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Stephen J. Lippard

Massachusetts Institute of Technology

144H-index
1.5KPaper Count
9.9WCitation Count
Published Papers 528
Publication Date
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Leveraging platinum-protein interactions to overcome chemoresistance
errNature Communications
IF15.7
err2025-10-20
err0
errOAAI
errFang Wang; Jonathan Braverman; George Eng; Ozen Leylek; Nicholas L. Petrone; Daniel S. Honeycutt; Shinya Imada; Brian Pallares; Daiyao Zhang; Jason M. Mrosla; Camellia S. Huang; Anna A. Griadunova; William K. McCarthy; Jacob M. Goldberg; Michael T. Hemann; Stephen J. Lippard; Ömer H. Yilmaz
errShare
errSave
Mobile zinc as a modulator of sensory perception
errFEBS LETTERS
IF3
err2022-12-20
err2
errOAAI
errGoldberg, Jacob M.; Lippard, Stephen J.
errShare
errSave
Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2020-11-17
err59
errOAAI
errReplogle, John Michael; Zhou, Wen; Amaro, Adrianna E.; McFarland, James M.; Villalobos-Ortiz, Mariana; Ryan, Jeremy; Letai, Anthony; Yilmaz, Omer; Sheltzer, Jason; Lippard, Stephen J.; Ben-David, Uri; Amon, Angelika
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errSave
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints
errNATURE COMMUNICATIONS
IF15.7
err2020-08-17
err18
errOAAI
errKong, Yi Wen; Dreaden, Erik C.; Morandell, Sandra; Zhou, Wen; Dhara, Sanjeev S.; Sriram, Ganapathy; Lam, Fred C.; Patterson, Jesse C.; Quadir, Mohiuddin; Anh Dinh; Shopsowitz, Kevin E.; Varmeh, Shohreh; Yilmaz, Omer H.; Lippard, Stephen J.; Reinhardt, H. Christian; Hemann, Michael T.; Hammond, Paula T.; Yaffe, Michael B.
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errSave
A Platinum(IV) Prodrug-Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2020-05-15
err27
errOAAI
errFadzen, Colin M.; Wolfe, Justin M.; Zhou, Wen; Cho, Choi-Fong; von Spreckelsen, Niklas; Hutchinson, Kathryn T.; Lee, Yen-Chun; Chiocca, E. Antonio; Lawler, Sean E.; Yilmaz, Omer H.; Lippard, Stephen J.; Pentelute, Bradley L.
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Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2020-03-16
err18
errOAAI
errLee, Miseon; Maji, Basudeb; Manna, Debasish; Kahraman, Sevim; Elgamal, Ruth; Small, Jonnell; Kokkonda, Praveen; Vetere, Amedeo; Goldberg, Jacob M.; Lippard, Stephen J.; Kulkarni, Rohit; Wagner, Bridget K.; Choudhary, Amit
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errSave
HaloTag-Based Hybrid Targetable and Ratiometric Sensors for Intracellular Zinc
errACS CHEMICAL BIOLOGY
IF3.8
err2020-01-09
err41
PREAI
errZastrow, Melissa L.; Huang, Zhen; Lippard, Stephen J.
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errSave
Sensing intracellular calcium ions using a manganese-based MRI contrast agent
errNATURE COMMUNICATIONS
IF15.7
err2019-02-22
err82
errOAAI
errBarandov, Ali; Badelle, Benjamin B.; Williamson, Catherine G.; Loucks, Emily S.; Lippard, Stephen J.; Jasanoff, Alan
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errSave
DNA Intercalation Facilitates Efficient DNA-Targeted Covalent Binding of Phenanthriplatin
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2019-01-02
err61
errOAAI
errAlmaqwashi, Ali A.; Zhou, Wen; Naufer, M. Nabuan; Riddell, Imogen A.; Yilmaz, Omer H.; Lippard, Stephen J.; Williams, Mark C.
errShare
errSave
Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn2+ allows tracking of lysosomal Zn2+ pools
errSCIENTIFIC REPORTS
IF3.9
err2018-10-09
err37
errOAAI
errHan, Yu; Goldberg, Jacob M.; Lippard, Stephen J.; Palmer, Amy E.
errShare
errSave
Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance
errNANO LETTERS
IF9.1
err2018-06-14
err189
errOAAI
