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Hetairos enables AI-based histopathological classification of CNS tumours Patel, Areeba; Jin, Darui; Shmatko, Artem; Rahmanzade, Ramin; Friederich, Lukas; Schrimpf, Daniel; Sievers, Philipp; Alhalabi, Obada; Rutz, Samuel; Suwala, Abigail; Sturm, Dominik; Wesseling, Pieter; Woehrer, Adelheid; Hou, Yanghao; Costa, Felipe D'almeida; Ille, Sebastian; Al-Hussaini, Maysa; Bertero, Luca; Schweizer, Leonille; Wiestler, Benedikt; Snuderl, Matija; Pfister, Stefan M.; Jones, David T. W.; Varlet, Pascale; Tauziede-Espariat, Arnault; Acker, Till; Brandner, Sebastian; Krieg, Sandro; Wick, Wolfgang; Bai, Xiangzhi; Von Deimling, Andreas; Gerstung, Moritz; Sahm, Felix Share Save
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AI-BASED HISTOPATHOLOGICAL CLASSIFICATION OF CENTRAL NERVOUS SYSTEM TUMOURS Jin, D.; Shmatko, A.; Patel, A.; Rahmanzade, R.; Friedrich, L.; Schrimpf, D.; Sievers, P.; Alhalabi, O.; Rutz, S. P.; Suwala, A. K.; Sturm, D.; Wesseling, P.; Woehrer, A.; Hou, Y.; D'almeida Costa, F.; Ille, S.; Al-Hussaini, M.; Bertero, L.; Schweizer, L.; Wiestler, B.; Snuderl, M.; Pfister, S. M.; Jones, D. T. W.; Varlet, P.; Tauziede-Espariat, A.; Acker, T.; Brandner, S.; Krieg, S. M.; Wick, W.; Bai, X.; von Deimling, A.; Gerstung, M.; Sahm, F. Share Save
SPATIAL HETEROGENEITY OF METHYLATION CLASSES IN MENINGIOMAS: IMPACT ON CLASSIFICATION ACCURACY AND CLINICAL PROGNOSIS Zettl, F.; Shmatko, A.; Patel, A.; Keller, F.; Hinz, F. E.; Maas, S. L.; Schweizer, L.; Preusser, M.; Berghaus, N.; von Deimling, A.; Gerstung, M.; Bludau, I; Sahm, F. Share Save
DECIPHERING GLIOBLASTOMA METABOLIC SIGNATURE: MOLECULAR PROFILING AND NADH-FLIM IMAGING Morelli, M.; Sandro, C.; Santonocito, O. S.; Lessi, F.; Ferri, G.; Menicagli, M.; Aretini, P.; Pieri, F.; Schweizer, L.; Ronellenfitsch, M.; Cesareo, V; Younan, N.; Ducray, F.; Tabouret, E.; Cuzzubbo, S.; Sanson, M.; Bielle, F.; Picca, A.; Garofano, L.; Iavarone, A.; Mazzanti, C.; Di Stefano, A. Share Save
COMPUTATIONAL HISTOPATHOLOGY ENABLES SCALABLE DEEP LEARNING-DRIVEN CNS TUMOR CLASSIFICATION FOR REAL-TIME INTRAOPERATIVE DIAGNOSTICS Keller, F.; Patel, A.; Aras, F. K.; Friedrich, L.; Banan, R.; Schrimpf, D.; Shmatko, A.; Zettl, F.; Gerstung, M.; Miarka, L.; Prinz, M.; Paulus, W.; Reifenberger, G.; Schweizer, L.; Schulz-Schaeffer, W.; Habel, A.; von Knebel-Doeberitz, M.; Sakowitz, O.; Geletneky, K.; Bludau, I; Sahm, F.; von Deimling, A.; Rahmanzade, R. Share Save
Distinct molecular profile and outcome of oligodendroglioma, IDH-mutant, 1p/19q-codeleted, and TERTp-wildtype: A grade 1 oligodendroglioma of young patients? Nozzoli, Filippo; Rahmanzade, Ramin; Schmid, Simone; Schweizer, Leonille; Schrimpf, Daniel; Friedel, Dennis; Go''bel, Kirsten; Reuss, David E.; Banan, Rouzbeh; Sievers, Philipp; Pusch, Stefan; Bogumil, Henri; Hinz, Felix; Suwala, Abigail K.; Aras, Fuat Kaan; Friedrich, Lukas; Osella-Abate, Simona; Ricci, Alessia