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Leonard S. Jefferson

pennsylvania commonwealth system of higher education (pcshe)

91H-index
465Paper Count
2.6WCitation Count
Published Papers 99
Publication Date
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Glucose-Induced Activation of mTORC1 is Associated with Hexokinase2 Binding to Sestrins in HEK293T Cells
errJOURNAL OF NUTRITION
IF3.8
err2023-04-01
err4
errOAAI
errRoberson, Paul A.; Kincheloe, Gregory N.; Welles, Jaclyn E.; Xu, Dandan; -Clarke, Mahalia Sam; MacLean, Paul S.; Lang, Charles H.; Jefferson, Leonard S.; Kimball, Scot R.
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errSave
The GCN2 eIF2α kinase is required for adaptation to amino acid deprivation in mice
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err456
errOAAI
errZhang, PC; McGrath, BC; Reinert, J; Olsen, DS; Lei, L; Gill, S; Wek, SA; Vattem, KM; Wek, RC; Kimball, SR; Jefferson, LS; Cavener, DR
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errSave
Loss of 4E-BPs prevents the hindlimb immobilization-induced decrease in protein synthesis in skeletal muscle
errJOURNAL OF APPLIED PHYSIOLOGY
IF3.3
err2023-01-01
err4
errOAAI
errKincheloe, Gregory N.; Roberson, Paul A.; Toro, Allyson L.; Stanley, Bruce A.; Stanley, Anne E.; Jefferson, Leonard S.; Dennis, Michael D.; Kimball, Scot R.
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errSave
An integrative approach to assessing effects of a short-term Western diet on gene expression in rat liver
errFRONTIERS IN ENDOCRINOLOGY
IF4.6
err2022-10-26
err2
errOAAI
errWelles, Jaclyn E.; Lacko, Holly; Kawasawa, Yuka Imamura; Dennis, Michael D.; Jefferson, Leonard S.; Kimball, Scot R.
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errSave
Convergence of signaling pathways in mediating actions of leucine and IGF-1 on mTORC1 in L6 myoblasts
errAMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
IF4.7
err2022-09-01
err4
errOAAI
errRoberson, Paul A.; Jefferson, Leonard S.; Kimball, Scot R.
errShare
errSave
Glucose Availability Regulates Sestrin3 Binding to Hexokinase2 to Affect Glucose-induced mTORC1 Activation
errFASEB JOURNAL
IF4.2
err2022-05-13
err0
PREAI
errRoberson, Paul A.; Welles, Jaclyn E.; Xu, Dandan; Kincheloe, Gregory N.; Jefferson, Leonard S.; Kimball, Scot R.
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errSave
A time course for markers of protein synthesis and degradation with hindlimb unloading and the accompanying anabolic resistance to refeeding
errJOURNAL OF APPLIED PHYSIOLOGY
IF3.3
err2020-07-01
err18
errOAAI
errRoberson, Paul A.; Shimkus, Kevin L.; Welles, Jaclyn E.; Xu, Dandan; Whitsell, Abigale L.; Kimball, Eric M.; Jefferson, Leonard S.; Kimball, Scot R.
errShare
errSave
ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation
errJOURNAL OF NUTRITION
IF3.8
err2020-05-01
err46
errOAAI
errXu, Dandan; Dai, Weiwei; Kutzler, Lydia; Lacko, Holly A.; Jefferson, Leonard S.; Dennis, Michael D.; Kimball, Scot R.
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errSave
O-GlcNAcylation alters the selection of mRNAs for translation and promotes 4E-BP1-dependent mitochondrial dysfunction in the retina
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2019-04-01
err25
errOAAI
errDierschke, Sadie K.; Miller, William P.; Favate, John S.; Shah, Premal; Kawasawa, Yuka Imamura; Salzberg, Anna C.; Kimball, Scot R.; Jefferson, Leonard S.; Dennis, Michael D.
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errSave
Dietary Fat Quantity and Type Induce Transcriptome-Wide Effects on Alternative Splicing of Pre-mRNA in Rat Skeletal Muscle
errJOURNAL OF NUTRITION
IF3.8
err2017-09-01
err14
errOAAI
errBlack, Adam J.; Ravi, Suhana; Jefferson, Leonard S.; Kimball, Scot R.; Schilder, Rudolf J.
