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Leif Bertilsson

Karolinska Institutet

85H-index
404Paper Count
2.3WCitation Count
Published Papers 62
Publication Date
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Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers
errJOURNAL OF PERSONALIZED MEDICINE
IF3
err2021-05-24
err5
errOAAI
errLi, Xue-Qing; Thelingwani, Roslyn Stella; Bertilsson, Leif; Diczfalusy, Ulf; Andersson, Tommy B.; Masimirembwa, Collen
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Tribute to Folke Sjoqvist, a Pioneer in Clinical Pharmacology
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2020-07-08
err0
PREAI
errDahl, Marja-Liisa; Bergman, Ulf; Bertilsson, Leif; Eliasson, Erik; Gustafsson, Lars L.; Panagiotidis, Georgios; Rane, Anders
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Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype
errSCIENTIFIC REPORTS
IF3.9
err2018-11-05
err7
errOAAI
errKitabi, Eliford Ngaimisi; Minzi, Omary Mashiku Sylivester; Mugusi, Sabina; Sasi, Philip; Janabi, Mohamed; Mugusi, Ferdinand; Bertilsson, Leif; Burhenne, Jurgen; Aklillu, Eleni
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Population Pharmacokinetic Model Linking Plasma and Peripheral Blood Mononuclear Cell Concentrations of Efavirenz and Its Metabolite, 8-Hydroxy-Efavirenz, in HIV Patients
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2017-08-01
err12
errOAAI
errHabtewold, Abiy; Aklillu, Eleni; Makonnen, Eyasu; Yimer, Getnet; Bertilsson, Leif; Burhenne, Juergen; Owen, Joel S.
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Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment
errJOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
IF3.6
err2014-08-04
err23
errOAAI
errNgaimisi, E.; Minzi, O.; Mugusi, S.; Sasi, P.; Riedel, K. -D.; Suda, A.; Ueda, N.; Bakari, M.; Janabi, M.; Mugusi, F.; Bertilsson, L.; Burhenne, J.; Aklillu, E.; Diczfalusy, U.
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Pharmacogenetics of antidepressant, antiepileptic and neuroleptic drug treatment
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2013-10-01
err0
PREAI
errBertilsson, L.; Hatta, F. H.
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UGT1A4*3 Encodes Significantly Increased Glucuronidation of Olanzapine in Patients on Maintenance Treatment and in Recombinant Systems
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2012-06-20
err28
PREAI
errHaslemo, T.; Loryan, I.; Ueda, N.; Mannheimer, B.; Bertilsson, L.; Ingelman-Sundberg, M.; Molden, E.; Eliasson, E.
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Effect of Rifampicin and CYP2B6 Genotype on Long-Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2011-08-03
err77
PREAI
errNgaimisi, E.; Mugusi, S.; Minzi, O.; Sasi, P.; Riedel, K-D; Suda, A.; Ueda, N.; Janabi, M.; Mugusi, F.; Haefeli, W. E.; Bertilsson, L.; Burhenne, J.; Aklillu, E.
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4β-hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2011-01-10
err190
errOAAI
errDiczfalusy, Ulf; Nylen, Hanna; Elander, Pontus; Bertilsson, Leif
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ACTIVITY OF CYP3A IN MOTHERS AND THEIR NEWBORNS USING 4B-HYDROXYCHOLESTEROL AS A MARKER
errPEDIATRIC RESEARCH
IF3.1
err2010-11-01
err0
errOAAI
errWide, K.; Ekmark-Sergel, S.; Nylen, H.; Diczfalusy, U.; Bertilsson, L.
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Clinically Significant CYP2C Inhibition by Noscapine but Not by Glucosamine
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2010-07-28
err19
PREAI
errRosenborg, S.; Stenberg, M.; Otto, S.; Ostervall, J.; Masquelier, M.; Yue, Q-Y; Bertilsson, L.; Eliasson, E.
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MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2009-05-01
err37
PREAI
errHilli, Johanna; Heikkinen, Tuija; Rontu, Riikka; Lehtimaki, Terho; Kishida, Ikuko; Aklillu, Eleni; Bertilsson, Leif; Vahlberg, Tero; Laine, Kari
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Voriconazole Increases while Itraconazole Decreases Plasma Meloxicam Concentrations
errANTIMICROBIAL AGENTS AND CHEMOTHERAPY
IF4.5
err2009-02-01
err18
errOAAI
errHynninen, V. V.; Olkkola, K. T.; Bertilsson, L.; Kurkinen, K. J.; Korhonen, T.; Neuvonen, P. J.; Laine, K.
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errSave
4β-Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2008-12-22
err120
errOAAI
errDiczfalusy, Ulf; Kanebratt, Kajsa P.; Bredberg, Eva; Andersson, Tommy B.; Bottiger, Ylva; Bertilsson, Leif
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Cytochrome P450 Induction by Rifampicin in Healthy Subjects: Determination Using the Karolinska Cocktail and the Endogenous CYP3A4 Marker 4β-Hydroxycholesterol
errCLINICAL PHARMACOLOGY & THERAPEUTICS
IF5.5
err2008-07-23
err134
PREAI
errKanebratt, K. P.; Diczfalusy, U.; Backstrom, T.; Sparve, E.; Bredberg, E.; Bottiger, Y.; Andersson, T. B.; Bertilsson, L.
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Increased omeprazole metabolism in carriers of the CYP2C19*17 allele;: a pharmacokinetic study in healthy volunteers
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2008-02-20
err174
errOAAI
errBaldwin, R. Michael; Ohlsson, Staffan; Pedersen, Rasmus Steen; Mwinyi, Jessica; Ingelman-Sundberg, Magnus; Eliasson, Erik; Bertilsson, Leif
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Time course of the increase in 4β-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy
errBRITISH JOURNAL OF CLINICAL PHARMACOLOGY
IF3
err2008-02-13
err44
errOAAI
errWide, Katarina; Larsson, Hanna; Bertilsson, Leif; Diczfalusy, Ulf
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Monoamine metabolites level in CSF are related to the 5-HTT gene polymorphism in treatment-resistant depression
errEUROPEAN NEUROPSYCHOPHARMACOLOGY
IF6.7
err2007-10-01
err0
PREAI
errKishida, I.; Aklillu, E.; Kawanishi, C.; Bertilsson, L.; Agren, H.
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FLUOXETINE TREATMENT OF DEPRESSION - CLINICAL EFFECTS, DRUG CONCENTRATIONS AND MONOAMINE METABOLITES AND N-TERMINALLY EXTENDED SUBSTANCE-P IN CEREBROSPINAL-FLUID
errActa Psychiatrica Scandinavica
IF5
err2007-08-23
err97
PREAI
errMARTENSSON, B; NYBERG, S; TORESSON, G; BRODIN, E; BERTILSSON, L
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CSF MONOAMINE METABOLITES OF DEPRESSED-PATIENTS DURING ILLNESS AND AFTER RECOVERY
errActa Psychiatrica Scandinavica
IF5
err2007-08-23
err76
PREAI
errTRASKMANBENDZ, L; ASBERG, M; BERTILSSON, L; THOREN, P
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Research Directions

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Co-authors
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H-index: 103 · Papers: 718
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