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C

C. Frank Bennett

ionis pharmaceuticals

100H-index
331Paper Count
4.7WCitation Count
Published Papers 143
Publication Date
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Individualized antisense oligonucleotides for SCN2A-related developmental epileptic encephalopathy
errNature Medicine
IF50
err2026-07-21
err0
errOAAI
errOlivia Kim-McManus; Laurence Mignon; Julie Douville; He Pu; Catherine Parisien; Sarah Glass; C. Frank Bennett; Janelle Celso; Kendall Robbins; Hoameng Ung; Heather Olson; Stephen F. Kingsmore; Steven Petrou; Stanley T. Crooke; Joseph G. Gleeson; Elizabeth Berry-Kravis
errShare
errSave
Enhanced splicing modulation by NMA-modified antisense oligonucleotides
errNucleic Acids Research
IF13.1
err2026-05-21
err0
errOAAI
errKaren Ling; Thazha P Prakash; Jinghua Yu; Michaela Jackson; Seung J Chun; Gemma Bachmann; Noah Post; Sarah Greenlee; Armand Soriano; John L Hunyara; Daniel A Norris; Paymaan Jafar-nejad; Eric E Swayze; C Frank Bennett; Frank Rigo
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errSave
Preclinical evaluation of antisense oligonucleotide therapy in a mouse model of HNRNPH2-related neurodevelopmental disorder
errScience Translational Medicine
IF14.6
err2026-04-22
err0
PREAI
errAne Korff; Xiaojing Yang; Ozan Ozdemir; Ananya Samanta; Yong-Dong Wang; Tushar Patni; Alfonso J. Lavado; Anoop Murthy Kavirayani; Joseph Ochaba; Berit Powers; C. Frank Bennett; Hong Joo Kim; J. Paul Taylor
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errSave
Suppression of Huntington’s Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding
errNature Communications
IF15.7
err2025-11-14
err0
errOAAI
errElla W. Mathews; Sydney R. Coffey; Annette Gärtner; Jillian Belgrad; Robert M. Bragg; Daniel O’Reilly; Jeffrey P. Cantle; Cassandra McHugh; Ashley Summers; Joachim Fentz; Tom Schwagarus; Antje Cornelius; Ioannis Lingos; Zoe Burch; Marina Kovalenko; Marissa A. Andrew; C. Frank Bennett; Holly B. Kordasiewicz; Deanna M. Marchionini; Hilary Wilkinson; Thomas F. Vogt; Paolo Beuzer; Ricardo M. Pinto; Anastasia Khvorova; David Howland; Vanessa C. Wheeler; Jeffrey B. Carroll
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errSave
An alternative cytoplasmic SFPQ isoform with reduced phase separation potential is up-regulated in ALS
errScience Advances
IF12.5
err2025-08-22
err0
errOAAI
errJacob Neeves; Marija Petrić Howe; Oliver J. Ziff; Beth Callaghan; Daniel Jutzi; Koustav Pal; Theodoros I. Roumeliotis; Jyoti Choudhary; Adrian M. Isaacs; Frank Rigo; C. Frank Bennett; Marc-David Ruepp; Rickie Patani
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errSave
Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2025-05-14
err0
PREAI
errBorges, Beltran; Brown, Stephen M.; Chen, Wan-Jin; Clarke, Maria T.; Herzeg, Akos; Park, Jae Hong; Ross, Joshua; Kong, Lingling; Denton, Madeline; Smith, Amy K.; Lum, Tony; Zada, Fareha Moulana; Cordero, Marco; Gupta, Nalin; Cook, Sarah E.; Murray, Heather; Matson, John; Klein, Stephanie; Bennett, C. Frank; Krainer, Adrian R.; MacKenzie, Tippi C.; Sumner, Charlotte J.
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errSave
