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D

David Ron

university of cambridge

130H-index
421Paper Count
9.6WCitation Count
Published Papers 175
Publication Date
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A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response
errNature Communications
IF15.7
err2026-05-06
err0
errOAAI
errFiona Shilliday; Miguel Gancedo-Rodrigo; Ginto George; Shintaro Aibara; Santosh Adhikari; Syedah Neha Ashraf; Evelyne J. Barrey; Paolo A. Centrella; Damian Crowther; Paige Dickson; Diana Gikunju; Marie-Aude Guié; John P. Guilinger; Anders Gunnarsson; Heather P. Harding; Christopher D. Hupp; Rachael Jetson; Anthony D. Keefe; JeeSoo Monica Kim; Richard J. Lewis; Taiana Maia de Oliveira; Jennifer Le-Marshall; Usha Narayanan; Katherine A. Nugai; Dušan Petrović; Emma Rivers; David Ron; Daisy Stringfellow; Karl Syson; Lewis Ward; John T. S. Yeoman; Yan Yu; Ying Zhang; Alisa Zyryanova; David J. Baker; Perla Breccia; John E. Linley
errShare
errSave
A structural basis for chaperone repression of stress signaling from the endoplasmic reticulum
errMolecular Cell
IF16.6
err2025-10-23
err0
errOAAI
errLisa Neidhardt; Joanne Tung; Miriam Kuchersky; Jakub Milczarek; Vasileios Kargas; Katherine Stott; Rina Rosenzweig; David Ron; Yahui Yan
errShare
errSave
Alternating binding and p97-mediated dissociation of SDS22 and I3 recycles active PP1 between holophosphatases
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-08-29
err0
errOAAI
errKueck, Anja F.; van den Boom, Johannes; Koska, Sandra; Ron, David; Meyer, Hemmo
errShare
errSave
A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
errELIFE
IF0
err2024-07-29
err2
errOAAI
errTung, Joanne; Huang, Lei; George, Ginto; Harding, Heather P.; Ron, David; Ordonez, Adriana
errShare
errSave
Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-03-28
err1
errOAAI
errYan, Yahui; Shetty, Maithili; Harding, Heather P.; George, Ginto; Zyryanova, Alisa; Labbe, Katherine; Mafi, Amirhossein; Hao, Qi; Sidrauski, Carmela; Ron, David; Hinnebusch, Alan
errShare
errSave
J-domain proteins: From molecular mechanisms to diseases
errCELL STRESS & CHAPERONES
IF3.2
err2024-02-01
err7
errOAAI
errMarszalek, Jaroslaw; De Los Rios, Paolo; Cyr, Douglas; Mayer, Matthias P.; Adupa, Vasista; Andreasson, Claes; Blatch, Gregory L.; Braun, Janice E. A.; Brodsky, Jeffrey L.; Bukau, Bernd; Chapple, J. Paul; Conz, Charlotte; Dementin, Sebastien; Genevaux, Pierre; Genest, Olivier; Goloubinoff, Pierre; Gestwicki, Jason; Hammond, Colin M.; Hines, Justin K.; Ishikawa, Koji; Joachimiak, Lukasz A.; Kirstein, Janine; Liberek, Krzysztof; Mokranjac, Dejana; Nillegoda, Nadinath; Ramos, Carlos H. I.; Rebeaud, Mathieu; Ron, David; Rospert, Sabine; Sahi, Chandan; Shalgi, Reut; Tomiczek, Bartlomiej; Ushioda, Ryo; Ustyantseva, Elizaveta; Ye, Yihong; Zylicz, Maciej; Kampinga, Harm H.
errShare
errSave
The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells
errEMBO JOURNAL
IF8.3
err2023-12-18
err8
errOAAI
errNeidhardt, Lisa; Cloots, Eva; Friemel, Natalie; Weiss, Caroline A. M.; Harding, Heather P.; Mclaughlin, Stephen H.; Janssens, Sophie; Ron, David
errShare
errSave
Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1α
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-28
err237
errOAAI
errMarcu, MG; Doyle, M; Bertolotti, A; Ron, D; Hendershot, L; Neckers, L
errShare
errSave