errLing, Xiang; Chen, Xing; Riddell, Imogen A.; Tao, Wei; Wang, Junqing; Hollett, Geoffrey; Lippard, Stephen J.; Farokhzad, Omid C.; Shi, Jinjun; Wu, Jun
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errSave
Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations
errFRONTIERS IN CHEMISTRY
IF4.2
err2018-05-25
err24
errOAAI
errHucke, Anna; Park, Ga Young; Bauer, Oliver B.; Beyer, Georg; Koeppen, Christina; Zeeh, Dorothea; Wehe, Christoph A.; Sperling, Michael; Schroeter, Rita; Kantauskaite, Marta; Hagos, Yohannes; Karst, Uwe; Lippard, Stephen J.; Ciarimboli, Giuliano
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errSave
Speciation of Phenanthriplatin and Its Analogs in the Core of Tobacco Mosaic Virus
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-03-19
err30
errOAAI
errVernekar, Amit A.; Berger, Gilles; Czapar, Anna E.; Veliz, Frank A.; Wang, David I.; Steinmetz, Nicole F.; Lippard, Stephen J.
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errSave
Anticancer activity of osmium(VI) nitrido complexes in patient-derived glioblastoma initiating cells and in vivo mouse models
errCANCER LETTERS
IF10.1
err2018-03-01
err33
PREAI
errBerger, Gilles; Grauwet, Korneel; Zhang, Hong; Hussey, Amanda M.; Nowicki, Michal O.; Wang, David I.; Chiocca, E. Antonio; Lawler, Sean E.; Lippard, Stephen J.
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errSave
A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-02-12
err25
errOAAI
errRichardson, Christopher E. R.; Cunden, Lisa S.; Butty, Vincent L.; Nolan, Elizabeth M.; Lippard, Stephen J.; Shoulders, Matthew D.
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errSave
Photoactivatable Sensors for Detecting Mobile Zinc
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2018-01-31
err94
errOAAI
errGoldberg, Jacob M.; Wang, Fang; Sessler, Chanan D.; Vogler, Nathan W.; Zhang, Daniel Y.; Loucks, William H.; Tzounopoulos, Thanos; Lippard, Stephen J.
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errSave
Tuning the Diiron Core Geometry in Carboxylate-Bridged Macrocyclic Model Complexes Affects Their Redox Properties and Supports Oxidation Chemistry
errINORGANIC CHEMISTRY
IF4.7
err2017-09-05
err10
PREAI
errWang, Fang; Becker, Sabine; Minier, Mikael A.; Loas, Andrei; Jackson, Megan N.; Lippard, Stephen J.
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errSave
CF2H, a Hydrogen Bond Donor
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2017-06-27
err382
errOAAI
errSessler, Chanan D.; Rahm, Martin; Becker, Sabine; Goldberg, Jacob M.; Wang, Fang; Lippard, Stephen J.
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errSave
Challenges and Opportunities in Brain Bioinorganic Chemistry
errACCOUNTS OF CHEMICAL RESEARCH
IF17.7
err2017-03-21
err5
errOAAI
errGoldberg, Jacob M.; Lippard, Stephen J.
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errSave
A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress
errNATURE MEDICINE
IF50
err2017-02-27
err386
errOAAI
errBruno, Peter M.; Liu, Yunpeng; Park, Ga Young; Murai, Junko; Koch, Catherine E.; Eisen, Timothy J.; Pritchard, Justin R.; Pommier, Yves; Lippard, Stephen J.; Hemann, Michael T.
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Research Directions

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Co-authors
Cooperation Journals
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H-index: 262 · Papers: 2.0K
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H-index: 193 · Papers: 1.2K
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John F. Hartwig
H-index: 172 · Papers: 1.1K
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Jean M. J. Fréchet
H-index: 170 · Papers: 925
C
Chuan He
H-index: 161 · Papers: 978
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