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Gene reactivation upon erosion of X chromosome inactivation in female hiPSCs is predictable yet variable and persists through differentiation Raposo, Ana Claudia; Caldas, Paulo; Jeremias, Joana; Arez, Maria; Mateus, Francisca Cazaux; Barbosa, Pedro; Sousa-Luis, Rui; Agua, Frederico; Oxley, David; Mupo, Annalisa; Eckersley-Maslin, Melanie; Casanova, Miguel; Grosso, Ana Rita; da Rocha, Simao Teixeira Share Save
An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L Nic Aodha, Leah; Pokhilko, Alexandra; Rosen, Leah U.; Galatidou, Styliani; Walewska, Edyta; Belton, Christian; Galvao, Antonio; Okkenhaug, Hanneke; Yu, Lu; Nakhuda, Asif; Mansfield, Bill; Khan, Soumen; Oxley, David; Barragan, Montserrat; Kelsey, Gavin Share Save
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses Hornigold, Kirsti; Baker, Martin J.; Machin, Polly A.; Chetwynd, Stephen A.; Johnsson, Anna-Karin; Pantarelli, Chiara; Islam, Priota; Stammers, Melanie; Crossland, Laraine; Oxley, David; Okkenhaug, Hanneke; Walker, Simon; Walker, Rachael; Segonds-Pichon, Anne; Fukui, Yoshinori; Malliri, Angeliki; Welch, Heidi C. E. Share Save
PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate Chessa, Tamara A. M.; Jung, Piotr; Anwar, Arqum; Suire, Sabine; Anderson, Karen E.; Barneda, David; Kielkowska, Anna; Sadiq, Barzan A.; Lai, Ieng Wai; Felisbino, Sergio; Turnham, Daniel J.; Pearson, Helen B.; Phillips, Wayne A.; Sasaki, Junko; Sasaki, Takehiko; Oxley, David; Spensberger, Dominik; Segonds-Pichon, Anne; Wilson, Michael; Walker, Simon; Okkenhaug, Hanneke; Cosulich, Sabina; Hawkins, Phillip T.; Stephens, Len R. Share Save
Fission Yeast Iec1-Ino80-Mediated Nucleosome Eviction Regulates Nucleotide and Phosphate Metabolism Hogan, Cassandra Justine; Aligianni, Sofia; Durand-Dubief, Mickael; Persson, Jenna; Will, William R.; Webster, Judith; Wheeler, Linda; Mathews, Christopher K.; Elderkin, Sarah; Oxley, David; Ekwall, Karl; Varga-Weisz, Patrick Daniel Share Save
Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation Arez, Maria; Eckersley-Maslin, Melanie; Klobucar, Tajda; Lopes, Joao von Gilsa; Krueger, Felix; Mupo, Annalisa; Raposo, Ana Claudia; Oxley, David; Mancino, Samantha; Gendrel, Anne-Valerie; de Jesus, Bruno Bernardes; da Rocha, Simao Teixeira Share Save
Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses Hornigold, Kirsti; Chu, Julia Y.; Chetwynd, Stephen A.; Machin, Polly A.; Crossland, Laraine; Pantarelli, Chiara; Anderson, Karen E.; Hawkins, Phillip T.; Segonds-Pichon, Anne; Oxley, David; Welch, Heidi C. E. Share Save
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Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine Durgan, Joanne; Lystad, Alf H.; Sloan, Katherine; Carlsson, Sven R.; Wilson, Michael I.; Marcassa, Elena; Ulferts, Rachel; Webster, Judith; Lopez-Clavijo, Andrea F.; Wakelam, Michael J.; Beale, Rupert; Simonsen, Anne; Oxley, David; Florey, Oliver Share Save
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Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils Rynkiewicz, Natalie K.; Anderson, Karen E.; Suire, Sabine; Collins, Daniel M.; Karanasios, Eleftherios; Vadas, Oscar; Williams, Roger; Oxley, David; Clark, Jonathan; Stephens, Len R.; Hawkins, Phillip T. Share Save
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Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors Lochhead, Pamela A.; Tucker, Julie A.; Tatum, Natalie J.; Wang, Jinhua; Oxley, David; Kidger, Andrew M.; Johnson, Victoria P.; Cassidy, Megan A.; Gray, Nathanael S.; Noble, Martin E. M.; Cook, Simon J. Share Save
An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis Odle, Richard I.; Walker, Simon A.; Oxley, David; Kidger, Andrew M.; Balmanno, Kathryn; Gilley, Rebecca; Okkenhaug, Hanneke; Florey, Oliver; Ktistakis, Nicholas T.; Cook, Simon J. Share Save
MEK1/2 inhibitor withdrawal reverses acquired resistance driven by BRAFV600E amplification whereas KRASG13D amplification promotes EMT-chemoresistance Sale, Matthew J.; Balmanno, Kathryn; Saxena, Jayeta; Ozono, Eiko; Wojdyla, Katarzyna; McIntyre, Rebecca E.; Gilley, Rebecca; Woroniuk, Anna; Howarth, Karen D.; Hughes, Gareth; Dry, Jonathan R.; Arends, Mark J.; Caro, Pilar; Oxley, David; Ashton, Susan; Adams, David J.; Saez-Rodriguez, Julio; Smith, Paul D.; Cook, Simon J. Share Save
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Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes Smyrnias, Ioannis; Goodwin, Normann; Wachten, Dagmar; Skogestad, Jonas; Aronsen, Jan Magnus; Robinson, Emma L.; Demydenko, Kateryna; Segonds-Pichon, Anne; Oxley, David; Sadayappan, Sakthivel; Sipido, Karin; Bootman, Martin D.; Roderick, H. Llewelyn Share Save
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