samantha; Sun, Gang; Kozin, Sergey; Huang, Zhaohua Richard; Tipparaju, Suresh K.; Kirpotin, Dmitri B.; Xu, Hannah; Askoxylakis, Vasileios; Reynolds, Patrick C.; Drummond, Daryl C. Share Save Nanoliposomal targeting of ephrin receptor A2 (EphA2): Preclinical in vitro and in vivo rationaleKamoun, Walid S.; Luus, Lia; Pien, Christine; Kornaga, Tad; Oyama, Shinji; Huang, Zhaohua Richard; Tipparaju, Suresh; Kirpotin, Dmitri B.; Marks, James D.; Koshkaryev, Alexander; Geddie, Melissa; Xu, Lihui; Lugovosky, Alexey; Drummond, Daryl C. Share Save Differential tissue clearance results in improved therapeutic index for irinotecan liposome injection (ONIVYDE) when combined with the PARP inhibitor veliparib in preclinical cervical tumorsKoshkaryev, Alexander; Fitzgerald, Jonathan; Kim, Jaeyeon; Kalra, Ashish; Kamoun, Walid; Blanchette, Sarah; Luus, Lia; Klinz, Stephan; Alkan, Ozan; Kornaga, Tad; Bates, Susan; Pommier, Yves; Drummond, Daryl C. Share Save MM-310, a novel EphA2-targeted docetaxel nanoliposomeKirpotin, Dmitri B.; Tipparaju, Suresh; Huang, Zhaohua Richard; Kamoun, VValid S.; Pien, Christine; Kornaga, Tad; Oyama, Shinji; Olivier, Ken; Marks, James D.; Koshkaryev, Alexander; Schihl, Sarah S.; Fetterly, Gerald; Schoeberl, Birgit; Noble, Charles; Hayes, Mark; Drummond, Daryl C. Share Save Share Save Share Save Share Save Share Save 
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