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errSave
Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation
errCELLULAR SIGNALLING
IF3.7
err2016-08-01
err81
errOAAI
errKimball, Scot R.; Gordon, Bradley S.; Moyer, Jenna E.; Dennis, Michael D.; Jefferson, Leonard S.
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errSave
The Translational Repressor 4E-BP1 Contributes to Diabetes-Induced Visual Dysfunction
errINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
IF4.7
err2016-03-21
err24
errOAAI
errMiller, William P.; Mihailescu, Maria L.; Yang, Chen; Barber, Alistair J.; Kimball, Scot R.; Jefferson, Leonard S.; Dennis, Michael D.
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errSave
Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet
errJOURNAL OF NUTRITION
IF3.8
err2015-11-01
err27
errOAAI
errKimball, Scot R.; Ravi, Suhana; Gordon, Bradley S.; Dennis, Michael D.; Jefferson, Leonard S.
errShare
errSave
Nutrient-Induced Stimulation of Protein Synthesis in Mouse Skeletal Muscle Is Limited by the mTORC1 Repressor REDD1
errJOURNAL OF NUTRITION
IF3.8
err2015-04-01
err50
errOAAI
errGordon, Bradley S.; Williamson, David L.; Lang, Charles H.; Jefferson, Leonard S.; Kimball, Scot R.
errShare
errSave
Regulated in Development and DNA Damage 1 Is Necessary for Hyperglycemia-induced Vascular Endothelial Growth Factor Expression in the Retina of Diabetic Rodents
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2015-02-01
err53
errOAAI
errDennis, Michael D.; Kimball, Scot R.; Fort, Patrice E.; Jefferson, Leonard S.
errShare
errSave
ALCAT1 Controls Mitochondrial Etiology of Fatty Liver Diseases, Linking Defective Mitophagy to Steatosis
errHEPATOLOGY
IF15.8
err2015-01-20
err131
errOAAI
errWang, Li; Liu, Xiaolei; Nie, Jia; Zhang, Jun; Kimball, Scot R.; Zhang, Hai; Zhang, Weiping J.; Jefferson, Leonard S.; Cheng, Zeneng; Ji, Qiuhe; Shi, Yuguang
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errSave
Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells
errAUTOPHAGY
IF14.3
err2014-10-27
err68
errOAAI
errCheng, Yan; Ren, Xingcong; Zhang, Yi; Shan, Yu; Huber-Keener, Kathryn J.; Zhang, Li; Kimball, Scot R.; Harvey, Harold; Jefferson, Leonard S.; Yang, Jin-Ming
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errSave
mTORC1-Independent Reduction of Retinal Protein Synthesis in Type 1 Diabetes
errDIABETES
IF7.5
err2014-08-16
err25
errOAAI
errFort, Patrice E.; Losiewicz, Mandy K.; Pennathur, Subramaniam; Jefferson, Leonard S.; Kimball, Scot R.; Abcouwer, Steven F.; Gardner, Thomas W.
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errSave
REDD1 enhances protein phosphatase 2A-mediated dephosphorylation of Akt to repress mTORC1 signaling
errSCIENCE SIGNALING
IF6.6
err2014-07-22
err131
errOAAI
errDennis, Michael D.; Coleman, Catherine S.; Berg, Arthur; Jefferson, Leonard S.; Kimball, Scot R.
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errSave
RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells
errCELLULAR SIGNALLING
IF3.7
err2014-03-01
err54
errOAAI
errGordon, Bradley S.; Kazi, Abid A.; Coleman, Catherine S.; Dennis, Michael D.; Chau, Vincent; Jefferson, Leonard S.; Kimball, Scot R.
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
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Nahum Sonenberg
H-index: 178 · Papers: 957
J
Joshua R. Sanes
H-index: 146 · Papers: 446
G
Guoyao Wu
H-index: 132 · Papers: 725
D
David Ron
H-index: 130 · Papers: 421
张
张丽 (Li Zhang)
H-index: 121 · Papers: 2.6K
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