Tool to Resolve Distortions in Elemental and Isotopic Imaging
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-07-10
err0
PREAI
errLu, Chixiang; Chen, Gu; Song, Wenxin; Chen, Kai; Hee, Charmaine; Nikan, Mehran; Guagliardo, Paul; Bennett, C. Frank; Seth, Punit; Iyer, Killugudi Swaminathan; Young, Stephen G.; Qi, Xiaojuan; Jiang, Haibo
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errSave
Opportunities and challenges for innovative and equitable healthcare
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2024-02-26
err2
PREAI
errEcker, David J.; Aiello, Clarice D.; Arron, Joseph R.; Bennett, C. Frank; Bernard, Amy; Breakefield, Xandra O.; Broderick, Timothy J.; Callier, Shawneequa L.; Canton, Barry; Chen, Janice S.; Fishburn, C. Simone; Garrett, Banning; Hecht, Sidney M.; Janowitz, Tobias; Kliegman, Melinda; Krainer, Adrian; Louis, Chrystal U.; Lowe, Christopher; Sehgal, Alfica; Tozan, Yesim; Tracey, Kevin J.; Urnov, Fyodor; Wattendorf, Daniel; Williams, Thomas W.; Zhao, Xuanhe; Hayden, Michael R.
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errSave
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial (vol 29, pg 1437, 2023)
errNATURE MEDICINE
IF50
err2023-10-16
err0
errOAAI
errMummery, Catherine J.; Borjesson-Hanson, Anne; Blackburn, Daniel J.; Vijverberg, Everard G. B.; De Deyn, Peter Paul; Ducharme, Simon; Jonsson, Michael; Schneider, Anja; Rinne, Juha O.; Ludolph, Albert C.; Bodenschatz, Ralf; Kordasiewicz, Holly; Swayze, Eric E.; Fitzsimmons, Bethany; Mignon, Laurence; Moore, Katrina M.; Yun, Chris; Baumann, Tiffany; Li, Dan; Norris, Daniel A.; Crean, Rebecca; Graham, Danielle L.; Huang, Ellen; Ratti, Elena; Bennett, C. Frank; Junge, Candice; Lane, Roger M.
errShare
errSave
Antisense drugs for rare and ultra-rare genetic neurological diseases
errNEURON
IF15
err2023-08-01
err10
errOAAI
errMccauley, Madelyn E.; Bennett, C. Frank
errShare
errSave
GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells
errMOLECULAR THERAPY-NUCLEIC ACIDS
IF0
err2023-06-01
err4
errOAAI
errMcMahon, Moira A.; Rahdar, Meghdad; Mukhopadhyay, Swagatam; Bui, Huynh-Hoa; Hart, Christopher; Damle, Sagar; Courtney, Margo; Baughn, Michael W.; Cleveland, Don W.; Bennett, Frank
errShare
errSave
Personalized antisense oligonucleotides 'for free, for life' - the n-Lorem Foundation
errNATURE MEDICINE
IF50
err2023-05-11
err10
PREAI
errGleeson, Joseph G. G.; Bennett, C. Frank; Carroll, Jeffrey B. B.; Cole, Tracy; Douville, Julie; Glass, Sarah; Tekendo-Ngongang, Cedrik; Williford, Amy C. C.; Crooke, Stanley T. T.
errShare
errSave
Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer's disease: a phase 1b, randomized, placebo-controlled trial
errNATURE MEDICINE
IF50
err2023-04-24
err109
errOAAI
errMummery, Catherine J.; Borjesson-Hanson, Anne; Blackburn, Daniel J.; Vijverberg, Everard G. B.; De Deyn, Peter Paul; Ducharme, Simon; Jonsson, Michael; Schneider, Anja; Rinne, Juha O.; Ludolph, Albert C.; Bodenschatz, Ralf; Kordasiewicz, Holly; Swayze, Eric E.; Fitzsimmons, Bethany; Mignon, Laurence; Moore, Katrina M.; Yun, Chris; Baumann, Tiffany; Li, Dan; Norris, Daniel A.; Crean, Rebecca; Graham, Danielle L.; Huang, Ellen; Ratti, Elena; Bennett, C. Frank; Junge, Candice; Lane, Roger M.
errShare
