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Thomas M. Vincent

regulus therapeutics inc.

8H-index
32Paper Count
1.6KCitation Count
Published Papers 9
Publication Date
The nucleobase guanine at the 3’-terminus of oligonucleotide RGLS4326 drives off-target AMPAR inhibition and CNS toxicity
err2025-11-28
err0
errOAAI
errTania Valencia; Laura Y. Yen; Cindy Berman; Thomas Vincent; Scott Davis; Francesca Varrone; Jianfeng Huang; Jessica Mastroianni; Morgan Carlson; Tate Owen; Amin Kamel; Denis Drygin; Garth A. Kinberger; Shanti Pal Gangwar; Maria V. Yelshanskaya; John Ridley; Robert Kirby; Jesus Alvarez; Ronak Lakhia; Vishal Patel; Alexander I. Sobolevsky; Edmund C. Lee
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A miR-221 multigene pharmacodynamic signature for assessing miR-221 inhibition
err2014-10-01
err0
PREAI
errPavlicek, Adam; Vincent, Thomas; Guicherit, Oivin; Chau, Nelson; Zabludoff, Sonya; Gibson, Neil; Lee, Edmund C.
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miR-221: A potential therapeutic target for hepatocellular carcinoma
err2014-10-01
err3
PREAI
errLee, Edmund C.; Xu, Jessica; Vincent, Thomas; Chen, Jie; Nelson, Michael; Huang, Xinqiang; Marcusson, Eric; Androsavich, John; Davis, Scott; Pavlicek, Adam; Gibson, Neil; Zabludoff, Sonya
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Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes
err2011-02-23
err264
errOAAI
errKoller, Erich; Vincent, Thomas M.; Chappell, Alfred; De, Soma; Manoharan, Muthiah; Bennett, C. Frank
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Matrix Metalloproteinase (MMP)-13 Regulates Mammary Tumor-Induced Osteolysis by Activating MMP9 and Transforming Growth Factor-β Signaling at the Tumor-Bone Interface
err2010-04-28
err108
errOAAI
errNannuru, Kalyan C.; Futakuchi, Mitsuru; Varney, Michelle L.; Vincent, Thomas M.; Marcusson, Eric G.; Singh, Rakesh K.
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Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity
err2007-09-04
err369
errOAAI
errGraff, Jeremy R.; Konicek, Bruce W.; Vincent, Thomas M.; Lynch, Rebecca L.; Monteith, David; Weir, Spring N.; Schwier, Phil; Capen, Andrew; Goode, Robin L.; Dowless, Michele S.; Chen, Yuefeng; Zhang, Hong; Sissons, Sean; Cox, Karen; McNulty, Ann M.; Parsons, Stephen H.; Wang, Tao; Sams, Lillian; Geeganage, Sandaruwan; Douglass, Larry E.; Neubauer, Blake Lee; Dean, Nicholas M.; Blanchard, Kerry; Shou, Jianyong; Stancato, Louis F.; Carter, Julia H.; Marcusson, Eric G.
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Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores
err2003-04-01
err251
errOAAI
errHarel, A; Orjalo, AV; Vincent, T; Lachish-Zalait, A; Vasu, S; Shah, S; Zimmerman, E; Elbaum, M; Forbes, DJ
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