Andrea; Macciotta, Alessandra; Simon, Thorsten; Fleischhack, Gudrun; Keyvani, Kathy; Hansford, Jordan R.; Khuong-Quang, Dong-Anh; Schucht, Philippe; Maragkou, Theoni; Juratli, Tareq A.; Meinhardt, Matthias; Zechel, Sabrina; Stadelmann, Christine; Coras, Roland; Sakowitz, Oliver W.; Goeppert, Benjamin; Schittenhelm, Jens; Etminan, Nima; Ratliff, Miriam; Herold-Mende, Christel; Pfister, Stefan M.; Wick, Wolfgang; Krieg, Sandro M.; von Deimling, Andreas; Sahm, Felix; Bertero, Luca Share Save
Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes Sievers, Philipp; Arora, Sonali; Hielscher, Thomas; Savran, Dilan; Schrimpf, Daniel; Banan, Rouzbeh; Vonhoeren, David; Pusch, Stefan; Sill, Martin; Appay, Romain; Wirsching, Hans-Georg; Hortobagyi, Tibor; Dohmen, Hildegard; Acker, Till; Kohlhof-Meinecke, Patricia; Schweizer, Leonille; Wefers, Annika K.; Harter, Patrick N.; Hartmann, Christian; Beschorner, Rudi; Schittenhelm, Jens; Behling, Felix; Tabatabai, Ghazaleh; Mawrin, Christian; Snuderl, Matija; Maas, Sybren L. N.; Wesseling, Pieter; Brandner, Sebastian; Korshunov, Andrey; Ratliff, Miriam; Krieg, Sandro M.; Wick, Wolfgang; Jones, David T. W.; Pfister, Stefan M.; Holland, Eric C.; von Deimling, Andreas; Szulzewsky, Frank; Sahm, Felix Share Save
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors Patel, Areeba; Goebel, Kirsten; Ille, Sebastian; Hinz, Felix; Schoebe, Natalie; Bogumil, Henri; Meyer, Jochen; Brehm, Michelle; Kardo, Helin; Schrimpf, Daniel; Lomakin, Artem; Ritter, Michael; Goeller, Pauline; Kerbs, Paul; Pfeifer, Lisa; Hamelmann, Stefan; Blume, Christina; Ippen, Franziska M.; Berghaus, Natalie; Euskirchen, Philipp; Schweizer, Leonille; Hultschig, Claus; Van Roy, Nadine; Van Dorpe, Jo; van der Meulen, Joni; Loontiens, Siebe; Dedeurwaerdere, Franceska; Leske, Henning; Halldorsson, Skarpheoinn; Fox, Graeme; Deacon, Simon; Cahyani, Inswasti; Holmes, Nadine; Wibowo, Satrio; Munro, Rory; Martin, Dan; Sharif, Abid; Housley, Mark; Goldspring, Robert; Brandner, Sebastian; Roy, Somak; Hench, Juergen; Frank, Stephan; Unterberg, Andreas; Goidts, Violaine; Jaeger, Natalie; Paine, Simon; Smith, Stuart; Herold-Mende, Christel; Pfister, Stefan M.; Vik-Mo, Einar O.; von Deimling, Andreas; Krieg, Sandro; Jones, David T. W.; Loose, Matthew; Schlesner, Matthias; Sill, Martin Share Save
European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection Sahm, Felix; Bertero, Luca; Brandner, Sebastian; Capper, David; Goldbrunner, Roland; Jenkinson, Michael D.; Kalamarides, Michel; Lamszus, Katrin; Albert, Nathalie L.; Mair, Maximilian J.; Berghoff, Anna S.; Mawrin, Christian; Wirsching, Hans-Georg; Maas, Sybren L. N.; Raleigh, David R.; Reifenberger, Guido; Schweizer, Leonille; Suwala, Abigail K.; Tabatabai, Ghazaleh; Tabouret, Emeline; Short, Susan; Wen, Patrick Y.; Weller, Michael; Le Rhun, Emilie; Wesseling, Pieter; van den Bent, Martin; Preusser, Matthias Share Save