errSave
Combinatorial ASO-mediated therapy with low dose SMN and the protective modifier Chp1 is not sufficient to ameliorate SMA pathology hallmarks
errNEUROBIOLOGY OF DISEASE
IF5.6
err2022-09-01
err4
PREAI
errMuinos-Buehl, A.; Rombo, R.; Janzen, E.; Ling, K. K.; Hupperich, K.; Rigo, F.; Bennett, C. F.; Wirth, B.
errShare
errSave
ASO-Based PKM Splice-Switching Therapy Inhibits Hepatocellular Carcinoma Growth
errCANCER RESEARCH
IF16.6
err2022-03-03
err50
errOAAI
errMa, Wai Kit; Voss, Dillon M.; Scharner, Juergen; Costa, Ana S. H.; Lin, Kuan-Ting; Jeon, Hyun Yong; Wilkinson, John E.; Jackson, Michaela; Rigo, Frank; Bennett, C. Frank; Krainer, Adrian R.
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errSave
Safety, tolerability and antiviral activity of the antisense oligonucleotide bepirovirsen in patients with chronic hepatitis B: a phase 2 randomized controlled trial
errNATURE MEDICINE
IF50
err2021-10-12
err97
errOAAI
errYuen, Man-Fung; Heo, Jeong; Jang, Jeong-Won; Yoon, Jung-Hwan; Kweon, Young-Oh; Park, Sung-Jae; Tami, Yvonne; You, Shihyun; Yates, Phillip; Tao, Yu; Cremer, Jennifer; Campbell, Fiona; Elston, Robert; Theodore, Dickens; Paff, Melanie; Bennett, C. Frank; Kwoh, T. Jesse
errShare
errSave
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS
errNATURE BIOTECHNOLOGY
IF41.7
err2021-08-12
err92
PREAI
errNagata, Tetsuya; Dwyer, Chrissa A.; Yoshida-Tanaka, Kie; Ihara, Kensuke; Ohyagi, Masaki; Kaburagi, Hidetoshi; Miyata, Haruka; Ebihara, Satoe; Yoshioka, Kotaro; Ishii, Takashi; Miyata, Kanjiro; Miyata, Kenichi; Powers, Berit; Igari, Tomoko; Yamamoto, Syunsuke; Arimura, Naoto; Hirabayashi, Hideki; Uchihara, Toshiki; Hara, Rintaro Iwata; Wada, Takeshi; Bennett, C. Frank; Seth, Punit P.; Rigo, Frank; Yokota, Takanori
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errSave
Treatment of infantile-onset spinal muscular atrophy with nusinersen: final report of a phase 2, open-label, multicentre, dose-escalation study
errLANCET CHILD & ADOLESCENT HEALTH
IF15.5
err2021-07-01
err59
PREAI
errFinkel, Richard S.; Chiriboga, Claudia A.; Vajsar, Jiri; Day, John W.; Montes, Jacqueline; De Vivo, Darryl C.; Schneider, Eugene; Bennett, C. Frank; Bishop, Kathie M.; Foster, Richard; Liu, Yingying; Ramirez-Schrempp, Danieia; Wong, Janice; Farwell, Wildon
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errSave
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome (vol 27, pg 526, 2021)
errNATURE MEDICINE
IF50
err2021-06-01
err0
errOAAI
errPuttaraju, Madaiah; Jackson, Michaela; Klein, Stephanie; Shilo, Asaf; Bennett, C. Frank; Gordon, Leslie; Rigo, Frank; Misteli, Tom
errShare
errSave
Modeling muscle regeneration in RNA toxicity mice
errHUMAN MOLECULAR GENETICS
IF3.2
err2021-04-16
err8
errOAAI
errYadava, Ramesh S.; Mandal, Mahua; Giese, Jack M.; Rigo, Frank; Bennett, C. Frank; Mahadevan, Mani S.
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errSave

Research Directions

No research directions
Co-authors
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J
Joseph L. Witztum
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K
Kazunori Kataoka
H-index: 153 · Papers: 1.1K
M
Michael R. Hayden
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