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Paul F. Hollenberg

ETH Zurich

54H-index
333Paper Count
10.0KCitation Count
Published Papers 62
Publication Date
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Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 CYP2B4 and NADPH-cytochrome P450 oxidoreductase
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2021-01-01
err4
errOAAI
errCheng, Shen; Bo, Zhiyuan; Hollenberg, Paul; Osawa, Yoichi; Zhang, Haoming
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The full-length cytochrome P450 enzyme CYP102A1 dimerizes at its reductase domains and has flexible heme domains for efficient catalysis
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2018-05-01
err44
errOAAI
errZhang, Haoming; Yokom, Adam L.; Cheng, Shen; Su, Min; Hollenberg, Paul F.; Southworth, Daniel R.; Osawa, Yoichi
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Significant Improvement of Antithrombotic Responses to Clopidogrel by Use of a Novel Conjugate as Revealed in an Arterial Model of Thrombosiss
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2016-10-01
err13
errOAAI
errZhang, Haoming; Lauver, D. Adam; Wang, Hui; Sun, Duxin; Hollenberg, Paul F.; Chen, Y. Eugene; Osawa, Yoichi; Eitzman, Daniel T.
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Oxidative hemoglobin reactions: Applications to drug metabolism
errARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
IF3
err2016-06-01
err11
PREAI
errSpolitak, Tatyana; Hollenberg, Paul F.; Ballou, David P.
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errSave
Using a cell based model system to characterize CYP17A1 genetic variants
errCANCER RESEARCH
IF16.6
err2015-08-01
err0
PREAI
errCapper, Cameron P.; Liu, Jiayan; McIntosh, Lauren; Larios, Jose M.; Johnson, Michael D.; Hollenberg, Paul F.; Auchus, Richard J.; Rae, James M.
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errSave
Systems Toxicology: A Special Issue
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2014-03-17
err2
PREAI
errSturla, Shana J.; Hollenberg, Paul
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errSave
Formation, Reactivity, and Antiplatelet Activity of Mixed Disulfide Conjugates of Clopidogrel
errMOLECULAR PHARMACOLOGY
IF3
err2013-04-01
err18
errOAAI
errZhang, Haoming; Lauver, D. Adam; Lucchesi, Benedict R.; Hollenberg, Paul F.
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Formation of the Thiol Conjugates and Active Metabolite of Clopidogrel by Human Liver Microsomes
errMOLECULAR PHARMACOLOGY
IF3
err2012-08-01
err28
errOAAI
errZhang, Haoming; Lau, Wei C.; Hollenberg, Paul F.
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Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Clopidogrel: Involvement of Both Covalent Modification of Cysteinyl Residue 475 and Loss of Heme
errMOLECULAR PHARMACOLOGY
IF3
err2011-11-01
err40
errOAAI
errZhang, Haoming; Amunugama, Hemali; Ney, Sarah; Cooper, Nyemade; Hollenberg, Paul F.
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errSave
Polymorphic Variants of Cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) Exhibit Altered Rates of Metabolism for Bupropion and Efavirenz: A Charge-Reversal Mutation in the K139E Variant (CYP2B6.8) Impairs Formation of a Functional Cytochrome P450-Reductase Complex
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2011-09-01
err61
errOAAI
errZhang, Haoming; Sridar, Chitra; Kenaan, Cesar; Amunugama, Hemali; Ballou, David P.; Hollenberg, Paul F.
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errSave
Covalent Modification of Thr302 in Cytochrome P450 2B1 by the Mechanism-Based Inactivator 4-tert-Butylphenylacetylene
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2010-06-01
err16
errOAAI
errLin, Hsia-lien; Zhang, Haoming; Jushchyshyn, Monica; Hollenberg, Paul F.
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errSave
Cross-linking of human cytochrome P450 2B6 to NADPH-cytochrome P450 reductase: Identification of a potential site of interaction
errJOURNAL OF INORGANIC BIOCHEMISTRY
IF3.2
err2010-04-01
err35
errOAAI
errBumpus, Namandje N.; Hollenberg, Paul F.
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Gender Dimorphic Formation of Mouse Mallory-Denk Bodies and the Role of Xenobiotic Metabolism and Oxidative Stress
errGASTROENTEROLOGY
IF25.1
err2010-04-01
err44
errOAAI
errHanada, Shinichiro; Snider, Natasha T.; Brunt, Elizabeth M.; Hollenberg, Paul F.; Omary, M. Bishr
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errSave
Defining the Structural Consequences of Mechanism-Based Inactivation of Mammalian Cytochrome P450 2B4 Using Resonance Raman Spectroscopy
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2010-01-15
err17
errOAAI
errMak, Piotr J.; Zhang, Haoming; Hollenberg, Paul F.; Kincaid, James R.
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errSave
Mechanism-Based Inactivation of CYP2B1 and Its F-Helix Mutant by Two tert-Butyl Acetylenic Compounds: Covalent Modification of Prosthetic Heme Versus Apoprotein
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2009-11-01
err10
errOAAI
errLin, Hsia-lien; Zhang, Haoming; Noon, Kathleen R.; Hollenberg, Paul F.
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errSave
tert-Butylphenylacetylene Is a Potent Mechanism-Based Inactivator of Cytochrome P450 2B4: Inhibition of Cytochrome P450 Catalysis by Steric Hindrance
errMOLECULAR PHARMACOLOGY
IF3
err2009-11-01
err23
errOAAI
errZhang, Haoming; Lin, Hsia-lien; Walker, Vyvyca J.; Hamdane, Djemel; Hollenberg, Paul F.
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errSave
Effect of Conformational Dynamics on Substrate Recognition and Specificity as Probed by the Introduction of a de Novo Disulfide Bond into Cytochrome P450 2B1
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2009-09-01
err33
errOAAI
errZhang, Haoming; Kenaan, Cesar; Hamdane, Djemel; Hoa, Gaston Hui Bon; Hollenberg, Paul F.
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Metabolic Activation of Mifepristone [RU486; 17β-Hydroxy-11β-(4-dimethylaminophenyl)-17α-(1-propynyl)-estra-4,9-dien-3-one] by Mammalian Cytochromes P450 and the Mechanism-Based Inactivation of Human CYP2B6
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2009-04-01
err19
errOAAI
errLin, Hsia-lien; Zhang, Haoming; Hollenberg, Paul F.
errShare
errSave
A Cytochrome P450-Derived Epoxygenated Metabolite of Anandamide Is a Potent Cannabinoid Receptor 2-Selective Agonist
errMOLECULAR PHARMACOLOGY
IF3
err2009-04-01
err87
errOAAI
errSnider, Natasha T.; Nast, James A.; Tesmer, Laura A.; Hollenberg, Paul F.
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errSave
Kinetics of Oxidation of Benzphetamine by Compounds I of Cytochrome P450 2B4 and Its Mutants
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2009-02-11
err30
errOAAI
errSheng, Xin; Zhang, Haoming; Im, Sang-Choul; Horner, John H.; Waskell, Lucy; Hollenberg, Paul F.; Newcomb, Martin
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errSave

Research Directions

No research directions
Co-authors
Cooperation Journals
S
Stephen J. Lippard
H-index: 144 · Papers: 1.5K
T
Thomas J. Giordano
H-index: 111 · Papers: 484
E
Elizabeth M. Brunt
H-index: 102 · Papers: 398
M
Minor J. Coon
H-index: 85 · Papers: 368
M
M. Bishr Omary
H-index: 83 · Papers: 369
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