DECIPHERING GLIOBLASTOMA METABOLIC SIGNATURE: MOLECULAR PROFILING AND NADH-FLIM IMAGING Morelli, M.; Santonocito, O.; Lessi, F.; Ferri, G.; Menicagli, M.; Aretini, P.; Grimod, G.; Gambacciani, C.; Pieri, F.; Schweizer, L.; Ronellenfitsch, M.; Sanson, M.; Picca, A.; Garofano, L.; Iavarone, A.; Mazzanti, C.; Di Stefano, A. Share Save
Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection-Update 1 van den Bent, Martin J.; Franceschi, Enrico; Touat, Mehdi; French, Pim J.; Idbaih, Ahmed; Lombardi, Giuseppe; Ruda, Roberta; Schweizer, Leonille; Capper, David; Sanson, Marc; Wesseling, Pieter; Weller, Michael; Eoli, Marica; Anghileri, Elena; Bielle, Franck; Euskirchen, Phillipp; Geurts, Marjolein; Wen, Patrick Y.; Preusser, Matthias Share Save
Targeted whole-viral genome sequencing from formalin-fixed paraffin-embedded neuropathology specimens Gorissen, Charlotte; Albers, Anne; Ruf, Viktoria; Chteinberg, Emil; Siebert, Reiner; Schweizer, Leonille; Kaufmann, Lukas; Kuehn, Joachim E.; Tappe, Dennis; Kuhlmann, Tanja; Thomas, Christian Share Save
Integrated analyses reveal two molecularly and clinically distinct subtypes of H3 K27M-mutant diffuse midline gliomas with prognostic significance Stegat, Lotte; Eckhardt, Alicia; Gocke, Antonia; Neyazi, Sina; Pohl, Lara; Schmid, Simone; Dottermusch, Matthias; Frank, Stephan; Pinnschmidt, Hans; Herms, Jochen; Glatzel, Markus; Snuderl, Matija; Schweizer, Leonille; Thomas, Christian; Neumann, Julia; Dorostkar, Mario M.; Schueller, Ulrich; Wefers, Annika K. Share Save
Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations Sievers, Philipp; Bielle, Franck; Goebel, Kirsten; Schrimpf, Daniel; Nichelli, Lucia; Mathon, Bertrand; Appay, Romain; Boldt, Henning B.; Dohmen, Hildegard; Selignow, Carmen; Acker, Till; Vicha, Ales; Martinetto, Horacio; Schweizer, Leonille; Schueller, Ulrich; Brandner, Sebastian; Wesseling, Pieter; Schmid, Simone; Capper, David; Abdullaev, Zied; Aldape, Kenneth; Korshunov, Andrey; Krieg, Sandro M.; Wick, Wolfgang; Pfister, Stefan M.; von Deimling, Andreas; Reuss, David E.; Jones, David T. W.; Sahm, Felix Share Save
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Clinical implications of DNA methylation-based integrated classification of histologically defined grade 2 meningiomas (vol 12, pg 74, 2024) Ehret, Felix; Perez, Eilis; Teichmann, Daniel; Meier, Sandra; Geiler, Carola; Zeus, Cosmas; Franke, Helene; Roohani, Siyer; Wasilewski, David; Onken, Julia; Vajkoczy, Peter; Schweizer, Leonille; Kaul, David; Capper, David Share Save
Clinical implications of DNA methylation-based integrated classification of histologically defined grade 2 meningiomas Ehret, Felix; Perez, Eilis; Teichmann, Daniel; Meier, Sandra; Geiler, Carola; Cosmas, Zeus; Franke, Helene; Roohani, Siyer; Wasilewksi, David; Onken, Julia; Vajkoczy, Peter; Schweizer, Leonille; Kaul, David; Capper, David Share Save
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