Activating transcription factor 4 is translationally regulated by hypoxic stress
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err448
errOAAI
errBlais, JD; Filipenko, V; Bi, MX; Harding, HP; Ron, D; Koumenis, C; Wouters, BG; Bell, JC
errShare
errSave
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err502
errOAAI
errJiang, HY; Wek, SA; McGrath, BC; Lu, D; Hai, TW; Harding, HP; Wang, XZ; Ron, D; Cavener, DR; Wek, RC
errShare
errSave
Role for activating transcription factor 3 in stress-induced β-cell apoptosis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err312
errOAAI
errHartman, MG; Lu, D; Kim, ML; Kociba, GJ; Shukri, T; Buteau, J; Wang, XZ; Frankel, WL; Guttridge, D; Prentki, M; Grey, ST; Ron, D; Hai, TW
errShare
errSave
Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err639
errOAAI
errDeng, J; Lu, PD; Zhang, YH; Scheuner, D; Kaufman, RJ; Sonenberg, N; Harding, HP; Ron, D
errShare
errSave
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err287
errOAAI
errBlais, Jaime D.; Addison, Christina L.; Edge, Robert; Falls, Theresa; Zhao, Huijun; Wary, Kishore; Koumenis, Costas; Harding, Heather P.; Ron, David; Holcik, Martin; Bell, John C.
errShare
errSave
Inhibition of Nonsense-Mediated RNA Decay by the Tumor Microenvironment Promotes Tumorigenesis
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err144
errOAAI
errWang, Ding; Zavadil, Jiri; Martin, Leenus; Parisi, Fabio; Friedman, Eugene; Levy, David; Harding, Heather; Ron, David; Gardner, Lawrence B.
errShare
errSave
GCN2-Dependent Metabolic Stress Is Essential for Endotoxemic Cytokine Induction and Pathology
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-20
err74
errOAAI
errLiu, Haiyun; Huang, Lei; Bradley, Jillian; Liu, Kebin; Bardhan, Kankana; Ron, David; Mellor, Andrew L.; Munn, David H.; McGaha, Tracy L.
errShare
errSave
Infancy-onset diabetes caused by de-regulated AMPylation of the human endoplasmic reticulum chaperone BiP
errEMBO MOLECULAR MEDICINE
IF8.3
err2023-01-27
err6
errOAAI
errPerera, Luke A.; Hattersley, Andrew T.; Harding, Heather P.; Wakeling, Matthew N.; Flanagan, Sarah E.; Mohsina, Ibrahim; Raza, Jamal; Gardham, Alice; Ron, David; De Franco, Elisa
errShare
errSave
AMPylation and Endoplasmic Reticulum Protein Folding Homeostasis
errcold spring harbor perspectives in medicine
IF8.4
err2022-08-30
err7
errOAAI
errPerera, Luke A. A.; Ron, David
errShare
errSave
Pharmacological targeting of endoplasmic reticulum stress in disease
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2021-10-26
err264
PREAI
errMarciniak, Stefan J.; Chambers, Joseph E.; Ron, David
errShare
errSave
Higher-order phosphatase-substrate contacts terminate the integrated stress response
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2021-10-08
err14
errOAAI
errYan, Yahui; Harding, Heather P.; Ron, David
errShare
errSave
Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD
errNATURE COMMUNICATIONS
IF15.7
err2021-08-18
err11
errOAAI
errPerera, Luke A.; Preissler, Steffen; Zaccai, Nathan R.; Prevost, Sylvain; Devos, Juliette M.; Haertlein, Michael; Ron, David
errShare
errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
D
Dennis W. Dickson
H-index: 218 · Papers: 2.3K
G
Gerald I. Shulman
H-index: 183 · Papers: 819
N
Nahum Sonenberg
H-index: 178 · Papers: 957
P
Peter J. Campbell
H-index: 159 · Papers: 746
R
Randal J. Kaufman
H-index: 158 · Papers: 639
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